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Search Results to Nanette F Santoro

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Santoro, Nanette

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My research focuses on the pathophysiology of several reproductive conditions. The first of these is premature, natural and medically/surgically induced menopause in women and its treatment. I have been an investigator and past PI of the New Jersey site for the Study of Women's Health Across the Nation (SWAN) a multi center cohort study of the menopausal transition and beyond. I have been a co-investigator for the Women's Health Initiative Clinical Trial at both New Jersey and Albert Einstein, and am a past site PI for the Kronos Early Estrogen Prevention Study (KEEPS). I am past chair of the Steering Committee for the Reproductive Medicine Network (RMN) and member of CONFIRM Consortium for clinical trials in Reproductive Medicine. Both are multi center NIH funded clinical trials networks that perform cutting edge clinical studies in the field of reproduction and have published a number of high-impact, practice-changing manuscripts in recent years. Last but not least, my laboratory is currently focused on the reproductive hormonal dysfunction that occurs in obesity and how it might be related to suboptimal fertility and pregnancy outcomes.

One or more keywords matched the following items that are connected to Santoro, Nanette

Item Type	Name
Academic Article	The physiology of gonadotropin-releasing hormone (GnRH) secretion in men and women.
Academic Article	Benefits of continuous physiological pulsatile gonadotropin-releasing hormone therapy in women with polycystic ovarian syndrome.
Academic Article	Effects of aging and gonadal failure on the hypothalamic-pituitary axis in women.
Academic Article	Diminished function of the somatotropic axis in older reproductive-aged women.
Academic Article	Luteal progesterone relates to histological endometrial maturation in fertile women.
Academic Article	Body size and ethnicity are associated with menstrual cycle alterations in women in the early menopausal transition: The Study of Women's Health across the Nation (SWAN) Daily Hormone Study.
Academic Article	Decreased inhibin tone and increased activin A secretion characterize reproductive aging in women.
Academic Article	Correlates of circulating androgens in mid-life women: the study of women's health across the nation.
Academic Article	Relation of cardiovascular risk factors in women approaching menopause to menstrual cycle characteristics and reproductive hormones in the follicular and luteal phases.
Academic Article	Impact of street drug use, HIV infection, and highly active antiretroviral therapy on reproductive hormones in middle-aged women.
Academic Article	Androgen therapy in women: an Endocrine Society Clinical Practice guideline.
Academic Article	Factors affecting reproductive hormones in HIV-infected, substance-using middle-aged women.
Academic Article	Duration of lactation is associated with lower prevalence of the metabolic syndrome in midlife--SWAN, the study of women's health across the nation.
Academic Article	Attribution of menopause symptoms in human immunodeficiency virus-infected or at-risk drug-using women.
Academic Article	The relationship of bleeding patterns to daily reproductive hormones in women approaching menopause.
Academic Article	Partial recovery of luteal function after bariatric surgery in obese women.
Academic Article	Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women: study of Women's Health Across the Nation.
Academic Article	Prevalence and impact of vaginal symptoms among postmenopausal women.
Academic Article	Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS).
Academic Article	Metformin does not improve the reproductive or metabolic profile in women with polycystic ovary syndrome (PCOS).
Academic Article	The relationship between psychosocial status, acculturation and country of origin in mid-life Hispanic women: data from the Study of Women's Health Across the Nation (SWAN).
Academic Article	Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the Nation.
Academic Article	Differences in urinary excretion patterns of the hLH beta core fragment in premenopausal, perimenopausal, and postmenopausal women.
Academic Article	Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome.
Academic Article	Ethical considerations in the treatment of infertility in women with human immunodeficiency virus infection.
Academic Article	Assessing comprehension of clinical research.
Academic Article	Enhanced hypothalamic-pituitary sensitivity to estrogen in premenopausal women with diminished ovarian reserve compared with older perimenopausal controls.
Academic Article	Increased incident hip fractures in postmenopausal women with moderate to severe pelvic organ prolapse.
