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Search Results to John W Kappler

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Item TypeName
Academic Article Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ.
Academic Article Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule.
Academic Article Antigen-specific and nonspecific mediators of T cell/B cell cooperation. V. Unresponsiveness to HGG in vitro of these two T cell subpopulations.
Academic Article Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy.
Academic Article The frequency and activity of single helper T cells.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells.
Academic Article Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes.
Academic Article The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays.
Academic Article Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.
Academic Article Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas.
Academic Article Use of I region-restricted, antigen-specific T cell hybridomas to produce idiotypically specific anti-receptor antibodies.
Academic Article Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells.
Academic Article The role of H-2 linked genes in helper T-cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper T cells each specific for antigen and one set of parental H-2 products.
Academic Article Flow sorting of antigen-binding B cell subsets.
Academic Article The capacity of murine alveolar macrophages to stimulate antigen-dependent T-lymphocyte activation and proliferation.
Academic Article Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.
Academic Article Helper signals in the plaque-forming cell response to protein-bound haptens.
Academic Article A requirement for nonspecific T cell factors in antibody responses to "T cell independent" antigens.
Academic Article Use of somatic cell genetics to study chromosomes contributing to antigen plus I recognition by T cell hybridomas.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.
Academic Article Biochemistry and distribution of the T cell receptor.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.
Academic Article An IL 2-secreting T cell hybridoma that responds to a self class I histocompatibility antigen in the H-2D region.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides.
Academic Article The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas.
Academic Article Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines.
Academic Article The two high responder haplotypes to (TG)-A--L do not cross-react in the helper T cell level.
Academic Article Concanavalin A-inducible, interleukin-2-producing T cell hybridoma.
Academic Article Functional subsets of B cells defined by quantitative differences in surface I-A.
Academic Article Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help.
Academic Article Antigen presentation to T cell hybridomas by a macrophage cell line: an inducible function.
Academic Article Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas.
Academic Article Functional heterongeneity among the T-derived lymphocytes of the mouse. VI. Memory T cells stored in the T2 subpopulation.
Academic Article Functional heterogeneity among the T-derived lymphocytes of the mouse. II. Sensitivity of subpopulations to anti-thymocyte serum.
Academic Article Functional heterogeneity among the T-derived lymphocytes of the mouse. V. Response kinetics of peripheral T cell subpopulations.
Academic Article Functional heterogeneity among the T-derived lymphocytes of the mouse. III. Helper and suppressor T-cells activated by concanavalin A.
Academic Article The role of H-2-linked genes in helper T-cell function. III. Expression of immune response genes for trinitrophenyl conjugates of poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in B cells and macrophages.
Academic Article Processing and major histocompatibility complex binding of the MTV7 superantigen.
Academic Article The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression.
Academic Article The open reading frames in the 3' long terminal repeats of several mouse mammary tumor virus integrants encode V beta 3-specific superantigens.
Academic Article Stimulation with specific antigen can block superantigen-mediated deletion of T cells in vivo.
Academic Article Identification of two V beta 7-specific viral superantigens.
Academic Article The kinetics of DNA methylation in cultures of a mouse adrenal cell line.
Academic Article Regulation of the immune response. 3. Kinetic differences between thymus- and bone marrow- derived lymphocytes in the proliferative response to heterologous erythrocytes.
Academic Article A micro-technique for hemolytic plaque assays.
Academic Article The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions.
Academic Article Superantigens and their potential role in human disease.
Academic Article Functional heterogeneity among the T-derived lymphocytes of the mouse. VII. Conversion of T1 cells to T2 cells by antigen.
Academic Article Thymic epithelial cell lines that mediate positive selection can also induce thymocyte clonal deletion.
Academic Article Antigen-specific and nonspecific mediators of T-cell/B-cell cooperation. VI. Distinct patterns of cross-reactivity by two human gamma-globulin-primed helper T-cell subpopulations.
Academic Article Two types of functionally distinct, synergizing helper T cells.
Academic Article Automated fluorescent analysis for cytotoxicity assays.
