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Search Results to Nicholas K Foreman

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Foreman, Nicholas

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Item Type	Name
Academic Article	Decline in incidence of medulloblastoma in children.
Academic Article	Maternal diet and primitive neuroectodermal brain tumors in children.
Academic Article	Variation in survival of children with cancer within a region of the United Kingdom.
Academic Article	Magnetic resonance imaging and magnetic resonance angiography in long term survivors of acute lymphoblastic leukemia treated with cranial irradiation.
Academic Article	Radon in Devon and Cornwall and paediatric malignancies.
Academic Article	Intracranial ependymomas: analysis of prognostic factors in a population-based series.
Academic Article	Second-look surgery for incompletely resected fourth ventricle ependymomas: technical case report.
Academic Article	Chemotherapy for spinal cord astrocytoma.
Academic Article	Intracranial large vessel vasculopathy and anaplastic meningioma 19 years after cranial irradiation for acute lymphoblastic leukaemia.
Academic Article	Ki-67 immunolabelling index is a prognostic indicator in childhood posterior fossa ependymomas.
Academic Article	Adenovirus mediated gene therapy in a glioblastoma vaccine model; specific antitumor immunity and abrogation of immunosuppression.
Academic Article	Ependymomas in children.
Academic Article	Childhood malignancies in the south-west region of England, 1976-1985.
Academic Article	Pattern of recurrence in children with midline posterior fossa malignant neoplasms.
Academic Article	Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines.
Academic Article	Cystic metastatic cerebral neuroblastoma.
Academic Article	Experience with tamoxifen/etoposide in the treatment of a child with myxopapillary ependymoma.
Academic Article	Radon exposure and incidence of paediatric malignancies.
Academic Article	Rhabdoid glioblastoma.
Academic Article	Congenital malignant rhabdoid tumour of the gum margin.
Academic Article	Brain stem glioma in a child: false diagnosis of radiation necrosis with FDG PET.
Academic Article	Atypical teratoid/rhabdoid tumor of the central nervous system in children: an atypical series and review.
Academic Article	Intracranial germ cell tumors: a single institution experience and review of the literature.
Academic Article	Cord blood transplant in childhood ALL.
Academic Article	A study of sequential high dose cyclophosphamide and high dose carboplatin with peripheral stem-cell rescue in resistant or recurrent pediatric brain tumors.
Academic Article	Health status in 52 long-term survivors of pediatric brain tumors.
Academic Article	Midpoint CD34 measurement as a predictor of PBPC product yield in pediatric patients undergoing high-dose chemotherapy.
Academic Article	Predicting which children are at risk for ependymoma relapse.
Academic Article	MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
Academic Article	Molecular array analyses of 51 pediatric tumors shows overlap between malignant intracranial ectomesenchymoma and MPNST but not medulloblastoma or atypical teratoid rhabdoid tumor.
Academic Article	Unique molecular characteristics of radiation-induced glioblastoma.
Academic Article	Claudin 6 is a positive marker for atypical teratoid/rhabdoid tumors.
Academic Article	Unique molecular characteristics of pediatric myxopapillary ependymoma.
Academic Article	Bevacizumab as therapy for radiation necrosis in four children with pontine gliomas.
Academic Article	Pontine gliomas.
Academic Article	Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.
Academic Article	Creative arts therapy improves quality of life for pediatric brain tumor patients receiving outpatient chemotherapy.
Academic Article	Survey of MicroRNA expression in pediatric brain tumors.
Academic Article	Memory deficits in patients with pediatric CNS germ cell tumors.
Academic Article	Multinodular leptomeningeal metastases from ETANTR contain both small blue cell and maturing neuropil elements.
Academic Article	Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells.
Academic Article	Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma.
Academic Article	Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry.
Academic Article	Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.
Academic Article	Children's Oncology Group's 2013 blueprint for research: central nervous system tumors.
Academic Article	Development of an in-home standardized end-of-life treatment program for pediatric patients dying of brain tumors.
Academic Article	Epithelioid GBMs show a high percentage of BRAF V600E mutation.
Academic Article	Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma.
Academic Article	Immunomodulatory effects of human neuroblastoma cells transduced with a retroviral vector encoding interleukin-2.
Academic Article	Measurement of tamoxifen-induced apoptosis in glioblastoma by cytometric bead analysis of active caspase-3.
