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Search Results to David A Schwartz

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Schwartz, David

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Item Type	Name
Academic Article	Endotoxin responsiveness and grain dust-induced inflammation in the lower respiratory tract.
Academic Article	High-resolution CT-derived measures of lung density are valid indexes of interstitial lung disease.
Academic Article	Asbestos-induced pleural fibrosis and impaired exercise physiology.
Academic Article	The relationship between alveolar macrophage TNF, IL-1, and PGE2 release, alveolitis, and disease severity in sarcoidosis.
Academic Article	The kinetics of grain dust-induced inflammation of the lower respiratory tract.
Academic Article	Peak flow as a measure of airway dysfunction in swine confinement operators.
Academic Article	Etiology and pathogenesis of airway disease in children and adults from rural communities.
Academic Article	Nasal lavage cellularity, grain dust, and airflow obstruction.
Academic Article	TNF-alpha and IL-1 beta are not essential to the inflammatory response in LPS-induced airway disease.
Academic Article	Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities.
Academic Article	The role of TLR4 in endotoxin responsiveness in humans.
Academic Article	American Thoracic Society Statement: Occupational contribution to the burden of airway disease.
Academic Article	Intercellular adhesion molecule-1 plays a pivotal role in endotoxin-induced airway disease.
Academic Article	The role of innate immunity in acute allograft rejection after lung transplantation.
Academic Article	Subchronic endotoxin inhalation causes persistent airway disease.
Academic Article	Fibrinolysis in LPS-induced chronic airway disease.
Academic Article	Ozone-induced acute pulmonary injury in inbred mouse strains.
Academic Article	Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.
Academic Article	The role of Toll-like receptor 4 in environmental airway injury in mice.
Academic Article	Mica-associated pulmonary interstitial fibrosis.
Academic Article	A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis.
Academic Article	Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression.
Academic Article	From quantitative trait locus to gene: a work in progress.
Academic Article	New developments in asbestos-induced pleural disease.
Academic Article	Toll-like receptors in the pathogenesis of human disease.
Academic Article	Clinical and pathologic features of familial interstitial pneumonia.
Academic Article	Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness.
Academic Article	Genetic basis of murine responses to hyperoxia-induced lung injury.
Academic Article	The IL-1 type 1 receptor is required for the development of LPS-induced airways disease.
Academic Article	A micro-computed tomography-based method for the measurement of pulmonary compliance in healthy and bleomycin-exposed mice.
Academic Article	Genetic basis of murine antibacterial defense to streptococcal lung infection.
Academic Article	Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice.
Academic Article	Plasminogen alleles influence susceptibility to invasive aspergillosis.
Academic Article	In utero supplementation with methyl donors enhances allergic airway disease in mice.
Academic Article	Gene-environment interactions and airway disease in children.
Academic Article	Host-environment interactions in exposure-related diffuse lung diseases.
Academic Article	Molecular phenotypes distinguish patients with relatively stable from progressive idiopathic pulmonary fibrosis (IPF).
Academic Article	Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease.
Academic Article	Ecogenomics of respiratory diseases of public health significance.
Academic Article	Monocyte-derived growth factors in asbestos-induced interstitial fibrosis.
Academic Article	Epigenetics and environmental lung disease.
Academic Article	Environmental genomics and human health.
Academic Article	A common MUC5B promoter polymorphism and pulmonary fibrosis.
Academic Article	Epigenetic control of gene expression in the lung.
Academic Article	A locus on chromosome 9 is associated with differential response of 129S1/SvImJ and FVB/NJ strains of mice to systemic LPS.
Academic Article	Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred.
Academic Article	Toll-like receptor 4 polymorphisms and atherogenesis.
Academic Article	The pulmonary fibrosis-associated MUC5B promoter polymorphism does not influence the development of interstitial pneumonia in systemic sclerosis.
Academic Article	The peripheral blood transcriptome identifies the presence and extent of disease in idiopathic pulmonary fibrosis.
Academic Article	The genetic and environmental causes of pulmonary fibrosis.
Academic Article	Molecular mechanisms in progressive idiopathic pulmonary fibrosis.
Academic Article	Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury.
Academic Article	High-resolution CT scan findings in familial interstitial pneumonia do not conform to those of idiopathic interstitial pneumonia.
Academic Article	Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin.
Academic Article	The role of endotoxin in grain dust-induced lung disease.
Academic Article	Determinants of longitudinal changes in spirometric function among swine confinement operators and farmers.
Academic Article	Genetic regulation of endotoxin-induced airway disease.
Academic Article	Pulmonary fibrosis: thinking outside of the lung.
