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Search Results to Steven H Abman

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Abman, Steven

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Item Type	Name
Academic Article	Experience with home oxygen in the management of infants with bronchopulmonary dysplasia.
Academic Article	Systemic hypertension in infants with bronchopulmonary dysplasia.
Academic Article	Inhaled nitric oxide for persistent pulmonary hypertension of the newborn: the physiology matters!
Academic Article	Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn.
Academic Article	Pathophysiology and treatment of bronchopulmonary dysplasia. Current issues.
Academic Article	Elevated immunoreactive endothelin-1 levels in newborn infants with persistent pulmonary hypertension.
Academic Article	Low-dose inhalation nitric oxide in persistent pulmonary hypertension of the newborn.
Academic Article	Atrial natriuretic peptide and nitric oxide in children with pulmonary hypertension after surgical repair of congenital heart disease.
Academic Article	Inhalational nitric oxide in pulmonary parenchymal and vascular disease.
Academic Article	Mechanisms of abnormal vasoreactivity in persistent pulmonary hypertension of the newborn infant.
Academic Article	Combined therapy with inhaled nitric oxide and intravenous prostacyclin in an infant with alveolar-capillary dysplasia.
Academic Article	Intravascular ultrasonic characteristics and vasoreactivity of the pulmonary vasculature in children with pulmonary hypertension.
Academic Article	Hemodynamic effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension.
Academic Article	Effects of chronic hypoxia and altered hemodynamics on endothelial nitric oxide synthase and preproendothelin-1 expression in the adult rat lung.
Academic Article	Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity.
Academic Article	Increased lung preproET-1 and decreased ETB-receptor gene expression in fetal pulmonary hypertension.
Academic Article	Dipyridamole attenuates rebound pulmonary hypertension after inhaled nitric oxide withdrawal in postoperative congenital heart disease.
Academic Article	Chronic pulmonary hypertension in utero impairs endothelium-dependent vasodilation.
Academic Article	Response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn: relationship to baseline oxygenation.
Academic Article	Chronic intrauterine pulmonary hypertension increases preproendothelin-1 and decreases endothelin B receptor mRNA expression in the ovine fetal lung.
Academic Article	Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension.
Academic Article	Infant lung function after inhaled nitric oxide therapy for persistent pulmonary hypertension of the newborn.
Academic Article	Efficacy of inhalational nitric oxide therapy in the clinical management of persistent pulmonary hypertension of the newborn.
Academic Article	Variable expression of endothelial NO synthase in three forms of rat pulmonary hypertension.
Academic Article	Abnormal vasoreactivity in the pathophysiology of persistent pulmonary hypertension of the newborn.
Academic Article	Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation.
Academic Article	Role of inhaled nitric oxide in treatment of neonatal pulmonary hypertension.
Academic Article	Circulating immunoreactive endothelin-1 in children with pulmonary hypertension. Association with acute hypoxic pulmonary vasoreactivity.
Academic Article	Neonatal dexamethasone treatment increases the risk for pulmonary hypertension in adult rats.
Academic Article	Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension.
Academic Article	Abnormal lung growth and the development of pulmonary hypertension in the Fawn-Hooded rat.
Academic Article	Selective and sustained pulmonary vasodilation with inhalational nitric oxide therapy in a child with idiopathic pulmonary hypertension.
Academic Article	Brief perinatal hypoxia increases severity of pulmonary hypertension after reexposure to hypoxia in infant rats.
Academic Article	Inhaled nitric oxide therapy of pulmonary hypertension and respiratory failure in premature and term neonates.
Academic Article	Prolonged endothelin B receptor blockade causes pulmonary hypertension in the ovine fetus.
Academic Article	Clinical pathophysiology of persistent pulmonary hypertension of the newborn and the role of inhaled nitric oxide therapy.
Academic Article	Endothelin B receptor deficiency potentiates ET-1 and hypoxic pulmonary vasoconstriction.
Academic Article	Inhaled nitric oxide: current and future uses in neonates.
Academic Article	Chronic intrauterine pulmonary hypertension alters endothelin receptor activity in the ovine fetal lung.
Academic Article	Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: a case report.
Academic Article	Longitudinal follow-up of a cohort of newborn infants treated with inhaled nitric oxide for persistent pulmonary hypertension.
Academic Article	Monitoring cardiovascular function in infants with chronic lung disease of prematurity.
