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Search Results to Christopher Silliman

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Silliman, Christopher

One or more keywords matched the following items that are connected to Silliman, Christopher

Item Type	Name
Academic Article	Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase.
Academic Article	Stored blood components contain agents that prime the neutrophil NADPH oxidase through the platelet-activating-factor receptor.
Academic Article	Interleukin-6 stimulates neutrophil production of platelet-activating factor.
Academic Article	Neutrophil priming and activation in the pathogenesis of postinjury multiple organ failure.
Academic Article	Sequential systemic platelet-activating factor and interleukin 8 primes neutrophils in patients with trauma at risk of multiple organ failure.
Academic Article	The association of biologically active lipids with the development of transfusion-related acute lung injury: a retrospective study.
Academic Article	Beta-adrenergic stimulation down-regulates neutrophil priming for superoxide generation, but not elastase release.
Academic Article	Prostaglandin E1 attenuates cytotoxic mechanisms of primed neutrophils.
Academic Article	Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model.
Academic Article	Hypertonic saline activates lipid-primed human neutrophils for enhanced elastase release.
Academic Article	Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophils.
Academic Article	Interleukin-6 augments neutrophil cytotoxic potential via selective enhancement of elastase release.
Academic Article	Receptor-mediated calcium entry is required for maximal effects of platelet activating factor primed responses in human neutrophils.
Academic Article	Clinically relevant concentrations of ethanol attenuate primed neutrophil bactericidal activity.
Academic Article	Circulating postinjury neutrophils are primed for the release of proinflammatory cytokines.
Academic Article	Posthemorrhagic shock mesenteric lymph primes circulating neutrophils and provokes lung injury.
Academic Article	Disparities in the respiratory burst between human and rat neutrophils.
Academic Article	Stored red blood cells selectively activate human neutrophils to release IL-8 and secretory PLA2.
Academic Article	Hypertonic saline resuscitation abrogates neutrophil priming by mesenteric lymph.
Academic Article	Maximal human neutrophil priming for superoxide production and elastase release requires p38 mitogen-activated protein kinase activation.
Academic Article	Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability.
Academic Article	Extracellular signal-related kinase 1/2 and p38 mitogen-activated protein kinase pathways serve opposite roles in neutrophil cytotoxicity.
Academic Article	Hypertonic saline inhibits neutrophil (PMN) priming via attenuation of p38 MAPK signaling.
Academic Article	The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential.
Academic Article	Blood transfusion and the two-insult model of post-injury multiple organ failure.
Academic Article	Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge.
Academic Article	Mesenteric lymph is responsible for post-hemorrhagic shock systemic neutrophil priming.
Academic Article	ICAM-1-CD18 interaction mediates neutrophil cytotoxicity through protease release.
Academic Article	Post-hemorrhagic shock mesenteric lymph activates human pulmonary microvascular endothelium for in vitro neutrophil-mediated injury: the role of intercellular adhesion molecule-1.
Academic Article	Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium.
Academic Article	In vivo treatment with granulocyte colony-stimulating factor results in divergent effects on neutrophil functions measured in vitro.
Academic Article	Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.
Academic Article	The abdominal compartment syndrome as a second insult during systemic neutrophil priming provokes multiple organ injury.
Academic Article	Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils.
Academic Article	Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.
Academic Article	The two-event model of transfusion-related acute lung injury.
Academic Article	Arachidonic acid in postshock mesenteric lymph induces pulmonary synthesis of leukotriene B4.
Academic Article	The systemic inflammatory response syndrome induces functional changes and relative hyporesponsiveness in neutrophils.
Academic Article	Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils.
Academic Article	Gender-specific transfusion affects tumor-associated neutrophil: macrophage ratios in murine pancreatic adenocarcinoma.
Academic Article	Proteomic analysis of human mesenteric lymph.
Academic Article	A two-event in vitro model of acute chest syndrome: the role of secretory phospholipase A2 and neutrophils.
Academic Article	Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase.
Academic Article	The pro-inflammatory effects of platelet contamination in plasma and mitigation strategies for avoidance.
Academic Article	Therapeutic options for transfusion related acute lung injury; the potential of the G2A receptor.
Academic Article	Nebulized hypertonic saline attenuates acute lung injury following trauma and hemorrhagic shock via inhibition of matrix metalloproteinase-13.
Academic Article	Hyperosmolarity attenuates TNF-a-mediated proinflammatory activation of human pulmonary microvascular endothelial cells.
Academic Article	Compounds biologically similar to platelet activating factor are present in stored blood components.
