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Search Results to Linda R Watkins

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Watkins, Linda

One or more keywords matched the following items that are connected to Watkins, Linda

Item Type	Name
Academic Article	Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions.
Academic Article	Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10.
Academic Article	Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain.
Academic Article	The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia.
Academic Article	Release of plasmid DNA-encoding IL-10 from PLGA microparticles facilitates long-term reversal of neuropathic pain following a single intrathecal administration.
Academic Article	Below level central pain induced by discrete dorsal spinal cord injury.
Academic Article	Intraneural dexamethasone applied simultaneously to rat sciatic nerve constriction delays the development of hyperalgesia and allodynia.
Academic Article	Unilateral T13 and L1 dorsal root avulsion: methods for a novel model of central neuropathic pain.
Academic Article	(+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats.
Academic Article	Understanding chronic inflammatory and neuropathic pain.
Academic Article	A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4.
Academic Article	Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.
Academic Article	Peri-sciatic proinflammatory cytokines, reactive oxygen species, and complement induce mirror-image neuropathic pain in rats.
Academic Article	Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4).
Academic Article	Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy.
Academic Article	Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes.
Academic Article	Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain.
Academic Article	Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.
Academic Article	The glial modulatory drug AV411 attenuates mechanical allodynia in rat models of neuropathic pain.
Academic Article	Long-term control of neuropathic pain in a non-viral gene therapy paradigm.
Academic Article	Immunological priming potentiates non-viral anti-inflammatory gene therapy treatment of neuropathic pain.
Academic Article	An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo.
Academic Article	Commentary on Landry et al.: "Propentofylline, a CNS glial modulator, does not decrease pain in post-herpetic neuralgia patients: in vitro evidence for differential responses in human and rodent microglia and macrophages".
Academic Article	Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male Sprague Dawley rats.
Concept	Neuralgia
Concept	Neuralgia, Postherpetic
Academic Article	Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.
Academic Article	Systemic administration of propentofylline, ibudilast, and (+)-naltrexone each reverses mechanical allodynia in a novel rat model of central neuropathic pain.
Academic Article	Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations.
Academic Article	Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPAR? mechanisms.
Academic Article	The therapeutic potential of interleukin-10 in neuroimmune diseases.
Academic Article	Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation.
Academic Article	Prior voluntary wheel running attenuates neuropathic pain.
Academic Article	Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury.
Academic Article	Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy.
Academic Article	Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia.
Grant	Pain facilitation via neuron-to-glia signaling
Grant	Immune and Gilia Regulation of Pain & Analgesic Actions
Grant	Preventing Transition of Acute-to-Chronic Neuropathic Pain: Models, Mechanisms &
Grant	Spinal adenosine modulator: enduring anti-inflammatory action in neuropathic pain
Grant	Optoid Analgesics: Modulation of Trigeminal &Spinal Glial Activation
Grant	Targeting toll like receptor 4 (TLR4) and TLR2 to resolve EAE-associated paralysis, pain and cognitive deficits: efficacy of a clinically-relevant blood brain barrier permeable TLR4/TLR2 antagonist
Grant	Models and mechanisms for the transition of acute-to-chronic orofacial pain
Grant	Targeting neuropathic pain prevention: Modulating the neuroimmunology of peripheral nerve injury
Academic Article	Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury.
Academic Article	Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats.
Academic Article	DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats.
Academic Article	Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A2A receptor agonists.
Academic Article	MicroRNA-124 and microRNA-146a both attenuate persistent neuropathic pain induced by morphine in male rats.
Grant	Enduring reversal of chronic pain by adenosine 2a agonism
Grant	Enduring enhancement of neuropathic pain by early post-trauma morphine
Academic Article	A single peri-sciatic nerve administration of the adenosine 2A receptor agonist ATL313 produces long-lasting anti-allodynia and anti-inflammatory effects in male rats.
Academic Article	Oxycodone, fentanyl, and morphine amplify established neuropathic pain in male rats.
Academic Article	Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.
Academic Article	Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists.
Academic Article	Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury.
Academic Article	Preconditioning by voluntary wheel running attenuates later neuropathic pain via nuclear factor E2-related factor 2 antioxidant signaling in rats.
Academic Article	Intrathecal non-viral interleukin-10 gene therapy ameliorates neuropathic pain as measured by both classical static allodynia and a novel supra-spinally mediated pain assay, the Two-Arm Rodent Somatosensory (TARS) task.
Academic Article	Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats.
Academic Article	Voluntary wheel running prevents formation of membrane attack complexes and myelin degradation after peripheral nerve injury.

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Neuralgia