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Search Results to Wells Alton Messersmith

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Messersmith, Wells

One or more keywords matched the following items that are connected to Messersmith, Wells

Item Type	Name
Academic Article	Stromal cell-derived factor 1a mediates resistance to mTOR-directed therapy in pancreatic cancer.
Academic Article	New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways.
Academic Article	A multicenter phase I trial of PX-866, an oral irreversible phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors.
Academic Article	Biomarker-driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer.
Academic Article	Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib.
Concept	Phosphatidylinositol 3-Kinases
Academic Article	A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.
Academic Article	Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Academic Article	Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
Academic Article	ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/?-Catenin, Notch and PI3K/Akt Signaling Pathways.
Academic Article	A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.
Academic Article	Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.
Concept	Class I Phosphatidylinositol 3-Kinases
Academic Article	Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer.

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Phosphatidylinositol 3 Kinases