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Search Results to Christopher Silliman

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Silliman, Christopher

One or more keywords matched the following items that are connected to Silliman, Christopher

Item Type	Name
Concept	Plasminogen
Concept	Plasminogen Activator Inhibitor 1
Concept	Tissue Plasminogen Activator
Academic Article	Hemolysis exacerbates hyperfibrinolysis, whereas platelolysis shuts down fibrinolysis: evolving concepts of the spectrum of fibrinolysis in response to severe injury.
Academic Article	Plasma is the physiologic buffer of tissue plasminogen activator-mediated fibrinolysis: rationale for plasma-first resuscitation after life-threatening hemorrhage.
Academic Article	Postinjury fibrinolysis shutdown: Rationale for selective tranexamic acid.
Academic Article	Fibrinolysis shutdown phenotype masks changes in rodent coagulation in tissue injury versus hemorrhagic shock.
Academic Article	a-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2.
Academic Article	Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients.
Academic Article	Overwhelming tPA release, not PAI-1 degradation, is responsible for hyperfibrinolysis in severely injured trauma patients.
Academic Article	Rationale for the selective administration of tranexamic acid to inhibit fibrinolysis in the severely injured patient.
Academic Article	Freeze-dried plasma enhances clot formation and inhibits fibrinolysis in the presence of tissue plasminogen activator similar to pooled liquid plasma.
Academic Article	Viscoelastic Tissue Plasminogen Activator Challenge Predicts Massive Transfusion in 15 Minutes.
Academic Article	Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin.
Academic Article	14-Day thawed plasma retains clot enhancing properties and inhibits tPA-induced fibrinolysis.
Academic Article	Thrombin Provokes Degranulation of Platelet a-Granules Leading to the Release of Active Plasminogen Activator Inhibitor-1 (PAI-1).
Academic Article	Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator.
Academic Article	Systemic hyperfibrinolysis after trauma: a pilot study of targeted proteomic analysis of superposed mechanisms in patient plasma.
Academic Article	Thrombin stimulates increased plasminogen activator inhibitor-1 release from liver compared to lung endothelium.
Academic Article	28-day thawed plasma maintains a2 -antiplasmin levels and inhibits tPA-induced fibrinolysis.
Academic Article	Effects of Blood Components and Whole Blood in a Model of Severe Trauma-Induced Coagulopathy.
Academic Article	The a-globin chain of hemoglobin potentiates tissue plasminogen activator induced hyperfibrinolysis in vitro.
Academic Article	Beyond uterine atony: characterizing postpartum hemorrhage coagulopathy.

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Plasminogen