Item Type | Name |
Academic Article
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Longitudinal changes in lung function among asbestos-exposed workers.
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Academic Article
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High-resolution CT-derived measures of lung density are valid indexes of interstitial lung disease.
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Academic Article
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Clinical relevance of cellular mediators of inflammation in workers exposed to asbestos.
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Academic Article
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Outcome of subjects with idiopathic pulmonary fibrosis who fail corticosteroid therapy. Implications for further studies.
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Academic Article
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The relationship between alveolar macrophage TNF, IL-1, and PGE2 release, alveolitis, and disease severity in sarcoidosis.
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Academic Article
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Role of endotoxin in grain dust-induced lung inflammation in mice.
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Academic Article
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The mast cell and idiopathic pulmonary fibrosis.
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Academic Article
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Pentoxifylline does not alter the response to inhaled grain dust.
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Academic Article
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Quantification of idiopathic pulmonary fibrosis using computed tomography and histology.
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Academic Article
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Peak flow as a measure of airway dysfunction in swine confinement operators.
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Academic Article
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Bacterial DNA or oligonucleotides containing unmethylated CpG motifs can minimize lipopolysaccharide-induced inflammation in the lower respiratory tract through an IL-12-dependent pathway.
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Academic Article
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Determinants of progression in idiopathic pulmonary fibrosis.
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Academic Article
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Nasal lavage cellularity, grain dust, and airflow obstruction.
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Academic Article
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TNF-alpha and IL-1 beta are not essential to the inflammatory response in LPS-induced airway disease.
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Academic Article
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Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities.
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Academic Article
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Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis.
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Academic Article
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CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract.
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Academic Article
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Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group.
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Academic Article
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The role of innate immunity in acute allograft rejection after lung transplantation.
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Academic Article
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Subchronic endotoxin inhalation causes persistent airway disease.
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Academic Article
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Fibrinolysis in LPS-induced chronic airway disease.
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Academic Article
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Ozone-induced acute pulmonary injury in inbred mouse strains.
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Academic Article
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Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.
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Academic Article
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The influence of cigarette smoking on lung function in patients with idiopathic pulmonary fibrosis.
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Academic Article
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From quantitative trait locus to gene: a work in progress.
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Academic Article
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High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis.
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Academic Article
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Clinical and pathologic features of familial interstitial pneumonia.
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Academic Article
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Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide.
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Academic Article
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Protection from experimental asthma by an endogenous bronchodilator.
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Academic Article
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The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
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Academic Article
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TLR4 signaling attenuates ongoing allergic inflammation.
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Academic Article
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Genetic basis of murine responses to hyperoxia-induced lung injury.
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Academic Article
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Genetic regulation of rejection and survival following human lung transplantation by the innate immune receptor CD14.
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Academic Article
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A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice.
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Academic Article
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Ambient ozone primes pulmonary innate immunity in mice.
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Academic Article
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Genetic basis of murine antibacterial defense to streptococcal lung infection.
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Academic Article
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Fibroproliferation in LPS-induced airway remodeling and bleomycin-induced fibrosis share common patterns of gene expression.
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Academic Article
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Chronic LPS inhalation causes emphysema-like changes in mouse lung that are associated with apoptosis.
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Academic Article
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Plasminogen alleles influence susceptibility to invasive aspergillosis.
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Academic Article
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Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice.
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Academic Article
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Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility.
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Academic Article
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Host-environment interactions in exposure-related diffuse lung diseases.
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Academic Article
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Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease.
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Academic Article
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Epigenetics and environmental lung disease.
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Academic Article
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Novel regulators of the systemic response to lipopolysaccharide.
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Academic Article
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A common MUC5B promoter polymorphism and pulmonary fibrosis.
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Academic Article
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Epigenetic control of gene expression in the lung.
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Academic Article
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Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred.
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Academic Article
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The pulmonary fibrosis-associated MUC5B promoter polymorphism does not influence the development of interstitial pneumonia in systemic sclerosis.
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Academic Article
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The genetic and environmental causes of pulmonary fibrosis.
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Academic Article
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Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist.
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Academic Article
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Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury.
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Academic Article
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Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure.
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Academic Article
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High-resolution CT scan findings in familial interstitial pneumonia do not conform to those of idiopathic interstitial pneumonia.
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Academic Article
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Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin.
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Academic Article
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Beta-arrestin-2 regulates the development of allergic asthma.
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Academic Article
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The role of endotoxin in grain dust-induced lung disease.
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Academic Article
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Low-dose methotrexate may cause air trapping in patients with rheumatoid arthritis.
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Academic Article
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Determinants of longitudinal changes in spirometric function among swine confinement operators and farmers.
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Academic Article
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Genetic regulation of endotoxin-induced airway disease.
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Academic Article
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Pulmonary fibrosis: thinking outside of the lung.
