Item Type | Name |
Academic Article
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Decline in incidence of medulloblastoma in children.
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Academic Article
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Maternal diet and primitive neuroectodermal brain tumors in children.
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Academic Article
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Variation in survival of children with cancer within a region of the United Kingdom.
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Academic Article
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Magnetic resonance imaging and magnetic resonance angiography in long term survivors of acute lymphoblastic leukemia treated with cranial irradiation.
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Academic Article
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Radon in Devon and Cornwall and paediatric malignancies.
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Academic Article
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Intracranial ependymomas: analysis of prognostic factors in a population-based series.
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Academic Article
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Second-look surgery for incompletely resected fourth ventricle ependymomas: technical case report.
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Academic Article
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Chemotherapy for spinal cord astrocytoma.
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Academic Article
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Intracranial large vessel vasculopathy and anaplastic meningioma 19 years after cranial irradiation for acute lymphoblastic leukaemia.
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Academic Article
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Ki-67 immunolabelling index is a prognostic indicator in childhood posterior fossa ependymomas.
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Academic Article
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Adenovirus mediated gene therapy in a glioblastoma vaccine model; specific antitumor immunity and abrogation of immunosuppression.
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Academic Article
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Ependymomas in children.
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Academic Article
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Childhood malignancies in the south-west region of England, 1976-1985.
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Academic Article
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Pattern of recurrence in children with midline posterior fossa malignant neoplasms.
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Academic Article
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Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines.
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Academic Article
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Cystic metastatic cerebral neuroblastoma.
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Academic Article
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Experience with tamoxifen/etoposide in the treatment of a child with myxopapillary ependymoma.
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Academic Article
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Radon exposure and incidence of paediatric malignancies.
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Academic Article
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Rhabdoid glioblastoma.
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Academic Article
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Congenital malignant rhabdoid tumour of the gum margin.
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Academic Article
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Brain stem glioma in a child: false diagnosis of radiation necrosis with FDG PET.
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Academic Article
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Atypical teratoid/rhabdoid tumor of the central nervous system in children: an atypical series and review.
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Academic Article
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Intracranial germ cell tumors: a single institution experience and review of the literature.
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Academic Article
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Cord blood transplant in childhood ALL.
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Academic Article
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A study of sequential high dose cyclophosphamide and high dose carboplatin with peripheral stem-cell rescue in resistant or recurrent pediatric brain tumors.
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Academic Article
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Health status in 52 long-term survivors of pediatric brain tumors.
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Academic Article
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Midpoint CD34 measurement as a predictor of PBPC product yield in pediatric patients undergoing high-dose chemotherapy.
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Academic Article
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Predicting which children are at risk for ependymoma relapse.
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Academic Article
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MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
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Academic Article
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Molecular array analyses of 51 pediatric tumors shows overlap between malignant intracranial ectomesenchymoma and MPNST but not medulloblastoma or atypical teratoid rhabdoid tumor.
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Academic Article
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Unique molecular characteristics of radiation-induced glioblastoma.
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Academic Article
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Claudin 6 is a positive marker for atypical teratoid/rhabdoid tumors.
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Academic Article
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Unique molecular characteristics of pediatric myxopapillary ependymoma.
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Academic Article
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Bevacizumab as therapy for radiation necrosis in four children with pontine gliomas.
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Academic Article
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Pontine gliomas.
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Academic Article
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Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.
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Academic Article
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Creative arts therapy improves quality of life for pediatric brain tumor patients receiving outpatient chemotherapy.
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Academic Article
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Survey of MicroRNA expression in pediatric brain tumors.
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Academic Article
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Memory deficits in patients with pediatric CNS germ cell tumors.
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Academic Article
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Multinodular leptomeningeal metastases from ETANTR contain both small blue cell and maturing neuropil elements.
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Academic Article
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Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells.
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Academic Article
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Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.
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Academic Article
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Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry.
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Academic Article
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Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.
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Academic Article
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Children's Oncology Group's 2013 blueprint for research: central nervous system tumors.
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Academic Article
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Development of an in-home standardized end-of-life treatment program for pediatric patients dying of brain tumors.
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Academic Article
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Epithelioid GBMs show a high percentage of BRAF V600E mutation.
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Academic Article
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Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.
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Academic Article
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Immunomodulatory effects of human neuroblastoma cells transduced with a retroviral vector encoding interleukin-2.
