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Search Results to Roberta Pelanda

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Pelanda, Roberta

One or more keywords matched the following items that are connected to Pelanda, Roberta

Item Type	Name
Academic Article	Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification.
Academic Article	Ku80 is required for immunoglobulin isotype switching.
Academic Article	From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins.
Academic Article	A prematurely expressed Ig(kappa) transgene, but not V(kappa)J(kappa) gene segment targeted into the Ig(kappa) locus, can rescue B cell development in lambda5-deficient mice.
Academic Article	Cre recombinase-controlled expression of the mb-1 allele.
Academic Article	V(D)J recombination in mature B cells: a mechanism for altering antibody responses.
Academic Article	Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice.
Academic Article	Receptor editing is the main mechanism of B cell tolerance toward membrane antigens.
Academic Article	Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo.
Academic Article	Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens.
Academic Article	Receptor editing for better or for worse.
Academic Article	Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation.
Academic Article	Arhgef1 is required by T cells for the development of airway hyperreactivity and inflammation.
Academic Article	Ig allotypic inclusion does not prevent B cell development or response.
Academic Article	TLR agonists promote marginal zone B cell activation and facilitate T-dependent IgM responses.
Academic Article	Lsc activity is controlled by oligomerization and regulates integrin adhesion.
Academic Article	Tolerance, immune regulation, and autoimmunity: cells and cytokines that make a difference.
Academic Article	Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity.
Academic Article	BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling.
Academic Article	Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2r?null mouse model: a multivariable optimization approach.
Academic Article	Central B-cell tolerance: where selection begins.
Academic Article	Antigen and cytokine receptor signals guide the development of the na?ve mature B cell repertoire.
Academic Article	Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation.
Academic Article	Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes.
Academic Article	B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.
Academic Article	Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components.
Academic Article	Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response.
Academic Article	Testing gene function early in the B cell lineage in mb1-cre mice.
Academic Article	Yin Yang 1 is a critical regulator of B-cell development.
Academic Article	Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation.
Academic Article	S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development.
Academic Article	Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
Academic Article	Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.
Academic Article	Efficient generation of B lymphocytes by recognition of self-antigens.
Academic Article	Mouse marginal zone B cells harbor specificities similar to human broadly neutralizing HIV antibodies.
Academic Article	Murine B cell development and antibody responses to model antigens are not impaired in the absence of the TNF receptor GITR.
Academic Article	Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity.
Academic Article	Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice.
Concept	Cell Movement
Concept	Hematopoietic Stem Cells
Concept	Precursor Cells, B-Lymphoid
Concept	Active Transport, Cell Nucleus
Concept	Lymphoma, Large B-Cell, Diffuse
Concept	Cell Lineage
Concept	Receptors, Antigen, T-Cell
Concept	Hematopoietic Stem Cell Transplantation
Concept	Cell Nucleus
Concept	Cell Division
Concept	COS Cells
Concept	Cell Communication
Concept	Cell Survival
Concept	Receptors, Cell Surface
Concept	Cell Adhesion
Concept	Cell Membrane
Concept	Cell Membrane Structures
Concept	Cell Culture Techniques
Concept	B-Cell Activating Factor
Concept	B-Cell Activation Factor Receptor
Concept	Lymphoma, B-Cell
Concept	Dendritic Cells
Concept	Antigen-Presenting Cells
Concept	Th2 Cells
Concept	Cell Line
Concept	Tumor Cells, Cultured
Concept	Cell Differentiation
Concept	Bone Marrow Cells
Concept	Receptors, Antigen, B-Cell
Concept	Cell Line, Tumor
Concept	Plasma Cells
Concept	Cell Polarity
Concept	Cells, Cultured
Concept	Stem Cells
Concept	Cell Separation
Concept	Cell Proliferation
Academic Article	B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia.
Academic Article	Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression.
Academic Article	Dual immunoglobulin light chain B cells: Trojan horses of autoimmunity?
Academic Article	Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response.
Academic Article	Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodies.
Academic Article	CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
Academic Article	Receptor editing and genetic variability in human autoreactive B cells.
Grant	Analysis of Human B Cell Tolerance in Humanized Mice
Grant	Human B Cell Development and Function in Humanized Mice Expressing Human BAFF
Grant	Tolerance in polyclonal and oligoclonal immune systems
Grant	Tolerance in Polyclonal and Oligoclonal Immune Systems
Grant	Modulatory signaling motifs in B cell antigen receptor function
Grant	Studies of human B cell tolerance, from a humanized mouse model to human beings
Grant	Developing a new model for EBV-mediated T cell diseases
Grant	Testing an alternative model of central B cell tolerance
Academic Article	Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice.
Academic Article	Cytokine-Producing B Cells Promote Immune-Mediated Bile Duct Injury in Murine Biliary Atresia.
Academic Article	Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance.
Academic Article	Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice.
Academic Article	Silencing of TLM B cells by chronic HIV infection.
Academic Article	Conditional Selection of B Cells in Mice With an Inducible B Cell Development.
Academic Article	Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus.
Academic Article	Corrigendum: Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance.
Academic Article	Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.
Concept	Programmed Cell Death 1 Receptor
Academic Article	Active PI3K abrogates central tolerance in high-avidity autoreactive B cells.
Academic Article	LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling.
Grant	Role and mechanisms of the PI3K pathway in B cell tolerance
Academic Article	Histone H2A-Reactive B Cells Are Functionally Anergic in Healthy Mice With Potential to Provide Humoral Protection Against HIV-1.
Academic Article	RX-5902, a novel ?-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.
Grant	Contribution of c-Maf to regulatory B cells and antibody-secreting cells
Academic Article	Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.
Academic Article	Graft-derived extracellular vesicles transported across subcapsular sinus macrophages elicit B cell alloimmunity after transplantation.
Academic Article	Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.
Academic Article	B-cell intrinsic and extrinsic signals that regulate central tolerance of mouse and human B cells.
Academic Article	Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies.
Academic Article	Many Achilles' heels of B and T cell tolerance.
Academic Article	SARS-CoV-2 infection relaxes peripheral B cell tolerance.
Academic Article	LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation.
Academic Article	Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells.
Academic Article	CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells.
Academic Article	Regulation of CD8 T-cell signaling, metabolism, and cytotoxic activity by extracellular lysophosphatidic acid.
Academic Article	Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity.
Academic Article	Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection.

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