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Search Results to Timothy A McKinsey

This is a "connection" page, showing the details of why an item matched the keywords from your search.


One or more keywords matched the following items that are connected to McKinsey, Timothy

Item TypeName
Academic Article Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation.
Academic Article Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors.
Academic Article Protein kinase D directly phosphorylates histone deacetylase 5 via a random sequential kinetic mechanism.
Academic Article Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis.
Academic Article Isoform-selective HDAC inhibitors: closing in on translational medicine for the heart.
Academic Article Targeting inflammation in heart failure with histone deacetylase inhibitors.
Academic Article Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Academic Article Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5.
Academic Article Therapeutic potential for HDAC inhibitors in the heart.
Academic Article Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Academic Article Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.
Academic Article Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5.
Academic Article Toward transcriptional therapies for the failing heart: chemical screens to modulate genes.
Academic Article Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy.
Academic Article Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.
Academic Article Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.
Academic Article Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.
Academic Article A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase.
Academic Article Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors.
Academic Article Targeting histone deacetylases for heart failure.
Academic Article ?-Adrenergic receptor stimulation and activation of protein kinase A protect against a1-adrenergic-mediated phosphorylation of protein kinase D and histone deacetylase 5.
Academic Article The biology and therapeutic implications of HDACs in the heart.
Academic Article Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.
Concept Histone Deacetylase 1
Concept Histone Deacetylase Inhibitors
Concept Histone Deacetylase 2
Academic Article Estrogen regulates histone deacetylases to prevent cardiac hypertrophy.
Academic Article Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes.
Academic Article Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.
Academic Article HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Academic Article Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy.
Academic Article Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism.
Academic Article Acetyl-lysine erasers and readers in the control of pulmonary hypertension and right ventricular hypertrophy.
Academic Article Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle.
Academic Article Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement.
Academic Article Non-sirtuin histone deacetylases in the control of cardiac aging.
Academic Article Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ.
Academic Article Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension.
Academic Article The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases.
Academic Article Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes.
Academic Article Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.
Grant Isoform-Selective HDAC Inhibitors for Age-Associated Diastolic Dysfunction
Academic Article Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy.
Academic Article Class I HDACs control a JIP1-dependent pathway for kinesin-microtubule binding in cardiomyocytes.
Academic Article Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Concept Histone Deacetylase 6
Academic Article HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Academic Article Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor.
Academic Article Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition.
Academic Article HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Academic Article Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity.
Academic Article HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Academic Article Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies.
Academic Article HDAC11 inhibition triggers bimodal thermogenic pathways to circumvent adipocyte catecholamine resistance.

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  • Histone Deacetylase 2

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