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Search Results to Vernon M Holers

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One or more keywords matched the following items that are connected to Holers, Vernon

Item TypeName
Academic Article Complement deficiency states, disease susceptibility, and infection risk in systemic lupus erythematosus.
Academic Article Gamma-glutamyl transpeptidase is up-regulated on memory T lymphocytes.
Academic Article Arthritis critically dependent on innate immune system players.
Academic Article Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis.
Academic Article Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.
Academic Article Cigarette smoking and the risk of systemic lupus erythematosus and rheumatoid arthritis.
Academic Article Are anti-cyclic citrullinated peptide antibodies pathogenic in rheumatoid arthritis?
Academic Article Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway.
Academic Article Antibodies to citrullinated proteins: pathogenic and diagnostic significance.
Academic Article Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
Academic Article Complement receptor CR2/CR1 deficiency protects mice from collagen-induced arthritis and associates with reduced autoantibodies to type II collagen and citrullinated antigens.
Academic Article Initiation of the alternative pathway of murine complement by immune complexes is dependent on N-glycans in IgG antibodies.
Academic Article REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
Academic Article Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generation in vitro.
Academic Article Identification of undiagnosed inflammatory arthritis in a community health fair screen.
Academic Article A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA.
Academic Article Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis.
Academic Article Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation.
Academic Article Aberrant IgG galactosylation precedes disease onset, correlates with disease activity, and is prevalent in autoantibodies in rheumatoid arthritis.
Academic Article A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis.
Academic Article N-a-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.
Academic Article Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement.
Academic Article Potentially autoreactive naturally occurring transitional T3 B lymphocytes exhibit a unique signaling profile.
Academic Article Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.
Academic Article Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA).
Academic Article Rheumatoid arthritis is associated with signaling alterations in naturally occurring autoreactive B-lymphocytes.
Academic Article A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis.
Academic Article Roles of adipocytes and fibroblasts in activation of the alternative pathway of complement in inflammatory arthritis in mice.
Academic Article Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.
Academic Article Can we accurately predict the development of rheumatoid arthritis in the preclinical phase?
Academic Article Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis.
Academic Article Association of rheumatoid arthritis treatment response and disease duration with declines in serum levels of IgM rheumatoid factor and anti-cyclic citrullinated peptide antibody.
Academic Article Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.
Academic Article A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice.
Academic Article The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
Academic Article Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis.
Academic Article Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA.
Academic Article Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis.
Academic Article Intrinsic B cell hypo-responsiveness in mice prematurely expressing human CR2/CD21 during B cell development.
Academic Article Duration of preclinical rheumatoid arthritis-related autoantibody positivity increases in subjects with older age at time of disease diagnosis.
Academic Article Rheumatoid arthritis (RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent articular RA.
Academic Article Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.
Academic Article Supervised machine learning and logistic regression identifies novel epistatic risk factors with PTPN22 for rheumatoid arthritis.
Academic Article Epstein-Barr virus promotes interferon-alpha production by plasmacytoid dendritic cells.
Academic Article The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner.
Academic Article Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.
Academic Article Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?
Academic Article A novel model of rheumatoid arthritis-associated interstitial lung disease in SKG mice.
Academic Article Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis.
Academic Article Testosterone is protective in the sexually dimorphic development of arthritis and lung disease in SKG mice.
Academic Article Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.
Academic Article Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis.
Concept Arthritis, Experimental
Concept Arthritis, Rheumatoid
Concept Arthritis, Juvenile
Concept Arthritis
Academic Article Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis.
Academic Article Performance of anti-cyclic citrullinated Peptide assays differs in subjects at increased risk of rheumatoid arthritis and subjects with established disease.
Academic Article Autoimmunity to citrullinated proteins and the initiation of rheumatoid arthritis.
Academic Article When and where does inflammation begin in rheumatoid arthritis?
Academic Article Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA.
Academic Article Sputum autoantibodies in patients with established rheumatoid arthritis and subjects at risk of future clinically apparent disease.
Academic Article Rheumatoid arthritis in the Women's Health Initiative: methods and baseline evaluation.
Academic Article Determinants of mortality among postmenopausal women in the women's health initiative who report rheumatoid arthritis.
Academic Article Predictive value of autoantibody testing for validating self-reported diagnoses of rheumatoid arthritis in the Women's Health Initiative.
Academic Article Essential role for the lectin pathway in collagen antibody-induced arthritis revealed through use of adenovirus programming complement inhibitor MAp44 expression.
Academic Article Insights from populations at risk for the future development of classified rheumatoid arthritis.
Academic Article A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.
Academic Article An Internet-based technique for the identification of persons with symptoms of inflammatory polyarthritis of less than 12 weeks.
Academic Article Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.
Academic Article A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA.
Academic Article Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative.
Academic Article Predicting and preventing the development of rheumatoid arthritis.
