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Search Results to Thomas R Cech

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Cech, Thomas

One or more keywords matched the following items that are connected to Cech, Thomas

Item Type	Name
Academic Article	Efficient protein-facilitated splicing of the yeast mitochondrial bI5 intron.
Academic Article	Protein facilitation of group I intron splicing by assembly of the catalytic core and the 5' splice site domain.
Academic Article	Telomerase RNA localized in the replication band and spherical subnuclear organelles in hypotrichous ciliates.
Academic Article	Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.
Academic Article	Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine.
Academic Article	Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit.
Academic Article	The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA.
Academic Article	Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.
Academic Article	Regulation of telomere length and function by a Myb-domain protein in fission yeast.
Academic Article	Polyadenylation of telomerase RNA in budding yeast.
Academic Article	Telomerase and chromosome end maintenance.
Academic Article	Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere-binding protein.
Academic Article	Oxytricha telomere-binding protein: DNA-dependent dimerization of the alpha and beta subunits.
Academic Article	Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle.
Academic Article	Assembly of a ribonucleoprotein catalyst by tertiary structure capture.
Academic Article	Modulation of telomerase activity by telomere DNA-binding proteins in Oxytricha.
Academic Article	Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex.
Academic Article	The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.
Academic Article	Human POT1 facilitates telomere elongation by telomerase.
Academic Article	RNA finds a simpler way.
Academic Article	Tetrahymena telomerase is active as a monomer.
Academic Article	Binding of the CBP2 protein to a yeast mitochondrial group I intron requires the catalytic core of the RNA.
Academic Article	Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection.
Academic Article	Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.
Academic Article	Soluble domains of telomerase reverse transcriptase identified by high-throughput screening.
Academic Article	Switching human telomerase on and off with hPOT1 protein in vitro.
Academic Article	A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro.
Academic Article	POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
Academic Article	Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Academic Article	Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance.
Academic Article	Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein.
Academic Article	Crawling out of the RNA world.
Academic Article	Biological catalysis by RNA.
Academic Article	How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Academic Article	Functional interaction between telomere protein TPP1 and telomerase.
Academic Article	Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants.
Academic Article	Structural biology. The ribosome is a ribozyme.
Academic Article	Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase.
Academic Article	Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.
Academic Article	Pot1, the putative telomere end-binding protein in fission yeast and humans.
Academic Article	Two versions of the gene encoding the 41-kilodalton subunit of the telomere binding protein of Oxytricha nova.
Academic Article	Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model.
Academic Article	The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.
Academic Article	Finding the end: recruitment of telomerase to telomeres.
Academic Article	Phosphorylation of the Oxytricha telomere protein: possible cell cycle regulation.
Academic Article	DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.
Academic Article	Beginning to understand the end of the chromosome.
Academic Article	Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n.
Academic Article	Catalytic RNA: structure and mechanism.
Academic Article	Reverse transcriptase motifs in the catalytic subunit of telomerase.
Academic Article	Molecular cloning of telomere-binding protein genes from Stylonychia mytilis.
Academic Article	Telomerase catalytic subunit homologs from fission yeast and human.
Academic Article	Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity.
Academic Article	Two modes of survival of fission yeast without telomerase.
Academic Article	Protection of telomeres by the Ku protein in fission yeast.
Academic Article	Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting.
Academic Article	The POT1-TPP1 telomere complex is a telomerase processivity factor.
Academic Article	Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction.
Academic Article	N-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complex.
Academic Article	Sequence-specific and 3'-end selective single-strand DNA binding by the Oxytricha nova telomere end binding protein alpha subunit.
Academic Article	The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro.
Academic Article	Global expression changes resulting from loss of telomeric DNA in fission yeast.
Academic Article	RNA as a flexible scaffold for proteins: yeast telomerase and beyond.
Academic Article	Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.
Academic Article	Oxytricha telomeric nucleoprotein complexes reconstituted with synthetic DNA.
Academic Article	Tetrahymena telomerase protein p65 induces conformational changes throughout telomerase RNA (TER) and rescues telomerase reverse transcriptase and TER assembly mutants.
Academic Article	Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p.
Academic Article	Oligomerization of intervening sequence RNA molecules in the absence of proteins.
Academic Article	POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.
Academic Article	Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP.
Academic Article	Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.
Academic Article	DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe.
Academic Article	Properties of the telomeric DNA-binding protein from Oxytricha nova.
Academic Article	RNase P branches out from RNP to protein: organelle-triggered diversification?
Academic Article	RNA recognition by the DNA end-binding Ku heterodimer.
Academic Article	Telomeric DNA-protein interactions of Oxytricha macronuclear DNA.
Concept	Homeodomain Proteins
Concept	Ribosomal Proteins
Concept	Archaeal Proteins
Concept	Adaptor Proteins, Signal Transducing
Concept	DNA-Binding Proteins
Concept	Co-Repressor Proteins
Concept	Green Fluorescent Proteins
Concept	Bacterial Proteins
Concept	Recombinant Fusion Proteins
Concept	Capsid Proteins
Concept	Fungal Proteins
Concept	Saccharomyces cerevisiae Proteins
Concept	Carrier Proteins
Concept	Cell Cycle Proteins
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	Neoplasm Proteins
Concept	snRNP Core Proteins
Concept	Arabidopsis Proteins
Concept	Telomere-Binding Proteins
Concept	Proto-Oncogene Proteins
Concept	Protozoan Proteins
Concept	RNA-Binding Proteins
Concept	Repressor Proteins
Concept	Schizosaccharomyces pombe Proteins
Concept	Proto-Oncogene Proteins c-myb
Concept	Proteins
Academic Article	Many disease-associated variants of hTERT retain high telomerase enzymatic activity.
Academic Article	DNA-protein interactions in the Drosophila melanogaster mitochondrial genome as deduced from trimethylpsoralen crosslinking patterns.
Academic Article	Promiscuous RNA binding by Polycomb repressive complex 2.
Academic Article	Inhibition of telomerase recruitment and cancer cell death.
Academic Article	Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA.
Academic Article	A dimeric state for PRC2.
Academic Article	Identification of human TERT elements necessary for telomerase recruitment to telomeres.
Academic Article	Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.
Academic Article	Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.
Academic Article	Biochemical Properties and Biological Functions of FET Proteins.
Academic Article	Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.
Academic Article	Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres.
Grant	Telomerase and Telomeres: Structure, Function and Regulation
Grant	CHROMATIN STRUCTURE OF A TRANSCRIPTION UNIT
Academic Article	How do lncRNAs regulate transcription?
Academic Article	Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity.
Academic Article	Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA.
Academic Article	Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits.
Academic Article	Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA.
Concept	Pancreatitis-Associated Proteins
Concept	Maltose-Binding Proteins
Concept	Polycomb-Group Proteins
Academic Article	Regulation of histone methylation by automethylation of PRC2.
Academic Article	The structure of human CST reveals a decameric assembly bound to telomeric DNA.
Academic Article	RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells.
Academic Article	Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells.
Academic Article	Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization.
Academic Article	CST does not evict elongating telomerase but prevents initiation by ssDNA binding.
Academic Article	RNA in biological condensates.
Academic Article	Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search.

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