Academic Article	Relative contributions of oligomenorrhea and hyperandrogenemia to the risk of metabolic syndrome in midlife women.
Academic Article	Endometrial shedding effect on conception and live birth in women with polycystic ovary syndrome.
Academic Article	Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women.
Academic Article	Gonadotropin-releasing hormone (GnRH) physiology in men and women.
Academic Article	Ethnic differences in insulin sensitivity and beta-cell function in premenopausal or early perimenopausal women without diabetes: the Study of Women's Health Across the Nation (SWAN).
Academic Article	Suppression of the hypothalamic-pituitary-ovarian axis in normal women by glucocorticoids.
Academic Article	Evidence for diminished midcycle ovarian androgen production in older reproductive aged women.
Academic Article	Disorders of glucose metabolism among HIV-infected women.
Academic Article	Relationship of day-to-day reproductive hormone levels to sleep in midlife women.
Academic Article	HIV infection and bone mineral density in middle-aged women.
Academic Article	Gonadotropin and inhibin concentrations in early pregnancy in women with and without corpora lutea.
Academic Article	Postmenopausal hormone therapy: new questions and the case for new clinical trials.
Academic Article	Comparison of SWAN and WISE menopausal status classification algorithms.
Academic Article	Lowering low density lipoprotein cholesterol with simvastatin, a hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, does not affect luteal function in premenopausal women.
Academic Article	Risk factor clustering in the insulin resistance syndrome and its relationship to cardiovascular disease in postmenopausal white, black, hispanic, and Asian/Pacific Islander women.
Academic Article	Impaired folliculogenesis and ovulation in older reproductive aged women.
Academic Article	Lessons learned from the WHI: HRT requires a cautious and individualized approach.
Academic Article	Assessment of the proliferative status of epithelial cell types in the endometrium of young and menopausal transition women.
Academic Article	Menopause symptoms in HIV-infected and drug-using women.
Academic Article	Vasomotor symptoms in infertile premenopausal women: a hitherto unappreciated risk for low bone mineral density.
Academic Article	Association of pelvic organ prolapse and fractures in postmenopausal women: analysis of baseline data from the Women's Health Initiative Estrogen Plus Progestin trial.
Academic Article	Factors related to declining luteal function in women during the menopausal transition.
Academic Article	Increased serum lipids are associated with higher CD4 lymphocyte count in HIV-infected women.
Academic Article	Low serum osteoprotegerin levels in premenopausal infertile women with low bone density: an association of relevance?
Academic Article	Body shape and size and insulin resistance as early clinical predictors of hyperandrogenic anovulation in ethnic minority adolescent girls.
Academic Article	Helping midlife women predict the onset of the final menses: SWAN, the Study of Women's Health Across the Nation.
Academic Article	Pulsatile luteinizing hormone amplitude and progesterone metabolite excretion are reduced in obese women.
Academic Article	Women and HIV infection: the makings of a midlife crisis.
Academic Article	Onset of ovulation after menarche in girls: a longitudinal study.
Academic Article	Longitudinal changes in hypothalamic and ovarian function in perimenopausal women with anovulatory cycles: relationship with vasomotor symptoms.
Academic Article	Chronic psychosocial stressors are detrimental to ovarian reserve: a study of infertile women.
Academic Article	Attitudes toward menopause in HIV-infected and at-risk women.
Academic Article	Characterizing the reproductive hormone milieu in infertile women with diminished ovarian reserve.
Academic Article	Association of adolescent obesity and lifetime nulliparity--the Study of Women's Health Across the Nation (SWAN).
Academic Article	Menopausal symptoms and ethnicity: the Study of Women's Health Across the Nation.
Academic Article	Cardiovascular risk factor variation within a Hispanic cohort: SWAN, the Study of Women's Health Across the Nation.
Academic Article	Aromatase inhibition causes increased amplitude, but not frequency, of hypothalamic-pituitary output in normal women.
Academic Article	Menopausal symptoms within a Hispanic cohort: SWAN, the Study of Women's Health Across the Nation.
Academic Article	Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism.
