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Search Results to Dennis R Roop

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Roop, Dennis

One or more keywords matched the following items that are connected to Roop, Dennis

Item Type	Name
Academic Article	Proto-oncogene expression during two-stage carcinogenesis in mouse skin.
Academic Article	Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.
Academic Article	Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene.
Academic Article	Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting.
Academic Article	Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression.
Academic Article	Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Academic Article	Development of transgenic mouse models of skin carcinogenesis: potential applications.
Academic Article	Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.
Academic Article	Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Academic Article	Characterization of loricrin regulation in vitro and in transgenic mice.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Academic Article	Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation.
Academic Article	Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Academic Article	c-Myc and epidermal stem cell fate determination.
Academic Article	Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Academic Article	The malignant conversion step of mouse skin carcinogenesis.
Academic Article	Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Academic Article	SKI knockdown inhibits human melanoma tumor growth in vivo.
Academic Article	Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis.
Academic Article	p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
Academic Article	Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.
Academic Article	Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15.
Academic Article	Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element.
Academic Article	TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Academic Article	Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
Academic Article	Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.
Academic Article	Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.
Academic Article	Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Academic Article	Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Academic Article	Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression.
Academic Article	The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes.
Academic Article	An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue.
Academic Article	The effect of c-myc on stem cell fate influences skin tumor phenotype.
Academic Article	Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.
Concept	Oncogene Proteins, Viral
Concept	Proto-Oncogene Proteins c-sis
Concept	Proto-Oncogene Proteins c-myc
Concept	Oncogene Proteins v-fos
Concept	Oncogenes
Concept	Proto-Oncogenes
Concept	Oncogene Protein p21(ras)
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Proto-Oncogene Proteins c-jun
Concept	Proto-Oncogene Proteins p21(ras)
Concept	Proto-Oncogene Proteins c-fos
Concept	Proto-Oncogene Proteins
Concept	Proto-Oncogene Proteins c-kit
Academic Article	Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
Academic Article	Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.
Academic Article	Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors.
Academic Article	XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.
Academic Article	MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Grant	INDUCIBLE MOUSE MODELS FOR SKIN AND HEAD AND NECK CANCER
Grant	Targeting Oncogene Expression to Skin in Transgenic Mice
Grant	TARGETING HUMAN PAPILLOMA VIRUS GENE EXPRESSION IN MICE
Academic Article	INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

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