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Search Results to Peter James Dempsey

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One or more keywords matched the following items that are connected to Dempsey, Peter

Item TypeName
Academic Article A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16.
Academic Article Metalloproteases regulate T-cell proliferation and effector function via LAG-3.
Academic Article The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Academic Article ADAM10 as a target for anti-cancer therapy.
Academic Article ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.
Academic Article Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.
Academic Article ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.
Academic Article Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
Academic Article ADAM10 as a therapeutic target for cancer and inflammation.
Academic Article ADAM10 regulates Notch function in intestinal stem cells of mice.
Academic Article Constitutive a- and ?-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.
Academic Article Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.
Academic Article Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury.
Concept ADAM10 Protein
Academic Article Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.
Academic Article Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis.

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  • ADAM10 Protein

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