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Academic Article
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Measurement of tamoxifen-induced apoptosis in glioblastoma by cytometric bead analysis of active caspase-3.
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Academic Article
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Intramedullary spinal cord astrocytomas in children.
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Academic Article
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High-dose cyclophosphamide for poor-prognosis and recurrent pediatric brain tumors: a dose-escalation study.
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Academic Article
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Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas.
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Academic Article
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Gefitinib is effective against juvenile pilocytic astrocytoma in vitro.
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Academic Article
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Tamoxifen radiosensitization in human glioblastoma cell lines.
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Academic Article
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Chemotherapy for intracranial ependymomas.
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Academic Article
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Successful use of intracavitary bleomycin for low-grade astrocytoma tumor cyst.
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Academic Article
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Radiographic response at end of therapy with carboplatin and vincristine as a prognostic indicator in children with low-grade astrocytoma.
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Academic Article
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Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.
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Academic Article
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Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.
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Academic Article
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Vascular abnormalities in pediatric craniopharyngioma patients treated with radiation therapy.
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Academic Article
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Maximally safe resection followed by hypofractionated re-irradiation for locally recurrent ependymoma in children.
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Academic Article
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Experience with electrolyte levels after craniotomy for pediatric brain tumors.
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Academic Article
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Immune gene and cell enrichment is associated with a good prognosis in ependymoma.
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Academic Article
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Tumor vaccination for malignant brain tumors.
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Academic Article
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Radiation-induced glioblastoma multiforme in children treated for medulloblastoma with characteristics of both medulloblastoma and glioblastoma multiforme.
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Academic Article
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Germ cell tumors of the brainstem: report on two cases with pulmonary complications and a review of the literature.
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Academic Article
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PARP1 expression in pediatric central nervous system tumors.
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Academic Article
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Conventional MRI at presentation does not predict clinical response to radiation therapy in children with diffuse pontine glioma.
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Academic Article
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Rare nerve lesions of non-nerve sheath origin: a 17-year retrospective series.
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Academic Article
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Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines.
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Academic Article
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MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence.
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Academic Article
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Aurora kinase A as a rational target for therapy in glioblastoma.
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Academic Article
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Cytotoxicity of glioblastoma cells mediated ex vivo by varicella-zoster virus-specific T cells.
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Academic Article
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High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.
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Academic Article
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Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.
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Academic Article
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Targeting the enhancer of zeste homologue 2 in medulloblastoma.
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Academic Article
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Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas.
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Academic Article
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Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.
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Academic Article
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Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
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Academic Article
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MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.
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Academic Article
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Brainstem ganglioglioma successfully treated with vemurafenib.
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Academic Article
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Interpretation of magnetic resonance images in diffuse intrinsic pontine glioma: a survey of pediatric neurosurgeons.
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Academic Article
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Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.
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Academic Article
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Clinical and molecular characteristics of congenital glioblastoma.
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Academic Article
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Limited utility despite accuracy of the national SEER dataset for the study of craniopharyngioma.
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Academic Article
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Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.
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Academic Article
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Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.
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Concept
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Choroid Plexus Neoplasms
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Concept
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Nerve Sheath Neoplasms
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Concept
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Supratentorial Neoplasms
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Concept
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Central Nervous System Neoplasms
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Concept
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Brain Neoplasms
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Concept
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Neoplasms, Germ Cell and Embryonal
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Concept
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Tumor Suppressor Protein p53
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Concept
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Spinal Cord Neoplasms
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Concept
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Cerebral Ventricle Neoplasms
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Concept
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Neoplasms, Neuroepithelial
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Concept
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Skull Base Neoplasms
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Concept
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Peripheral Nervous System Neoplasms
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Concept
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Meningeal Neoplasms
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Concept
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DNA, Neoplasm
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Concept
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Biomarkers, Tumor
|
Concept
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Optic Nerve Neoplasms
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Concept
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Pituitary Neoplasms
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Concept
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Rhabdoid Tumor
|
Concept
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Neoplasms, Second Primary
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Concept
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Cancer Vaccines
|
Concept
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Pancreatic Neoplasms
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Concept
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Hypothalamic Neoplasms
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Concept
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Neoplasm Proteins
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Concept
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Neoplasm Staging
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Concept
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Neoplasms, Radiation-Induced
|
Concept
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Kidney Neoplasms
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Concept
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Drug Resistance, Neoplasm
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Concept
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Spinal Neoplasms
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Concept
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Infratentorial Neoplasms
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Concept
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Skull Neoplasms
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Concept
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Antibodies, Neoplasm
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Concept
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Tumor Cells, Cultured
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Concept
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Lymphocytes, Tumor-Infiltrating
|
Concept
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Abdominal Neoplasms
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Concept
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Gingival Neoplasms
|
Concept
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Neoplasms
|
Concept
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Neoplasm, Residual
|
Concept
|
Cell Line, Tumor
|
Concept
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Tumor Suppressor Proteins
|
Concept
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Neuroectodermal Tumors, Primitive
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Concept
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Neoplasm Recurrence, Local
|
Concept
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Brain Stem Neoplasms
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Concept
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Cerebellar Neoplasms
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Concept
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RNA, Neoplasm
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Concept
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Neoplasm Invasiveness
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Academic Article
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Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma.
