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Search Results to Joshua Michael Thurman

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Thurman, Joshua

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Item Type	Name
Academic Article	Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice.
Academic Article	A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
Academic Article	Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.
Academic Article	Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.
Academic Article	Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
Academic Article	Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury.
Academic Article	Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.
Academic Article	Candidate inhibitors of porcine complement.
Academic Article	The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita.
Academic Article	New approaches to the treatment of dense deposit disease.
Academic Article	Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.
Academic Article	Alternative pathway of complement in children with diarrhea-associated hemolytic uremic syndrome.
Academic Article	Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2.
Academic Article	Renal inflammation: targeted iron oxide nanoparticles for molecular MR imaging in mice.
Academic Article	Aseptic injury to epithelial cells alters cell surface complement regulation in a tissue specific fashion.
Academic Article	An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.
Academic Article	The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.
Academic Article	Dynamic control of the complement system by modulated expression of regulatory proteins.
Academic Article	Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice.
Academic Article	Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury.
Academic Article	Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis.
Academic Article	Identification of a central role for complement in osteoarthritis.
Academic Article	Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells.
Academic Article	Factor friction: protective and pathogenic roles for complement factors in immune complex glomerulonephritis.
Academic Article	Noninvasive detection of complement activation through radiologic imaging.
Academic Article	IgM contributes to glomerular injury in FSGS.
Academic Article	The central role of the alternative complement pathway in human disease.
Academic Article	Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation.
Academic Article	Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction.
Academic Article	Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.
Academic Article	The alternative pathway of complement in disease: opportunities for therapeutic targeting.
Academic Article	Acute tubular necrosis is characterized by activation of the alternative pathway of complement.
Academic Article	The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
Academic Article	Binding of avian IgY to type VII collagen does not activate complement and leucocytes and fails to induce subepidermal blistering in mice.
Academic Article	Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart.
Academic Article	C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Academic Article	Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury.
Academic Article	Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice.
Academic Article	Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.
Academic Article	A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Academic Article	B cell subsets contribute to renal injury and renal protection after ischemia/reperfusion.
Academic Article	Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking.
Academic Article	IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity.
Academic Article	The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation.
Academic Article	Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.
Academic Article	Complement activation and toll-like receptor-2 signaling contribute to cytokine production after renal ischemia/reperfusion.
Academic Article	Role of the alternative and classical complement activation pathway in complement mediated killing against Streptococcus pneumoniae colony opacity variants during acute pneumococcal otitis media in mice.
Academic Article	Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Academic Article	Detection of complement activation using monoclonal antibodies against C3d.
Concept	Complement Inactivating Agents
Concept	Complement C4
Concept	Receptors, Complement 3b
Concept	Complement C5a
Concept	Complement C3b Inactivator Proteins
Concept	Complement C4a
Concept	Complement Membrane Attack Complex
Concept	Complement C4b-Binding Protein
Concept	Complement C2
Concept	Complement C9
Concept	Complement Factor B
Concept	Complement C3-C5 Convertases
Concept	Complement C3b
Concept	Complement Pathway, Classical
Concept	Complement Pathway, Mannose-Binding Lectin
Concept	Complement C3a
Concept	Complement Activation
Concept	Complement Pathway, Alternative
Concept	Complement C1q
Concept	Complement Factor D
Concept	Complement Factor H
Concept	Complement C5b
Concept	Receptors, Complement 3d
Concept	Complement Inactivator Proteins
Concept	Complement C5
Concept	Complement C3
Concept	Complement C6
Concept	Complement System Proteins
Concept	Receptors, Complement
Concept	Complement Fixation Tests
Concept	Complement C3d
Academic Article	A zebrafish model for uremic toxicity: role of the complement pathway.
Academic Article	Cyclosporine induces endothelial cell release of complement-activating microparticles.
Academic Article	Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis.
Academic Article	The role of the complement system in acute kidney injury.
Academic Article	C3 glomerulopathy: consensus report.
Academic Article	New anti-complement drugs: not so far away.
Academic Article	Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice.
Academic Article	Shiga toxin promotes podocyte injury in experimental hemolytic uremic syndrome via activation of the alternative pathway of complement.