Academic Article	Skin wrinkles and rigidity in early postmenopausal women vary by race/ethnicity: baseline characteristics of the skin ancillary study of the KEEPS trial.
Academic Article	Circulating dehydroepiandrosterone sulfate levels in women who underwent bilateral salpingo-oophorectomy during the menopausal transition.
Academic Article	Adiposity and hot flashes in midlife women: a modifying role of age.
Academic Article	Differential granulosa cell gene expression in young women with diminished ovarian reserve.
Academic Article	Association of ethnicity with involuntary childlessness and perceived reasons for infertility: baseline data from the Study of Women's Health Across the Nation (SWAN).
Academic Article	The SWAN song: Study of Women's Health Across the Nation's recurring themes.
Academic Article	Impaired gremlin 1 (GREM1) expression in cumulus cells in young women with diminished ovarian reserve (DOR).
Academic Article	Are vasomotor symptoms associated with sleep characteristics among symptomatic midlife women? Comparisons of self-report and objective measures.
Academic Article	Do changes in sex steroid hormones precede or follow increases in body weight during the menopause transition? Results from the Study of Women's Health Across the Nation.
Academic Article	Prospective evaluation of bone mineral density among middle-aged HIV-infected and uninfected women: Association between methadone use and bone loss.
Academic Article	Intra-thoracic fat, cardiometabolic risk factors, and subclinical cardiovascular disease in healthy, recently menopausal women screened for the Kronos Early Estrogen Prevention Study (KEEPS).
Academic Article	Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovarian disease: indirect evidence for partial gonadotroph desensitization.
Academic Article	Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone.
Concept	Women's Health
Concept	Pregnant Women
Concept	Women
Academic Article	Ectopic fat and adipokines in metabolically benign overweight/obese women: the Kronos Early Estrogen Prevention Study.
Academic Article	Menopausal hormone therapy and menopausal symptoms.
Academic Article	Evidence of GnRH antagonist escape in obese women.
Academic Article	Profound reduction of ovarian estrogen by aromatase inhibition in obese women.
Academic Article	Progression from metabolically benign to at-risk obesity in perimenopausal women: a longitudinal analysis of study of women across the nation (SWAN).
Academic Article	Luteal phase dynamics of follicle-stimulating and luteinizing hormones in obese and normal weight women.
Academic Article	Associations between retinol-binding protein 4 and cardiometabolic risk factors and subclinical atherosclerosis in recently postmenopausal women: cross-sectional analyses from the KEEPS study.
Academic Article	Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial.
Academic Article	Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline.
Academic Article	Evidence for prolonged and unique amenorrhea-related symptoms in women with premature ovarian failure/primary ovarian insufficiency.
Academic Article	Consistent ovulation may not be enough to make women healthy when approaching menopause: an update from the Study of Women's Health Across the Nation.
Academic Article	Impact of Male and Female Weight, Smoking, and Intercourse Frequency on Live Birth in Women With Polycystic Ovary Syndrome.
Academic Article	Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study.
Academic Article	Identification and replication of prediction models for ovulation, pregnancy and live birth in infertile women with polycystic ovary syndrome.
Academic Article	Compounded bioidentical hormone therapy: identifying use trends and knowledge gaps among US women.
Academic Article	Estradiol Priming Improves Gonadotrope Sensitivity and Pro-Inflammatory Cytokines in Obese Women.
Academic Article	Chlamydia trachomatis immunoglobulin G3 seropositivity is a predictor of reproductive outcomes in infertile women with patent fallopian tubes.
Academic Article	Use of a levonorgestrel-containing intrauterine system with supplemental estrogen improves symptoms in perimenopausal women: a pilot study.
Academic Article	Role of Estrogens and Estrogen-Like Compounds in Female Sexual Function and Dysfunction.
Academic Article	Androgens and Female Sexual Function and Dysfunction--Findings From the Fourth International Consultation of Sexual Medicine.
Academic Article	Compounded Bioidentical Hormones in Endocrinology Practice: An Endocrine Society Scientific Statement.
