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Search Results to Thomas R Cech

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Cech, Thomas

One or more keywords matched the following items that are connected to Cech, Thomas

Item Type	Name
Academic Article	Catalysis of RNA cleavage by a ribozyme derived from the group I intron of Anabaena pre-tRNA(Leu).
Academic Article	GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain.
Academic Article	Telomeric protein-DNA point contacts identified by photo-cross-linking using 5-bromodeoxyuridine.
Academic Article	Oxytricha telomere-binding protein: separable DNA-binding and dimerization domains of the alpha-subunit.
Academic Article	Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.
Academic Article	Conformational switches involved in orchestrating the successive steps of group I RNA splicing.
Academic Article	RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme.
Academic Article	The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena.
Academic Article	Joining the two domains of a group I ribozyme to form the catalytic core.
Academic Article	Crystals by design: a strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron.
Academic Article	Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes.
Academic Article	An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme.
Academic Article	Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.
Academic Article	Self-splicing of the group I intron from Anabaena pre-tRNA: requirement for base-pairing of the exons in the anticodon stem.
Academic Article	In vitro selection of RNAs with increased tertiary structure stability.
Academic Article	Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis.
Academic Article	Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features.
Academic Article	The Euplotes La motif protein p43 has properties of a telomerase-specific subunit.
Academic Article	Binding of the CBP2 protein to a yeast mitochondrial group I intron requires the catalytic core of the RNA.
Academic Article	Alternative secondary structures in the 5' exon affect both forward and reverse self-splicing of the Tetrahymena intervening sequence RNA.
Academic Article	Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase.
Academic Article	Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model.
Academic Article	Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity.
Academic Article	Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity.
Concept	Mutagenesis, Site-Directed
Concept	Mutagenesis
Concept	Mutagenesis, Insertional
Grant	NUCLEIC ACID STRUCTURE AND REACTIVITY
Academic Article	Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools.

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Mutagenesis