Connection

Contact Us
If you have any questions or feedback please contact us.

Search Results to Dennis R Roop

This is a "connection" page, showing the details of why an item matched the keywords from your search.

Search Results

Roop, Dennis

One or more keywords matched the following items that are connected to Roop, Dennis

Item Type	Name
Academic Article	Proto-oncogene expression during two-stage carcinogenesis in mouse skin.
Academic Article	Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments.
Academic Article	Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture.
Academic Article	Structural features of epidermal keratin filaments reassembled in vitro.
Academic Article	Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.
Academic Article	Genetic disorders of keratin: are scarring alopecias a sub-set?
Academic Article	Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
Academic Article	Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.
Academic Article	Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene.
Academic Article	Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.
Academic Article	Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion.
Academic Article	Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo.
Academic Article	Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development.
Academic Article	Multiple defects and perinatal death in mice deficient in follistatin.
Academic Article	Dissecting molecular carcinogenesis: development of transgenic mouse models by epidermal gene targeting.
Academic Article	Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression.
Academic Article	Expression patterns of loricrin in various species and tissues.
Academic Article	Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis.
Academic Article	Multistage skin carcinogenesis in transgenic mice.
Academic Article	Keratin gene expression in mouse epidermis and cultured epidermal cells.
Academic Article	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.
Academic Article	Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Academic Article	A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis.
Academic Article	Langerhans cells in the TGF beta 1 null mouse.
Academic Article	A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice.
Academic Article	Development of transgenic mouse models of skin carcinogenesis: potential applications.
Academic Article	Differentiation and tumor response to retinobenzoic acid RE-80 in a malignant conversion model.
Academic Article	Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.
Academic Article	Transgenic models of skin diseases.
Academic Article	The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression.
Academic Article	Ex vivo and in vivo adenovirus-mediated gene therapy strategies induce a systemic anti-tumor immune defence in the B16 melanoma model.
Academic Article	Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Academic Article	Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function.
Academic Article	Full-thickness skin grafts from flaky skin mice to nude mice: maintenance of the psoriasiform phenotype.
Academic Article	Characterization of loricrin regulation in vitro and in transgenic mice.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Academic Article	Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains.
Academic Article	Delayed wound healing in keratin 6a knockout mice.
Academic Article	NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis.
Academic Article	Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders.
Academic Article	An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy.
Academic Article	K14-GLp65 transactivator induces transgene expression in embryonic epidermis.
Academic Article	Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors.
Academic Article	Quasi-normal cornified cell envelopes in loricrin knockout mice imply the existence of a loricrin backup system.
Academic Article	Early expression of type I K13 keratin in the progression of mouse skin papillomas.
Academic Article	In utero activation of K5.CrePR1 induces gene deletion.
Academic Article	Interaction between dermal papilla and bulge: the rhino mouse mutation as a model system.
Academic Article	Epidermal differentiation: transgenic/knockout mouse models reveal genes involved in stem cell fate decisions and commitment to differentiation.
Academic Article	Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Academic Article	Multistage epidermal carcinogenesis in transgenic mice: cooperativity and paradox.
Academic Article	Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment.
Academic Article	Transgenic mouse models provide new insights into the role of p63 in epidermal development.
Academic Article	c-Myc and epidermal stem cell fate determination.
Academic Article	p63 is the molecular switch for initiation of an epithelial stratification program.
Academic Article	p63 and epithelial appendage development.
Academic Article	Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes.
Academic Article	p63 is a p53 homologue required for limb and epidermal morphogenesis.
Academic Article	Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.
Academic Article	The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4.
Academic Article	p63 induces key target genes required for epidermal morphogenesis.
Academic Article	Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function.
Academic Article	Mechanisms regulating epithelial stratification.
Academic Article	An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.
Academic Article	Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Academic Article	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.
Academic Article	The malignant conversion step of mouse skin carcinogenesis.
Academic Article	Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.
Academic Article	Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate.
Academic Article	The use of cDNA clones and monospecific antibodies as probes to monitor keratin gene expression.
Academic Article	Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Academic Article	A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.
Academic Article	DeltaNp63 knockdown mice: A mouse model for AEC syndrome.
Academic Article	The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences.
Academic Article	A procedure for the culture of hair follicles as functionally intact organoids.
Academic Article	Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins.
Academic Article	Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
Academic Article	Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis.
Academic Article	SKI knockdown inhibits human melanoma tumor growth in vivo.
Academic Article	Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis.
Academic Article	Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis.
Academic Article	p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
Academic Article	Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation.
Academic Article	Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.
Academic Article	Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage.
Academic Article	WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse.
Academic Article	Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits.
Academic Article	Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein.
Academic Article	Transgenic mice expressing a mutant form of loricrin reveal the molecular basis of the skin diseases, Vohwinkel syndrome and progressive symmetric erythrokeratoderma.
Academic Article	Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo.
Academic Article	Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.
Academic Article	Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.
Academic Article	Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium.
Academic Article	A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes.
Academic Article	Myoepitheliomas in inbred laboratory mice.
Academic Article	A fitness model for melanoma-initiating cells.
Academic Article	Aurora kinase-A deficiency during skin development impairs cell division and stratification.
