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Search Results to Vernon M Holers

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Holers, Vernon

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Item Type	Name
Academic Article	Expression of a soluble complement inhibitor protects transgenic mice from antibody-induced acute renal failure.
Academic Article	Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis.
Academic Article	Are anti-cyclic citrullinated peptide antibodies pathogenic in rheumatoid arthritis?
Academic Article	The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita.
Academic Article	Antibodies to citrullinated proteins: pathogenic and diagnostic significance.
Academic Article	Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
Academic Article	Complement receptor CR2/CR1 deficiency protects mice from collagen-induced arthritis and associates with reduced autoantibodies to type II collagen and citrullinated antigens.
Academic Article	Identification of undiagnosed inflammatory arthritis in a community health fair screen.
Academic Article	A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA.
Academic Article	Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis.
Academic Article	Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation.
Academic Article	Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.
Academic Article	N-a-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.
Academic Article	Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice.
Academic Article	Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.
Academic Article	Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA).
Academic Article	Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes.
Academic Article	A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis.
Academic Article	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.
Academic Article	Can we accurately predict the development of rheumatoid arthritis in the preclinical phase?
Academic Article	Anti-C1q autoantibodies amplify pathogenic complement activation in systemic lupus erythematosus.
Academic Article	Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
Academic Article	Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
Academic Article	CR1/CR2 deficiency alters IgG3 autoantibody production and IgA glomerular deposition in the MRL/lpr model of SLE.
Academic Article	Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.
Academic Article	Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA.
Academic Article	Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis.
Academic Article	Cutting edge: Complement (C3d)-linked antigens break B cell anergy.
Academic Article	Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis.
Academic Article	Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21).
Academic Article	Rheumatoid arthritis (RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent articular RA.
Academic Article	The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner.
Academic Article	Studies of Filipino patients with systemic lupus erythematosus: autoantibody profile of first-degree relatives.
Academic Article	Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?
Academic Article	Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis.
Concept	Autoantibodies
Academic Article	Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis.
Academic Article	Performance of anti-cyclic citrullinated Peptide assays differs in subjects at increased risk of rheumatoid arthritis and subjects with established disease.
Academic Article	Smoking is not associated with autoantibody production in systemic lupus erythematosus patients, unaffected first-degree relatives, nor healthy controls.
Academic Article	When and where does inflammation begin in rheumatoid arthritis?
Academic Article	Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA.
Academic Article	Sputum autoantibodies in patients with established rheumatoid arthritis and subjects at risk of future clinically apparent disease.
Academic Article	Determinants of mortality among postmenopausal women in the women's health initiative who report rheumatoid arthritis.
Academic Article	Predictive value of autoantibody testing for validating self-reported diagnoses of rheumatoid arthritis in the Women's Health Initiative.
Academic Article	Insights from populations at risk for the future development of classified rheumatoid arthritis.
Academic Article	A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.
Academic Article	Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.
Academic Article	Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative.
Academic Article	Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study.
Academic Article	Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.
Academic Article	Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis.
Academic Article	Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.
Academic Article	Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients.
Grant	Evolution of Autoimmunity in Rheumatoid Arthritis
Grant	Prevention Center U01: Early Targets for Antigen-Specific Tolerance Induction in Preclinical Rheumatoid Arthritis
Grant	Disconnecting CR2/CD21 from Its C3d Ligand to Ameliorate Lupus
Grant	Evolving Adaptive and Effector Mechanisms from Pre-RA Through Established Disease
Grant	RA-Related Autoantibodies in Healthy FDR of RA Patients
Grant	Complement in the Pathogenesis of Autoimmune Arthritis
Academic Article	Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement.
Academic Article	The association between omega-3 fatty acid biomarkers and inflammatory arthritis in an anti-citrullinated protein antibody positive population.
Academic Article	Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis.
Academic Article	Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals.
Academic Article	Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.
Academic Article	Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
Academic Article	Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
Academic Article	Unique Sj?gren's syndrome patient subsets defined by molecular features.
Academic Article	Shared and unique immune alterations in pre-clinical autoimmunity.
Academic Article	Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
Academic Article	Rheumatoid Arthritis Pathogenesis, Prediction, and Prevention: An Emerging Paradigm Shift.
Academic Article	Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting.
Grant	Complement in the Pathogenesis of Autoimmune Arthritis
Academic Article	Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes.
Academic Article	Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis.
Academic Article	Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.
Academic Article	Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis.
Academic Article	Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum.
Academic Article	Contributions of animal models to mechanistic understandings of antibody-dependent disease and roles of the amplification loop.
Academic Article	Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis.
Academic Article	Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis.
Academic Article	Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis.
Academic Article	Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis.
Academic Article	Are there causal mucosal drivers in the preclinical development of rheumatoid arthritis?

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Autoantibodies