Academic Article Antigen-specific, H-2-restricted helper T cell hybridomas.
Academic Article Binding of antigen-specific, H-2-restricted T cell hybridomas to antigen-pulsed adherent cell monolayers.
Academic Article T cell tolerance. Giles F. Filley Lecture.
Academic Article The effects of chronic infection with a superantigen-producing virus.
Academic Article The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma.
Academic Article Coordinate production by a T cell hybridoma of gamma interferon and three other lymphokine activities: multiple activities of a single lymphokine?
Academic Article Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen.
Academic Article Mutations defining functional regions of the superantigen staphylococcal enterotoxin B.
Academic Article Role of gamma-interferon in antibody-producing responses.
Academic Article The responses of mature T cells are not necessarily antagonized by their positively selecting peptide.
Academic Article Interleukin-induced increase in Ia expression by normal mouse B cells.
Academic Article Functional heterogeneity among the T-derived lymphocytes of the mouse. IV. Nature of spontaneously induced suppressor cells.
Academic Article Development and function of T cells in T cell antigen receptor/CD3 zeta knockout mice reconstituted with Fc epsilon RI gamma.
Academic Article Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice.
Academic Article Positive selection of thymocytes bearing alpha beta T cell receptors.
Academic Article Transcytosis of staphylococcal superantigen toxins.
Academic Article Helper T cells recognise antigen and macrophage surface components simultaneously.
Academic Article Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells.
Academic Article Cytokine-induced survival of activated T cells in vitro and in vivo.
Academic Article T cell positive selection by a high density, low affinity ligand.
Academic Article Selection of antigen-specific T cells by a single IEk peptide combination.
Academic Article CD8+ T-cell clones in old mice.
Academic Article Targeting the T cell receptor in rheumatoid arthritis.
Academic Article CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection.
Academic Article Production of soluble MHC class II proteins with covalently bound single peptides.
Academic Article Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor.
Academic Article Positive selection of TcR alpha beta thymocytes: is cortical thymic epithelium an obligatory participant in the presentation of major histocompatibility complex protein?
Academic Article The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells.
Academic Article Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a).
Academic Article Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins.
Academic Article Genomic-scale analysis of gene expression in resting and activated T cells.
Academic Article Activation changes the spectrum but not the diversity of genes expressed by T cells.
Academic Article Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis.
Academic Article Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling.
Academic Article B cells are not essential for peripheral T-cell tolerance.
Academic Article Immunological adjuvants promote activated T cell survival via induction of Bcl-3.
Academic Article T cells compete for access to antigen-bearing antigen-presenting cells.
Academic Article The growth of the very large CD8+ T cell clones in older mice is controlled by cytokines.
Academic Article A method for production of antibodies to human T-cell receptor beta-chain variable regions.
Academic Article TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers.
Academic Article IL-6 rescues resting mouse T cells from apoptosis.
Academic Article T cells down-modulate peptide-MHC complexes on APCs in vivo.
Academic Article Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4.
Academic Article Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo.
Academic Article Stronger correlation of bcl-3 than bcl-2, bcl-xL, costimulation, or antioxidants with adjuvant-induced T cell survival.
Academic Article The antigen specificity of thymus-derived helper cells.
Academic Article Regulation of the immune response. II. Qualitative and quantitative differences between thymus- and bone marrow-derived lymphocytes in the recognition of antigen.
Academic Article Multiple mechanisms of T cell tolerance to Mls-1a.
Academic Article T cell apoptosis and reactive oxygen species.
Academic Article A maternally inherited superantigen encoded by a mammary tumour virus.
Academic Article Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma.
Academic Article Mast cell-dependent migration of effector CD8+ T cells through production of leukotriene B4.
Academic Article Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library.
Academic Article Analysis of the interaction site for the self superantigen Mls-1a on T cell receptor V beta.
Academic Article Evidence for the effects of a superantigen in rheumatoid arthritis.
Academic Article An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder.
Academic Article Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells.
Academic Article Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice.