Academic Article	Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure.
Academic Article	Impact of new treatments for neonatal pulmonary hypertension on extracorporeal membrane oxygenation use and outcome.
Academic Article	Role of platelet-derived growth factor in vascular remodeling during pulmonary hypertension in the ovine fetus.
Academic Article	Intrauterine hypertension decreases lung VEGF expression and VEGF inhibition causes pulmonary hypertension in the ovine fetus.
Academic Article	Acute hemodynamic effects of pulsed delivery of low flow nasal nitric oxide in children with pulmonary hypertension.
Academic Article	Mild hypoxia impairs alveolarization in the endothelial nitric oxide synthase-deficient mouse.
Academic Article	The pulmonary circulation in bronchopulmonary dysplasia.
Academic Article	New developments in the pathogenesis and treatment of neonatal pulmonary hypertension.
Academic Article	Acute hemodynamic effects and home therapy using a novel pulsed nasal nitric oxide delivery system in children and young adults with pulmonary hypertension.
Academic Article	Neonatal pulmonary hypertension: a physiologic approach to treatment.
Academic Article	Superoxide dismutase improves gas exchange and pulmonary hemodynamics in premature lambs.
Academic Article	Pulmonary hypertension impairs alveolarization and reduces lung growth in the ovine fetus.
Academic Article	Pulmonary vasodilator therapy in congenital diaphragmatic hernia: acute, late, and chronic pulmonary hypertension.
Academic Article	Acute intrauterine pulmonary hypertension impairs endothelium-dependent vasodilation in the ovine fetus.
Academic Article	Changes in lung eicosanoid content during normal and abnormal transition in perinatal lambs.
Academic Article	rhVEGF treatment preserves pulmonary vascular reactivity and structure in an experimental model of pulmonary hypertension in fetal sheep.
Academic Article	Effects of long-term bosentan in children with pulmonary arterial hypertension.
Academic Article	Effects of sildenafil on pulmonary hypertension and exercise tolerance in severe cystic fibrosis-related lung disease.
Academic Article	Pulmonary hypertension in older children: new approaches and therapies.
Academic Article	BAY 41-2272, a direct activator of soluble guanylate cyclase, reduces right ventricular hypertrophy and prevents pulmonary vascular remodeling during chronic hypoxia in neonatal rats.
Academic Article	Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines.
Academic Article	ABCA3 deficiency presenting as persistent pulmonary hypertension of the newborn.
Academic Article	Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease.
Academic Article	Chronic intrauterine pulmonary hypertension increases endothelial cell Rho kinase activity and impairs angiogenesis in vitro.
Academic Article	Role of endothelin receptor antagonists in the treatment of pulmonary arterial hypertension.
Academic Article	Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension.
Academic Article	Development and pathology of pulmonary hypertension.
Academic Article	Inhaled nitric oxide improves lung structure and pulmonary hypertension in a model of bleomycin-induced bronchopulmonary dysplasia in neonatal rats.
Academic Article	Pulmonary hypertension in children: a historical overview.
Academic Article	Moderate postnatal hyperoxia accelerates lung growth and attenuates pulmonary hypertension in infant rats after exposure to intra-amniotic endotoxin.
Academic Article	Estradiol improves pulmonary hemodynamics and vascular remodeling in perinatal pulmonary hypertension.
Academic Article	Recent progress in understanding pediatric pulmonary hypertension.
Academic Article	Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension.
Academic Article	Pulmonary vascular effects of serotonin and selective serotonin reuptake inhibitors in the late-gestation ovine fetus.
Academic Article	Excess soluble vascular endothelial growth factor receptor-1 in amniotic fluid impairs lung growth in rats: linking preeclampsia with bronchopulmonary dysplasia.
Academic Article	Chronic hypertension impairs flow-induced vasodilation and augments the myogenic response in fetal lung.
Academic Article	Failure of postnatal adaptation of the pulmonary circulation after chronic intrauterine pulmonary hypertension in fetal lambs.
Academic Article	Endothelin-1 impairs angiogenesis in vitro through Rho-kinase activation after chronic intrauterine pulmonary hypertension in fetal sheep.
Academic Article	Pulmonary vascular disease in bronchopulmonary dysplasia: pulmonary hypertension and beyond.
Academic Article	Serotonin contributes to high pulmonary vascular tone in a sheep model of persistent pulmonary hypertension of the newborn.
