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Search Results to Dennis R Roop

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One or more keywords matched the following items that are connected to Roop, Dennis

Item TypeName
Academic Article Proto-oncogene expression during two-stage carcinogenesis in mouse skin.
Academic Article Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.
Academic Article Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene.
Academic Article Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting.
Academic Article Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression.
Academic Article Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Academic Article Development of transgenic mouse models of skin carcinogenesis: potential applications.
Academic Article Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.
Academic Article Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Academic Article Characterization of loricrin regulation in vitro and in transgenic mice.
Academic Article 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Academic Article Deregulated expression of c-Myc depletes epidermal stem cells.
Academic Article Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation.
Academic Article Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Academic Article c-Myc and epidermal stem cell fate determination.
Academic Article Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Academic Article The malignant conversion step of mouse skin carcinogenesis.
Academic Article Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Academic Article SKI knockdown inhibits human melanoma tumor growth in vivo.
Academic Article Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis.
Academic Article p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
Academic Article Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.
Academic Article Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15.
Academic Article Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element.
Academic Article TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article 12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Academic Article Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
Academic Article Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.
Academic Article Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.
Academic Article Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Academic Article Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Academic Article Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression.
Academic Article The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes.
Academic Article An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue.
Academic Article The effect of c-myc on stem cell fate influences skin tumor phenotype.
Academic Article Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.
Concept Oncogene Proteins, Viral
Concept Proto-Oncogene Proteins c-sis
Concept Proto-Oncogene Proteins c-myc
Concept Oncogene Proteins v-fos
Concept Oncogenes
Concept Proto-Oncogenes
Concept Oncogene Protein p21(ras)
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins c-fos
Concept Proto-Oncogene Proteins
Concept Proto-Oncogene Proteins c-kit
Academic Article Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
Academic Article Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.
Academic Article Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors.
Academic Article XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.
Academic Article MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Grant INDUCIBLE MOUSE MODELS FOR SKIN AND HEAD AND NECK CANCER
Grant Targeting Oncogene Expression to Skin in Transgenic Mice
Grant TARGETING HUMAN PAPILLOMA VIRUS GENE EXPRESSION IN MICE
Academic Article INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

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