Academic Article	Platelets and neutrophils from healthy term neonates exhibit increased levels of immunoglobulins.
Academic Article	Nitric oxide attenuates platelet-activating factor priming for elastase release in human neutrophils via a cyclic guanosine monophosphate-dependent pathway.
Academic Article	Systemic neutrophil priming by lipid mediators in post-shock mesenteric lymph exists across species.
Academic Article	Secretory phospholipase A2 cleavage of intravasated bone marrow primes human neutrophils.
Academic Article	Primed neutrophils require phosphatidic acid for maximal receptor-activated elastase release.
Academic Article	New mechanisms by which secretory phospholipase A2 stimulates neutrophils to provoke the release of cytotoxic agents.
Academic Article	Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation.
Academic Article	Postinjury suppression of human neutrophil cytokine production results from the stabilization of inhibitory kappaB.
Academic Article	Neutrophils are primed for cytotoxicity and resist apoptosis in injured patients at risk for multiple organ failure.
Academic Article	Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation.
Academic Article	Hypertonic saline attenuation of polymorphonuclear neutrophil cytotoxicity: timing is everything.
Academic Article	Transfusion-related acute lung injury secondary to biologically active mediators.
Academic Article	Plasma from aged stored red blood cells delays neutrophil apoptosis and primes for cytotoxicity: abrogation by poststorage washing but not prestorage leukoreduction.
Academic Article	Resuscitation with a blood substitute abrogates pathologic postinjury neutrophil cytotoxic function.
Academic Article	Hyperosmolarity abrogates neutrophil cytotoxicity provoked by post-shock mesenteric lymph.
Academic Article	Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Academic Article	Presence of the M-type sPLA(2) receptor on neutrophils and its role in elastase release and adhesion.
Academic Article	Neutrophil apoptosis is delayed by trauma patients' plasma via a mechanism involving proinflammatory phospholipids and protein kinase C.
Academic Article	Transfusion-induced leukocyte IL-8 gene expression is avoided by the use of human polymerized hemoglobin.
Academic Article	Using a miniaturized circuit and an asanguineous prime to reduce neutrophil-mediated organ dysfunction following infant cardiopulmonary bypass.
Academic Article	The role of endothelial activation in the pathogenesis of transfusion-related acute lung injury.
Academic Article	Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model.
Academic Article	Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.
Academic Article	The role of neutrophils in the pathogenesis of transfusion-related acute lung injury.
Academic Article	Cardiopulmonary bypass induces enduring alterations to host neutrophil physiology: a single-center longitudinal observational study.
Academic Article	Platelet-activating factor-mediated endosome formation causes membrane translocation of p67phox and p40phox that requires recruitment and activation of p38 MAPK, Rab5a, and phosphatidylinositol 3-kinase in human neutrophils.
Academic Article	A novel in vivo ovine model of transfusion-related acute lung injury (TRALI).
Academic Article	Lysophosphatidylcholines activate G2A inducing G(ai)?1-/G(aq/)11- Ca?(+) flux, G(??)-Hck activation and clathrin/?-arrestin-1/GRK6 recruitment in PMNs.
Academic Article	Amantadine inhibits platelet-activating factor induced clathrin-mediated endocytosis in human neutrophils.
Academic Article	Leukotriene b4 and its metabolites prime the neutrophil oxidase and induce proinflammatory activation of human pulmonary microvascular endothelial cells.
Academic Article	Cross-transfusion of postshock mesenteric lymph provokes acute lung injury.
Academic Article	Transfusion-related acute lung injury: advances in understanding the role of proinflammatory mediators in its genesis.
Concept	Neutrophils
Concept	Neutrophil Activation
Concept	Neutrophil Infiltration
Academic Article	Antibodies to the HLA-A2 antigen prime neutrophils and serve as the second event in an in vitro model of transfusion-related acute lung injury.
Academic Article	Dynamic changes in rat mesenteric lymph proteins following trauma using label-free mass spectrometry.
Academic Article	The pro-inflammatory potential of microparticles in red blood cell units.
Academic Article	a-Enolase Causes Proinflammatory Activation of Pulmonary Microvascular Endothelial Cells and Primes Neutrophils Through Plasmin Activation of Protease-Activated Receptor 2.
Academic Article	Neutrophil function in children following allogeneic hematopoietic stem cell transplant.
Academic Article	LysoPCs induce Hck- and PKCd-mediated activation of PKC? causing p47phox phosphorylation and membrane translocation in neutrophils.
Academic Article	Antibodies to major histocompatibility complex class II antigens directly prime neutrophils and cause acute lung injury in a two-event in vivo rat model.
Grant	Lyso-PCs activate PMNs and endothelium via PKC
Academic Article	Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin.
Academic Article	Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia.
Academic Article	A comparison of different methods of red blood cell leukoreduction and additive solutions on the accumulation of neutrophil-priming activity during storage.
Academic Article	Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS.
Academic Article	A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player.

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