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Search Results to Joshua Michael Thurman

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One or more keywords matched the following items that are connected to Thurman, Joshua

Item TypeName
Academic Article Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice.
Academic Article A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
Academic Article Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.
Academic Article Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.
Academic Article Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
Academic Article Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury.
Academic Article Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.
Academic Article Candidate inhibitors of porcine complement.
Academic Article The alternative pathway of complement activation is critical for blister induction in experimental epidermolysis bullosa acquisita.
Academic Article New approaches to the treatment of dense deposit disease.
Academic Article Evidence for non-traditional activation of complement factor C3 during murine liver regeneration.
Academic Article Alternative pathway of complement in children with diarrhea-associated hemolytic uremic syndrome.
Academic Article Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2.
Academic Article Renal inflammation: targeted iron oxide nanoparticles for molecular MR imaging in mice.
Academic Article Aseptic injury to epithelial cells alters cell surface complement regulation in a tissue specific fashion.
Academic Article An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.
Academic Article The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.
Academic Article Dynamic control of the complement system by modulated expression of regulatory proteins.
Academic Article Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice.
Academic Article Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury.
Academic Article Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis.
Academic Article Identification of a central role for complement in osteoarthritis.
Academic Article Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells.
Academic Article Factor friction: protective and pathogenic roles for complement factors in immune complex glomerulonephritis.
Academic Article Noninvasive detection of complement activation through radiologic imaging.
Academic Article IgM contributes to glomerular injury in FSGS.
Academic Article The central role of the alternative complement pathway in human disease.
Academic Article Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation.
Academic Article Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction.
Academic Article Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.
Academic Article The alternative pathway of complement in disease: opportunities for therapeutic targeting.
Academic Article Acute tubular necrosis is characterized by activation of the alternative pathway of complement.
Academic Article The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
Academic Article Binding of avian IgY to type VII collagen does not activate complement and leucocytes and fails to induce subepidermal blistering in mice.
Academic Article Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart.
Academic Article C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Academic Article Oxidative stress renders retinal pigment epithelial cells susceptible to complement-mediated injury.
Academic Article Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice.
Academic Article Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.
Academic Article A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Academic Article B cell subsets contribute to renal injury and renal protection after ischemia/reperfusion.
Academic Article Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking.
Academic Article IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity.
Academic Article The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation.
Academic Article Complement alternative pathway activation in the autologous phase of nephrotoxic serum nephritis.
Academic Article Complement activation and toll-like receptor-2 signaling contribute to cytokine production after renal ischemia/reperfusion.
Academic Article Role of the alternative and classical complement activation pathway in complement mediated killing against Streptococcus pneumoniae colony opacity variants during acute pneumococcal otitis media in mice.
Academic Article Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Academic Article Detection of complement activation using monoclonal antibodies against C3d.
Concept Complement Inactivating Agents
Concept Complement C4
Concept Receptors, Complement 3b
Concept Complement C5a
Concept Complement C3b Inactivator Proteins
Concept Complement C4a
Concept Complement Membrane Attack Complex
Concept Complement C4b-Binding Protein
Concept Complement C2
Concept Complement C9
Concept Complement Factor B
Concept Complement C3-C5 Convertases
Concept Complement C3b
Concept Complement Pathway, Classical
Concept Complement Pathway, Mannose-Binding Lectin
Concept Complement C3a
Concept Complement Activation
Concept Complement Pathway, Alternative
Concept Complement C1q
Concept Complement Factor D
Concept Complement Factor H
Concept Complement C5b
Concept Receptors, Complement 3d
Concept Complement Inactivator Proteins
Concept Complement C5
Concept Complement C3
Concept Complement C6
Concept Complement System Proteins
Concept Receptors, Complement
Concept Complement Fixation Tests
Concept Complement C3d
Academic Article A zebrafish model for uremic toxicity: role of the complement pathway.
Academic Article Cyclosporine induces endothelial cell release of complement-activating microparticles.
Academic Article Complement factor B is the downstream effector of TLRs and plays an important role in a mouse model of severe sepsis.
Academic Article The role of the complement system in acute kidney injury.
Academic Article C3 glomerulopathy: consensus report.
Academic Article New anti-complement drugs: not so far away.
Academic Article Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice.
Academic Article Shiga toxin promotes podocyte injury in experimental hemolytic uremic syndrome via activation of the alternative pathway of complement.
