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Search Results to Wells Alton Messersmith

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One or more keywords matched the following items that are connected to Messersmith, Wells

Item TypeName
Academic Article Phase I trial of bortezomib in combination with docetaxel in patients with advanced solid tumors.
Academic Article Binding of gefitinib, an inhibitor of epidermal growth factor receptor-tyrosine kinase, to plasma proteins and blood cells: in vitro and in cancer patients.
Academic Article In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent.
Academic Article The role of functional MR imaging in the assessment of tumor response after chemoembolization in patients with hepatocellular carcinoma.
Academic Article An in vivo platform for translational drug development in pancreatic cancer.
Academic Article Chemotherapy and regional therapy of hepatic colorectal metastases: expert consensus statement.
Academic Article Assessment of celecoxib pharmacodynamics in pancreatic cancer.
Academic Article Panitumumab, a monoclonal anti epidermal growth factor receptor antibody in colorectal cancer: another one or the one?
Academic Article Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer.
Academic Article Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.
Academic Article Targeting EGFR in colorectal cancer.
Academic Article Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors.
Academic Article KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection.
Academic Article [18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy.
Academic Article Antitumor effects and biomarkers of activity of AZD0530, a Src inhibitor, in pancreatic cancer.
Academic Article Efficacy and pharmacodynamic effects of bosutinib (SKI-606), a Src/Abl inhibitor, in freshly generated human pancreas cancer xenografts.
Academic Article TNF-blockade in patients with advanced hormone refractory prostate cancer.
Academic Article KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer.
Academic Article Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer.
Academic Article ACR Appropriateness Criteria: rectal cancer-metastatic disease at presentation.
Academic Article Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.
Academic Article Phase I safety, pharmacokinetic, and pharmacodynamic study of ENMD-2076, a novel angiogenic and Aurora kinase inhibitor, in patients with advanced solid tumors.
Academic Article A tolerability and pharmacokinetic study of adjuvant erlotinib and capecitabine with concurrent radiation in resected pancreatic cancer.
Academic Article Current status of SRC inhibitors in solid tumor malignancies.
Academic Article Promising targets and drugs in development for colorectal cancer.
Academic Article Longitudinal assessment of oxaliplatin-induced neuropathy.
Academic Article Development of novel targeted agents in the treatment of metastatic colorectal cancer.
Academic Article Phase I study of bosutinib, a src/abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors.
Academic Article Oxaliplatin-induced neuropathy in colorectal cancer.
Academic Article Phase I study of Rigosertib, an inhibitor of the phosphatidylinositol 3-kinase and Polo-like kinase 1 pathways, combined with gemcitabine in patients with solid tumors and pancreatic cancer.
Academic Article ALDH+ tumor-initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a ?-secretase inhibitor and irinotecan in colorectal cancer.
Academic Article A phase I study of sunitinib combined with modified FOLFOX6 in patients with advanced solid tumors.
Academic Article Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer.
Academic Article Stromal cell-derived factor 1a mediates resistance to mTOR-directed therapy in pancreatic cancer.
Academic Article The development of regorafenib and its current and potential future role in cancer therapy.
Academic Article Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models.
Academic Article Recent advances in the pharmacological treatment of colorectal cancer.
Academic Article Phase I trial of irinotecan, infusional 5-fluorouracil, and leucovorin (FOLFIRI) with erlotinib (OSI-774): early termination due to increased toxicities.
Academic Article Assessment of Epidermal Growth Factor Receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis.
Academic Article Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours.
Academic Article Novel targets in solid tumors: MEK inhibitors.
Academic Article Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors.
Academic Article Phase I study of troxacitabine administered by continuous infusion in subjects with advanced solid malignancies.
Academic Article No time to waste: decreasing patient wait times for chemotherapy administration using automated prioritization in an oncology pharmacy system.
Academic Article KRAS mutations and susceptibility to cetuximab and panitumumab in colorectal cancer.
Academic Article A phase I dose-escalation, safety and pharmacokinetic study of the 2-methoxyestradiol analog ENMD-1198 administered orally to patients with advanced cancer.
Academic Article Phase I trial of weekly trabectedin (ET-743) and gemcitabine in patients with advanced solid tumors.
Academic Article Phase I study of MGCD0103 given as a three-times-per-week oral dose in patients with advanced solid tumors.
Academic Article Novel agents in the treatment of metastatic colorectal cancer.
Academic Article A phase I study of EKB-569 in combination with capecitabine in patients with advanced colorectal cancer.
Academic Article Phase I trial of oxaliplatin, infusional 5-fluorouracil, and leucovorin (FOLFOX4) with erlotinib and bevacizumab in colorectal cancer.
Academic Article New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways.
Academic Article Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.
