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Search Results to Rajesh Agarwal

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Agarwal, Rajesh

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Item Type	Name
Academic Article	Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis.
Academic Article	Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels.
Academic Article	Flavonoid antioxidant silymarin and skin cancer.
Academic Article	Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis.
Academic Article	Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
Academic Article	Tumor angiogenesis: a potential target in cancer control by phytochemicals.
Academic Article	Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention.
Academic Article	Inhibition of NF-kappaB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells.
Academic Article	Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.
Academic Article	Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis.
Academic Article	Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.
Academic Article	Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin- and carboplatin-induced growth inhibition and apoptotic death.
Academic Article	Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells.
Academic Article	Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
Academic Article	Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages.
Academic Article	In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor.
Academic Article	Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells.
Academic Article	Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy.
Academic Article	Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.
Academic Article	A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer.
Academic Article	Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
Academic Article	Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells.
Academic Article	Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
Academic Article	Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate.
Academic Article	Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells.
Academic Article	Prostate cancer and inositol hexaphosphate: efficacy and mechanisms.
Academic Article	Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
Academic Article	Silibinin efficacy against human hepatocellular carcinoma.
Academic Article	Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
Academic Article	Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells.
Academic Article	Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
Academic Article	Mechanisms of action of novel agents for prostate cancer chemoprevention.
Academic Article	Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells.
Academic Article	Fractionation of high molecular weight tannins in grape seed extract and identification of procyanidin B2-3,3'-di-O-gallate as a major active constituent causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
Academic Article	Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.
Academic Article	Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice.
Academic Article	Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells.
Academic Article	Chemopreventive efficacy of silymarin in skin and prostate cancer.
Academic Article	p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.
Academic Article	Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention.
Academic Article	Inducible nitric oxide synthase-vascular endothelial growth factor axis: a potential target to inhibit tumor angiogenesis by dietary agents.
Academic Article	Transcription factors: molecular targets for prostate cancer intervention by phytochemicals.
Academic Article	Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.
Academic Article	Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms.
Academic Article	Silibinin impairs constitutively active TGFalpha-EGFR autocrine loop in advanced human prostate carcinoma cells.
Academic Article	New combination therapies with cell-cycle agents.
Academic Article	Photoprotective effects of bucillamine against UV-induced damage in an SKH-1 hairless mouse model.
Academic Article	Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
Academic Article	Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.
Academic Article	Multitargeted therapy of cancer by silymarin.
Academic Article	Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice.
Academic Article	Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.
Academic Article	Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.
Academic Article	Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos.
Academic Article	p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer.
Academic Article	Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice.
Academic Article	Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice.
Academic Article	Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells.
Academic Article	Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft.
Academic Article	Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products.
Academic Article	Silibinin suppresses spontaneous tumorigenesis in APC min/+ mouse model by modulating beta-catenin pathway.
Academic Article	Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators.
Academic Article	Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice.
Academic Article	Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target.
Academic Article	Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
Academic Article	Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.
Academic Article	Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
Academic Article	Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules.
Academic Article	Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer.
Academic Article	Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.
Academic Article	Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells.
Academic Article	Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells.
Academic Article	Silibinin modulates TNF-a and IFN-? mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells.
Academic Article	Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.
Academic Article	Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angioprevention.
Academic Article	Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45a-dependent manner.
Academic Article	Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells.
Academic Article	Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling.
Academic Article	Inositol hexaphosphate inhibits tumor growth, vascularity, and metabolism in TRAMP mice: a multiparametric magnetic resonance study.
Academic Article	Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship.
Academic Article	Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction.
Academic Article	Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries.
Academic Article	Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells.
Academic Article	Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells.
Academic Article	Inositol hexaphosphate inhibits constitutive activation of NF- kappa B in androgen-independent human prostate carcinoma DU145 cells.
Academic Article	Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3.
Academic Article	Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells.
Academic Article	Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells.
Academic Article	Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance.
Academic Article	A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
Academic Article	Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice.
Academic Article	Effect of silibinin on the growth and progression of primary lung tumors in mice.
Academic Article	Silymarin and epithelial cancer chemoprevention: how close we are to bedside?
Academic Article	Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells.
Academic Article	Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells.
Academic Article	Prostate cancer prevention by silibinin.
Academic Article	Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release.
Academic Article	Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin.
Academic Article	Mechanisms and preclinical efficacy of silibinin in preventing skin cancer.
Academic Article	Natural flavonoids targeting deregulated cell cycle progression in cancer cells.
Academic Article	Prostate cancer chemoprevention by silibinin: bench to bedside.
Academic Article	Silibinin inhibits UVB- and epidermal growth factor-induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-kappaB in mouse epidermal JB6 cells.
Academic Article	Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation.
Academic Article	Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice.
Academic Article	Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.
Academic Article	Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype.
Academic Article	A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients.
Academic Article	Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin.