Academic Article	Generation of functional multipotent keratinocytes from mouse induced pluripotent stem cells.
Academic Article	Assignment of the Ly-6--Ril-1--Sis--H-30--Pol-5/Xmmv-72--Ins-3--Krt-1--Int-1 --Gdc-1 region to mouse chromosome 15.
Academic Article	Genetic manipulation of keratinocyte stem cells with lentiviral vectors.
Academic Article	The expression and modulation of IL-1 alpha in murine keratinocytes.
Academic Article	Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures.
Academic Article	Expression of keratins in mouse vaginal epithelium.
Academic Article	Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution.
Academic Article	TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article	Hair follicle companion layer: reacquainting an old friend.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Academic Article	Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network.
Academic Article	Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
Academic Article	Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
Academic Article	Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3.
Academic Article	Functional analysis of activins during mammalian development.
Academic Article	IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis.
Academic Article	Development of transgenic mice that inducibly express an active form of c-Src in the epidermis.
Academic Article	Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.
Academic Article	Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors.
Academic Article	Inducible mouse models for inherited skin diseases: implications for skin gene therapy.
Academic Article	Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.
Academic Article	Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function.
Academic Article	Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.
Academic Article	Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Academic Article	Adenovirus-mediated ex vivo immunogene and in vivo combination gene therapy strategies induce a systemic anti-tumor immune defense in the mouse B16 melanoma model.
Academic Article	P63 deficiency: a failure of lineage commitment or stem cell maintenance?
Academic Article	Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Academic Article	Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression.
Academic Article	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.
Academic Article	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.
Academic Article	p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.
Academic Article	Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.
Academic Article	Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders.
Academic Article	Keratin 6 is not essential for mammary gland development.
Academic Article	Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis.
Academic Article	Regulated cutaneous gene delivery: the skin as a bioreactor.
Academic Article	An unexpected role for keratin 10 end domains in susceptibility to skin cancer.
Academic Article	The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes.
Academic Article	Double-inducible gene activation system for caspase 3 and 9 in epidermis.
Academic Article	Asymmetric cell division in skin development: a new look at an old observation.
Academic Article	Mouse models in preclinical studies for pachyonychia congenita.
Academic Article	TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis.
Academic Article	Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes.
Academic Article	p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.
Academic Article	Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas.
Academic Article	Treasure or artifact: a decade of p63 research speaks for itself.
Academic Article	Aberrant differentiation in mouse skin carcinogenesis.
Academic Article	Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.
Academic Article	Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration.
Academic Article	Horizontal basal cells are multipotent progenitors in normal and injured adult olfactory epithelium.
Academic Article	Genetically engineered mouse models for skin research: taking the next step.
Academic Article	An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue.
Academic Article	Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.
Academic Article	Abnormal expression and processing of keratins in pupoid fetus (pf/pf) and repeated epilation (Er/Er) mutant mice.
Academic Article	Keratin expression in mouse epidermal tumors.
Academic Article	The effect of c-myc on stem cell fate influences skin tumor phenotype.
Academic Article	Are stem cell niches shared for skin cancers?
Academic Article	Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.
Academic Article	Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.
Academic Article	Consequences of exposure to initiating levels of carcinogens in vitro and in vivo: altered differentiation and growth, mutations, and transformation.
Academic Article	Nrf2 links epidermal barrier function with antioxidant defense.
Academic Article	Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance.
Academic Article	ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.
Academic Article	A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis.
Academic Article	Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia.
Academic Article	Cultivation of murine hair follicles as organoids in a collagen matrix.
Academic Article	Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.
Academic Article	The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit.
Concept	Mice, Inbred CBA
Concept	Mice, Inbred BALB C
Concept	Mice, Inbred NOD
Concept	Mice, Inbred A
Concept	Mice, Hairless
Concept	Mice, Knockout
Concept	Mice, Inbred C3H
Concept	Mice, Nude
Concept	Mice, SCID
Concept	Mice, Inbred Strains
Concept	Mice
Concept	Mice, Mutant Strains
Concept	Mice, Inbred ICR
Concept	Mice, Inbred C57BL
Concept	Mice, Transgenic
Academic Article	Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
Academic Article	Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.
Academic Article	Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.
Academic Article	Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.
Academic Article	Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype.
Academic Article	XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.
Academic Article	MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Academic Article	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Academic Article	Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75.
Academic Article	Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for?the Loss of Loricrin.
Academic Article	Proteomic Analysis of Loricrin Knockout Mouse Epidermis.
Academic Article	Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Academic Article	Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.
Grant	REGULATION AND FUNCTION OF KERATINS IN THE EPIDERMIS
Grant	The consequences of loricrin deficiency on epidermal barrier function
Grant	INDUCIBLE MOUSE MODELS FOR SKIN AND HEAD AND NECK CANCER
Grant	TESTING GENE THERAPY FOR EPIDERMOLYSIS BULLOSA SIMPLEX
Grant	Regulation and Function of Keratins in the Epidermis
Grant	Targeting Oncogene Expression to Skin in Transgenic Mice
Grant	TARGETING HUMAN PAPILLOMA VIRUS GENE EXPRESSION IN MICE
Grant	Molecular Mechanisms of Skin and Appendage Development
Grant	Testing the Therapeutic Potential of iPS Cells for Inherited Skin Diseases
Grant	REGULATION AND FUNCTION OF A MAJOR CELL ENVELOPE PROTEIN
Academic Article	INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.
Academic Article	Loricrin Confers Photoprotective Function against?UVB in Corneocytes.
Academic Article	Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata.
Academic Article	Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging.
Academic Article	NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy.
Academic Article	Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft.
Academic Article	"Structural imprinting" of the cutaneous immune effector function.

Search Criteria

Mice