Academic Article Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study.
Academic Article Targeting mechanisms at sites of complement activation for imaging and therapy.
Academic Article Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.
Academic Article Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing.
Academic Article A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22.
Academic Article Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis.
Academic Article Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.
Academic Article Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients.
Academic Article Editorial: Prevention of Rheumatoid Arthritis: Now Is the Time, but How to Proceed?
Grant Colorado Autoimmunity Center of Excellence
Grant Evolution of Autoimmunity in Rheumatoid Arthritis
Grant Prevention Center U01: Early Targets for Antigen-Specific Tolerance Induction in Preclinical Rheumatoid Arthritis
Grant Evolving Adaptive and Effector Mechanisms from Pre-RA Through Established Disease
Grant RA-Related Autoantibodies in Healthy FDR of RA Patients
Grant Complement in the Pathogenesis of Autoimmune Arthritis
Grant Denver Autoimmunity Center of Excellence
Academic Article Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
Academic Article Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study.
Academic Article The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune Diseases.
Academic Article The association between omega-3 fatty acid biomarkers and inflammatory arthritis in an anti-citrullinated protein antibody positive population.
Academic Article Association of Antibodies to Citrullinated Protein Antigens with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis.
Academic Article Genetic and environmental risk factors for rheumatoid arthritis.
Academic Article Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis.
Academic Article Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals.
Academic Article Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more rapid progression from preclinical to clinical rheumatoid arthritis.
Academic Article Complement in the Initiation and Evolution of Rheumatoid Arthritis.
Academic Article Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients.
Academic Article Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
Academic Article Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to?destruction.
Academic Article Targeting of Liver Mannan-Binding Lectin-Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis.
Academic Article Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
Academic Article Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
Academic Article Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.
Academic Article Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.
Academic Article The Natural History of Rheumatoid Arthritis.
Academic Article Nomenclature for the Phases of the Development of Rheumatoid Arthritis.
Academic Article Complement and its environmental determinants in the progression of human rheumatoid arthritis.
Academic Article Timing of Elevations of Autoantibody Isotypes Prior to Diagnosis of Rheumatoid Arthritis.
Academic Article Perceived Stress and Inflammatory Arthritis: A Prospective Investigation in the Studies of the Etiologies of Rheumatoid Arthritis Cohort.
Academic Article Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D.
Academic Article Heightened Levels of Antimicrobial Response Factors in Patients With Rheumatoid Arthritis.
Academic Article Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF.
Academic Article Rheumatoid Arthritis Pathogenesis, Prediction, and Prevention: An Emerging Paradigm Shift.
Academic Article Methotrexate and rheumatoid arthritis associated interstitial lung disease.
Academic Article Challenges and Opportunities: Using Omics to Generate Testable Insights Into Pathogenic Mechanisms in Preclinical Seropositive Rheumatoid Arthritis.
Academic Article Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting.
Grant Complement in the Pathogenesis of Autoimmune Arthritis
Academic Article C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice.
Academic Article Association of Lipid Mediators With Development of Future Incident Inflammatory Arthritis in an Anti-Citrullinated Protein Antibody-Positive Population.
Academic Article Subjects at-risk for future development of rheumatoid arthritis demonstrate a PAD4-and TLR-dependent enhanced histone H3 citrullination and proinflammatory cytokine production in CD14hi monocytes.
Academic Article Publisher Correction: Biological classification of childhood arthritis: roadmap to a molecular nomenclature.
Academic Article Biological classification of childhood arthritis: roadmap to a molecular nomenclature.
Academic Article Individuals at risk for rheumatoid arthritis harbor differential intestinal bacteriophage communities with distinct metabolic potential.
Academic Article Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis.
Academic Article EULAR points to consider for conducting clinical trials and observational studies in individuals at risk of rheumatoid arthritis.
Academic Article Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis.
Academic Article Combinations of Anticyclic Citrullinated Protein Antibody, Rheumatoid Factor, and Serum Calprotectin Positivity Are Associated With the Diagnosis of Rheumatoid Arthritis Within 3 Years.
Academic Article Evaluating associations of joint swelling, joint stiffness and joint pain with physical activity in first-degree relatives of patients with rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA), a prospective cohort study.
Academic Article Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.
Grant Center for Mucosal Immunobiology and Rheumatic Disease Pathogenesis
Academic Article Clinical Academic Rheumatology: Still Getting More Than You Pay For.
Academic Article Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features.
Academic Article Longitudinal Immune Cell Profiling in Patients With Early Systemic Lupus Erythematosus.
Academic Article Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.
Academic Article Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis.
Academic Article Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum.
Academic Article Mechanism-driven strategies for prevention of rheumatoid arthritis.
Academic Article Reply.
Academic Article Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis.
Academic Article Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis.
Academic Article Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis.
Academic Article Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium.
Academic Article 3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity.
Academic Article Associations Between Rheumatoid Arthritis Clinical Factors and Synovial Cell Types and States.
Academic Article Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
Academic Article Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis.
Academic Article Are there causal mucosal drivers in the preclinical development of rheumatoid arthritis?

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