Academic Article	Complement in kidney disease: core curriculum 2015.
Academic Article	The alternative complement component factor B regulates UV-induced oedema, systemic suppression of contact and delayed hypersensitivity, and mast cell infiltration into the skin.
Academic Article	Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques.
Academic Article	IgM exacerbates glomerular disease progression in complement-induced glomerulopathy.
Academic Article	Complement Activation in Patients with Focal Segmental Glomerulosclerosis.
Academic Article	The Complement System and Antibody-Mediated Transplant Rejection.
Academic Article	Annexin A2 Enhances Complement Activation by Inhibiting Factor H.
Academic Article	Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis.
Academic Article	Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood.
Academic Article	Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.
Academic Article	New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities.
Academic Article	Never make assumptions: the?complicated role of complement in urinary tract?infections.
Academic Article	Targeting the complement cascade: novel treatments coming down the pike.
Academic Article	All Things Complement.
Academic Article	Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.
Academic Article	Getting over our Immune-Complex - C5a receptor blockade is the answer.
Academic Article	Complement Alternative Pathway Deficiency in Recipients Protects Kidney Allograft From Ischemia/Reperfusion Injury and Alloreactive T Cell Response.
Academic Article	Many drugs for many targets: novel treatments for complement-mediated glomerular disease.
Grant	Complement and Ischemic Acute Renal Failure
Grant	Complement Activation and Renal Ischemia/Reperfusion Injury
Grant	Complement-mediated injury of the kidney: New mechanisms and novel therapies
Academic Article	The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune Diseases.
Grant	Immunologic Mechanisms of Progressive Glomerulosclerosis
Academic Article	Complement factor H-related proteins in IgA nephropathy-sometimes a gentle nudge does the trick.
Academic Article	Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.
Academic Article	Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins.
Academic Article	Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.
Academic Article	The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.
Academic Article	Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice.
Academic Article	SPECT/CT Imaging of Mycobacterium tuberculosis Infection with [125I]anti-C3d mAb.
Academic Article	Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy.
Academic Article	Endothelial Microparticles and Systemic Complement Activation in Patients With Chronic Kidney Disease.
Academic Article	Tissue-targeted complement therapeutics.
Academic Article	Complement Biomarkers of Hemolytic Uremic Syndrome-If Not One Thing, Maybe Another.
Grant	Effects of Complement on the Tumor Microenvironment in Lung Cancer
Academic Article	Complement Therapeutics in Autoimmune Disease.
Academic Article	The role of complement in antibody mediated transplant rejection.
Academic Article	Urine complement activation fragments are increased in patients with kidney injury after cardiac surgery.
Academic Article	Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
Academic Article	The Role of Complement in Organ Transplantation.
Academic Article	Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
Academic Article	Complement fragments are biomarkers of antibody-mediated endothelial injury.
Academic Article	Complement factor H-deficient mice develop spontaneous hepatic tumors.
Academic Article	Inflammation, immunity, and vascular remodeling in pulmonary hypertension; Evidence for complement involvement?
Academic Article	Complement and the Kidney: An Overview.
Academic Article	Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis.
Academic Article	Properdin Is a Key Player in Lysis of Red Blood Cells and Complement Activation on Endothelial Cells in Hemolytic Anemias Caused by Complement Dysregulation.
Academic Article	Complement-mediated kidney diseases.
Academic Article	Complement and Cancer-A Dysfunctional Relationship?
Academic Article	Rhabdomyolysis and complement-once again, epithelial cells take center stage.
Academic Article	Complement Detection in Mouse Kidneys by Immunofluorescence.
Academic Article	A clinical approach to children with C3 glomerulopathy.
Academic Article	Mechanisms of SARS-CoV-2-induced lung vascular disease: potential role of complement.
Academic Article	Natural antibody and complement activation characterize patients with idiopathic nephrotic syndrome.
Academic Article	Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation.
Academic Article	Marginal zone B cells acquire dendritic cell functions by trogocytosis.
Academic Article	Complement Activation Fragments Are Increased in Critically Ill Pediatric Patients with Severe AKI.
Academic Article	Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Academic Article	The complement system in pediatric acute kidney injury.
Academic Article	Factor H related proteins modulate complement activation on kidney cells.
Academic Article	The susceptibility of the kidney to alternative pathway activation-A hypothesis.
Academic Article	Alternative pathway diagnostics.
Academic Article	The complement alternative pathway in health and disease-activation or amplification?
Academic Article	Upregulation of complement proteins in lung cancer cells mediates tumor progression.
Academic Article	Urine Complement Factor Ba Is Associated with AKI in Critically Ill Children.
Academic Article	Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe.
Academic Article	MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity.
Academic Article	Complement inhibitors in pediatric kidney diseases: new therapeutic opportunities.
Academic Article	The role of complement in kidney disease.
Grant	The Alternative Pathway of Complement: A Potential Contributor to Adverse Outcomes in CKD

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Complement System Proteins