Academic Article	Intramedullary spinal cord astrocytomas in children.
Academic Article	High-dose cyclophosphamide for poor-prognosis and recurrent pediatric brain tumors: a dose-escalation study.
Academic Article	Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas.
Academic Article	Gefitinib is effective against juvenile pilocytic astrocytoma in vitro.
Academic Article	Tamoxifen radiosensitization in human glioblastoma cell lines.
Academic Article	Chemotherapy for intracranial ependymomas.
Academic Article	Successful use of intracavitary bleomycin for low-grade astrocytoma tumor cyst.
Academic Article	Radiographic response at end of therapy with carboplatin and vincristine as a prognostic indicator in children with low-grade astrocytoma.
Academic Article	Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.
Academic Article	Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.
Academic Article	Vascular abnormalities in pediatric craniopharyngioma patients treated with radiation therapy.
Academic Article	Maximally safe resection followed by hypofractionated re-irradiation for locally recurrent ependymoma in children.
Academic Article	Experience with electrolyte levels after craniotomy for pediatric brain tumors.
Academic Article	Immune gene and cell enrichment is associated with a good prognosis in ependymoma.
Academic Article	Tumor vaccination for malignant brain tumors.
Academic Article	Radiation-induced glioblastoma multiforme in children treated for medulloblastoma with characteristics of both medulloblastoma and glioblastoma multiforme.
Academic Article	Germ cell tumors of the brainstem: report on two cases with pulmonary complications and a review of the literature.
Academic Article	PARP1 expression in pediatric central nervous system tumors.
Academic Article	Conventional MRI at presentation does not predict clinical response to radiation therapy in children with diffuse pontine glioma.
Academic Article	Rare nerve lesions of non-nerve sheath origin: a 17-year retrospective series.
Academic Article	Inhibition of Aurora Kinase A enhances chemosensitivity of medulloblastoma cell lines.
Academic Article	MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence.
Academic Article	Aurora kinase A as a rational target for therapy in glioblastoma.
Academic Article	Cytotoxicity of glioblastoma cells mediated ex vivo by varicella-zoster virus-specific T cells.
Academic Article	High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.
Academic Article	Histone deacetylase inhibition decreases proliferation and potentiates the effect of ionizing radiation in atypical teratoid/rhabdoid tumor cells.
Academic Article	Targeting the enhancer of zeste homologue 2 in medulloblastoma.
Academic Article	Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas.
Academic Article	Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.
Academic Article	Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
Academic Article	MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.
Academic Article	Brainstem ganglioglioma successfully treated with vemurafenib.
Academic Article	Interpretation of magnetic resonance images in diffuse intrinsic pontine glioma: a survey of pediatric neurosurgeons.
Academic Article	Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.
Academic Article	Clinical and molecular characteristics of congenital glioblastoma.
Academic Article	Limited utility despite accuracy of the national SEER dataset for the study of craniopharyngioma.
Academic Article	Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells.
Academic Article	Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.
Concept	Choroid Plexus Neoplasms
Concept	Nerve Sheath Neoplasms
Concept	Supratentorial Neoplasms
Concept	Central Nervous System Neoplasms
Concept	Brain Neoplasms
Concept	Neoplasms, Germ Cell and Embryonal
Concept	Tumor Suppressor Protein p53
Concept	Spinal Cord Neoplasms
Concept	Cerebral Ventricle Neoplasms
Concept	Neoplasms, Neuroepithelial
Concept	Skull Base Neoplasms
Concept	Peripheral Nervous System Neoplasms
Concept	Meningeal Neoplasms
Concept	DNA, Neoplasm
Concept	Biomarkers, Tumor
Concept	Optic Nerve Neoplasms
Concept	Pituitary Neoplasms
Concept	Rhabdoid Tumor
Concept	Neoplasms, Second Primary
Concept	Cancer Vaccines
Concept	Pancreatic Neoplasms
Concept	Hypothalamic Neoplasms
Concept	Neoplasm Proteins
Concept	Neoplasm Staging
Concept	Neoplasms, Radiation-Induced
Concept	Kidney Neoplasms
Concept	Drug Resistance, Neoplasm
Concept	Spinal Neoplasms
Concept	Infratentorial Neoplasms
Concept	Skull Neoplasms
Concept	Antibodies, Neoplasm
Concept	Tumor Cells, Cultured
Concept	Lymphocytes, Tumor-Infiltrating
Concept	Abdominal Neoplasms
Concept	Gingival Neoplasms
Concept	Neoplasms
Concept	Neoplasm, Residual
Concept	Cell Line, Tumor
Concept	Tumor Suppressor Proteins
Concept	Neuroectodermal Tumors, Primitive
Concept	Neoplasm Recurrence, Local
Concept	Brain Stem Neoplasms
Concept	Cerebellar Neoplasms
Concept	RNA, Neoplasm
Concept	Neoplasm Invasiveness
Academic Article	Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma.