Academic Article Promotion of B cell immune responses via an alum-induced myeloid cell population.
Academic Article Using a baculovirus display library to identify MHC class I mimotopes.
Academic Article Analysis of class II MHC structure in thymic nurse cells.
Academic Article Loss of Bim allows precursor B cell survival but not precursor B cell differentiation in the absence of interleukin 7.
Academic Article Bystander virus infection prolongs activated T cell survival.
Academic Article The role of the T cell receptor in positive and negative selection of developing T cells.
Academic Article Non-malignant clonal expansions of CD8+ memory T cells in aged individuals.
Academic Article How the T cell repertoire becomes peptide and MHC specific.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983.
Academic Article Loss of the proapoptotic protein, Bim, breaks B cell anergy.
Academic Article Homeostasis of the memory T cell pool.
Academic Article Selective expansion of T cells expressing V beta 2 in toxic shock syndrome.
Academic Article Bax does not have to adopt its final form to drive T cell death.
Academic Article Not all CD4+ memory T cells are long lived.
Academic Article Stimulation of B10.BR T cells with superantigenic staphylococcal toxins.
Academic Article CD8 T cell competition for dendritic cells in vivo is an early event in activation.
Academic Article Bcl-xl does not have to bind Bax to protect T cells from death.
Academic Article HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.
Academic Article Identification of a new cell surface glycoprotein with accessory function in murine T cell responses.
Academic Article Germline-encoded recognition of diverse glycolipids by natural killer T cells.
Academic Article The T cell receptors.
Academic Article Apoptosis and the homeostatic control of immune responses.
Academic Article Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.
Academic Article Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses.
Academic Article Baculovirus-infected insect cells expressing peptide-MHC complexes elicit protective antitumor immunity.
Academic Article The toxicity of staphylococcal enterotoxin B in mice is mediated by T cells.
Academic Article Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells.
Academic Article Identification of two major types of age-associated CD8 clonal expansions with highly divergent properties.
Academic Article CD4 memory T cells divide poorly in response to antigen because of their cytokine profile.
Academic Article Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection.
Academic Article CD4 memory T cells: what are they and what can they do?
Academic Article Vaccination of mice with baculovirus-infected insect cells expressing antigenic proteins.
Academic Article Transgenic Bcl-3 slows T cell proliferation.
Academic Article The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity.
Academic Article Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.
Academic Article A conserved CXXC motif in CD3epsilon is critical for T cell development and TCR signaling.
Academic Article Memory CD4 T cells: generation, reactivation and re-assignment.
Academic Article Chromogranin A is an autoantigen in type 1 diabetes.
Academic Article Genetic and hormonal factors in female-biased autoimmunity.
Academic Article Crystal structure of HLA-DP2 and implications for chronic beryllium disease.
Academic Article Reactivity of V beta 17a+ CD8+ T cell hybrids. Analysis using a new CD8+ T cell fusion partner.
Academic Article Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.
Academic Article Immature thymocytes are protected from deletion early in ontogeny.
Academic Article Alpha beta T cell receptor and CD3 transduce different signals in immature T cells. Implications for selection and tolerance.
Academic Article Analysis of V beta 17a expression in new mouse strains bearing the V beta a haplotype.
Academic Article Production and characterization of T cell hybridomas.
Academic Article Genetic markers of the antigen-specific T cell receptor locus.
Academic Article Memory CD4 T cells that express CXCR5 provide accelerated help to B cells.
Academic Article Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers.
Academic Article Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells.
Academic Article T-cell repertoire and thymus.
Academic Article A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers.
Academic Article The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.
Academic Article Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.
Academic Article TCR hypervariable regions expressed by T cells that respond to effective tumor vaccines.
Academic Article Two better cell lines for making hybridomas expressing specific T cell receptors.
Academic Article Influence of the major histocompatibility complex on positive thymic selection of V beta 17a+ T cells.
Academic Article T cell tolerance to self antigens in New Zealand hybrid mice with lupus-like disease.
Academic Article Lower TCR repertoire diversity in Traj18-deficient mice.
