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Search Results to Craig T. Jordan

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Jordan, Craig

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Item Type	Name
Academic Article	The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells.
Academic Article	Considerations for targeting malignant stem cells in leukemia.
Academic Article	A new approach to treatment of acute myelogenous leukemia using targeted therapy in combination with standard chemotherapy.
Academic Article	Feverfew: weeding out the root of leukaemia.
Academic Article	Searching for leukemia stem cells--not yet the end of the road?
Academic Article	Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8).
Academic Article	Preferential loss of mismatch repair function in refractory and relapsed acute myeloid leukemia: potential contribution to AML progression.
Academic Article	Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.
Academic Article	Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1).
Academic Article	Regulation of myeloid leukaemia by the cell-fate determinant Musashi.
Academic Article	Leukemia stem cells and microenvironment: biology and therapeutic targeting.
Academic Article	Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells.
Academic Article	Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines.
Academic Article	Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia.
Academic Article	Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.
Academic Article	Targeting the most critical cells: approaching leukemia therapy as a problem in stem cell biology.
Academic Article	Genetic manipulation of primitive leukemic and normal hematopoietic cells using a novel method of adenovirus-mediated gene transfer.
Academic Article	Mechanisms controlling pathogenesis and survival of leukemic stem cells.
Academic Article	The molecular basis of leukemia.
Academic Article	The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells.
Academic Article	An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.
Academic Article	Monoclonal antibodies against IREM-1: potential for targeted therapy of AML.
Academic Article	Targeting myeloid leukemia stem cells.
Academic Article	High-risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells.
Academic Article	The NF (Nuclear factor)-?B inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.
Academic Article	Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Academic Article	Leukemia stem cells in 2010: current understanding and future directions.
Academic Article	Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture.
Academic Article	Leukemia stemness signatures step toward the clinic.
Academic Article	BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.
Concept	Leukemia, Myeloid
Concept	Leukemia, Myeloid, Acute
Concept	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Academic Article	In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling.
Academic Article	Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
Academic Article	A phase I study using bortezomib with weekly idarubicin for treatment of elderly patients with acute myeloid leukemia.
Academic Article	Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells.
Academic Article	A phase I study of decitabine and rapamycin in relapsed/refractory AML.
Academic Article	Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity.
Academic Article	Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization.
Academic Article	Aldehyde dehydrogenases in acute myeloid leukemia.
Academic Article	The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.
Academic Article	Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia.
Academic Article	Targeting acute myeloid leukemia stem cells: a review and principles for the development of clinical trials.
Academic Article	The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis.
Academic Article	Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.
Academic Article	Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia.
Academic Article	Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor Cells.
Academic Article	MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
Academic Article	Acute myeloid leukaemia.
Academic Article	Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.
Academic Article	The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia.
Academic Article	Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.
Academic Article	Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.
Academic Article	ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
Academic Article	Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.
Academic Article	Identification of a melampomagnolide B analog as a potential lead molecule for treatment of acute myelogenous leukemia.
Academic Article	Therapeutic targeting of acute myeloid leukemia stem cells.
Academic Article	Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.
Grant	Cellular and Molecular Studies of Leukemic Stem Cellss
Grant	Oncogene Cooperativity in Leukemia Stem Cells
Grant	Characterization and targeting of leukemia stem cell metabolism
Academic Article	A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.
Academic Article	Micelle Delivery of Parthenolide to Acute Myeloid Leukemia Cells.
Academic Article	AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.
Academic Article	Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes.
Academic Article	Functional genomic landscape of acute myeloid leukaemia.
Academic Article	Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.
Academic Article	Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.
Academic Article	Why are hypomethylating agents or low-dose cytarabine and venetoclax so effective?
Academic Article	Sequential azacitidine and lenalidomide for patients with relapsed and refractory acute myeloid leukemia: Clinical results and predictive modeling using computational analysis.
Academic Article	Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.
Academic Article	Real-world experience of venetoclax with azacitidine for untreated patients with acute myeloid leukemia.
Academic Article	Can we selectively target AML stem cells?
Grant	Metabolic mechanisms of venetoclax resistance in acute myeloid leukemia stem cells
Academic Article	Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.
Academic Article	Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.
Grant	Therapeutic Targeting of Human AML Stem Cells
Academic Article	The propriety of upgrading responses to venetoclax?+?azacitidine in newly diagnosed patients with acute myeloid leukemia.
Academic Article	Enriching for human acute myeloid leukemia stem cells using reactive oxygen species-based cell sorting.
Academic Article	Targeting Energy Metabolism in Cancer Stem Cells: Progress and Challenges in Leukemia and Solid Tumors.
Academic Article	Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells.
Academic Article	Venetoclax and azacitidine compared with induction chemotherapy for newly diagnosed patients with acute myeloid leukemia.
Academic Article	Venetoclax and azacitidine followed by allogeneic transplant results in excellent outcomes and may improve outcomes versus maintenance therapy among newly diagnosed AML patients older than 60.
Academic Article	The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.
Academic Article	Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Academic Article	Outcomes Are Similar After Allogeneic Hematopoietic Stem Cell Transplant for Newly Diagnosed Acute Myeloid Leukemia Patients who Received Venetoclax?+?Azacitidine Versus Intensive Chemotherapy.
Academic Article	Machine Learning-Based Exploratory Clinical Decision Support for Newly Diagnosed Patients With Acute Myeloid Leukemia Treated With 7 + 3 Type Chemotherapy or Venetoclax/Azacitidine.
Academic Article	Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation.
Academic Article	HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia.
Academic Article	Therapy-Resistant Acute Myeloid Leukemia Stem Cells Are Resensitized to Venetoclax + Azacitidine by Targeting Fatty Acid Desaturases 1 and 2.
Academic Article	Higher-dose venetoclax with measurable residual disease-guided azacitidine discontinuation in newly diagnosed acute myeloid leukemia.
Academic Article	Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.
Academic Article	Multi-gene measurable residual disease assessed by digital polymerase chain reaction has clinical and biological utility in acute myeloid leukemia patients receiving venetoclax/azacitidine.

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Leukemia Myeloid