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Search Results to Vernon M Holers

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One or more keywords matched the following items that are connected to Holers, Vernon

Item TypeName
Academic Article CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21.
Academic Article Moesin, and not the murine functional homologue (Crry/p65) of human membrane cofactor protein (CD46), is involved in the entry of measles virus (strain Edmonston) into susceptible murine cell lines.
Academic Article Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.
Academic Article Co-ligation of mouse complement receptors 1 and 2 with surface IgM rescues splenic B cells and WEHI-231 cells from anti-surface IgM-induced apoptosis.
Academic Article Expression and function of membrane regulators of complement on rat astrocytes in culture.
Academic Article Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation.
Academic Article Characterization of C3-binding proteins on mouse neutrophils and platelets.
Academic Article Cross-linking CD21/CD35 or CD19 increases both B7-1 and B7-2 expression on murine splenic B cells.
Academic Article Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor.
Academic Article Macrophage-colony-stimulating factor regulates expression of the integrins alpha 4 beta 1 and alpha 5 beta 1 by murine bone marrow macrophages.
Academic Article Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3. An initial model of ligand interaction with two linked short consensus repeat modules.
Academic Article Gamma-glutamyl transpeptidase is up-regulated on memory T lymphocytes.
Academic Article Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury.
Academic Article Activation of complement mediates antiphospholipid antibody-induced pregnancy loss.
Academic Article A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
Academic Article Anti-phospholipid antibodies restore mesenteric ischemia/reperfusion-induced injury in complement receptor 2/complement receptor 1-deficient mice.
Academic Article Antibodies against cyclic citrullinated peptide are associated with HLA-DR4 in simplex and multiplex polyarticular-onset juvenile rheumatoid arthritis.
Academic Article Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury.
Academic Article Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus.
Academic Article Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.
Academic Article Are anti-cyclic citrullinated peptide antibodies pathogenic in rheumatoid arthritis?
Academic Article Role for CD21 in the establishment of an extracellular HIV reservoir in lymphoid tissues.
Academic Article Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway.
Academic Article Complement is an essential component of the immune response to adeno-associated virus vectors.
Academic Article Antibodies to citrullinated proteins: pathogenic and diagnostic significance.
Academic Article Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.
Academic Article The spectrum of complement alternative pathway-mediated diseases.
Academic Article Initiation of the alternative pathway of murine complement by immune complexes is dependent on N-glycans in IgG antibodies.
Academic Article Complement activation pathways in murine immune complex-induced arthritis and in C3a and C5a generation in vitro.
Academic Article Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Academic Article Complement C3 activation is required for antiphospholipid antibody-induced fetal loss.
Academic Article Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice.
Academic Article Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.
Academic Article Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.
Academic Article IgM contributes to glomerular injury in FSGS.
Academic Article Analysis of C3b/C3d binding sites and factor I cofactor regions within mouse complement receptors 1 and 2.
Academic Article A prototype pathogen bound ex vivo to human erythrocyte complement receptor 1 via bispecific monoclonal antibody complexes is cleared to the liver in a mouse model.
Academic Article Expression of human complement receptor 2 (CR2, CD21) in Cr2-/- mice restores humoral immune function.
Academic Article Epitope mapping using the X-ray crystallographic structure of complement receptor type 2 (CR2)/CD21: identification of a highly inhibitory monoclonal antibody that directly recognizes the CR2-C3d interface.
Academic Article Structural requirements for C3d,g/Epstein-Barr virus receptor (CR2/CD21) ligand binding, internalization, and viral infection.
Academic Article The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
Academic Article Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.
Academic Article Complement receptor 2, natural antibodies and innate immunity: Inter-relationships in B cell selection and activation.
Academic Article Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis.
Academic Article Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice.
Academic Article Isolating the Epstein-Barr virus gp350/220 binding site on complement receptor type 2 (CR2/CD21).
Academic Article Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury.
Academic Article Human complement receptor type 2 (CR2/CD21) transgenic mice provide an in vivo model to study immunoregulatory effects of receptor antagonists.
Academic Article Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.
