Item Type | Name |
Academic Article
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Mechanisms of cellular injury in interstitial lung disease.
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Academic Article
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Genetically determined resistance to listeriosis is associated with increased accumulation of inflammatory neutrophils and macrophages which have enhanced listericidal activity.
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Academic Article
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Mechanisms of release of granule enzymes from human neutrophils phagocytosing aggregated immunoglobulin. An electron microscopic study.
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Academic Article
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Secretion of lysosomal enzymes induced by immune complexes and complement.
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Academic Article
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Enhanced accumulation of inflammatory neutrophils and macrophages mediated by transfer of T cells from mice immunized with Listeria monocytogenes.
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Academic Article
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Pathologic mechanisms in neutrophil-mediated injury.
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Academic Article
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Mechanisms of release of constituents from rabbit platelets by antigen-antibody complexes and complement. II. Interaction of platelets with neutrophils.
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Academic Article
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An in vitro study of exocytosis of neutrophil granule enzymes in chronic granulomatous disease neutrophils.
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Academic Article
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Membrane receptors on neutrophils.
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Academic Article
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Interaction of cells with immune complexes: adherence, release of constituents, and tissue injury.
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Academic Article
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The effect of complement depletion on neutrophil migration in acute immunologic arthritis.
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Academic Article
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The adherence of leucocytes and platelets induced by fixed IgG antibody or complement.
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Academic Article
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Complement-dependent platelet and polymorphonuclear leukocyte reactions.
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Academic Article
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The immunologic release of constituents from neutrophil leukocytes. II. Mechanisms of release during phagocytosis, and adherence to nonphagocytosable surfaces.
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Academic Article
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The sequential release of granule constitutents from human neutrophils.
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Academic Article
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Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.
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Academic Article
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Oxidative metabolism of cord blood neutrophils: relationship to content and degranulation of cytoplasmic granules.
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Academic Article
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Mechanisms of acute lung injury.
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Academic Article
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Production and release of platelet-activating factor (PAF); dissociation from degranulation and superoxide production in the human neutrophil.
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Academic Article
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Killing of Listeria monocytogenes by inflammatory neutrophils and mononuclear phagocytes from immune and nonimmune mice.
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Academic Article
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A cell surface differentiation antigen involved in human neutrophil chemotaxis and degranulation.
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Academic Article
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The pulmonary response of C5 sufficient and deficient mice to immune complexes.
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Academic Article
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Killing of Listeria monocytogenes by human neutrophils and monocytes, but not by monocyte-derived macrophages.
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Academic Article
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Structure elucidation of platelet activating factor derived from human neutrophils.
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Academic Article
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Effect of dimethyl sulfoxide on the in vitro and in vivo bactericidal activity of human and mouse neutrophils and mononuclear phagocytes.
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Academic Article
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Platelet-activating factor (PAF) as a mediator of neutrophil-platelet interactions in inflammation.
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Academic Article
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Platelet-activating factor causes neutrophil accumulation and edema in rabbit lungs.
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Academic Article
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Neutrophil and platelet interactions in "allergic" and inflammatory reactions: a role for acetyl glyceryl ether phosphorylcholine (platelet-activating factor).
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Academic Article
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Chemotactic activity generated from the fifth component of complement by plasma kallikrein of the rabbit.
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Academic Article
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Mechanisms of exocytosis in phagocytic inflammatory cells. Parke-Davis Award Lecture.
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Academic Article
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A monoclonal antibody-inhibiting FMLP-induced chemotaxis of human neutrophils.
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Academic Article
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Pulmonary microvascular alterations and injury induced by complement fragments: synergistic effect of complement activation, neutrophil sequestration, and prostaglandins.
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Academic Article
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Absence of inflammatory lung injury in rabbits challenged intravascularly with complement-derived chemotactic factors.
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Academic Article
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Pulmonary intravascular sequestration of activated neutrophils: failure to induce light-microscopic evidence of lung injury in rabbits.
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Academic Article
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Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages.
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Academic Article
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Intracellular control of human neutrophil secretion. II. Stimulus specificity of desensitization induced by six different soluble and particulate stimuli.
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Academic Article
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Human neutrophil-derived platelet activating factor.
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Academic Article
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Apoptotic neutrophils are phagocytosed by fibroblasts with participation of the fibroblast vitronectin receptor and involvement of a mannose/fucose-specific lectin.
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Academic Article
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Properties of LTA4 synthase in human neutrophil preparations.
