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Search Results to James Veblen DeGregori

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One or more keywords matched the following items that are connected to DeGregori, James

Item TypeName
Academic Article Selective disruption of genes expressed in totipotent embryonal stem cells.
Academic Article Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene.
Academic Article Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice.
Academic Article Impaired DNA replication within progenitor cell pools promotes leukemogenesis.
Academic Article Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations.
Academic Article Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.
Academic Article Irradiation selects for p53-deficient hematopoietic progenitors.
Academic Article Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis.
Academic Article Prolactin stimulates activation of c-jun N-terminal kinase (JNK).
Academic Article Irradiation alters selection for oncogenic mutations in hematopoietic progenitors.
Academic Article Relative fitness of hematopoietic progenitors influences leukemia progression.
Academic Article Evolved tumor suppression: why are we so good at not getting cancer?
Concept Hematopoietic Stem Cells
Concept Neoplastic Stem Cells
Concept Hematopoietic Stem Cell Transplantation
Concept Multipotent Stem Cells
Concept Stem Cells
Concept Stem Cell Niche
Academic Article Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes.
Academic Article Contrasting roles for C/EBPa and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects.
Academic Article Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations.
Academic Article A Critical Examination of the "Bad Luck" Explanation of Cancer Risk.
Academic Article Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
Academic Article Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia.
Academic Article The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection.
Grant Nrf2-mediated impaired hematopoietic stem cell fitness following irradiation
Grant Poor competition in hematopoietic stem/progenitor pools favors tumorigenesis
Grant Aging-associated alterations in adaptive landscapes and the evolution of leukemia
Academic Article Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.
Academic Article SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program.
Academic Article Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.
Academic Article Elimination of unfit cells in young and ageing skin.
Academic Article A generalized theory of age-dependent carcinogenesis.
Academic Article Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.
Grant Understanding and circumventing aging-dependent changes in the bone marrow microenvironment that promote leukemogenesis
Academic Article Molecular Biology and Evolution of Cancer: From Discovery to Action.
Grant Determining how aging-associated changes in the microenvironment contribute to leukemogenesis
Grant Aged tissue environments as drivers of oncogenic adaptation in hematopoiesis
Academic Article Of mice, genes and aging.
Academic Article Aging, inflammation, and HSC.
Academic Article A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution.
Academic Article Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.
Academic Article PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress.
Academic Article Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors.
Academic Article Cancer stem cells in the gut have a bad influence on neighbouring cells.
Grant Impact of aging and clonal hematopoiesis on epigenetic heterogeneity, evolvability, and leukemogenesis
Academic Article Dnmt3a-Mutant Hematopoietic Stem Cell Rewire IFN? Signaling to Gain Clonal Advantage.

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