Academic Article	Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells.
Academic Article	Kava, a tonic for relieving the irrational development of natural preventive agents.
Academic Article	Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.
Academic Article	Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.
Academic Article	Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells.
Academic Article	Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice.
Academic Article	Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft.
Academic Article	Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships.
Academic Article	A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer.
Academic Article	Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
Academic Article	Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin.
Academic Article	Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells.
Academic Article	Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization.
Academic Article	Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells.
Academic Article	Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice.
Academic Article	Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
Academic Article	Silibinin feeding alters the metabolic profile in TRAMP prostatic tumors: 1H-NMRS-based metabolomics study.
Academic Article	Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells.
Academic Article	Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
Academic Article	Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-?B, and androgen receptor signaling.
Academic Article	Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models.
Academic Article	Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-?B signaling.
Academic Article	Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways.
Academic Article	Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.
Academic Article	Deletion of p21/Cdkn1a confers protective effect against prostate tumorigenesis in transgenic adenocarcinoma of the mouse prostate model.
Academic Article	Chemopreventive and anti-cancer efficacy of silibinin against growth and progression of lung cancer.
Academic Article	Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth.
Academic Article	Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma.
Academic Article	Emerging trends in cancer research: prevention and therapeutics. Preface.
Academic Article	Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells.
Academic Article	Chemopreventive properties of dietary rice bran: current status and future prospects.
Academic Article	Silibinin synergizes with histone deacetylase and DNA methyltransferase inhibitors in upregulating E-cadherin expression together with inhibition of migration and invasion of human non-small cell lung cancer cells.
Academic Article	Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer.
Academic Article	Identifying molecular targets of lifestyle modifications in colon cancer prevention.
Academic Article	Promise and potential of silibinin in colorectal cancer management: what patterns can be seen?
Concept	Thyroid Neoplasms
Concept	Mammary Neoplasms, Experimental
Concept	Tumor Burden
Concept	Brain Neoplasms
Concept	Lung Neoplasms
Concept	Tumor Suppressor Protein p53
Concept	Prostatic Neoplasms
Concept	Neoplasm Metastasis
Concept	Prostatic Intraepithelial Neoplasia
Concept	Urinary Bladder Neoplasms
Concept	DNA, Neoplasm
Concept	Biomarkers, Tumor
Concept	Antigens, Neoplasm
Concept	Ovarian Neoplasms
Concept	Colorectal Neoplasms
Concept	Pancreatic Neoplasms
Concept	Neoplasm Proteins
Concept	Neoplasm Staging
Concept	Neoplasms, Radiation-Induced
Concept	Kidney Neoplasms
Concept	Drug Resistance, Neoplasm
Concept	Neoplasm Transplantation
Concept	Mouth Neoplasms
Concept	Breast Neoplasms
Concept	Stomach Neoplasms
Concept	Tumor Stem Cell Assay
Concept	Tumor Cells, Cultured
Concept	Head and Neck Neoplasms
Concept	Neoplasms, Hormone-Dependent
Concept	Tumor Necrosis Factor-alpha
Concept	Neoplasms
Concept	Skin Neoplasms
Concept	Tongue Neoplasms
Concept	Colonic Neoplasms
Concept	Cell Line, Tumor
Concept	Tumor Suppressor Proteins
Concept	Intestinal Neoplasms
Concept	Liver Neoplasms
Concept	Uterine Cervical Neoplasms
Concept	Neoplasm Invasiveness
Academic Article	Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells.
Academic Article	Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy.
Academic Article	Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation.
Academic Article	Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.
Academic Article	Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression.
Academic Article	Poly[3-(3, 4-dihydroxyphenyl) glyceric acid] from Comfrey exerts anti-cancer efficacy against human prostate cancer via targeting androgen receptor, cell cycle arrest and apoptosis.
Academic Article	Role of oxidative stress in cytotoxicity of grape seed extract in human bladder cancer cells.
Academic Article	Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-?B, and AP-1 activation in RAW264.7 cells.
Academic Article	The strategies to control prostate cancer by chemoprevention approaches.
Academic Article	SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin.
Academic Article	Procyanidin B2 3,3(?)-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-?B, Stat3, and AP1 transcription factors.
Academic Article	Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.
Academic Article	Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy.
Academic Article	Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.
Academic Article	Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals.
Academic Article	Nuclear factor ?B-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8.
Academic Article	In vitro and in vivo anticancer efficacy of silibinin against human pancreatic cancer BxPC-3 and PANC-1 cells.
Academic Article	Differential effects of grape seed extract against human colorectal cancer cell lines: the intricate role of death receptors and mitochondria.
Academic Article	Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells.
Academic Article	Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.
Academic Article	A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma.
Academic Article	Procyanidin B2 3,3?-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways.
Academic Article	Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells.
Academic Article	Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses.
Academic Article	Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling.
Academic Article	Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators.