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Academic Article
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Migration-associated volume changes in neutrophils facilitate the migratory process in vitro.
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Academic Article
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Leukotriene C4 formation by transcellular biosynthesis.
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Academic Article
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Chemotactic activity in bronchoalveolar lavage fluid from patients with adult respiratory distress syndrome.
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Academic Article
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Role of alveolar macrophages in endotoxin-induced neutrophilic alveolitis in rats.
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Academic Article
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Complement independent lipopolysaccharide (LPS) induced hypotension and disseminated intravascular coagulation: a correlation of LPS structure with in vivo and in vitro biological activities.
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Academic Article
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Cellular mediators of immunological tissue injury.
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Academic Article
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Activation of rat mast cells by low molecular weight stimuli.
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Academic Article
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Time-dependent utilization of platelet arachidonic acid by the neutrophil in formation of 5-lipoxygenase products in platelet-neutrophil co-incubations.
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Academic Article
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The ability of chemotactic factors to induce lysosomal enzyme release. I. The characteristics of the release, the importance of surfaces and the relation of enzyme release to chemotactic responsiveness.
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Academic Article
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The release of granule enzymes from human neutrophils stimulated by aggregated immunoglobulins of different classes and subclasses.
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Academic Article
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Neutrophils increase volume during migration in vivo and in vitro.
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Academic Article
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The immunologic release of constituents from neutrophil leukocytes. I. The role of antibody and complement on nonphagocytosable surfaces or phagocytosable particles.
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Academic Article
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Immunological induction of increased vascular permeability. I. A rabbit passive cutaneous anaphylactic reaction requiring complement, platelets, and neutrophils.
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Academic Article
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Respiratory burst enzyme in human neutrophils. Evidence for multiple mechanisms of activation.
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Academic Article
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A monoclonal antibody inhibiting human neutrophil chemotaxis and degranulation.
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Academic Article
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Resolution of pulmonary inflammation.
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Academic Article
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Neutrophil-endothelial cell interactions. Modulation of neutrophil adhesiveness induced by complement fragments C5a and C5a des arg and formyl-methionyl-leucyl-phenylalanine in vitro.
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Academic Article
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A complement to host defence.
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Academic Article
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Pharmacological modulation of human platelet leukotriene C4-synthase.
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Academic Article
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Accumulation of platelets at sites of antigen-antibody-mediated injury: a possible role for IgE antibody and mast cells.
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Academic Article
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Age-dependent neutrophil and blood flow responsiveness in acute pulmonary inflammation in rabbits.
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Academic Article
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Purification and characterization of an antigen involved in neutrophil chemotaxis and degranulation using a monoclonal antibody.
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Academic Article
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Reversible membrane association of neutrophil 5-lipoxygenase is accompanied by retention of activity and a change in substrate specificity.
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Academic Article
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The microvasculature in inflammation.
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Academic Article
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In vivo clearance and tissue distribution of C5a and C5a des arginine complement fragments in rabbits.
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Academic Article
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Neutrophil chemotaxis in response to surface-bound C5A.
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Academic Article
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Effects of neutrophil depletion and repletion on PAF-induced hyperresponsiveness of canine trachea.
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Academic Article
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Effects of the aqueous fraction of the ethanol extract of the leaves of Cissampelos sympodialis Eichl. in human neutrophils.
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Academic Article
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The mechanism of internalization of platelet-activating factor in activated human neutrophils. Enhanced transbilayer movement across the plasma membrane.
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Academic Article
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Platelet-activating factor causes neutrophil accumulation and neutrophil-mediated increased vascular permeability in canine trachea.
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Academic Article
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Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils.
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Academic Article
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Linkage of azurophil granule secretion in neutrophils to chloride ion transport and endosomal transcytosis.
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Academic Article
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Differential metabolism of exogenous and endogenous arachidonic acid in human neutrophils.
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Academic Article
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Neutrophil sequestration and migration in localized pulmonary inflammation. Capillary localization and migration across the interalveolar septum.
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Academic Article
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Differential roles for alpha(M)beta(2) integrin clustering or activation in the control of apoptosis via regulation of akt and ERK survival mechanisms.
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Academic Article
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Neutrophil maturation and activation determine anatomic site of clearance from circulation.
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Academic Article
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The effect of complement depletion on experimental tissue injury.
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Academic Article
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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
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Academic Article
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Additive effect of intravascular complement activation and brief episodes of hypoxia in producing increased permeability in the rabbit lung.
