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Search Results to Theodore W Randolph

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Randolph, Theodore

One or more keywords matched the following items that are connected to Randolph, Theodore

Item Type	Name
Academic Article	Counteracting effects of renal solutes on amyloid fibril formation by immunoglobulin light chains.
Academic Article	Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation.
Academic Article	IgG particle formation during filling pump operation: a case study of heterogeneous nucleation on stainless steel nanoparticles.
Academic Article	Physical instability of a therapeutic Fc fusion protein: domain contributions to conformational and colloidal stability.
Academic Article	Buffer-dependent fragmentation of a humanized full-length monoclonal antibody.
Academic Article	Subvisible particle counting provides a sensitive method of detecting and quantifying aggregation of monoclonal antibody caused by freeze-thawing: insights into the roles of particles in the protein aggregation pathway.
Academic Article	Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies.
Academic Article	Ionic strength affects tertiary structure and aggregation propensity of a monoclonal antibody adsorbed to silicone oil-water interfaces.
Academic Article	IgG1 aggregation and particle formation induced by silicone-water interfaces on siliconized borosilicate glass beads: a model for siliconized primary containers.
Academic Article	Sedimentation velocity analytical ultracentrifugation and SEDFIT/c(s): limits of quantitation for a monoclonal antibody system.
Academic Article	Response of a concentrated monoclonal antibody formulation to high shear.
Academic Article	Monoclonal antibody interactions with micro- and nanoparticles: adsorption, aggregation, and accelerated stress studies.
Academic Article	Inhibition of agitation-induced aggregation of an IgG-antibody by hydroxypropyl-beta-cyclodextrin.
Academic Article	Influence of protein conformation and adjuvant aggregation on the effectiveness of aluminum hydroxide adjuvant in a model alkaline phosphatase vaccine.
Academic Article	Precipitation of a monoclonal antibody by soluble tungsten.
Academic Article	Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution.
Academic Article	Excipient effects on humanized monoclonal antibody interactions with silicone oil emulsions.
Concept	Immunoglobulin Variable Region
Concept	Immunoglobulin E
Concept	Immunoglobulins, Intravenous
Concept	Immunoglobulin Light Chains
Concept	Immunoglobulin Fc Fragments
Concept	Immunoglobulin G
Academic Article	Antibody responses in mice to particles formed from adsorption of a murine monoclonal antibody onto glass microparticles.
Academic Article	Freezing-induced perturbation of tertiary structure of a monoclonal antibody.
Academic Article	Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration.
Academic Article	Investigation of the immunogenicity of different types of aggregates of a murine monoclonal antibody in mice.
Academic Article	Do not drop: mechanical shock in vials causes cavitation, protein aggregation, and particle formation.
Academic Article	Dose levels in particulate-containing formulations impact anti-drug antibody responses to murine monoclonal antibody in mice.
Academic Article	Effect of the siliconization method on particle generation in a monoclonal antibody formulation in pre-filled syringes.
Academic Article	In Vivo Analysis of the Potency of Silicone Oil Microdroplets as Immunological Adjuvants in Protein Formulations.
Academic Article	Mouse Models for Assessing Protein Immunogenicity: Lessons and Challenges.
Academic Article	Formation of Stable Nanobubbles on Reconstituting Lyophilized Formulations Containing Trehalose.
Academic Article	Reduced Subvisible Particle Formation in Lyophilized Intravenous Immunoglobulin Formulations Containing Polysorbate 20.
Academic Article	Immunogenicity of Structurally Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models.
Academic Article	Protein Nanoparticles Promote Microparticle Formation in Intravenous Immunoglobulin Solutions During Freeze-Thawing and Agitation Stresses.
Grant	Effect of Container Surface Structure on Cavitation-Induced Protein Particulate Formation
Academic Article	Rapid Quantification of Protein Particles in High-Concentration Antibody Formulations.
Academic Article	DEHP Nanodroplets Leached From Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum.
Academic Article	Subvisible Particles in IVIg Formulations Activate Complement in Human Serum.
Academic Article	Aggregation and Particle Formation During Pumping of an Antibody Formulation Are Controlled by Electrostatic Interactions Between Pump Surfaces and Protein Molecules.
Academic Article	The Effect of Container Surface Passivation on Aggregation of Intravenous Immunoglobulin Induced by Mechanical Shock.
Academic Article	Machine learning and statistical analyses for extracting and characterizing "fingerprints" of antibody aggregation at container interfaces from flow microscopy images.
Academic Article	Hydrogel Coatings on Container Surfaces Reduce Protein Aggregation Caused by Mechanical Stress and Cavitation.

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Immunoglobulins