Academic Article	Perimenopause: From Research to Practice.
Academic Article	Changes in heart rate variability during vasomotor symptoms among midlife women.
Academic Article	Sex hormones in women with and without migraine: Evidence of migraine-specific hormone profiles.
Academic Article	Vitamin D Status Relates to Reproductive Outcome in Women With Polycystic Ovary Syndrome: Secondary Analysis of a Multicenter Randomized Controlled Trial.
Academic Article	Baseline AMH Level Associated With Ovulation Following Ovulation Induction in Women With Polycystic Ovary Syndrome.
Academic Article	Child Abuse and Neglect and Subclinical Cardiovascular Disease Among Midlife Women.
Academic Article	Duration of the menopausal transition is longer in women with young age at onset: the multiethnic Study of Women's Health Across the Nation.
Academic Article	Menopausal Hot Flashes and Carotid Intima Media Thickness Among Midlife Women.
Academic Article	Longitudinal changes in menopausal symptoms comparing women randomized to low-dose oral conjugated estrogens or transdermal estradiol plus micronized progesterone versus placebo: the Kronos Early Estrogen Prevention Study.
Academic Article	Sleep Characteristics and Carotid Atherosclerosis Among Midlife Women.
Academic Article	Menstrual Cycle Hormone Changes in Women Traversing Menopause: Study of Women's Health Across the Nation.
Grant	Reprometabolic Syndrome Mediates Subfertility in Obesity
Grant	The Colorado Building Interdisciplinary Research Careers in Women's Health Program
Grant	Establishment of Regular Ovulation in Normal Menarche
Grant	Reproductive Hormonal Effects of Weight Loss in Women
Grant	Study of Women's Health Across the Nation (SWAN): New Jersey
Grant	REPRODUCTIVE PHYSIOLOGY OF OVARIAN FAILURE
Grant	Colorado Women's Reproductive Health Research Career Development Center
Grant	REPRODUCTIVE PHYSIOLOGY OF OVARIAN FAILURE
Academic Article	Sexual function in infertile women with polycystic ovary syndrome and unexplained infertility.
Academic Article	Effects of oral versus transdermal menopausal hormone treatments on self-reported sleep domains and their association with vasomotor symptoms in recently menopausal women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS).
Academic Article	Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS).
Academic Article	Prevalence of Complementary and Alternative Medicine and Herbal Remedy Use in Hispanic and Non-Hispanic White Women: Results from the Study of Women's Health Across the Nation.
Academic Article	Evidence for disruption of normal circadian cortisol rhythm in women with obesity.
Academic Article	Preconceptional antithyroid peroxidase antibodies, but not thyroid-stimulating hormone, are associated with decreased live birth rates in infertile women.
Academic Article	Induction of the LH Surge in Premenarchal Girls Confirms Early Maturation of the Hypothalamic-Pituitary-Ovarian Axis.
Academic Article	Religiosity and faith in relation to time to metabolic syndrome for Hispanic women in a multiethnic cohort of women-Findings from the Study of Women's Health Across the Nation (SWAN).
Academic Article	Reproductive Hormones and Subclinical Cardiovascular Disease in Midlife Women.
Academic Article	Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility.
Academic Article	Gestational Weight Gain in Women With Polycystic Ovary Syndrome: A Controlled Study.
Academic Article	Comparison of sonohysterography to hysterosalpingogram for tubal patency assessment in a multicenter fertility treatment trial among women with polycystic ovary syndrome.
Academic Article	Optimal treatment for women with a persisting pregnancy of unknown location, a randomized controlled trial: The ACT-or-NOT trial.
Academic Article	Menstrual Cycle Hormone Changes Associated with Reproductive Aging and How They May Relate to Symptoms.
Academic Article	The Disruptive Changes of Midlife: A Biopsychosocial Adventure.
Academic Article	Metabolic and cardiovascular effects of TX-001HR in menopausal women with vasomotor symptoms.
Academic Article	Associations Between Anti-Mullerian Hormone and Cardiometabolic Health in Reproductive Age Women Are Explained by Body Mass Index.