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Academic Article
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Cytophilic properties of IgA to human neutrophils.
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Academic Article
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Acute immunologic arthritis in rabbits.
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Academic Article
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Neutrophil kinetics in the pulmonary microcirculation during acute inflammation.
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Academic Article
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Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP.
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Academic Article
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Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5.
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Academic Article
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The matrix degrades, neutrophils invade.
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Academic Article
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Control of local blood flow in pulmonary inflammation: role for neutrophils, PAF, and thromboxane.
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Academic Article
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Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A.
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Academic Article
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Fibronectin fragments containing the RGDS cell-binding domain mediate monocyte migration into the rabbit lung. A potential mechanism for C5 fragment-induced monocyte lung accumulation.
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Academic Article
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NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A.
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Academic Article
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Effects of acrolein on leukotriene biosynthesis in human neutrophils.
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Academic Article
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Bacterial lipopolysaccharide enhances chemoattractant-induced elastase secretion by human neutrophils.
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Academic Article
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It's much more than just pretty pictures.
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Academic Article
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Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse.
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Academic Article
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Adherence of neutrophils to cultured human microvascular endothelial cells. Stimulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family.
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Academic Article
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Platelets and endothelial cells contribute to the production of LTC4 by transcellular metabolism with neutrophils.
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Academic Article
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PPAR? activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease.
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Academic Article
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Role of p38 mitogen-activated protein kinase in a murine model of pulmonary inflammation.
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Academic Article
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Transcellular sulfidopeptide leukotriene biosynthetic capacity of vascular cells.
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Academic Article
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Endotoxin-pretreated neutrophils increase pulmonary vascular permeability in dogs.
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Academic Article
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Neutrophil clearance: when the party is over, clean-up begins.
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Academic Article
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Selective secretion of azurophil granule contents induced by monovalent cation ionophores in human neutrophils: evidence for direct ionophore effects on the granule membrane.
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Academic Article
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Intracellular control of human neutrophil secretion. I. C5a-induced stimulus-specific desensitization and the effects of cytochalasin B.
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Academic Article
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Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils.
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Academic Article
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The release of a platelet-activating factor by stimulated rabbit neutrophils.
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Academic Article
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Resolution of lung inflammation by CD44.
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Academic Article
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Complement fragments, alveolar macrophages, and alveolitis.
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Academic Article
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Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide.
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Academic Article
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Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.
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Academic Article
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PAF antagonists: different effects on platelets, neutrophils, guinea pig ileum and PAF-induced vasodilation in isolated rat lung.
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Academic Article
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Neutrophil-mediated pulmonary vascular injury. Synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lung.
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Academic Article
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Association of an abnormality of neutrophil chemotaxis in human periodontal disease with a cell surface protein.
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Academic Article
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The effect of neutrophil migration and prolonged neutrophil contact on epithelial permeability.
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Academic Article
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A cytosolic phospholipase in human neutrophils that hydrolyzes arachidonoyl-containing phosphatidylcholine.
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Academic Article
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Epithelial permeability produced by phagocytosing neutrophils in vitro.
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Academic Article
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The requirement for polymorphonuclear leukocytes in the late asthmatic response and heightened airways reactivity in an animal model.
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Academic Article
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Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. Secretion of granule constituents and increased oxidation of glucose.
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Academic Article
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Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils.
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Academic Article
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Airways hyperreactivity and inflammation produced by aerosolization of human C5A des arg.
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Academic Article
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Lung vascular injury induced by chemotactic factors: enhancement by bacterial endotoxins.
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Academic Article
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The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit.
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Academic Article
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Effects of shear stress on adhesive interaction between neutrophils and cultured endothelial cells.
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Academic Article
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Enhancement of immunologically induced granule exocytosis from neutrophils by cytochalasin B.
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Academic Article
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Biologial effects of the human complement fragments C5a and C5ades Arg on neutrophil function.
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Academic Article
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The pulmonary response of C5 sufficient and deficient mice to Pseudomonas aeruginosa.
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Academic Article
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Lung inflammation induced by complement-derived chemotactic fragments in the alveolus.
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Academic Article
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Chemotactic activity of C5ades Arg: evidence of a requirement for an anionic peptide 'helper factor' and inhibition by a cationic protein in serum from patients with systemic lupus erythematosus.