Academic Article TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice.
Academic Article Molecular basis for the nonexpression of V beta 17 in some strains of mice.
Academic Article The Ikaros transcription factor regulates responsiveness to IL-12 and expression of IL-2 receptor alpha in mature, activated CD8 T cells.
Academic Article Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence.
Academic Article The role of LFA-1 in class II restricted, antigen-specific T-cell responses.
Academic Article The development of helper T cell precursors in mouse thymus.
Academic Article H-2-linked Ir gene control of VH determinant(s)-specific helper T cells.
Academic Article The T-cell repertoire for antigen and MHC.
Academic Article The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibody.
Academic Article Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex.
Academic Article Remethylation at sites 5' of the murine Lyt-2 gene in association with shutdown of Lyt-2 expression.
Academic Article The T cell receptor.
Academic Article Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen.
Academic Article The T cell and its receptor.
Academic Article T cells can distinguish between allogeneic major histocompatibility complex products on different cell types.
Academic Article The effect of thymus environment on T cell development and tolerance.
Academic Article The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens.
Academic Article T cell tolerance by clonal elimination in the thymus.
Academic Article Both immature and mature T cells mobilize Ca2+ in response to antigen receptor crosslinking.
Academic Article Peptide sequences of T-cell receptor delta and gamma chains are identical to predicted X and gamma proteins.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. IX. Role of accessory molecules in recognition of antigen plus isolated IA.
Academic Article Antigen-specific and nonspecific mediatiors of T cell/B cell cooperation. II. Two helper T cells distinguished by their antigen sensitivities.
Academic Article T cell receptor/MHC interactions in the thymus and the shaping of the T cell repertoire.
Academic Article Antigen-specific and nonspecific mediators of T cell/B cell cooperation. III. Characterization of the nonspecific mediator(s) from different sources.
Academic Article The T cell receptor: its repertoire and role in thymocyte development.
Academic Article Antigen-specific and nonspecific mediators of T cell/B cell cooperation. IV. Development of a model system demonstrating responsiveness of two T cell functions to HGG in vitro.
Academic Article Regulation of the immune response. IV. Antibody-mediated suppression of the immune response to haptens and heterologous erythrocyte antigens in vitro.
Academic Article Regulation of the immune response. V. Antibody-mediated inhibition of T and B cell cooperation in the in vitro response to red cell antigens.
Academic Article Components of the ligand for a Ni++ reactive human T cell clone.
Academic Article Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts.
Academic Article Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity.
Academic Article Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity.
Academic Article The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.
Academic Article A role for T cell helper factors in antibody responses to "T-independent" antigens.
Academic Article Two distinct mechanisms of immune suppression by antibody.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells.
Academic Article Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.
Academic Article Immunoglobulin-like nature of the alpha-chain of a human T-cell antigen/MHC receptor.
Academic Article Mechanisms of antigen processing and presentation.
Academic Article Antigen-specific, major histocompatibility complex-restricted T cell receptors.
Academic Article Primary structure of human T-cell receptor alpha-chain.
Academic Article T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice.
Academic Article Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays.
Academic Article Mouse spleen dendritic cells present soluble antigens to antigen-specific T cell hybridomas.
Academic Article B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor.
Academic Article B cell helper factors. II. Synergy among three helper factors in the response of T cell- and macrophage-depleted B cells.
Academic Article Nonspecific factors in B cell responses.
Academic Article Superantigens: mechanism of T-cell stimulation and role in immune responses.
Academic Article Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B.
Academic Article Lipopolysaccharide interferes with the induction of peripheral T cell death.
Academic Article Cell surface expression of class II MHC proteins bound by a single peptide.
Academic Article Control of Bcl-2 expression by reactive oxygen species.
Academic Article Death and T cells.
Academic Article Control of T cell viability.
Academic Article Fibroblasts can induce thymocyte positive selection in vivo.
Academic Article Comparison of peptides bound to spleen and thymus class II.
Academic Article Unexpected expansions of CD8-bearing cells in old mice.
