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Search Results to Peter James Dempsey

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One or more keywords matched the following items that are connected to Dempsey, Peter

Item TypeName
Academic Article A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16.
Academic Article Metalloproteases regulate T-cell proliferation and effector function via LAG-3.
Academic Article The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Academic Article ADAM10 as a target for anti-cancer therapy.
Academic Article ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.
Academic Article Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.
Academic Article ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.
Academic Article Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
Academic Article ADAM10 as a therapeutic target for cancer and inflammation.
Concept Amyloid beta-Protein Precursor
Concept Amyloid Precursor Protein Secretases
Academic Article ADAM10 regulates Notch function in intestinal stem cells of mice.
Academic Article Constitutive a- and ß-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.
Academic Article Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.

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  • Amyloid

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