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Search Results to Vernon M Holers

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Holers, Vernon

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Item Type	Name
Academic Article	Co-ligation of mouse complement receptors 1 and 2 with surface IgM rescues splenic B cells and WEHI-231 cells from anti-surface IgM-induced apoptosis.
Academic Article	Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation.
Academic Article	Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor.
Academic Article	Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice.
Academic Article	The serum resistance of malaria-infected erythrocytes.
Academic Article	Mouse complement receptors type 1 (CR1;CD35) and type 2 (CR2;CD21): expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/lpr mice.
Academic Article	Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr mice.
Academic Article	Inhibition of complement activation decreases airway inflammation and hyperresponsiveness.
Academic Article	Administration of the soluble complement inhibitor, Crry-Ig, reduces inflammation and aquaporin 4 expression in lupus cerebritis.
Academic Article	Complement activation is critical to airway hyperresponsiveness after acute ozone exposure.
Academic Article	Overexpression of complement inhibitor Crry does not prevent cryoglobulin-associated membranoproliferative glomerulonephritis.
Academic Article	Extended flexible linker structures in the complement chimaeric conjugate CR2-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.
Academic Article	The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita.
Academic Article	Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
Academic Article	Initiation of the alternative pathway of murine complement by immune complexes is dependent on N-glycans in IgG antibodies.
Academic Article	Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice.
Academic Article	Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generation in vitro.
Academic Article	Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.
Academic Article	Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Academic Article	Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice.
Academic Article	Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.
Academic Article	Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes.
Academic Article	IgM contributes to glomerular injury in FSGS.
Academic Article	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.
Academic Article	Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2.
Academic Article	Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response.
Academic Article	Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.
Academic Article	The structure of human CD23 and its interactions with IgE and CD21.
Academic Article	A prototype pathogen bound ex vivo to human erythrocyte complement receptor 1 via bispecific monoclonal antibody complexes is cleared to the liver in a mouse model.
Academic Article	Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis.
Academic Article	A site in the complement receptor 2 (CR2/CD21) silencer is necessary for lineage specific transcriptional regulation.
Academic Article	Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
Academic Article	Mice deficient in complement receptors 1 and 2 lack a tissue injury-inducing subset of the natural antibody repertoire.
Academic Article	The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.
Academic Article	Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
Academic Article	CR1/CR2 deficiency alters IgG3 autoantibody production and IgA glomerular deposition in the MRL/lpr model of SLE.
Academic Article	Association of rheumatoid arthritis treatment response and disease duration with declines in serum levels of IgM rheumatoid factor and anti-cyclic citrullinated peptide antibody.
Academic Article	A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice.
Academic Article	Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis.
Academic Article	Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA.
Academic Article	Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21).
Academic Article	Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury.
Academic Article	B cell subsets contribute to renal injury and renal protection after ischemia/reperfusion.
Academic Article	Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.
Academic Article	Oxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.
Academic Article	Treatment of refractory chronic demyelinating polyneuropathy with lymphoid irradiation.
Concept	Immunoglobulin A
Concept	Immunoglobulin Switch Region
Concept	Immunoglobulin D
Concept	Immunoglobulin E
Concept	Immunoglobulin Isotypes
Concept	Immunoglobulins
Concept	Immunoglobulin J Recombination Signal Sequence-Binding Protein
Concept	Immunoglobulin Fc Fragments
Concept	Genes, Immunoglobulin Heavy Chain
Concept	Immunoglobulin M
Concept	Genes, Immunoglobulin Light Chain
Concept	Immunoglobulin G
Academic Article	Sputum autoantibodies in patients with established rheumatoid arthritis and subjects at risk of future clinically apparent disease.
Academic Article	Deficiency of complement receptors CR2/CR1 in Cr2?/? mice reduces the extent of secondary brain damage after closed head injury.
Academic Article	A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.
Academic Article	Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.
Academic Article	Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury.
Academic Article	IgM exacerbates glomerular disease progression in complement-induced glomerulopathy.
Academic Article	Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.
Academic Article	Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement.
Academic Article	Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.
Academic Article	Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients.
Academic Article	Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
Academic Article	Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
Academic Article	Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
Academic Article	C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice.
Academic Article	A novel injury site-natural antibody targeted complement inhibitor protects against lung transplant injury.
Academic Article	Natural antibody and complement activation characterize patients with idiopathic nephrotic syndrome.
Academic Article	Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.
Academic Article	Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis.
Academic Article	Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum.
Academic Article	Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis.
Academic Article	Female but Not Male Mice Deficient in Soluble IgM Are Susceptible to Chemically Induced Glomerular Injury.

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Immunoglobulins