Academic Article The repertoire of T cells shaped by a single MHC/peptide ligand.
Academic Article Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneity.
Academic Article Thymocytes can become mature T cells without passing through the CD4+ CD8+, double-positive stage.
Academic Article CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo.
Academic Article Characteristics and maintenance of CD8+ T-cell clones found in old mice.
Academic Article Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition.
Academic Article T cells can be activated by peptides that are unrelated in sequence to their selecting peptide.
Academic Article Suppressor T-cell inactivation of a helper T-cell factor.
Academic Article Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes.
Academic Article Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture.
Academic Article Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen.
Academic Article A cell line that can induce thymocyte positive selection.
Academic Article Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.
Academic Article Invariant chain can bind MHC class II at a site other than the peptide binding groove.
Academic Article T-cell survival.
Academic Article Type I interferons keep activated T cells alive.
Academic Article Reactive oxygen species regulate activation-induced T cell apoptosis.
Academic Article An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro.
Academic Article Control of homeostasis of CD8+ memory T cells by opposing cytokines.
Academic Article T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo.
Academic Article Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.
Academic Article Homeostasis of alpha beta TCR+ T cells.
Academic Article T cell tolerance.
Academic Article A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus.
Academic Article CD25+CD4+ T cells contribute to the control of memory CD8+ T cells.
Academic Article Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.
Academic Article Epitope dominance, competition and T cell affinity maturation.
Academic Article Negative selection imparts peptide specificity to the mature T cell repertoire.
Academic Article Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation.
Academic Article A role for clonal inactivation in T cell tolerance to Mls-1a.
Academic Article Homeostatically proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.
Academic Article Bim and Bcl-2 mutually affect the expression of the other in T cells.
Academic Article Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains.
Academic Article The role of H-2-linked genes in helper T cell function. V. I-region control of helper T cell interaction with antigen-presenting macrophages.
Academic Article Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice.
Academic Article Effects of warfarin administration on the immune response of mice.
Academic Article Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation.
Academic Article CD8 T cell clonal expansions & aging: a heterogeneous phenomenon with a common outcome.
Academic Article Superantigens interact with MHC class II molecules outside of the antigen groove.
Academic Article The staphylococcal enterotoxins and their relatives.
Academic Article Demethylated CD8 gene in CD4+ T cells suggests that CD4+ cells develop from CD8+ precursors.
Academic Article Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.
Academic Article T cell allorecognition via molecular mimicry.
Academic Article Evidence that Mls-2 antigens which delete V beta 3+ T cells are controlled by multiple genes.
Academic Article Immune mechanisms of protection: can adjuvants rise to the challenge?
Academic Article Linking genetic susceptibility and T cell activation in beryllium-induced disease.
Academic Article The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice.
Academic Article V beta-specific stimulation of human T cells by staphylococcal toxins.
Academic Article Consequences of self and foreign superantigen interaction with specific V beta elements of the murine TCR alpha beta.
Academic Article Aluminum adjuvants elicit fibrin-dependent extracellular traps in vivo.
Academic Article Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens.
Academic Article The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity.
Academic Article The major histocompatibility complex-restricted antigen receptor on T cells: the genetics of expression of an allotype.
Academic Article Effect of prostaglandin E2 on the gamma-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas.
Academic Article The function of antigen-presenting cells in mice with severe combined immunodeficiency.
Academic Article Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.
Academic Article Peptide vaccines prevent tumor growth by activating T cells that respond to native tumor antigens.
Academic Article Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells. 1990.
Academic Article Molecular targeting of islet autoantigens.
Academic Article Tolerance to self antigens shapes the T-cell repertoire.
Academic Article Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c? B-cell population is important for the development of autoimmunity.
Academic Article T cells and their eons-old obsession with MHC.
Academic Article T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.
Academic Article Ikaros promotes rearrangement of TCR a genes in an Ikaros null thymoma cell line.
Academic Article Recognition of self and altered self by T cells in autoimmunity and allergy.
