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Search Results to Douglas R Seals

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Item TypeName
Academic Article Effect of endurance exercise training on ventilatory function in older individuals.
Academic Article The effect of left ventricular systolic function on maximal aerobic exercise capacity in asymptomatic patients with coronary artery disease.
Academic Article Effects of high-intensity strength training on cardiovascular function.
Academic Article Effects of endurance training on glucose tolerance and plasma lipid levels in older men and women.
Academic Article Endurance training in older men and women. I. Cardiovascular responses to exercise.
Academic Article Endurance training in older men and women II. Blood lactate response to submaximal exercise.
Academic Article Cardiovascular, plasma norepinephrine, and thermal adjustments to prolonged exercise in young and older healthy humans.
Academic Article Hemostatic, metabolic, and androgenic risk factors for coronary heart disease in physically active and less active postmenopausal women.
Academic Article Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors.
Academic Article Maximal aerobic capacity and total blood volume in highly trained middle-aged and older female endurance athletes.
Academic Article Endurance exercise training is associated with elevated basal sympathetic nerve activity in healthy older humans.
Academic Article Effects of aging on epinephrine secretion and regional release of epinephrine from the human heart.
Academic Article Active forearm blood flow adjustments to handgrip exercise in young and older healthy men.
Academic Article Exercise and aging: autonomic control of the circulation.
Academic Article Total blood volume in healthy young and older men.
Academic Article Postexercise hypotension. Key features, mechanisms, and clinical significance.
Academic Article Adiposity and regional body fat distribution in physically active young and middle-aged women.
Academic Article Elevated heart rate variability in physically active postmenopausal women: a cardioprotective effect?
Academic Article Influence of exercise training on heart rate variability in post-menopausal women with elevated arterial blood pressure.
Academic Article The effect of exercise training on human hypertension: a review.
Academic Article Sympathoadrenal-circulatory regulation of arterial pressure during orthostatic stress in young and older men.
Academic Article Age and gender interactions in physiological functional capacity: insight from swimming performance.
Academic Article Relations of total and abdominal adiposity to muscle sympathetic nerve activity in healthy older males.
Academic Article Greater rate of decline in maximal aerobic capacity with age in physically active vs. sedentary healthy women.
Academic Article Augmented forearm vasoconstriction during dynamic exercise in healthy older men.
Academic Article Effect of regular aerobic exercise on elevated blood pressure in postmenopausal women.
Academic Article Physical activity status and adverse age-related differences in coagulation and fibrinolytic factors in women.
Academic Article Age-related increase in muscle sympathetic nerve activity is associated with abdominal adiposity.
Academic Article Plasma fibrinogen levels in healthy postmenopausal women: physical activity and hormone replacement status.
Academic Article Regular exercise and the age-related decline in resting metabolic rate in women.
Academic Article Augmented cardiopulmonary and integrative sympathetic baroreflexes but attenuated peripheral vasoconstriction with age.
Academic Article Reproducibility of a semiautomated acetylene rebreathing technique for measuring cardiac output in humans at rest.
Academic Article Arterial stiffness and hormone replacement use in healthy postmenopausal women.
Academic Article Aging effects on human sympathetic neuronal function.
Academic Article Smaller differences in total and regional adiposity with age in women who regularly perform endurance exercise.
Academic Article Neural mechanisms in human obesity-related hypertension.
Academic Article Enhanced left ventricular performance in endurance trained older men.
Academic Article Lack of age-associated elevations in 24-h systolic and pulse pressures in women who exercise regularly.
Academic Article Age and gender influence muscle sympathetic nerve activity at rest in healthy humans.
Academic Article Aging, habitual exercise, and dynamic arterial compliance.
Academic Article Relation of leptin and insulin to adiposity-associated elevations in sympathetic activity with age in humans.
Academic Article Age-related declines in knee extensor strength and physical performance in healthy Hispanic and Caucasian women.
Academic Article Carotid artery wall hypertrophy with age is related to local systolic blood pressure in healthy men.
Academic Article Age-related decreases in basal limb blood flow in humans: time course, determinants and habitual exercise effects.
Academic Article Tonic sympathetic support of metabolic rate is attenuated with age, sedentary lifestyle, and female sex in healthy adults.
Academic Article Pharmacologic versus flow-mediated assessments of peripheral vascular endothelial vasodilatory function in humans.
Academic Article Altered autonomic support of arterial blood pressure with age in healthy men.
Academic Article Regular endurance exercise induces expansive arterial remodelling in the trained limbs of healthy men.
Academic Article Blood pressure risks factors in healthy postmenopausal women: physical activity and hormone replacement.
Academic Article Arterial intima-media thickness: site-specific associations with HRT and habitual exercise.
Academic Article Changes in maximal aerobic capacity with age in endurance-trained women: 7-yr follow-up.