Academic Article	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.
Academic Article	Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts.
Academic Article	Silibinin prevents prostate cancer cell-mediated differentiation of na?ve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF ?2.
Academic Article	Chemopreventive opportunities to control basal cell carcinoma: Current perspectives.
Academic Article	Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation.
Academic Article	Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.
Academic Article	Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.
Academic Article	Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts.
Academic Article	Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling.
Academic Article	Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.
Academic Article	Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity.
Academic Article	Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus.
Academic Article	Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment.
Academic Article	A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells.
Academic Article	Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy.
Academic Article	Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis.
Academic Article	Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy.
Academic Article	Natural products and colon cancer: current status and future prospects.
Academic Article	Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells.
Academic Article	Silibinin and colorectal cancer chemoprevention: a comprehensive review on mechanisms and efficacy.
Academic Article	Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells.
Academic Article	Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death.
Academic Article	ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway.
Academic Article	An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin.
Academic Article	Silibinin inhibits hypoxia-induced HIF-1a-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics.
Academic Article	Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor-Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling.
Academic Article	Mechanisms and Drug Targets for Pancreatic Cancer Chemoprevention.
Grant	CANCER CHEMOPREVENTION BY SILYMARIN
Grant	RECEPTOR SIGNALING, PHYTIC ACID AND PROSTATE CANCER
Grant	Skin Cancer Chemoprevention by Silibinin: Mechanisms and Efficacy
Grant	CANCER CHEMOPREVENTION BY SILYMARIN
Grant	Prostate Cancer Prevention and Treatment by Silibinin
Grant	Angioprevention of Lung Tumorigenesis by Silibinin
Grant	Prostate Cancer Chemoprevention by Inositol Hexaphosphate Efficacy and Mechanism
Grant	Molecular mechanism of bitter melon juice efficacy against pancreatic cancer.
Grant	Bladder Cancer Prevention by Silibinin
Grant	Colon Cancer Chemoprevention by Flavonoid Silibinin
Academic Article	Nintedanib antiangiogenic inhibitor effectiveness in delaying adenocarcinoma progression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP).
Academic Article	Acacetin enhances the therapeutic efficacy of doxorubicin in non-small-cell lung carcinoma cells.
Academic Article	Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma.
Academic Article	Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK.
Academic Article	Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of ?-catenin in colon cancer stem cells.
Academic Article	Exosomal microRNA profiling to identify hypoxia-related biomarkers in prostate cancer.
Academic Article	Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells.
Academic Article	Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells.
Academic Article	Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators.
Academic Article	Nutraceuticals in prostate cancer therapeutic strategies and their neo-adjuvant use in diverse populations.
Academic Article	A novel approach to target hypoxic cancer cells via combining ?-oxidation inhibitor etomoxir with radiation.
Academic Article	Silibinin phosphodiester glyco-conjugates: Synthesis, redox behaviour and biological investigations.
Academic Article	Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients.
Academic Article	Differential effect of grape seed extract and its active constituent procyanidin B2 3,3?-di-O-gallate against prostate cancer stem cells.
Academic Article	Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma.
Concept	Tumor Microenvironment
Concept	Tumor Hypoxia
Concept	Tumor Protein p73
Concept	Prostatic Neoplasms, Castration-Resistant
Concept	Neoplasm Grading
Academic Article	Bitter melon juice-intake modulates glucose metabolism and lactate efflux in tumors in its efficacy against pancreatic cancer.
Academic Article	Antiangiogenic therapy with Nintedanib affects hypoxia, angiogenesis and apoptosis in the ventral prostate of TRAMP animals.
Academic Article	Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells.
Academic Article	Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches.
Academic Article	Silibinin and non-melanoma skin cancers.
Academic Article	Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors.
Academic Article	Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity.
Academic Article	Solid-phase synthesis of curcumin mimics and their anticancer activity against human pancreatic, prostate, and colorectal cancer cell lines.
Academic Article	Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer.
Academic Article	Stage-specific differential expression of zinc transporter SLC30A and SLC39A family proteins during prostate tumorigenesis.
Academic Article	Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/- mice.
Academic Article	Characterization of stage-specific tumor progression in TMPRSS2-ERG (fusion)-driven and non-fusion-driven prostate cancer in GEM models.
Academic Article	Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model.
Academic Article	Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells.
Academic Article	Integrated Microbiota and Metabolite Changes following Rice Bran Intake during Murine Inflammatory Colitis-Associated Colon Cancer and in Colorectal Cancer Survivors.
Academic Article	Differential Effect of Non-Steroidal Anti-Inflammatory Drugs Aspirin and Naproxen against TMPRSS2-ERG (Fusion)-Driven and Non-Fusion-Driven Prostate Cancer.
Academic Article	Phytochemicals as Immunomodulatory Molecules in Cancer Therapeutics.

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