Academic Article A phase I, dose-escalation study of pomalidomide (CC-4047) in combination with gemcitabine in metastatic pancreas cancer.
Academic Article Recurrent pancreatic adenocarcinoma after pancreatic resection.
Academic Article Patient-derived tumour xenografts as models for oncology drug development.
Academic Article Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.
Academic Article A multicenter phase I trial of PX-866, an oral irreversible phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors.
Academic Article Phase 2 trial of concurrent bevacizumab and transhepatic arterial chemoembolization in patients with unresectable hepatocellular carcinoma.
Academic Article Biomarker-driven trial in metastatic pancreas cancer: feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer.
Academic Article A phase I study of sorafenib and vorinostat in patients with advanced solid tumors with expanded cohorts in renal cell carcinoma and non-small cell lung cancer.
Academic Article Common PIK3CA mutants and a novel 3' UTR mutation are associated with increased sensitivity to saracatinib.
Academic Article Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial.
Academic Article Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial.
Concept Biliary Tract Neoplasms
Concept Cancer Care Facilities
Concept Adrenal Cortex Neoplasms
Concept Breast Neoplasms, Male
Concept Anus Neoplasms
Concept Tumor Burden
Concept Esophageal Neoplasms
Concept Lung Neoplasms
Concept Rectal Neoplasms
Concept Tumor Suppressor Protein p53
Concept Prostatic Neoplasms
Concept Neoplasm Metastasis
Concept Uveal Neoplasms
Concept Biomarkers, Tumor
Concept Antigens, Neoplasm
Concept Neoplasms, Second Primary
Concept Colorectal Neoplasms
Concept Cancer Vaccines
Concept Pancreatic Neoplasms
Concept Neoplasm Proteins
Concept Neoplasm Staging
Concept Kidney Neoplasms
Concept Drug Resistance, Neoplasm
Concept Neoplasm Transplantation
Concept Stomach Neoplasms
Concept Tumor Cells, Cultured
Concept Head and Neck Neoplasms
Concept Lymphocytes, Tumor-Infiltrating
Concept Bile Duct Neoplasms
Concept Tumor Necrosis Factor-alpha
Concept Neoplasms
Concept Skin Neoplasms
Concept Colonic Neoplasms
Concept Cell Line, Tumor
Concept Gastrointestinal Neoplasms
Concept Neoplasm Recurrence, Local
Concept Intestinal Neoplasms
Concept RNA, Neoplasm
Concept Liver Neoplasms
Concept Neoplasm Invasiveness
Academic Article A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.
Academic Article Metaanalysis of survival, complications, and imaging response following chemotherapy-based transarterial therapy in patients with unresectable intrahepatic cholangiocarcinoma.
Academic Article Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Academic Article Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a ?-secretase inhibitor, in a preclinical colorectal explant model.
Academic Article A phase 1B study of dulanermin in combination with modified FOLFOX6 plus bevacizumab in patients with metastatic colorectal cancer.
Academic Article Phase I study of oral rigosertib (ON 01910.Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignancies.
Academic Article A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors.
Academic Article Colon cancer, version 3.2014.
Academic Article A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma.
Academic Article Anti-ma2 paraneoplastic encephalitis in association with recurrent cervical cancer.
Academic Article An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIa and potent anticancer agent.
Academic Article Panitumumab in the treatment of colon cancer: A biomarker dilemma.
Academic Article Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Academic Article Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.
Academic Article A Phase I, dose-finding study in patients with advanced solid malignancies of the oral ?-secretase inhibitor PF-03084014.
Academic Article Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer.
Academic Article Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
Academic Article A phase I study of PF-04449913, an oral hedgehog inhibitor, in patients with advanced solid tumors.
Academic Article ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/?-Catenin, Notch and PI3K/Akt Signaling Pathways.
Academic Article Apatinib: a promising oral antiangiogenic agent in the treatment of multiple solid tumors.
Academic Article Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors.
Academic Article A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors.
Academic Article Rectal Cancer, Version 2.2015.
Academic Article Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.
Academic Article A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
Academic Article A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.
Academic Article Targeting the WNT Signaling Pathway in Cancer Therapeutics.
Academic Article Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.
Academic Article Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.
Academic Article A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.
Academic Article Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma.
Academic Article Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers.
Academic Article Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer.
Academic Article A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer.
Academic Article Therapeutic Approaches to RAS Mutation.
Academic Article Phase 1 Study of ABT-751 in Combination With CAPIRI (Capecitabine and Irinotecan) and Bevacizumab in Patients With Advanced Colorectal Cancer.
Academic Article The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance.
Academic Article Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.
Academic Article Topoisomerase IIa mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.
Academic Article Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody-Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies.
Academic Article Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies.