Academic Article Elevated levels of circulating cell adhesion molecules in uncomplicated essential hypertension.
Academic Article Leptin in human plasma is derived in part from the brain, and cleared by the kidneys.
Academic Article Effects of training on systolic time intervals at rest and during isometric exercise in men and women 61 to 64 years old.
Academic Article Lactate threshold and distance-running performance in young and older endurance athletes.
Academic Article A hemodynamic comparison of young and older endurance athletes during exercise.
Academic Article Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance.
Academic Article Use of acetylene breathing to determine cardiac output in young and older adults.
Academic Article Role of central circulatory factors in the fat-free mass-maximal aerobic capacity relation across age.
Academic Article Influence of body fatness on the coronary risk profile of physically active postmenopausal women.
Academic Article Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women.
Academic Article Baroreflex buffering is reduced with age in healthy men.
Academic Article Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men.
Academic Article Hemodynamic sequelae of age-related increases in arterial stiffness in healthy women.
Academic Article Influence of adiposity on tonic sympathetic support of resting metabolism in healthy adults.
Academic Article Cardiopulmonary baroreflex inhibition of sympathetic nerve activity is preserved with age in healthy humans.
Academic Article Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing.
Academic Article Ascorbic acid does not affect large elastic artery compliance or central blood pressure in young and older men.
Academic Article Oxidative stress does not modulate metabolic rate or skeletal muscle sympathetic activity with primary aging in adult humans.
Academic Article Left ventricular structure and diastolic function with human ageing. Relation to habitual exercise and arterial stiffness.
Academic Article Ascorbic acid does not affect the age-associated reduction in maximal cardiac output and oxygen consumption in healthy adults.
Academic Article Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension.
Academic Article Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging.
Academic Article Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men.
Academic Article Role of sympathetic neural activation in age- and habitual exercise-related differences in the thermic effect of food.
Academic Article Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults.
Academic Article Thermogenic responsiveness to nonspecific beta-adrenergic stimulation is not related to genetic variation in codon 16 of the beta2-adrenergic receptor.
Academic Article Decline in large elastic artery compliance with age: a therapeutic target for habitual exercise.
Academic Article Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression.
Academic Article Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress.
Academic Article Thermic effect of food and beta-adrenergic thermogenic responsiveness in habitually exercising and sedentary healthy adult humans.
Academic Article Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults.
Academic Article Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans.
Academic Article Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans.
Academic Article Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase.
Academic Article Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults.
Academic Article Limb blood flow and vascular conductance are reduced with age in healthy humans: relation to elevations in sympathetic nerve activity and declines in oxygen demand.
Academic Article Role of NFkappaB in age-related vascular endothelial dysfunction in humans.
Academic Article Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults.
Academic Article Life-long caloric restriction elicits pronounced protection of the aged myocardium: a role for AMPK.
Academic Article Age-associated arterial wall thickening is related to elevations in sympathetic activity in healthy humans.
Academic Article 25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults.
Academic Article Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men.
Academic Article Regular aerobic exercise modulates age-associated declines in cardiovagal baroreflex sensitivity in healthy men.
Academic Article Total and regional body composition across age in healthy Hispanic and white women of similar socioeconomic status.
Academic Article Age-predicted maximal heart rate revisited.
Academic Article SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans.
Academic Article Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress.
Academic Article Hysterectomy is associated with large artery stiffening in estrogen-deficient postmenopausal women.
Academic Article Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged/older adults with moderately elevated systolic blood pressure.
Academic Article Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults.
Academic Article Pulmonary function in young and older athletes and untrained men.
Academic Article Mechanism of contrasting pressor responses to static and dynamic exercise: new insights from direct intraneural recordings of sympathetic nerve activity in humans.
Academic Article Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men.
Academic Article Glucose tolerance in young and older athletes and sedentary men.
Academic Article Elevated high-density lipoprotein cholesterol levels in older endurance athletes.
Academic Article Physiological determinants of 10-km performance in highly trained female runners of different ages.
Academic Article Muscle sympathetic nerve activity during postural change in healthy young and older adults.
Academic Article High energy flux mediates the tonically augmented beta-adrenergic support of resting metabolic rate in habitually exercising older adults.
Academic Article Lesser vagal withdrawal during isometric exercise with age.
Academic Article Age-related declines in maximal aerobic capacity in regularly exercising vs. sedentary women: a meta-analysis.
Academic Article Absence of age-related decline in total blood volume in physically active females.
Academic Article Influence of age on the sympathetic neural adjustments to alterations in systemic oxygen levels in humans.
Academic Article Sympathoadrenal-circulatory regulation during sustained isometric exercise in young and older men.
Academic Article Physically active women demonstrate less adverse age-related changes in plasma lipids and lipoproteins.