Academic Article	Grain dust-induced airflow obstruction and inflammation of the lower respiratory tract.
Academic Article	The relationship between HLA-A, B, DQ, and DR antigens and asbestos-induced lung disease.
Academic Article	Relative release of interleukin-1 beta and interleukin-1 receptor antagonist by alveolar macrophages. A study in asbestos-induced lung disease, sarcoidosis, and idiopathic pulmonary fibrosis.
Academic Article	Grain dust and endotoxin inhalation challenges produce similar inflammatory responses in normal subjects.
Academic Article	The role of atopy in grain dust-induced airway disease.
Academic Article	Endotoxin and the lung: Insight into the host-environment interaction.
Academic Article	The effect of of glucocorticoids on grain dust-induced airway disease.
Academic Article	Polymorphisms of the Toll-like receptors and human disease.
Academic Article	IL-10 reduces grain dust-induced airway inflammation and airway hyperreactivity.
Academic Article	Endotoxin responsiveness and subchronic grain dust-induced airway disease.
Academic Article	Future of toxicology--a shift in the paradigm: focus on human disease.
Academic Article	Gene expression profiling of familial and sporadic interstitial pneumonia.
Academic Article	The importance of gene-environment interactions and exposure assessment in understanding human diseases.
Academic Article	Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
Academic Article	TLR4 and LPS hyporesponsiveness in humans.
Academic Article	Allergen-induced airway disease is mouse strain dependent.
Academic Article	The genetics of innate immunity in the lung.
Academic Article	Environmental genomics: a key to understanding biology, pathophysiology and disease.
Academic Article	Analyses of efficacy end points in a controlled trial of interferon-gamma1b for idiopathic pulmonary fibrosis.
Academic Article	CD14 is an essential mediator of LPS-induced airway disease.
Academic Article	CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
Academic Article	Finding fibrosis genes: the lung.
Academic Article	The effect of toll-like receptors and toll-like receptor genetics in human disease.
Academic Article	3He MRI in mouse models of asthma.
Academic Article	Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide.
Academic Article	Serum inter-alpha-trypsin inhibitor and matrix hyaluronan promote angiogenesis in fibrotic lung injury.
Academic Article	Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant.
Academic Article	Using mouse genomics to understand idiopathic interstitial fibrosis.
Academic Article	Genomics and proteomics of lung disease: conference summary.
Academic Article	Inter-alpha-trypsin inhibitor attenuates complement activation and complement-induced lung injury.
Academic Article	Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts.
Academic Article	The pulmonary sequelae associated with accidental inhalation of chlorine gas.
Academic Article	The lung: the natural boundary between nature and nurture.
Academic Article	Translating the genome.
Academic Article	Determinants of restrictive lung function in asbestos-induced pleural fibrosis.
Academic Article	Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report.
Academic Article	Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice.
Academic Article	Chagasic cardiomyopathy, from acute to chronic: is this mediated by host susceptibility factors?
Academic Article	The next generation of complex lung genetic studies.
Academic Article	Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients.
Academic Article	Genetic predisposition to sarcoidosis: another brick in the wall.
Academic Article	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.
Academic Article	Respiratory illness in the construction industry. Airflow obstruction among painters.
Academic Article	Genomic medicine and lung diseases.
Academic Article	MUC5B promoter polymorphism and interstitial lung abnormalities.
Concept	Autoimmune Diseases
Concept	Lung Diseases, Obstructive
Concept	Disease Models, Animal
Concept	Pulmonary Disease, Chronic Obstructive
Concept	Communicable Diseases
Concept	Lung Diseases, Fungal
Concept	Skin Diseases
Concept	Esophageal Diseases
Concept	Disease Progression
Concept	Occupational Diseases
Concept	Infectious Disease Transmission, Vertical
Concept	Placenta Diseases
Concept	Disease Susceptibility
Concept	Chronic Disease
Concept	Respiratory Tract Diseases
Concept	Disease-Free Survival
Concept	Agricultural Workers' Diseases
Concept	Acute Disease
Concept	Crohn Disease
Concept	Inflammatory Bowel Diseases
Concept	Immune Complex Diseases
Concept	Disease Outbreaks
Concept	Genetic Predisposition to Disease
Concept	Pleural Diseases
Concept	Cardiovascular Diseases
Concept	Lung Diseases
Concept	Carotid Artery Diseases
Concept	Gastrointestinal Diseases
Concept	Lung Diseases, Interstitial
Concept	Disease
Academic Article	The MUC5B variant is associated with idiopathic pulmonary fibrosis but not with systemic sclerosis interstitial lung disease in the European Caucasian population.
Academic Article	Muc5b is required for airway defence.