Academic Article Complement in kidney disease: core curriculum 2015.
Academic Article The alternative complement component factor B regulates UV-induced oedema, systemic suppression of contact and delayed hypersensitivity, and mast cell infiltration into the skin.
Academic Article Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques.
Academic Article IgM exacerbates glomerular disease progression in complement-induced glomerulopathy.
Academic Article Complement Activation in Patients with Focal Segmental Glomerulosclerosis.
Academic Article The Complement System and Antibody-Mediated Transplant Rejection.
Academic Article Annexin A2 Enhances Complement Activation by Inhibiting Factor H.
Academic Article Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis.
Academic Article Properdin-Mediated C5a Production Enhances Stable Binding of Platelets to Granulocytes in Human Whole Blood.
Academic Article Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.
Academic Article New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities.
Academic Article Never make assumptions: the?complicated role of complement in urinary tract?infections.
Academic Article Targeting the complement cascade: novel treatments coming down the pike.
Academic Article All Things Complement.
Academic Article Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.
Academic Article Getting over our Immune-Complex - C5a receptor blockade is the answer.
Academic Article Complement Alternative Pathway Deficiency in Recipients Protects Kidney Allograft From Ischemia/Reperfusion Injury and Alloreactive T Cell Response.
Academic Article Many drugs for many targets: novel treatments for complement-mediated glomerular disease.
Grant Complement and Ischemic Acute Renal Failure
Grant Complement Activation and Renal Ischemia/Reperfusion Injury
Grant Complement-mediated injury of the kidney: New mechanisms and novel therapies
Academic Article The Evolving Landscape for Complement Therapeutics in Rheumatic and Autoimmune Diseases.
Grant Immunologic Mechanisms of Progressive Glomerulosclerosis
Academic Article Complement factor H-related proteins in IgA nephropathy-sometimes a gentle nudge does the trick.
Academic Article Complement Activation via a C3a Receptor Pathway Alters CD4+ T Lymphocytes and Mediates Lung Cancer Progression.
Academic Article Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins.
Academic Article Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.
Academic Article The relationship between complement C3 expression and the MUC5B genotype in pulmonary fibrosis.
Academic Article Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice.
Academic Article SPECT/CT Imaging of Mycobacterium tuberculosis Infection with [125I]anti-C3d mAb.
Academic Article Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy.
Academic Article Endothelial Microparticles and Systemic Complement Activation in Patients With Chronic Kidney Disease.
Academic Article Tissue-targeted complement therapeutics.
Academic Article Complement Biomarkers of Hemolytic Uremic Syndrome-If Not One Thing, Maybe Another.
Grant Effects of Complement on the Tumor Microenvironment in Lung Cancer
Academic Article Complement Therapeutics in Autoimmune Disease.
Academic Article The role of complement in antibody mediated transplant rejection.
Academic Article Urine complement activation fragments are increased in patients with kidney injury after cardiac surgery.
Academic Article Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.
Academic Article The Role of Complement in Organ Transplantation.
Academic Article Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
Academic Article Complement fragments are biomarkers of antibody-mediated endothelial injury.
Academic Article Complement factor H-deficient mice develop spontaneous hepatic tumors.
Academic Article Inflammation, immunity, and vascular remodeling in pulmonary hypertension; Evidence for complement involvement?
Academic Article Complement and the Kidney: An Overview.
Academic Article Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis.
Academic Article Properdin Is a Key Player in Lysis of Red Blood Cells and Complement Activation on Endothelial Cells in Hemolytic Anemias Caused by Complement Dysregulation.
Academic Article Complement-mediated kidney diseases.
Academic Article Complement and Cancer-A Dysfunctional Relationship?
Academic Article Rhabdomyolysis and complement-once again, epithelial cells take center stage.
Academic Article Complement Detection in Mouse Kidneys by Immunofluorescence.
Academic Article A clinical approach to children with C3 glomerulopathy.
Academic Article Mechanisms of SARS-CoV-2-induced lung vascular disease: potential role of complement.
Academic Article Natural antibody and complement activation characterize patients with idiopathic nephrotic syndrome.
Academic Article Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation.
Academic Article Marginal zone B cells acquire dendritic cell functions by trogocytosis.
Academic Article Complement Activation Fragments Are Increased in Critically Ill Pediatric Patients with Severe AKI.
Academic Article Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Academic Article The complement system in pediatric acute kidney injury.
Academic Article Factor H related proteins modulate complement activation on kidney cells.
Academic Article The susceptibility of the kidney to alternative pathway activation-A hypothesis.
Academic Article Alternative pathway diagnostics.
Academic Article The complement alternative pathway in health and disease-activation or amplification?
Academic Article Upregulation of complement proteins in lung cancer cells mediates tumor progression.
Academic Article Urine Complement Factor Ba Is Associated with AKI in Critically Ill Children.
Academic Article Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe.
Academic Article MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity.
Academic Article Complement inhibitors in pediatric kidney diseases: new therapeutic opportunities.
Academic Article The role of complement in kidney disease.
Grant The Alternative Pathway of Complement: A Potential Contributor to Adverse Outcomes in CKD

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