Academic Article Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Academic Article Impact of Facility Type and Surgical Volume on 10-Year Survival in Patients Undergoing Hepatic Resection for Hepatocellular Carcinoma.
Academic Article Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C.
Academic Article Colon Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.
Academic Article Impact of neoadjuvant chemoradiation on perioperative outcomes in patients with rectal cancer.
Grant Evaluation of Src Inhibition in Pancreas Cancer
Grant Evaluation of BAY43-9006/Cetuximab in Colorectal Cancer
Grant Biomarker-Driven Src Inhibitor Studies in Colorectal Cancer Patients
Grant Evaluation of Oral EGFR Inhibitors in Colorectal Cancer
Academic Article Systemic Management of Colorectal Cancer.
Academic Article A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.
Academic Article Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics.
Academic Article Therapy of Small Cell Lung Cancer (SCLC) with a Topoisomerase-I-inhibiting Antibody-Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan.
Academic Article Patterns of Care for Locally Advanced Pancreatic Adenocarcinoma Using the National Cancer Database.
Academic Article Cetuximab or Bevacizumab With First-Line Chemotherapy in Advanced KRAS Wild-Type Colorectal Cancer: No Difference, but Not the Same.
Academic Article Therapy of Advanced Non-Small-Cell Lung Cancer With an SN-38-Anti-Trop-2 Drug Conjugate, Sacituzumab Govitecan.
Academic Article Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.
Academic Article Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer.
Academic Article A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors.
Academic Article A Blueprint to Advance Colorectal Cancer Immunotherapies.
Academic Article Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors.
Academic Article Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
Academic Article A phase 1, dose-escalation study of PF-06664178, an anti-Trop-2/Aur0101 antibody-drug conjugate in patients with advanced or metastatic solid tumors.
Academic Article Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer.
Academic Article NCCN Guidelines Insights: Colon Cancer, Version 2.2018.
Academic Article Rectal Cancer, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.
Academic Article Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.
Academic Article Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models.
Academic Article A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.
Academic Article CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma.
Academic Article Antibody drug conjugates under investigation in phase I and phase II clinical trials for gastrointestinal cancer.
Academic Article Evaluation of TAK-264, an Antibody-Drug Conjugate in Pancreatic Cancer Cell Lines and Patient-Derived Xenograft Models.
Academic Article Correction to: 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018).
Academic Article Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.
Concept Tumor Microenvironment
Concept Response Evaluation Criteria in Solid Tumors
Concept Triple Negative Breast Neoplasms
Concept Neoplasm Grading
Academic Article Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.
Academic Article NCCN Guidelines Updates: Management of Metastatic Colorectal Cancer.
Academic Article Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer.
Academic Article A phase 1b dose escalation study of Wnt pathway inhibitor vantictumab in combination with nab-paclitaxel and gemcitabine in patients with previously untreated metastatic pancreatic cancer.
Academic Article Sacituzumab govitecan: breakthrough targeted therapy for triple-negative breast cancer.
Academic Article Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment.
Academic Article Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer.
Academic Article Wee1 Inhibition Enhances the Anti-Tumor Effects of Capecitabine in Preclinical Models of Triple-Negative Breast Cancer.
Academic Article Safety and Pharmacokinetics of CXCR4 Peptide Antagonist, LY2510924, in Combination with Durvalumab in Advanced Refractory Solid Tumors.
Academic Article Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors.
Academic Article First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer.
Academic Article NCCN Guidelines Insights: Rectal Cancer, Version 6.2020.
Academic Article Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer.
Academic Article Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors.
Academic Article Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide.
Academic Article Impact of neoadjuvant chemotherapy and stereotactic body radiation therapy (SBRT) on R0 resection rate for borderline resectable and locally advanced pancreatic cancer.
Academic Article Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.
Academic Article Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial.
Academic Article Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer.
Academic Article Innate Immune Checkpoint Inhibitors: The Next Breakthrough in Medical Oncology?
Academic Article Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers.
Academic Article Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.
Academic Article Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study.
Academic Article Transarterial Radioembolization in Patients With Unresectable Colorectal Cancer Liver Metastases.
Academic Article Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.
Academic Article Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study.
Academic Article Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma.
Academic Article Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L.
Academic Article Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study.
Academic Article ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.
Academic Article Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models.
Academic Article Improved Survival After Adjuvant Therapy in Locally Advanced Rectal Cancer Patients With Pathologic Complete Response.
Academic Article A Phase II Study Investigating Cabozantinib in Patients with Refractory Metastatic Colorectal Cancer (AGICC 17CRC01).
Academic Article A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas.
Academic Article Pulmonary metastasectomy is associated with survival after lung-only recurrence in pancreatic cancer.
Academic Article Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology.
Academic Article Correction: Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.
Academic Article Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Academic Article Advances in the management of pancreatic cancer.

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