Academic Article	Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
Academic Article	Inhibition of peroxisome proliferator-activated receptor ?: a potential link between chronic maternal hypoxia and impaired fetal growth.
Academic Article	Diffuse lung disease in children: summary of a scientific conference.
Academic Article	Genetic susceptibility and pulmonary fibrosis.
Academic Article	A mouse model links asthma susceptibility to prenatal exposure to diesel exhaust.
Academic Article	Integrative genetic analysis of allergic inflammation in the murine lung.
Academic Article	The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis.
Academic Article	Epigenetics of idiopathic pulmonary fibrosis.
Academic Article	CT scan findings of probable usual interstitial pneumonitis have a high predictive value for histologic usual interstitial pneumonitis.
Academic Article	Rare variants in RTEL1 are associated with familial interstitial pneumonia.
Academic Article	A comparison of visual and quantitative methods to identify interstitial lung abnormalities.
Academic Article	MUC5B and Idiopathic Pulmonary Fibrosis.
Academic Article	In Utero Cigarette Smoke Affects Allergic Airway Disease But Does Not Alter the Lung Methylome.
Academic Article	TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis.
Academic Article	Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia.
Academic Article	Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways.
Academic Article	Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.
Academic Article	Development and Progression of Interstitial Lung Abnormalities in the Framingham Heart Study.
Academic Article	Pulmonary fibrosis in the era of stratified medicine.
Academic Article	Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
Academic Article	Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Academic Article	Plasma Soluble Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis.
Grant	Multi-Disciplinary Research Training in Respiratory Disease
Grant	Antenatal Dietary Supplementation is a Risk Factor for Infant Atopy Through Epige
Grant	The Pathogenesis and Genetics of Environmental Asthma
Grant	GRAIN DUST, ENDOTOXIN, AND AIRFLOW OBSTRUCTION
Grant	FASEB SRC on The Lung Epithelium in Health and Disease
Grant	Functional Genetics in Idiopathic Pulmonary Fibrosis
Grant	Center for Comparative Biology of Vulnerable Populations
Grant	EPIDEMIOLOGY OF VEGETABLE DUST-INDUCED AIRWAY DISEASE
Grant	Lung Genomics Research Consortium
Grant	Functional Genetics in Idiopathic Pulmonary Fibrosis
Grant	HOST DETERMINANTS OF ORGANIC DUST INDUCED AIRWAY DISEASE
Grant	Genetic and Epigenetic Changes in MUC5B and Fibrosing Interstitial Lung Disease
Grant	Supercomputer Linux Cluster for Genomics and Proteomics
Grant	AIRWAY DISEASE IN CHILDREN FROM RURAL COMMUNITIES
Grant	Environmental Determinants of Airway Disease in Children
Grant	Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
Grant	MICROARRAY EXPRESSION PROFILING OF RODENT MODELS OF HUMA
Grant	A LINKAGE STUDY IN FAMILIAL PULMONARY FIBROSIS
Grant	MUC5B, a novel therapeutic target for Idiopathic Pulmonary Fibrosis (IPF)
Grant	CENTER FOR ENVIRONMENTAL GENOMICS
Grant	Peripheral Blood Biomarkers for Idiopathic Interstitial Pneumonia
Grant	Genomic Signatures for Idiopathic Interstitial Pneumonia
Grant	Asthma: An Epidemic Caused by Epigenetics?
Academic Article	Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis.
Academic Article	Comparison of Health Care Utilization and Costs Between Patients with Perianal Fistulizing Crohn's Disease Treated with Biologics with or Without Previous Seton Placement.
Academic Article	A guiding map for inflammation.
Academic Article	The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes.
Grant	MUC5B, a novel therapeutic target for Idiopathic Pulmonary Fibrosis (IPF)
Academic Article	Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.
Academic Article	Methylene-tetrahydrofolate reductase contributes to allergic airway disease.
Academic Article	Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.
Academic Article	Age Modifies the Association Between Depressive Symptoms and Adherence to Self-Testing With Telemedicine in Patients With Inflammatory Bowel Disease.
Academic Article	MUC5B Promoter Polymorphism and Development of Acute Respiratory Distress Syndrome.
Academic Article	Deciphering the Genetics of Chronic Obstructive Pulmonary Disease.
Academic Article	MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease.
Academic Article	Idiopathic Pulmonary Fibrosis Is a Genetic Disease Involving Mucus and the Peripheral Airways.
Academic Article	Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.
Academic Article	Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.
Academic Article	Imaging Patterns Are Associated with Interstitial Lung Abnormality Progression and Mortality.
Academic Article	Translational research in pulmonary fibrosis.