Academic Article Ascorbic acid selectively improves large elastic artery compliance in postmenopausal women.
Academic Article Aortic input impedance increases with age in healthy men and women.
Academic Article Absence of age-related increase in central arterial stiffness in physically active women.
Academic Article Regular walking increases peak limb vasodilatory capacity of older hypertensive humans: implications for arterial structure.
Academic Article Influence of age on arterial baroreflex inhibition of sympathetic nerve activity in healthy adult humans.
Academic Article Elevated heart rate variability in physically active young and older adult women.
Academic Article Xanthine oxidase does not contribute to impaired peripheral conduit artery endothelium-dependent dilatation with ageing.
Academic Article The 'adrenaline hypothesis' of hypertension revisited: evidence for adrenaline release from the heart of patients with essential hypertension.
Academic Article Habitual aerobic exercise is associated with smaller femoral artery intima-media thickness with age in healthy men and women.
Academic Article Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men.
Academic Article Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress.
Academic Article Basal leg blood flow in healthy women is related to age and hormone replacement therapy status.
Academic Article Invited Review: Dynamic exercise performance in Masters athletes: insight into the effects of primary human aging on physiological functional capacity.
Academic Article Chronic sympathetic activation: consequence and cause of age-associated obesity?
Academic Article Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men.
Academic Article Effect of regular exercise on 24-hour arterial pressure in older hypertensive humans.
Academic Article Thermogenic responsiveness to beta-adrenergic stimulation is augmented in exercising versus sedentary adults: role of oxidative stress.
Academic Article Endurance exercise performance in Masters athletes: age-associated changes and underlying physiological mechanisms.
Academic Article Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate.
Academic Article Oxidative stress contributes to chronic leg vasoconstriction in estrogen-deficient postmenopausal women.
Academic Article Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans.
Academic Article Vascular endothelial estrogen receptor alpha is modulated by estrogen status and related to endothelial function and endothelial nitric oxide synthase in healthy women.
Academic Article Low dietary sodium intake is associated with enhanced vascular endothelial function in middle-aged and older adults with elevated systolic blood pressure.
Academic Article Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB.
Academic Article Increased thermogenic responsiveness to intravenous beta-adrenergic stimulation in habitually exercising humans is not related to skeletal muscle beta2-adrenergic receptor density.
Academic Article High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men.
Academic Article Modulation of vascular endothelial function by low-density lipoprotein cholesterol with aging: influence of habitual exercise.
Academic Article Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins.
Academic Article Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity.
Academic Article Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise.
Academic Article Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women.
Academic Article Influence of physical training on heart rate variability and baroreflex circulatory control.
Academic Article Vascular endothelial function is not related to serum uric acid in healthy adults.
Academic Article Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging.
Academic Article Resistive training can reduce coronary risk factors without altering VO2max or percent body fat.
Academic Article Glucose tolerance and lipid-lipoprotein levels in middle-aged powerlifters.
Academic Article Replicative aging induces endothelial to mesenchymal transition in human aortic endothelial cells: potential role of inflammation.
Academic Article Translational evidence that impaired autophagy contributes to arterial ageing.
Academic Article Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study.
Academic Article Vascular smooth muscle responsiveness to nitric oxide is reduced in healthy adults with increased adiposity.
Academic Article Metabolic responses to exercise in young and older athletes and sedentary men.
Concept Aged, 80 and over
Concept Aged
Concept Middle Aged
Academic Article Aortic pulse wave velocity and reflecting distance estimation from peripheral waveforms in humans: detection of age- and exercise training-related differences.
Academic Article Dietary sodium restriction and association with urinary marinobufagenin, blood pressure, and aortic stiffness.
Academic Article Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice.
Academic Article Activation of the unfolded protein response in vascular endothelial cells of nondiabetic obese adults.
Academic Article Essential role of estrogen for improvements in vascular endothelial function with endurance exercise in postmenopausal women.
Academic Article Vascular endothelial function and oxidative stress are related to dietary niacin intake among healthy middle-aged and older adults.
Academic Article Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor ?B.
Academic Article Effect of dietary sodium restriction on human urinary metabolomic profiles.
Academic Article Reduced large elastic artery stiffness with regular aerobic exercise in middle-aged and older adults: potential role of suppressed nuclear factor ? B signalling.
Academic Article Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults.
Academic Article Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults.
Academic Article Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity.
Academic Article Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults.
Academic Article Estimated aortic stiffness is independently associated with cardiac baroreflex sensitivity in humans: role of ageing and habitual endurance exercise.
Academic Article Comparative Approaches to Understanding the Relation Between Aging and Physical Function.
Academic Article Habitual aerobic exercise does not protect against micro- or macrovascular endothelial dysfunction in healthy estrogen-deficient postmenopausal women.