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Academic Article
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The relationship between HLA-A, B, DQ, and DR antigens and asbestos-induced lung disease.
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Academic Article
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Relative release of interleukin-1 beta and interleukin-1 receptor antagonist by alveolar macrophages. A study in asbestos-induced lung disease, sarcoidosis, and idiopathic pulmonary fibrosis.
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Academic Article
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The acute respiratory distress syndrome.
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Academic Article
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Innate immunity influences long-term outcomes after human lung transplant.
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Academic Article
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Endotoxin and the lung: Insight into the host-environment interaction.
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Academic Article
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Grain dust-induced lung inflammation is reduced by Rhodobacter sphaeroides diphosphoryl lipid A.
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Academic Article
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IL-10 reduces grain dust-induced airway inflammation and airway hyperreactivity.
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Academic Article
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Endotoxin responsiveness and subchronic grain dust-induced airway disease.
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Academic Article
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Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists.
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Academic Article
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Gene expression profiling of familial and sporadic interstitial pneumonia.
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Academic Article
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Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
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Academic Article
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Allergen-induced airway disease is mouse strain dependent.
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Academic Article
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The genetics of innate immunity in the lung.
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Academic Article
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CD14 is an essential mediator of LPS-induced airway disease.
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Academic Article
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CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
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Academic Article
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Finding fibrosis genes: the lung.
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Academic Article
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Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide.
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Academic Article
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Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin.
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Academic Article
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Complement levels and activity in the normal and LPS-injured lung.
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Academic Article
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Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury.
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Academic Article
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Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant.
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Academic Article
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Genomics and proteomics of lung disease: conference summary.
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Academic Article
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Association of the TLR4 Asp299Gly polymorphism with lung function in relation to body mass index.
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Academic Article
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Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury.
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Academic Article
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Nitric oxide mediates relative airway hyporesponsiveness to lipopolysaccharide in surfactant protein A-deficient mice.
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Academic Article
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The pulmonary sequelae associated with accidental inhalation of chlorine gas.
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Academic Article
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The lung: the natural boundary between nature and nurture.
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Academic Article
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Determinants of restrictive lung function in asbestos-induced pleural fibrosis.
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Academic Article
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Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report.
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Academic Article
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Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice.
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Academic Article
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The role of the E2F1 transcription factor in the innate immune response to systemic LPS.
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Academic Article
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The next generation of complex lung genetic studies.
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Academic Article
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Polymorphisms in the SUFU gene are associated with organ injury protection and sepsis severity in patients with Enterobacteriacea bacteremia.
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Academic Article
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Genetic predisposition to sarcoidosis: another brick in the wall.
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Academic Article
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Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.
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Academic Article
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Respiratory illness in the construction industry. Airflow obstruction among painters.
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Academic Article
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Genomic medicine and lung diseases.
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Academic Article
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Association of Toll-like receptor 2 gene polymorphisms with lung function in workers in swine operations.
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Academic Article
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MUC5B promoter polymorphism and interstitial lung abnormalities.
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Concept
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Ventilator-Induced Lung Injury
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Concept
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Lung Diseases, Obstructive
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Concept
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Lung Transplantation
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Concept
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Lung Neoplasms
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Concept
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Lung Diseases, Fungal
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Concept
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Lung Injury
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Concept
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Acute Lung Injury
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Concept
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Lung Volume Measurements
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Concept
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National Heart, Lung, and Blood Institute (U.S.)
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Concept
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Lung Diseases
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Concept
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Total Lung Capacity
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Concept
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Lung Diseases, Interstitial
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Concept
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Lung
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Concept
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Lung Compliance
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Academic Article
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The MUC5B variant is associated with idiopathic pulmonary fibrosis but not with systemic sclerosis interstitial lung disease in the European Caucasian population.
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Academic Article
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Muc5b is required for airway defence.
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Academic Article
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Diffuse lung disease in children: summary of a scientific conference.
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Academic Article
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NOS3 polymorphism, lung function, and exposure in swine operations: results of 2 studies.
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Academic Article
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Integrative genetic analysis of allergic inflammation in the murine lung.
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Academic Article
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CT scan findings of probable usual interstitial pneumonitis have a high predictive value for histologic usual interstitial pneumonitis.
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Academic Article
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Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data.
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Academic Article
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The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
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Academic Article
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Rare variants in RTEL1 are associated with familial interstitial pneumonia.
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Academic Article
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Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias.
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Academic Article
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A comparison of visual and quantitative methods to identify interstitial lung abnormalities.
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Academic Article
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MUC5B and Idiopathic Pulmonary Fibrosis.
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Academic Article
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In Utero Cigarette Smoke Affects Allergic Airway Disease But Does Not Alter the Lung Methylome.
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Academic Article
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MUC5B expression and location in surfactant protein C mutations in children.