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Academic Article
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Enhancement of the chemotactic activity of human C5a des Arg by an anionic polypeptide ("cochemotaxin") in normal serum and plasma.
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Academic Article
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Disparate role of the beta 2-integrin CD18 in the local accumulation of neutrophils in pulmonary and cutaneous inflammation in the rabbit.
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Academic Article
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Paradoxic effect of ibuprofen on neutrophil accumulation in pulmonary and cutaneous inflammation.
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Academic Article
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Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.
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Academic Article
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Eosinophil 15-lipoxygenase is a leukotriene A4 synthase.
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Academic Article
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Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils.
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Academic Article
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Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis.
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Academic Article
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Neutrophil-platelet adhesion: relative roles of platelet P-selectin and neutrophil beta2 (DC18) integrins.
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Academic Article
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p38 mitogen-activated protein kinase-dependent and -independent intracellular signal transduction pathways leading to apoptosis in human neutrophils.
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Academic Article
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Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis.
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Academic Article
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Dampening inflammation.
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Academic Article
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An intracellular signaling pathway linking lipopolysaccharide stimulation to cellular responses of the human neutrophil: the p38 MAP kinase cascade and its functional significance.
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Academic Article
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A novel glutathione containing eicosanoid (FOG7) chemotactic for human granulocytes.
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Academic Article
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Tumor necrosis factor-alpha activation of the c-Jun N-terminal kinase pathway in human neutrophils. Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases apoptosis.
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Academic Article
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Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases.
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Academic Article
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Interaction of platelets and neutrophils in the generation of sulfidopeptide leukotrienes.
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Academic Article
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Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils.
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Academic Article
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Resolution of inflammation. A perspective.
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Academic Article
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Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte.
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Academic Article
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Interaction between chemoattractants and bacterial lipopolysaccharide in the induction and enhancement of neutrophil adhesion.
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Academic Article
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The subcellular distribution of platelet-activating factor in stimulated human neutrophils.
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Academic Article
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Interactions between neutrophils and platelets.
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Academic Article
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Transcellular biosynthesis of sulfidopeptide leukotrienes during receptor-mediated stimulation of human neutrophil/platelet mixtures.
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Academic Article
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111Indium-labeled neutrophil migration into the lungs of bleomycin-treated rabbits assessed noninvasively by external scintigraphy.
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Academic Article
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Development and characterization of a lung-protective method of bone marrow transplantation in the mouse.
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Academic Article
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Neutrophil kinetics in the pulmonary microcirculation. Effects of pressure and flow in the dependent lung.
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Academic Article
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Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism.
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Academic Article
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Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA.
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Academic Article
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Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity.
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Academic Article
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TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
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Academic Article
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Cessation of neutrophil influx in C5a-induced acute experimental arthritis is associated with loss of chemoattractant activity from the joint space.
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Academic Article
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Neutrophils regulate tissue Neutrophilia in inflammation via the oxidant-modified lipid lysophosphatidylserine.
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Academic Article
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The intracellular retention of newly synthesized platelet-activating factor.
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Academic Article
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Induction of lysosomal enzyme secretion by alveolar macrophages in response to the purified complement fragments C5a and C5a des-arg.
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Academic Article
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Phospholipase A2 contamination of cobra venom factor preparations. Biologic role in complement-dependent in vivo reactions and inactivation with p-bromophenacyl bromide.
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Academic Article
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Tissue injury in inflammation. Oxidants, proteinases, and cationic proteins.
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Academic Article
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Neutrophil transmigration triggers repair of the lung epithelium via beta-catenin signaling.
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Academic Article
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Physiological neutrophil sequestration in the lung: visual evidence for localization in capillaries.
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Academic Article
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Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.
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Concept
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Neutrophils
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Concept
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Neutrophil Activation
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Concept
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Neutrophil Infiltration
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Academic Article
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Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease.
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Grant
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NEUTROPHIL APOPTOSIS IN RESOLUTION OF INFLAMMATION
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Grant
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Ether Lipids, Elcosanoids, and Lung Cell Pathophysiology
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Grant
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CONTROL OF NEUTROPHIL FUNCTION BY VOLUME
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Grant
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RELEASE OF INJURIOUS CONSTITUENTS FROM CELLS
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Academic Article
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Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.
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Grant
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Neutrophil Nox2 controls mononuclear cell functions in inflammation; role in CGD
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Academic Article
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Heightened turnover and failed maturation of monocyte-derived macrophages in murine chronic granulomatous disease.
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