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Academic Article
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Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma.
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Academic Article
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Preclinical high-dose acetaminophen with N-acetylcysteine rescue enhances the efficacy of cisplatin chemotherapy in atypical teratoid rhabdoid tumors.
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Academic Article
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Characterization of distinct immunophenotypes across pediatric brain tumor types.
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Academic Article
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The relationship between thyroid dose and diagnosis of primary hypothyroidism in pediatric brain tumor patients receiving craniospinal irradiation.
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Academic Article
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Fractionated stereotactic radiosurgery for recurrent ependymoma in children.
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Academic Article
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Radiation-induced gliomas in 2 pediatric patients with neurofibromatosis type 1: case study and summary of the literature.
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Academic Article
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Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.
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Academic Article
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Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
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Academic Article
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Patterns of care for craniopharyngioma: survey of members of the american association of neurological surgeons.
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Academic Article
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Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
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Academic Article
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Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.
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Academic Article
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Pediatric brainstem gangliogliomas show BRAF(V600E) mutation in a high percentage of cases.
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Academic Article
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Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors.
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Academic Article
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Massive dissemination from spinal cord gangliogliomas negative for BRAF V600E: report of two rare adult cases.
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Academic Article
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Pilomyxoid astrocytoma treated successfully with vemurafenib.
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Academic Article
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Using BRAF(V600E) as a marker of autophagy dependence in pediatric brain tumors.
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Academic Article
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CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy.
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Academic Article
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Cerebral radiation necrosis in pediatric patients.
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Academic Article
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BRAF VE1 immunoreactivity patterns in epithelioid glioblastomas positive for BRAF V600E mutation.
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Academic Article
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Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.
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Academic Article
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An open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).
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Academic Article
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Pilomyxoid Astrocytoma (PMA) Shows Significant Differences in Gene Expression vs. Pilocytic Astrocytoma (PA) and Variable Tendency Toward Maturation to PA.
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Academic Article
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Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma.
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Academic Article
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Hypofractionated Radiotherapy for Children With Diffuse Intrinsic Pontine Gliomas.
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Academic Article
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A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.
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Academic Article
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SOX10 Distinguishes Pilocytic and Pilomyxoid Astrocytomas From Ependymomas but Shows No Differences in Expression Level in Ependymomas From Infants Versus Older Children or Among Molecular Subgroups.
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Academic Article
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Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy.
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Academic Article
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Polo-like Kinase?1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.
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Academic Article
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Emerging evidence of anti-tumor immune control in the central nervous system.
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Academic Article
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Immunotherapeutic implications of the immunophenotype of pediatric brain tumors.
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Academic Article
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Vincristine and Vinblastine: Is checking bilirubin mandatory in children with Brain Tumors?
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Academic Article
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The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.
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Academic Article
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Desmoplastic infantile astrocytoma/ganglioglioma with rare BRAF V600D mutation.
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Academic Article
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Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.
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Academic Article
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Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
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Academic Article
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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
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Academic Article
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Retrovirus-mediated gene transfer as an approach to analyze neuroblastoma relapse after autologous bone marrow transplantation.
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Academic Article
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Mechanisms of selective killing of neuroblastoma cells by natural killer cells and lymphokine activated killer cells. Potential for residual disease eradication.
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Academic Article
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Pediatric low-grade gliomas: implications of the biologic era.
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Academic Article
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Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma.
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Academic Article
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Hypofractionated re-irradiation to the brainstem in children with recurrent brain tumors.