Academic Article	Acute and chronic fetal pulmonary hypertension alter pulmonary vasoreactivity.
Academic Article	Pulmonary vascular response to oxygen in infants with severe bronchopulmonary dysplasia.
Academic Article	Noninvasive delivery of inhaled nitric oxide therapy for late pulmonary hypertension in newborn infants with congenital diaphragmatic hernia.
Academic Article	Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.
Academic Article	Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.
Academic Article	Nitric oxide and prostacyclin treatment of an infant with primary pulmonary hypertension.
Academic Article	Pathogenesis and treatment of neonatal and postnatal pulmonary hypertension.
Academic Article	Clinical responses to prolonged treatment of persistent pulmonary hypertension of the newborn with low doses of inhaled nitric oxide.
Academic Article	Inhalational nitric oxide therapy for persistent pulmonary hypertension of the newborn.
Academic Article	Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus.
Academic Article	Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus.
Academic Article	Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn.
Academic Article	Pulmonary vascular effects of nitric oxide-cGMP augmentation in a model of chronic pulmonary hypertension in fetal and neonatal sheep.
Academic Article	Inhaled nitric oxide and high frequency oscillatory ventilation in persistent pulmonary hypertension of the newborn.
Academic Article	High-frequency oscillatory ventilation augments the response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn: Nitric Oxide Study Group.
Academic Article	The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia.
Academic Article	Vascular endothelial growth factor improves pulmonary vascular reactivity and structure in an experimental model of chronic pulmonary hypertension in fetal sheep.
Academic Article	Congenital pulmonary venous stenosis presenting as persistent pulmonary hypertension of the newborn.
Academic Article	Chronic intrauterine pulmonary hypertension decreases calcium-sensitive potassium channel mRNA expression.
Academic Article	Inhaled ethyl nitrite gas for persistent pulmonary hypertension in infants.
Academic Article	Inhaled nitric oxide attenuates pulmonary hypertension and improves lung growth in infant rats after neonatal treatment with a VEGF receptor inhibitor.
Academic Article	Pulmonary vascular effects of inhaled nitric oxide and oxygen tension in bronchopulmonary dysplasia.
Academic Article	Pulmonary artery hypertension and sleep-disordered breathing: ACCP evidence-based clinical practice guidelines.
Academic Article	Recent advances in the pathogenesis and treatment of persistent pulmonary hypertension of the newborn.
Academic Article	Intrauterine pulmonary hypertension impairs angiogenesis in vitro: role of vascular endothelial growth factor nitric oxide signaling.
Academic Article	Short- and long-term effects of inhaled iloprost therapy in children with pulmonary arterial hypertension.
Academic Article	Effects of long-term sildenafil treatment for pulmonary hypertension in infants with chronic lung disease.
Academic Article	Cinaciguat, a soluble guanylate cyclase activator, causes potent and sustained pulmonary vasodilation in the ovine fetus.
Academic Article	Improving outcomes for pulmonary vascular disease.
Academic Article	Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension.
Academic Article	Management of hyponatremia in infants with bronchopulmonary dysplasia.
Academic Article	A 7-year-old with pulmonary hypertension.
Academic Article	National Heart, Lung, and Blood Institute Workshop: improving outcomes for pulmonary vascular disease.
Academic Article	Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity.
Concept	Hypertension
Concept	Hypertension, Pulmonary
Academic Article	Endothelial colony-forming cell conditioned media promote angiogenesis in vitro and prevent pulmonary hypertension in experimental bronchopulmonary dysplasia.
Academic Article	Nitric oxide deficiency and endothelial dysfunction in pulmonary arterial hypertension.
Academic Article	Pediatric pulmonary hypertension.
Academic Article	Inhaled nitric oxide for the treatment of pulmonary arterial hypertension.
Academic Article	Pulmonary artery endothelial cell dysfunction and decreased populations of highly proliferative endothelial cells in experimental congenital diaphragmatic hernia.
Academic Article	Endothelin-1 decreases endothelial PPAR? signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension.
Academic Article	Peroxisome proliferator activated receptor-?-Rho-kinase interactions contribute to vascular remodeling after chronic intrauterine pulmonary hypertension.
Academic Article	Pulmonary hypertension: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.
Academic Article	Chronic intrauterine pulmonary hypertension increases main pulmonary artery stiffness and adventitial remodeling in fetal sheep.