Academic Article	Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma.
Academic Article	Preclinical high-dose acetaminophen with N-acetylcysteine rescue enhances the efficacy of cisplatin chemotherapy in atypical teratoid rhabdoid tumors.
Academic Article	Characterization of distinct immunophenotypes across pediatric brain tumor types.
Academic Article	The relationship between thyroid dose and diagnosis of primary hypothyroidism in pediatric brain tumor patients receiving craniospinal irradiation.
Academic Article	Fractionated stereotactic radiosurgery for recurrent ependymoma in children.
Academic Article	Radiation-induced gliomas in 2 pediatric patients with neurofibromatosis type 1: case study and summary of the literature.
Academic Article	Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.
Academic Article	Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
Academic Article	Patterns of care for craniopharyngioma: survey of members of the american association of neurological surgeons.
Academic Article	Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
Academic Article	Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.
Academic Article	Pediatric brainstem gangliogliomas show BRAF(V600E) mutation in a high percentage of cases.
Academic Article	Autophagy inhibition improves chemosensitivity in BRAF(V600E) brain tumors.
Academic Article	Massive dissemination from spinal cord gangliogliomas negative for BRAF V600E: report of two rare adult cases.
Academic Article	Pilomyxoid astrocytoma treated successfully with vemurafenib.
Academic Article	Using BRAF(V600E) as a marker of autophagy dependence in pediatric brain tumors.
Academic Article	CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy.
Academic Article	Cerebral radiation necrosis in pediatric patients.
Academic Article	BRAF VE1 immunoreactivity patterns in epithelioid glioblastomas positive for BRAF V600E mutation.
Academic Article	Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.
Academic Article	An open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).
Academic Article	Pilomyxoid Astrocytoma (PMA) Shows Significant Differences in Gene Expression vs. Pilocytic Astrocytoma (PA) and Variable Tendency Toward Maturation to PA.
Academic Article	Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma.
Academic Article	Hypofractionated Radiotherapy for Children With Diffuse Intrinsic Pontine Gliomas.
Academic Article	A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma Cells.
Academic Article	SOX10 Distinguishes Pilocytic and Pilomyxoid Astrocytomas From Ependymomas but Shows No Differences in Expression Level in Ependymomas From Infants Versus Older Children or Among Molecular Subgroups.
Academic Article	Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy.
Academic Article	Polo-like Kinase?1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.
Academic Article	Emerging evidence of anti-tumor immune control in the central nervous system.
Academic Article	Immunotherapeutic implications of the immunophenotype of pediatric brain tumors.
Academic Article	Vincristine and Vinblastine: Is checking bilirubin mandatory in children with Brain Tumors?
Academic Article	The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.
Academic Article	Desmoplastic infantile astrocytoma/ganglioglioma with rare BRAF V600D mutation.
Academic Article	Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.
Academic Article	Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
Academic Article	Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Academic Article	Retrovirus-mediated gene transfer as an approach to analyze neuroblastoma relapse after autologous bone marrow transplantation.
Academic Article	Mechanisms of selective killing of neuroblastoma cells by natural killer cells and lymphokine activated killer cells. Potential for residual disease eradication.
Academic Article	Pediatric low-grade gliomas: implications of the biologic era.
Academic Article	Combined EphB2 receptor knockdown with radiation decreases cell viability and invasion in medulloblastoma.
Academic Article	Hypofractionated re-irradiation to the brainstem in children with recurrent brain tumors.
Academic Article	H3 K27M Mutation in Gangliogliomas can be Associated with Poor Prognosis.
Academic Article	Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach.
Grant	Molecular and Cellular Characterization of Prognostic Immune Response in Childhoo
Academic Article	NF-?B upregulation through epigenetic silencing of LDOC1 drives tumor biology and specific immunophenotype in Group A ependymoma.