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Academic Article
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CT Imaging Phenotypes of Pulmonary Fibrosis in the MUC5B Promoter Site Polymorphism.
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Academic Article
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Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study.
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Academic Article
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Pulmonary fibrosis in the era of stratified medicine.
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Academic Article
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Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
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Academic Article
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Plasma Soluble Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis.
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Academic Article
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Regulation of MUC5B Expression in Idiopathic Pulmonary Fibrosis.
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Grant
|
ASBESTOS-INDUCED PLEURAL FIBROSIS &LUNG RESTRICTION
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Grant
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The Pathogenesis and Genetics of Environmental Asthma
|
Grant
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GRAIN DUST, ENDOTOXIN, AND AIRFLOW OBSTRUCTION
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Grant
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FASEB SRC on The Lung Epithelium in Health and Disease
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Grant
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Functional Genetics in Idiopathic Pulmonary Fibrosis
|
Grant
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Lung Genomics Research Consortium
|
Grant
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Functional Genetics in Idiopathic Pulmonary Fibrosis
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Grant
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Genetic and Epigenetic Changes in MUC5B and Fibrosing Interstitial Lung Disease
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Grant
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Environmental Determinants of Airway Disease in Children
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Grant
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MICROARRAY EXPRESSION PROFILING OF RODENT MODELS OF HUMA
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Grant
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MUC5B, a novel therapeutic target for Idiopathic Pulmonary Fibrosis (IPF)
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Grant
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Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia
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Grant
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Asthma: An Epidemic Caused by Epigenetics?
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Academic Article
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Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis.
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Academic Article
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The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes.
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Grant
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MUC5B, a novel therapeutic target for Idiopathic Pulmonary Fibrosis (IPF)
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Academic Article
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Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?
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Academic Article
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The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.
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Academic Article
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Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.
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Academic Article
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Introduction to the 60th Annual Thomas L. Petty Aspen Lung Conference. Environment and Global Lung Health: Exposure, Susceptibility, and Intervention.
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Academic Article
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MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease.
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Academic Article
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Gender-specific associations between polymorphisms in the Toll-like receptor (TLR) genes and lung function among workers in swine operations.
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Academic Article
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Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.
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Academic Article
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Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.
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Academic Article
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Imaging Patterns Are Associated with Interstitial Lung Abnormality Progression and Mortality.
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Academic Article
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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
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Academic Article
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Is Progression of Pulmonary Fibrosis due to Ventilation-induced Lung Injury?
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Academic Article
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Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.
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Academic Article
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Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study.
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Academic Article
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Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures.
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Academic Article
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Methotrexate and rheumatoid arthritis associated interstitial lung disease.
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Grant
|
Preclinical Pulmonary Fibrosis, an opportune rare disease cohort
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Academic Article
|
Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
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Academic Article
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The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling.
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Academic Article
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Molecular markers of telomere dysfunction and senescence are common findings in the usual interstitial pneumonia pattern of lung fibrosis.
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Academic Article
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
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Academic Article
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Effects of tumor necrosis factor (TNF) gene polymorphisms on the association between smoking and lung function among workers in swine operations.
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Academic Article
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Molecular Signatures of Idiopathic Pulmonary Fibrosis.
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Academic Article
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Genes, other than Muc5b, play a role in bleomycin-induced lung fibrosis.
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Academic Article
|
Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional.
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Academic Article
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MUC5B promoter variant rs35705950 and rheumatoid arthritis associated interstitial lung disease survival and progression.
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Academic Article
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Prospective Identification of Subclinical Interstitial Lung Disease in a Rheumatoid Arthritis Cohort Is Associated with the MUC5B Promoter Variant.
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Academic Article
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Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis.
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Academic Article
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Integrin Axis Regulates Airway Biophysical Dysfunction in Idiopathic Pulmonary Fibrosis.
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Academic Article
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Interleukin-6-dependent epithelial fluidization initiates fibrotic lung remodeling.
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Academic Article
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Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced by Saccharopolyspora rectivirgula.
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Academic Article
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Epithelial Endoplasmic Reticulum Stress Enhances the Risk of Muc5b-associated Lung Fibrosis.
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Academic Article
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The Genetic Landscape of Familial Pulmonary Fibrosis.
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Academic Article
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Preclinical interstitial lung disease in relatives of familial pulmonary fibrosis patients.
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Academic Article
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Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort.
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Academic Article
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Long-term exposure to house dust mites accelerates lung cancer development in mice.
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Academic Article
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Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis.
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Academic Article
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Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis.
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Academic Article
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A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.
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Academic Article
|
Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis.
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Academic Article
|
Pulmonary Fibrosis Stakeholder Summit: A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report.
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Grant
|
Mechanisms Regulating Lung Injury and Early Lung Fibrosis
|
Grant
|
Aspen Lung Conference Pulmonary Fibrosis - focusing on the future
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