Academic Article Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress.
Academic Article Reductions in central arterial compliance with age are related to sympathetic vasoconstrictor nerve activity in healthy men.
Academic Article Vascular Function and Uric Acid-Lowering in Stage 3 CKD.
Grant Translational Studies of Interleukin-37, a Novel Anti-inflammatory Cytokine, for Prevention and Treatment of Inflamm-aging and Age-Associated Physiological Dysfunction
Grant Weight Loss, Inflammation, and Vascular Endothelial Function in Older Adults
Grant Clinical Translation of Curcumin Therapy to Treat Arterial Aging
Grant Human Aging and B-adrenergic Modulation of Thermogenesis
Grant HYPERTENSION IN THE ELDERLY--EFFECTS OF EXERCISE
Grant Nitrite Supplementation for Improving Physiological Function in Older Adults
Grant Mechanisms for Reduced Limb Perfusion with Human Aging
Grant MitoQ Supplementation for Improving Vascular Endothelial Function in Older Adults
Grant Human Aging, Exercise & FMD: Translational Physiology
Grant Clinical Translation of Nitrite Therapy to Treat Arterial Aging in Humans
Grant AEROBIC CAPACITY AND STRENGTH WITH AGE IN HISPANIC WOMEN
Grant Reduced Inflammatory Suppression of EDD with Habitual Exercise in Older Adults
Academic Article Cholecalciferol, Calcitriol, and Vascular Function in CKD: A Randomized, Double-Blind Trial.
Academic Article Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function.
Academic Article Strategies for Achieving Healthy Vascular Aging.
Academic Article Chronic?nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults.
Academic Article Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults.
Academic Article Amino acid and lipid associated plasma metabolomic patterns are related to healthspan indicators with ageing.
Academic Article Curcumin supplementation and motor-cognitive function in healthy middle-aged and older adults.
Academic Article Habitual aerobic exercise and circulating proteomic patterns in healthy adults: relation to indicators of healthspan.
Grant Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in middle-aged and older adults
Academic Article Apocynin and Tempol ameliorate dietary sodium-induced declines in cutaneous microvascular function in salt-resistant humans.
Academic Article Time-efficient physical training for enhancing cardiovascular function in midlife and older adults: promise and current research gaps.
Academic Article The plasma metabolome as a predictor of biological aging in humans.
Academic Article Impact of Red Beetroot Juice on Vascular Endothelial Function and Cardiometabolic Responses to a High-Fat Meal in Middle-Aged/Older Adults with Overweight and Obesity: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.
Academic Article Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults.
Academic Article Effects of resveratrol or estradiol on postexercise endothelial function in estrogen-deficient postmenopausal women.
Academic Article Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans.
Academic Article Dietary sodium restriction decreases urinary NGAL in older adults with moderately elevated systolic blood pressure free from chronic kidney disease.
Academic Article Vascular Endothelial Function in Midlife/Older Adults Classified According to 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines.
Academic Article Novel CPET Reference Values in Healthy Adults: Associations with Physical Activity.
Academic Article Healthy Aging Interventions Reduce Repetitive Element Transcripts.
Academic Article Inorganic Nitrite Supplementation Improves Endothelial Function With Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress.
Academic Article Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans.
Academic Article Time-Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above-Normal Blood Pressure.
Academic Article Time-efficient, high-resistance inspiratory muscle strength training for cardiovascular aging.
Academic Article Six Months of Inspiratory Muscle Training to Lower Blood Pressure and Improve Endothelial Function in Middle-Aged and Older Adults With Above-Normal Blood Pressure and Obstructive Sleep Apnea: Protocol for the CHART Clinical Trial.
Academic Article Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs.
Academic Article Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes.
Academic Article Cerebrovascular pulsatility index is higher in chronic kidney disease.
Academic Article A multi-trial, retrospective analysis of the antihypertensive effects of high-resistance, low-volume inspiratory muscle strength training.
Academic Article Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin.
Academic Article Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions.
Academic Article Neurovascular and hemodynamic responses to mental stress and exercise in severe COVID-19 survivors.
Academic Article Chronic mitochondria antioxidant treatment in older adults alters the circulating milieu to improve endothelial cell function and mitochondrial oxidative stress.
Academic Article Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns.
Academic Article Time-efficient, high-resistance inspiratory muscle strength training increases cerebrovascular reactivity in midlife and older adults.
Academic Article NAD+-boosting compounds enhance nitric oxide production and prevent oxidative stress in endothelial cells exposed to plasma from patients with COVID-19.
Academic Article Time-Efficient, High-Resistance Inspiratory Muscle Strength Training Increases Exercise Tolerance in Midlife and Older Adults.
Academic Article Effects of regular exercise on vascular function with aging: Does sex matter?

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