Academic Article	Histologic identification of prominent intrapulmonary anastomotic vessels in severe congenital diaphragmatic hernia.
Academic Article	Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia.
Academic Article	[Pediatric pulmonary hypertension].
Academic Article	Hospitalizations of Children With Pulmonary Hypertension: Implications for Improving Care.
Academic Article	Beyond the 6-Minute Walk Test for Assessing Pediatric Pulmonary Hypertension: Making Strides Through Combination End Points.
Academic Article	Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society.
Academic Article	Pulmonary Hypertension and Vascular Abnormalities in Bronchopulmonary Dysplasia.
Academic Article	Intrauterine endotoxin-induced impairs pulmonary vascular function and right ventricular performance in infant rats and improvement with early vitamin D therapy.
Academic Article	Lack of EC-SOD worsens alveolar and vascular development in a neonatal mouse model of bleomycin-induced bronchopulmonary dysplasia and pulmonary hypertension.
Academic Article	Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension.
Academic Article	Intrapulmonary Bronchopulmonary Anastomoses and Plexiform Lesions in Idiopathic Pulmonary Arterial Hypertension.
Academic Article	An Unusual Etiology of Infantile Hemoptysis.
Academic Article	Pediatric Pulmonary Hypertension.
Academic Article	Persistent Challenges in Pediatric Pulmonary Hypertension.
Academic Article	Increased Lung Expression of Anti-Angiogenic Factors in Down Syndrome: Potential Role in Abnormal Lung Vascular Growth and the Risk for Pulmonary Hypertension.
Academic Article	New guidelines for managing pulmonary hypertension: what the pediatrician needs to know.
Academic Article	Towards improving the care of children with pulmonary hypertension: The rationale for developing a Pediatric Pulmonary Hypertension Network.
Academic Article	Endothelin-1-Rho kinase interactions impair lung structure and cause pulmonary hypertension after bleomycin exposure in neonatal rat pups.
Academic Article	Pulmonary Hypertension in Preterm Infants with Bronchopulmonary Dysplasia.
Academic Article	Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.
Academic Article	Translational Advances in the Field of Pulmonary Hypertension. Focusing on Developmental Origins and Disease Inception for the Prevention of Pulmonary Hypertension.
Academic Article	Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension.
Academic Article	Antenatal Determinants of Bronchopulmonary Dysplasia and Late Respiratory Disease in Preterm Infants.
Academic Article	Apparent Aortic Stiffness in Children With Pulmonary Arterial Hypertension: Existence of Vascular Interdependency?
Academic Article	Fetal Vascular Origins of Bronchopulmonary Dysplasia.
Grant	Role of VEGF in Perinatal Hypertension
Grant	MECHANISMS OF ABNORMAL PERINATAL VASOREACTIVITY
Grant	Phase II Trial of Sildenafil in Newborns with Persistent Pulmonary Hyptertension
Grant	Genetic Basis for Impaired Angiogenic Signaling in BPD
Grant	Data Fusion: A Sustainable, Scalable, Open Source Registry Advancing PVD Research
Grant	MECHANISMS OF ABNORMAL PERINATAL VASOREACTIVITY
Academic Article	Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report.
Academic Article	Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia.
Academic Article	Proteomic Profiles Associated with Early Echocardiogram Evidence of Pulmonary Vascular Disease in Preterm Infants.
Academic Article	Measuring Flow Hemodynamic Indices and Oxygen Consumption in Children with Pulmonary Hypertension: A Comparison of Catheterization and Phase-Contrast MRI.
Academic Article	An Approach to Children with Pulmonary Edema at High Altitude.
Academic Article	Effect of electrical dyssynchrony on left and right ventricular mechanics in children with pulmonary arterial hypertension.
Academic Article	The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension.
Academic Article	Proximal pulmonary vascular stiffness as a prognostic factor in children with pulmonary arterial hypertension.
Academic Article	Noninvasive wave intensity analysis predicts functional worsening in children with pulmonary arterial hypertension.
Academic Article	Clinical Characteristics and Risk Factors for Developing Pulmonary Hypertension in Children with Down Syndrome.
Academic Article	Recent advances in antenatal factors predisposing to bronchopulmonary dysplasia.
Academic Article	Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management.
Grant	Role of VEGF in Perinatal Hypertension
Academic Article	Pulmonary Hypertension Secondary to Scurvy in a Developmentally Typical Child.
