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Search Results to Daniel Aaron Pollyea

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Pollyea, Daniel

One or more keywords matched the following items that are connected to Pollyea, Daniel

Item Type	Name
Academic Article	Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.
Academic Article	Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia.
Academic Article	2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
Academic Article	Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia.
Academic Article	Ponatinib for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.
Academic Article	Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
Academic Article	Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation.
Academic Article	Second-line mitoxantrone, etoposide, and cytarabine for acute myeloid leukemia: a single-center experience.
Concept	Leukemia, Myeloid
Concept	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Concept	Leukemia, Myeloid, Acute
Concept	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Academic Article	Omacetaxine mepesuccinate for the treatment of chronic myeloid leukemia.
Academic Article	Expert insights into the contemporary management of older adults with acute myeloid leukemia.
Academic Article	Aldehyde dehydrogenases in acute myeloid leukemia.
Academic Article	Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.
Academic Article	Targeting acute myeloid leukemia stem cells: a review and principles for the development of clinical trials.
Academic Article	The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis.
Academic Article	Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations.
Academic Article	Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.
Academic Article	MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
Academic Article	Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies.
Academic Article	Connect MDS/AML: design of the myelodysplastic syndromes and acute myeloid leukemia disease registry, a prospective observational cohort study.
Academic Article	Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.
Academic Article	Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia.
Academic Article	Isocitrate dehydrogenase mutations in myeloid malignancies.
Academic Article	ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
Academic Article	Rational design of a parthenolide-based drug regimen that selectively eradicates acute myelogenous leukemia stem cells.
Academic Article	Therapeutic targeting of acute myeloid leukemia stem cells.
Academic Article	Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1.
Academic Article	Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia.
Academic Article	Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia.
Academic Article	Acute Myeloid Leukemia, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies.
Academic Article	Midostaurin: A New Oral Agent Targeting FMS-Like Tyrosine Kinase 3-Mutant Acute Myeloid Leukemia.
Academic Article	Randomized study of continuous high-dose lenalidomide, sequential azacitidine and lenalidomide, or azacitidine in persons 65 years and over with newly-diagnosed acute myeloid leukemia.
Academic Article	Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study.
Academic Article	Phase Ib Study of Glasdegib, a Hedgehog Pathway Inhibitor, in Combination with Standard Chemotherapy in Patients with AML or High-Risk MDS.
Academic Article	Thiotepa-Based Intensified Reduced-Intensity Conditioning Adult Double-Unit Cord Blood Hematopoietic Stem Cell Transplantation Results in Decreased Relapse Rate and Improved Survival Compared with Transplantation Following Standard Reduced-Intensity Conditioning: A Retrospective Cohort Comparison.
Academic Article	Targeting the IDH2 Pathway in Acute Myeloid Leukemia.
Academic Article	Enasidenib for the treatment of acute myeloid leukemia.
Academic Article	Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.
Academic Article	AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.
Academic Article	Shutting Down Acute Myeloid Leukemia and Myelodysplastic Syndrome with BCL-2 Family Protein Inhibition.
Academic Article	Glasdegib in combination with cytarabine and daunorubicin in patients with AML or high-risk MDS: Phase 2 study results.
Academic Article	Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes.
Academic Article	Functional genomic landscape of acute myeloid leukaemia.
Academic Article	Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia.
Academic Article	Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.
Academic Article	Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.
Academic Article	Which novel agents for acute myeloid leukemia are likely to change practice?
Academic Article	Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib.
Academic Article	New drugs for acute myeloid leukemia inspired by genomics and when to use them.
Academic Article	Why are hypomethylating agents or low-dose cytarabine and venetoclax so effective?
Academic Article	Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome.
Academic Article	Optimizing survival outcomes with post-remission therapy in acute myeloid leukemia.
Academic Article	Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia.
Academic Article	Sequential azacitidine and lenalidomide for patients with relapsed and refractory acute myeloid leukemia: Clinical results and predictive modeling using computational analysis.
Academic Article	Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.
Academic Article	Acute myeloid leukemia drug development in the post-venetoclax era.
Academic Article	Acute Myeloid Leukemia, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	How we use venetoclax with hypomethylating agents for the treatment of newly diagnosed patients with acute myeloid leukemia.
Academic Article	Real-world experience of venetoclax with azacitidine for untreated patients with acute myeloid leukemia.
Academic Article	Therapeutic Advances in First-Line Management of Acute Myeloid Leukemia.
Academic Article	Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
Academic Article	Hypomethylating agents with venetoclax: have we discovered the holy grail?
Academic Article	Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.
Academic Article	Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study.
Academic Article	Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.
