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Search Results to Peter James Dempsey

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Dempsey, Peter

One or more keywords matched the following items that are connected to Dempsey, Peter

Item Type	Name
Academic Article	A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16.
Academic Article	Metalloproteases regulate T-cell proliferation and effector function via LAG-3.
Academic Article	The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Academic Article	ADAM10 as a target for anti-cancer therapy.
Academic Article	ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.
Academic Article	Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.
Academic Article	ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.
Academic Article	Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
Academic Article	ADAM10 as a therapeutic target for cancer and inflammation.
Concept	Amyloid beta-Protein Precursor
Concept	Amyloid Precursor Protein Secretases
Academic Article	ADAM10 regulates Notch function in intestinal stem cells of mice.
Academic Article	Constitutive a- and ?-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.
Academic Article	Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
Academic Article	Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.

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Amyloid