Academic Article	Acute Vasoreactivity Testing during Cardiac Catheterization of Neonates with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension.
Academic Article	Differences in pulmonary arterial flow hemodynamics between children and adults with pulmonary arterial hypertension as assessed by 4D-flow CMR studies.
Academic Article	Response: Still puzzling about a clear definition of pulmonary arterial hypertension in newborns.
Concept	Familial Primary Pulmonary Hypertension
Academic Article	EXPRESS: Acute Vasoreactivity Testing in Pediatric Idiopathic Pulmonary Arterial Hypertension: an international Survey on Current Practice.
Academic Article	Phenotype characterisation of TBX4 mutation and deletion carriers with neonatal and paediatric pulmonary hypertension.
Academic Article	Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry.
Academic Article	EXPRESS: Angiogenic Profile Identifies Pulmonary Hypertension in Children with Down Syndrome.
Academic Article	Oxygen Therapy and Pulmonary Hypertension in Preterm Infants.
Academic Article	Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants.
Academic Article	Early Disruption of VEGF Receptor Signaling and the Risk for Adult Emphysema.
Academic Article	Adverse drug event rates in pediatric pulmonary hypertension: a comparison of real-world data sources.
Academic Article	Novel measures of left ventricular electromechanical discoordination predict clinical outcomes in children with pulmonary arterial hypertension.
Academic Article	Early angiogenic proteins associated with high risk for bronchopulmonary dysplasia and pulmonary hypertension in preterm infants.
Academic Article	rhIGF-1/BP3 Preserves Lung Growth and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia.
Academic Article	Persistent pulmonary hypertension of the newborn.
Academic Article	The many challenges to the field of pediatric pulmonology posed by pediatric pulmonary hypertension and the path forward.
Academic Article	Practice patterns of pulmonary hypertension secondary to left heart disease among pediatric pulmonary hypertension providers.
Academic Article	Short-Term Effects of Inhaled Nitric Oxide on Right Ventricular Flow Hemodynamics by 4-Dimensional-Flow Magnetic Resonance Imaging in Children With Pulmonary Arterial Hypertension.
Academic Article	Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances.
Academic Article	Pulmonary Hypertension: The Hidden Danger for Newborns.
Academic Article	Characterisation of paediatric pulmonary hypertensive vascular disease from the PPHNet Registry.
Grant	1/2 Kids MoD PAH Trial: Mono- vs. Duo-Therapy In Pediatric Pulmonary Arterial Hypertension
Academic Article	Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension.
Academic Article	Vascular Disorders of Pregnancy Increase Susceptibility to Neonatal Pulmonary Hypertension in High-Altitude Populations.
Academic Article	Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network.
Academic Article	Pulmonary vasodilator strategies in neonates with acute hypoxemic respiratory failure and pulmonary hypertension.
Academic Article	Of Registries and Disease Classification: Unmasking the Challenges of Pediatric Pulmonary Hypertension.
Academic Article	Clinical significance of pulmonary hypertension in interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute's innovative drug development initiative-Group 3 pulmonary hypertension.
Academic Article	Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry.
Academic Article	Characterization of Early Pulmonary Hypertension in Infants Born Preterm: A Key Step Toward Improving Outcomes.
Academic Article	Novel use of riociguat in infants with severe pulmonary arterial hypertension unable to wean from inhaled nitric oxide.
Academic Article	Hemodynamic Characterization of Neonates With Congenital Diaphragmatic Hernia-Associated Pulmonary Hypertension by Cardiac Catheterization.
Academic Article	Discharge Practices for Infants with Bronchopulmonary Dysplasia: A Survey of National Experts.
Academic Article	Safety and Feasibility of Riociguat Therapy for the Treatment of Chronic Pulmonary Arterial Hypertension in Infancy.
Academic Article	Practices and Outcomes from a Prospective, Multicenter Registry for Preterm Newborns with Pulmonary Hypertension.
Academic Article	Long-Term Effect of TBX4 Germline Mutation on Pulmonary Clinico-Histopathologic Phenotype.
Academic Article	Kids Mod PAH trial: A multicenter trial comparing mono- versus duo-therapy for initial treatment of pediatric pulmonary hypertension.
Academic Article	Patent Ductus Arteriosus and Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Bayesian Meta-Analysis.

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Hypertension