Academic Article	Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
Academic Article	Serum Polyunsaturated Fatty Acids Correlate with Serum Cytokines and Clinical Disease Activity in Crohn's Disease.
Academic Article	Is Progression of Pulmonary Fibrosis due to Ventilation-induced Lung Injury?
Academic Article	A2ML1 and otitis media: novel variants, differential expression, and relevant pathways.
Academic Article	Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis.
Academic Article	Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.
Academic Article	The Expanding Role of Anti-IL-12 and/or Anti-IL-23 Antibodies in the Treatment of Inflammatory Bowel Disease.
Academic Article	MUC5B variant is associated with visually and quantitatively detected preclinical pulmonary fibrosis.
Academic Article	Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.
Academic Article	Identification of Novel Genes and Biological Pathways That Overlap in Infectious and Nonallergic Diseases of the Upper and Lower Airways Using Network Analyses.
Academic Article	Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections.
Academic Article	Practical guidelines on endoscopic treatment for Crohn's disease strictures: a consensus statement from the Global Interventional Inflammatory Bowel Disease Group.
Academic Article	An Analysis of 38 Pregnant Women With COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes.
Academic Article	Precision nicotine metabolism-informed care for smoking cessation in Crohn's disease: A pilot study.
Academic Article	Gastric contents in children presenting for upper endoscopy.
Academic Article	Patterns of endoscopy during COVID-19 pandemic: a global survey of interventional inflammatory bowel disease practice.
Academic Article	Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures.
Academic Article	Methotrexate and rheumatoid arthritis associated interstitial lung disease.
Academic Article	Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 From the Mother to the Infant.
Academic Article	Gastroenterologist-Lead Management of Iron Deficiency Anemia in Inflammatory Bowel Disease Is Effective, Safe, and May Increase Quality of Life.
Grant	Preclinical Pulmonary Fibrosis, an opportune rare disease cohort
Academic Article	Characterizing COVID-19 maternal-fetal transmission and placental infection using comprehensive molecular pathology.
Academic Article	Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
Academic Article	The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling.
Academic Article	Chronic Histiocytic Intervillositis With Trophoblast Necrosis Is a Risk Factor Associated With Placental Infection From Coronavirus Disease 2019 (COVID-19) and Intrauterine Maternal-Fetal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission in Live-Born and Stillborn Infants.
Academic Article	Endoscopic evaluation of surgically altered bowel in inflammatory bowel disease: a consensus guideline from the Global Interventional Inflammatory Bowel Disease Group.
Academic Article	Coronavirus Diseases in Pregnant Women, the Placenta, Fetus, and Neonate.
Academic Article	Safety and Efficacy of Vedolizumab Versus Tumor Necrosis Factor a Antagonists in an Elderly IBD Population: A Single Institution Retrospective Experience.
Academic Article	Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional.
Academic Article	Endoscopic evaluation after surgery in inflammatory bowel disease - Authors' reply.
Academic Article	Diagnosis and classification of ileal pouch disorders: consensus guidelines from the International Ileal Pouch Consortium.
Academic Article	Efficacy and Safety of 2 Vedolizumab Intravenous Regimens for Perianal Fistulizing Crohn's Disease: ENTERPRISE Study.
Academic Article	MUC5B promoter variant rs35705950 and rheumatoid arthritis associated interstitial lung disease survival and progression.
Academic Article	Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infecting Pregnant Women and the Fetus, Intrauterine Transmission, and Placental Pathology During the Coronavirus Disease 2019 (COVID-19) Pandemic: It's Complicated.
Academic Article	Treatment of pouchitis, Crohn's disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium.
Academic Article	Prospective Identification of Subclinical Interstitial Lung Disease in a Rheumatoid Arthritis Cohort Is Associated with the MUC5B Promoter Variant.
Academic Article	Placental Tissue Destruction and Insufficiency From COVID-19 Causes Stillbirth and Neonatal Death From Hypoxic-Ischemic Injury.
Academic Article	Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis.
Academic Article	Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis.
Academic Article	Muc5b plays a role in the development of inflammation and fibrosis in hypersensitivity pneumonitis induced by Saccharopolyspora rectivirgula.
Academic Article	Genetic diversity fuels gene discovery for tobacco and alcohol use.
Academic Article	The Genetic Landscape of Familial Pulmonary Fibrosis.
Academic Article	Preclinical interstitial lung disease in relatives of familial pulmonary fibrosis patients.
Academic Article	Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing.
Academic Article	Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort.
Academic Article	Long-term exposure to house dust mites accelerates lung cancer development in mice.
Academic Article	Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis.
Academic Article	A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.

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