Grant	Pre-IVF treatment with a GnRH antagonist in women with endometriosis - A prospective double blind placebo controlled trial 2/3
Academic Article	Daily luteal serum and urinary hormone profiles in the menopause transition: Study of Women's Health Across the Nation.
Academic Article	Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women.
Academic Article	Heart fat and carotid artery atherosclerosis progression in recently menopausal women: impact of menopausal hormone therapy: The KEEPS trial.
Academic Article	Aromatase Inhibition Ameliorates Decreased LH Output Found in Obese Women.
Academic Article	Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation.
Academic Article	Androgenicity and fertility treatment in women with unexplained infertility.
Grant	Colorado Women's Reproductive Health Research Career Development Center
Grant	Study of Women's Health Across the Nation (SWAN): New Jersey
Grant	The Clinical Research/Reproductive Scientist Training Program (CREST)
Grant	The Study of Women Across a Lifespan: SWAN
Academic Article	Workshop on normal reference ranges for estradiol in postmenopausal women: commentary from The North American Menopause Society on low-dose vaginal estrogen therapy labeling.
Academic Article	Effect of the neurokinin 3 receptor antagonist fezolinetant on patient-reported outcomes in postmenopausal women with vasomotor symptoms: results of a randomized, placebo-controlled, double-blind, dose-ranging study (VESTA).
Academic Article	Short-term weight change and live birth among women with unexplained infertility and polycystic ovary syndrome undergoing ovulation induction.
Academic Article	Genome-wide association study meta-analysis identifies three novel loci for circulating anti-M?llerian hormone levels in women.
Academic Article	Menopausal status and observed differences in the gut microbiome in women with and without HIV infection.
Academic Article	Use of Hormone Therapy in Women with Early Menopause and Premature Ovarian Insufficiency.
Grant	Charting the Path to Health in Midlife and Beyond: the Biology and Practice of Wellness
Academic Article	A randomised trial examining inflammatory signaling in acutely induced hyperinsulinemia and hyperlipidemia in normal weight women-the reprometabolic syndrome.
Academic Article	Gonadotropin response to insulin and lipid infusion reproduces the reprometabolic syndrome of obesity in eumenorrheic lean women: a randomized crossover trial.
Academic Article	Sleep Habits of Women With Infertility.
Academic Article	Menopause Is Associated With Immune Activation in Women With HIV.
Academic Article	Do Women Need Androgens Like a Fish Needs a Bicycle? A Review of the Literature and Clinical Guidelines.
Academic Article	Willingness of Women with Endometriosis Planning to Undergo IVF to Participate in a Randomized Clinical Trial and the Effects of the COVID-19 Pandemic on Potential Participation.
Academic Article	Effects of preconception lifestyle intervention in infertile women with obesity: The FIT-PLESE randomized controlled trial.
Academic Article	"It just seems like people are talking about menopause, but nobody has a solution": A qualitative exploration of menopause experiences and preferences for weight management among Black women.
Academic Article	Genome-wide association study meta-analysis identifies three novel loci for circulating anti-M?llerian hormone levels in women.
Academic Article	Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial.
Academic Article	Probability of Pregnancy With Mono vs Multiple Folliculogenesis in Women With Unexplained Infertility.
Academic Article	Sex Hormones, the Stool Microbiome, and Subclinical Atherosclerosis in Women With and Without HIV.
Academic Article	Moderate and increased physical activity is not detrimental to live birth rates among women with unexplained infertility and obesity.
Academic Article	"Weight loss is my goal and being healthy is my goal? I can get over the hot flashes": a qualitative exploration of menopausal transition experiences and preferences for weight management among White women.
Academic Article	A high-fat eucaloric diet induces reprometabolic syndrome of obesity in normal weight women.
Academic Article	The Fit After Baby randomized controlled trial: An mHealth postpartum lifestyle intervention for women with elevated cardiometabolic risk.
Grant	The Colorado Building Interdisciplinary Research Careers in Women's Health Program

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