Academic Article Human peripheral blood monocytes display surface antigens recognized by monoclonal antinuclear antibodies.
Academic Article Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Academic Article Detection of complement activation using monoclonal antibodies against C3d.
Academic Article Structural and functional studies on the human C3b/C4b receptor (CR1) purified by affinity chromatography using a monoclonal antibody.
Concept Antibodies, Anti-Idiotypic
Concept Antibodies, Anticardiolipin
Concept Antibodies, Monoclonal
Concept Antibodies, Blocking
Concept Antibodies, Antinuclear
Concept Antibodies, Antiphospholipid
Concept Antibodies
Concept Antibodies, Viral
Concept Single-Chain Antibodies
Concept Antibodies, Bacterial
Concept Antibodies, Heterophile
Concept Antibodies, Bispecific
Academic Article Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis.
Academic Article Smoking is not associated with autoantibody production in systemic lupus erythematosus patients, unaffected first-degree relatives, nor healthy controls.
Academic Article Rheumatoid arthritis in the Women's Health Initiative: methods and baseline evaluation.
Academic Article Predictive value of autoantibody testing for validating self-reported diagnoses of rheumatoid arthritis in the Women's Health Initiative.
Academic Article A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.
Academic Article Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.
Academic Article Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury.
Academic Article A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA.
Academic Article Targeting mechanisms at sites of complement activation for imaging and therapy.
Academic Article A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22.
Academic Article Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients.
Grant ACR Basic Research Conference
Grant Mouse Membrane RCA Proteins in the Immune Response
Grant Disconnecting CR2/CD21 from Its C3d Ligand to Ameliorate Lupus
Grant RA-Related Autoantibodies in Healthy FDR of RA Patients
Grant Complement in the Pathogenesis of Autoimmune Arthritis
Academic Article Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement.
Academic Article A novel C3d-containing oligomeric vaccine provides insight into the viability of testing human C3d-based vaccines in mice.
Academic Article The association between omega-3 fatty acid biomarkers and inflammatory arthritis in an anti-citrullinated protein antibody positive population.
Academic Article Association of Antibodies to Citrullinated Protein Antigens with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis.
Academic Article Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals.
Academic Article Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more rapid progression from preclinical to clinical rheumatoid arthritis.
Academic Article Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients.
Academic Article Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to?destruction.
Concept Anti-Citrullinated Protein Antibodies
Concept Antibodies, Monoclonal, Murine-Derived
Concept Antibodies, Monoclonal, Humanized
Academic Article Anticyclic Citrullinated Peptide Antibodies 3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
Academic Article Complement and its environmental determinants in the progression of human rheumatoid arthritis.
Academic Article Timing of Elevations of Autoantibody Isotypes Prior to Diagnosis of Rheumatoid Arthritis.
Academic Article Unique Sj?gren's syndrome patient subsets defined by molecular features.
Academic Article Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
Academic Article Heightened Levels of Antimicrobial Response Factors in Patients With Rheumatoid Arthritis.
Academic Article Rheumatoid Arthritis Pathogenesis, Prediction, and Prevention: An Emerging Paradigm Shift.
Academic Article Factors associated with progression to inflammatory arthritis in first-degree relatives of individuals with RA following autoantibody positive screening in a non-clinical setting.
Academic Article C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice.
Academic Article Association of Lipid Mediators With Development of Future Incident Inflammatory Arthritis in an Anti-Citrullinated Protein Antibody-Positive Population.
Academic Article Individuals at risk for rheumatoid arthritis harbor differential intestinal bacteriophage communities with distinct metabolic potential.
Academic Article Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis.
Academic Article Association of Sputum Neutrophil Extracellular Trap Subsets With IgA Anti-Citrullinated Protein Antibodies in Subjects at Risk for Rheumatoid Arthritis.
Academic Article Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.
Academic Article Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Academic Article Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis.
Academic Article Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum.
Academic Article Association of Antibodies to Prevotella copri in Anti-Cyclic Citrullinated Peptide-Positive Individuals At Risk of Developing Rheumatoid Arthritis and in Patients With Early or Established Rheumatoid Arthritis.
Academic Article Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe.
Academic Article Are there causal mucosal drivers in the preclinical development of rheumatoid arthritis?

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