Academic Article Thymocytes with the predicted properties of pre-T cells.
Academic Article Isotypic exclusion of gamma delta T cell receptors in transgenic mice bearing a rearranged beta-chain gene.
Academic Article Synchronized rearrangement of T-cell gamma and beta chain genes in fetal thymocyte development.
Academic Article T cell receptors in the thymus.
Academic Article Rearrangement of IgH genes in normal thymocyte development.
Academic Article Compartmentalization of MHC class II gene expression in transgenic mice.
Academic Article The T-cell accessory molecule CD4 recognizes a monomorphic determinant on isolated Ia.
Academic Article Involvement of major histocompatibility complex products in tolerance induction in the thymus.
Academic Article T-cell specificity and repertoire.
Academic Article Expression and role of the T cell receptor in early thymocyte differentiation in vitro.
Academic Article Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium.
Academic Article Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?
Academic Article MAIT cell recognition of MR1 on bacterially infected and uninfected cells.
Academic Article Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells.
Academic Article The antigen-specific, major histocompatibility complex-restricted receptor on T cells.
Academic Article L3T4 interacts with class II molecules on target cells.
Academic Article B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells.
Academic Article The T cell repertoire may be biased in favor of MHC recognition.
Academic Article Rearrangement of T-cell receptor beta-chain genes during T-cell development.
Concept Jurkat Cells
Concept Hematopoietic Stem Cells
Concept Lymphocytes
Concept Epithelial Cells
Concept T-Lymphocytes, Cytotoxic
Concept Hybrid Cells
Concept CD8-Positive T-Lymphocytes
Concept T-Lymphocytes, Helper-Inducer
Concept Clone Cells
Concept Th1 Cells
Concept Dendritic Cells
Concept Germ Cells
Concept T-Lymphocytes, Regulatory
Concept Induced Pluripotent Stem Cells
Concept CD4-Positive T-Lymphocytes
Concept Antigen-Presenting Cells
Concept Th2 Cells
Concept B-Lymphocytes
Concept Tumor Cells, Cultured
Concept Antibody-Producing Cells
Concept Bone Marrow Cells
Concept Lymphocytes, Null
Concept Mast Cells
Concept Myeloid Cells
Concept Killer Cells, Natural
Concept Insulin-Secreting Cells
Concept Cells, Cultured
Concept T-Lymphocytes
Concept Natural Killer T-Cells
Academic Article T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance.
Academic Article Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease.
Academic Article Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity.
Academic Article Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.
Academic Article Identification of multiple public TCR repertoires in chronic beryllium disease.
Academic Article Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation.
Academic Article Molecules in medicine mini review: the a? T cell receptor.
Academic Article Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease.
Academic Article Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Academic Article Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
Academic Article Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease.
Academic Article Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects.
Academic Article CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs.
Academic Article A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas.
Academic Article Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation.
Academic Article Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice.
Academic Article Genotype-phenotype relationship in various degrees of arylsulfatase A deficiency.
Academic Article Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR.
Academic Article Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines.
Academic Article Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors.
Academic Article Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.
Academic Article T Cell Production of IFN? in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses.
Academic Article Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
Academic Article B cells expressing the transcription factor T-bet drive lupus-like autoimmunity.
Grant Regulatory Mechanisms in the Immune System
Grant REGULATORY MECHANISMS IN THE IMMUNE SYSTEM
Grant Molecular Mechanisms of MHCII Recognition by CD8 T Cells in HIV Non-Progressor Patients
Academic Article Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Academic Article C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Concept Sf9 Cells
Academic Article How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Academic Article Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules.
Academic Article Age-associated B Cells Appear in Patients with Granulomatous Lung Diseases.
Academic Article Tolerance induction in memory CD4 T cells is partial and reversible.
Academic Article Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation.
Academic Article A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice.
Academic Article Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Academic Article Beryllium-specific CD4+ T cells induced by chemokine neoantigens perpetuate inflammation.
Academic Article Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes.
Academic Article Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Academic Article Generation of functional human thymic cells from induced pluripotent stem cells.

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