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Search Results to Thomas R Cech

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One or more keywords matched the following items that are connected to Cech, Thomas

Item TypeName
Academic Article Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu).
Academic Article GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain.
Academic Article Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine.
Academic Article Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit.
Academic Article Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.
Academic Article Conformational switches involved in orchestrating the successive steps of group I RNA splicing.
Academic Article RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme.
Academic Article The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena.
Academic Article Joining the two domains of a group I ribozyme to form the catalytic core.
Academic Article Crystals by design: a strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron.
Academic Article Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes.
Academic Article An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme.
Academic Article Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.
Academic Article Self-splicing of the group I intron from Anabaena pre-tRNA: requirement for base-pairing of the exons in the anticodon stem.
Academic Article In vitro selection of RNAs with increased tertiary structure stability.
Academic Article Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis.
Academic Article Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features.
Academic Article The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.
Academic Article Binding of the CBP2 protein to a yeast mitochondrial group I intron requires the catalytic core of the RNA.
Academic Article Alternative secondary structures in the 5' exon affect both forward and reverse self-splicing of the Tetrahymena intervening sequence RNA.
Academic Article Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase.
Academic Article Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model.
Academic Article Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity.
Academic Article Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity.
Concept Mutagenesis, Site-Directed
Concept Mutagenesis
Concept Mutagenesis, Insertional
Grant NUCLEIC ACID STRUCTURE AND REACTIVITY
Academic Article Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools.

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  • Mutagenesis

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