Academic Article	Venetoclax with azacitidine for two younger Jehovah's Witness patients with high risk acute myeloid leukemia.
Academic Article	Glasdegib as maintenance therapy for patients with AML and MDS patients at high risk for postallogeneic stem cell transplant relapse.
Academic Article	Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy.
Academic Article	Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.
Academic Article	Venetoclax in AML: Where We Are and Where We Are Headed.
Academic Article	Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.
Academic Article	Venetoclax with azacitidine or decitabine in patients with newly diagnosed acute myeloid leukemia: Long term follow-up from a phase 1b study.
Academic Article	Complete, yet partial: the benefits of complete response with partial haematological recovery as an endpoint in acute myeloid leukaemia clinical trials.
Academic Article	The propriety of upgrading responses to venetoclax?+?azacitidine in newly diagnosed patients with acute myeloid leukemia.
Academic Article	New directions for emerging therapies in acute myeloid leukemia: the next chapter.
Academic Article	NCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021.
Academic Article	The complete story of less than complete responses: The evolution and application of acute myeloid leukemia clinical responses.
Academic Article	A Phase I dose-escalation study of DCLL9718S, an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1) in patients with acute myeloid leukemia.
Academic Article	Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells.
Academic Article	Optimizing Risk Stratification in Acute Myeloid Leukemia: Dynamic Models for a Dynamic Therapeutic Landscape.
Academic Article	Venetoclax and azacitidine compared with induction chemotherapy for newly diagnosed patients with acute myeloid leukemia.
Academic Article	Venetoclax and azacitidine followed by allogeneic transplant results in excellent outcomes and may improve outcomes versus maintenance therapy among newly diagnosed AML patients older than 60.
Academic Article	SOHO State of the Art Updates and Next Questions: The Past, Present and Future of Venetoclax-Based Therapies in AML.
Academic Article	Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML.
Academic Article	The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation.
Academic Article	Project 2025: Proposals for the Continued Success of Drug Development in Acute Myeloid Leukemia.
Academic Article	Beyond Survival: The US Food and Drug Administration Confirms Surrogate End Points for Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Intensive Chemotherapy.
Academic Article	Impact of Venetoclax and Azacitidine in Treatment-Na?ve Patients with Acute Myeloid Leukemia and IDH1/2 Mutations.
Academic Article	Treatment-free remission after ceasing venetoclax-based therapy in patients with acute myeloid leukemia.
Academic Article	21q22 amplification detection in three patients with acute myeloid leukemia: cytogenomic profiling and literature review.
Academic Article	Diagnostic and molecular testing patterns in patients with newly diagnosed acute myeloid leukemia in the Connect? MDS/AML Disease Registry.
Academic Article	Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Academic Article	Outcomes Are Similar After Allogeneic Hematopoietic Stem Cell Transplant for Newly Diagnosed Acute Myeloid Leukemia Patients who Received Venetoclax?+?Azacitidine Versus Intensive Chemotherapy.
Academic Article	A phase 1b study of venetoclax and azacitidine combination in patients with relapsed or refractory myelodysplastic syndromes.
Academic Article	Lower intensity regimens for acute myeloid leukemia: opportunities and challenges.
Academic Article	Top advances of the year: Leukemia.
Academic Article	Recent progress in acute leukemia and myelodysplasia.
Academic Article	Outcomes in Patients with Poor-Risk Cytogenetics with or without TP53 Mutations Treated with Venetoclax and Azacitidine.
Academic Article	Venetoclax plus azacitidine compared with intensive chemotherapy as induction for patients with acute myeloid leukemia: retrospective analysis of an electronic medical record database in the United States.
Academic Article	Incidence of Invasive Fungal Infections in Patients With Previously Untreated Acute Myeloid Leukemia Receiving Venetoclax and Azacitidine.
Academic Article	Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial.
Academic Article	A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies.
Academic Article	Venetoclax response prediction in acute myeloid leukemia: are we Finnish-ed with uncertainty?
Academic Article	Magrolimab in Combination With Azacitidine in Patients With Higher-Risk Myelodysplastic Syndromes: Final Results of a Phase Ib Study.
Academic Article	Higher-dose venetoclax with measurable residual disease-guided azacitidine discontinuation in newly diagnosed acute myeloid leukemia.
Academic Article	Transplantation Referral Patterns for Patients with Newly Diagnosed Higher-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia at Academic and Community Sites in the Connect? Myeloid Disease Registry: Potential Barriers to Care.
Academic Article	Venetoclax is safe and tolerable as post-transplant maintenance therapy for AML patients at high risk for relapse.
Academic Article	Acute Myeloid Leukemia, Version 3.2023, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	Venetoclax-based salvage therapy for adult patients with relapsed/refractory acute lymphoblastic leukemia.
Academic Article	Outcomes with molecularly targeted agents as salvage therapy following frontline venetoclax + hypomethylating agent in adults with acute myeloid leukemia: A multicenter retrospective analysis.
Academic Article	Correction to: Venetoclax plus azacitidine compared with intensive chemotherapy as induction for patients with acute myeloid leukemia: retrospective analysis of an electronic medical record database in the United States.
Academic Article	Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis.
Academic Article	Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium.
Academic Article	Multi-gene measurable residual disease assessed by digital polymerase chain reaction has clinical and biological utility in acute myeloid leukemia patients receiving venetoclax/azacitidine.
Academic Article	Progress and challenges in the acute leukemia field.

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Leukemia Myeloid