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Academic Article
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H3 K27M Mutation in Gangliogliomas can be Associated with Poor Prognosis.
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Academic Article
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Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach.
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Grant
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Molecular and Cellular Characterization of Prognostic Immune Response in Childhoo
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Academic Article
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NF-?B upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.
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Academic Article
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Tumor treating fields in pediatric high-grade glioma.
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Academic Article
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A pediatric trial of radiation/cetuximab followed by irinotecan/cetuximab in newly diagnosed diffuse pontine gliomas and high-grade astrocytomas: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study.
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Academic Article
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p16 Loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma.
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Academic Article
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Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study.
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Academic Article
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Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.
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Academic Article
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Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood.
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Academic Article
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Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.
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Academic Article
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Pediatric low-grade gliomas: next biologically driven steps.
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Academic Article
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Survival benefit of postoperative radiation in papillary meningioma: Analysis of the National Cancer Data Base.
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Academic Article
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Intracranial Ewing sarcoma: four pediatric examples.
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Academic Article
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Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
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Academic Article
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Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.
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Academic Article
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Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.
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Academic Article
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Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma.
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Academic Article
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Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells.
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Academic Article
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Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
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Academic Article
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Identification of FDA-Approved Oncology Drugs with Selective Potency in High-Risk Childhood Ependymoma.
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Academic Article
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Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.
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Academic Article
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Safety and feasibility of outpatient autologous stem cell transplantation in pediatric patients with primary central nervous system tumors.
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Academic Article
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Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma.
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Academic Article
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Diagnostic accuracy of neuroimaging in pediatric optic chiasm/sellar/suprasellar tumors.
|
Concept
|
Cancer Survivors
|
Concept
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Tumor Microenvironment
|
Concept
|
Neoplasm Grading
|
Grant
|
Investigation of a Novel Cancer Stem Cell Population in Ependymoma.
|
Academic Article
|
Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.
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Academic Article
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Bevacizumab in the treatment of radiation injury for children with central nervous system tumors.
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Academic Article
|
Effect of early-stage autophagy inhibition in BRAFV600E autophagy-dependent brain tumor cells.
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Academic Article
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Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
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Academic Article
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Targetable molecular alterations in congenital glioblastoma.
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Academic Article
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In vitro benchmarking of NF-?B inhibitors.
|
Academic Article
|
Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine.
|
Academic Article
|
Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.
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Academic Article
|
Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets.
|
Academic Article
|
Retrospective analysis of combination carboplatin and vinblastine for pediatric low-grade glioma.
|
Academic Article
|
A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups.
|
Grant
|
Epigenetic regulation of LDOC1 drives tumor biology in high risk ependymoma
|
Academic Article
|
Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images.
|
Academic Article
|
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
|
Academic Article
|
Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).
|
Academic Article
|
NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.
|
Academic Article
|
Targeting fibroblast growth factor receptors to combat aggressive ependymoma.
|
Academic Article
|
Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.
|
Academic Article
|
A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.
|
Academic Article
|
Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
|
Academic Article
|
Outcomes after first relapse of children with intracranial ependymoma treated on the second l'Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) protocol.
|
Academic Article
|
Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors.
|
Academic Article
|
Radiation Therapy for Young Children Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant for Primary Brain Tumors.
|
Academic Article
|
Pediatric pineal region masses: a single-center experience over 25?years.
|
Academic Article
|
Response assessment in paediatric intracranial ependymoma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
|
Academic Article
|
PDGFB:APOBEC3C fusion in congenital diffuse high-grade glioma of the brainstem.
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Academic Article
|
Thromboembolic toxicity observed with concurrent trametinib and lenalidomide therapy.
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Academic Article
|
Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma.
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Academic Article
|
Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: Safety, efficacy, biomarker, and pharmacokinetics-CheckMate 908.
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Academic Article
|
Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas.
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Academic Article
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Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study.
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Academic Article
|
Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial.
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Academic Article
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Mapping pediatric brain tumors to their origins in the developing cerebellum.
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Academic Article
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Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma.
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Academic Article
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Genetic Predictors of Neurocognitive Outcomes in Survivors of Pediatric Brain Tumors.
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Academic Article
|
Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
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Academic Article
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Genetic predictors of neurocognitive outcomes in survivors of pediatric brain tumors.
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Academic Article
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Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high grade glioma.
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