Academic Article	Tumor treating fields in pediatric high-grade glioma.
Academic Article	A pediatric trial of radiation/cetuximab followed by irinotecan/cetuximab in newly diagnosed diffuse pontine gliomas and high-grade astrocytomas: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study.
Academic Article	p16 Loss and E2F/cell cycle deregulation in infant posterior fossa ependymoma.
Academic Article	Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study.
Academic Article	Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.
Academic Article	Characterization of 2 Novel Ependymoma Cell Lines With Chromosome 1q Gain Derived From Posterior Fossa Tumors of Childhood.
Academic Article	Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.
Academic Article	Pediatric low-grade gliomas: next biologically driven steps.
Academic Article	Survival benefit of postoperative radiation in papillary meningioma: Analysis of the National Cancer Data Base.
Academic Article	Intracranial Ewing sarcoma: four pediatric examples.
Academic Article	Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma.
Academic Article	Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.
Academic Article	Specific expression of PD-L1 in RELA-fusion supratentorial ependymoma: Implications for PD-1-targeted therapy.
Academic Article	Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma.
Academic Article	Durable regression of Medulloblastoma after regional and intravenous delivery of anti-HER2 chimeric antigen receptor T cells.
Academic Article	Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
Academic Article	Identification of FDA-Approved Oncology Drugs with Selective Potency in High-Risk Childhood Ependymoma.
Academic Article	Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.
Academic Article	Safety and feasibility of outpatient autologous stem cell transplantation in pediatric patients with primary central nervous system tumors.
Academic Article	Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma.
Academic Article	Diagnostic accuracy of neuroimaging in pediatric optic chiasm/sellar/suprasellar tumors.
Concept	Cancer Survivors
Concept	Tumor Microenvironment
Concept	Neoplasm Grading
Grant	Investigation of a Novel Cancer Stem Cell Population in Ependymoma.
Academic Article	Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.
Academic Article	Bevacizumab in the treatment of radiation injury for children with central nervous system tumors.
Academic Article	Effect of early-stage autophagy inhibition in BRAFV600E autophagy-dependent brain tumor cells.
Academic Article	Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors.
Academic Article	Targetable molecular alterations in congenital glioblastoma.
Academic Article	In vitro benchmarking of NF-?B inhibitors.
Academic Article	Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine.
Academic Article	Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.
Academic Article	Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets.
Academic Article	Retrospective analysis of combination carboplatin and vinblastine for pediatric low-grade glioma.
Academic Article	A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups.
Grant	Epigenetic regulation of LDOC1 drives tumor biology in high risk ependymoma
Academic Article	Robust deep learning classification of adamantinomatous craniopharyngioma from limited preoperative radiographic images.
Academic Article	Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Academic Article	Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1).
Academic Article	NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.
Academic Article	Targeting fibroblast growth factor receptors to combat aggressive ependymoma.
Academic Article	Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.
Academic Article	A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.
Academic Article	Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.
Academic Article	Outcomes after first relapse of children with intracranial ependymoma treated on the second l'Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) protocol.
Academic Article	Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors.
Academic Article	Radiation Therapy for Young Children Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant for Primary Brain Tumors.
Academic Article	Pediatric pineal region masses: a single-center experience over 25?years.
Academic Article	Response assessment in paediatric intracranial ependymoma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
Academic Article	PDGFB:APOBEC3C fusion in congenital diffuse high-grade glioma of the brainstem.
Academic Article	Thromboembolic toxicity observed with concurrent trametinib and lenalidomide therapy.
Academic Article	Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma.
Academic Article	Nivolumab with or without ipilimumab in pediatric patients with high-grade CNS malignancies: Safety, efficacy, biomarker, and pharmacokinetics-CheckMate 908.
Academic Article	Identification of HDAC4 as a potential therapeutic target and prognostic biomarker for ZFTA-fused ependymomas.
Academic Article	Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study.
Academic Article	Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial.
Academic Article	Mapping pediatric brain tumors to their origins in the developing cerebellum.
Academic Article	Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma.
Academic Article	Genetic Predictors of Neurocognitive Outcomes in Survivors of Pediatric Brain Tumors.
Academic Article	Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas.
Academic Article	Genetic predictors of neurocognitive outcomes in survivors of pediatric brain tumors.
Academic Article	Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high-grade glioma.

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Neoplasms