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Search Results to Dennis R Roop

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Roop, Dennis

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Item Type	Name
Academic Article	Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments.
Academic Article	Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture.
Academic Article	Structural features of epidermal keratin filaments reassembled in vitro.
Academic Article	Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies.
Academic Article	Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens.
Academic Article	Genetic disorders of keratin: are scarring alopecias a sub-set?
Academic Article	Defects in the barrier.
Academic Article	A mutational hot spot in keratin 10 (KRT 10) in patients with epidermolytic hyperkeratosis.
Academic Article	Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.
Academic Article	Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.
Academic Article	Mutations in the 1A domain of keratin 9 in patients with epidermolytic palmoplantar keratoderma.
Academic Article	Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene.
Academic Article	Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion.
Academic Article	Low frequency of codon 61 Ha-ras mutations and lack of keratin 13 expression in 7,12-dimethylbenz[a]-anthracene-induced hamster skin tumors.
Academic Article	Cytokeratin 14 expression in rat liver cells in culture and localization in vivo.
Academic Article	Keratin gene expression in mouse epidermis and cultured epidermal cells.
Academic Article	Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13 but not keratins 1, 10, and 14.
Academic Article	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.
Academic Article	Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis.
Academic Article	A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis.
Academic Article	A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma.
Academic Article	Development of transgenic mouse models of skin carcinogenesis: potential applications.
Academic Article	Differentiation and tumor response to retinobenzoic acid RE-80 in a malignant conversion model.
Academic Article	Prenatal diagnosis for keratin mutations to exclude transmission of epidermolytic hyperkeratosis.
Academic Article	Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.
Academic Article	Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene.
Academic Article	Transgenic models of skin diseases.
Academic Article	Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Academic Article	A novel mutation in the 1A domain of keratin 2e in ichthyosis bullosa of Siemens.
Academic Article	A novel helix termination mutation in keratin 10 in annular epidermolytic ichthyosis, a variant of bullous congenital ichthyosiform erythroderma.
Academic Article	An asparagine to threonine substitution in the 1A domain of keratin 1: a novel mutation that causes epidermolytic hyperkeratosis.
Academic Article	Identification of a novel mutation in keratin 1 in a family with epidermolytic hyperkeratosis.
Academic Article	Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains.
Academic Article	Hot spot mutations in keratin 2e suggest a correlation between genotype and phenotype in patients with ichthyosis bullosa of Siemens.
Academic Article	Delayed wound healing in keratin 6a knockout mice.
Academic Article	Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders.
Academic Article	An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy.
Academic Article	K14-GLp65 transactivator induces transgene expression in embryonic epidermis.
Academic Article	Changes in photo-aged human skin following topical application of all-trans retinoic acid.
Academic Article	Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle.
Academic Article	Retinoids and control of epithelial differentiation and keratin biosynthesis in hamster trachea.
Academic Article	Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors.
Academic Article	Early expression of type I K13 keratin in the progression of mouse skin papillomas.
Academic Article	In utero activation of K5.CrePR1 induces gene deletion.
Academic Article	Interaction between dermal papilla and bulge: the rhino mouse mutation as a model system.
Academic Article	Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment.
Academic Article	The role of keratins in epidermal development and homeostasis--going beyond the obvious.
Academic Article	Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes.
Academic Article	A novel substitution in keratin 10 in epidermolytic hyperkeratosis.
Academic Article	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.
Academic Article	Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.
Academic Article	Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate.
Academic Article	The use of cDNA clones and monospecific antibodies as probes to monitor keratin gene expression.
Academic Article	Structural and functional implications of amino acid sequences of keratin intermediate filament subunits.
Academic Article	Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Academic Article	Vitamin A: a key nutrient for the maintenance of epithelial differentiation.
Academic Article	Regulation of keratin gene expression during differentiation of epidermal and vaginal epithelial cells.
Academic Article	The complete sequence of the human intermediate filament chain keratin 10. Subdomainal divisions and model for folding of end domain sequences.
Academic Article	A procedure for the culture of hair follicles as functionally intact organoids.
Academic Article	Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins.
Academic Article	Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
Academic Article	Signal transduction for proliferation and differentiation in keratinocytes.
Academic Article	Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis.
Academic Article	In situ hybridization analysis of keratin gene expression in human ameloblastomas.
Academic Article	Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis.
Academic Article	Structure of a gene for the human epidermal 67-kDa keratin.
Academic Article	Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits.
Academic Article	Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium.
Academic Article	A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes.
Academic Article	Myoepitheliomas in inbred laboratory mice.
Academic Article	Aurora kinase-A deficiency during skin development impairs cell division and stratification.
Academic Article	Prenatal diagnosis of epidermolytic hyperkeratosis by direct gene sequencing.
Academic Article	Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element.
Academic Article	Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations.
Academic Article	Retinoic acid suppression of loricrin expression in reconstituted human skin cultured at the liquid-air interface.
Academic Article	Expression of keratins in mouse vaginal epithelium.
Academic Article	Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution.
Academic Article	TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article	Hair follicle companion layer: reacquainting an old friend.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Academic Article	Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network.
Academic Article	Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
Academic Article	Inducible activation of oncogenic K-ras results in tumor formation in the oral cavity.
Academic Article	Altered distribution of keratinization markers in epidermolytic hyperkeratosis.
Academic Article	Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors.
Academic Article	Inducible mouse models for inherited skin diseases: implications for skin gene therapy.
Academic Article	Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Academic Article	Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: further evidence for a mutational hot spot.
Academic Article	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.
Academic Article	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.
Academic Article	Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders.
Academic Article	Keratin 6 is not essential for mammary gland development.
Academic Article	Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis.
Academic Article	An unexpected role for keratin 10 end domains in susceptibility to skin cancer.
Academic Article	Changes in keratin expression during 7,12-dimethylbenz[a]anthracene-induced hamster cheek pouch carcinogenesis.
Academic Article	The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes.
Academic Article	Epidermal morphogenesis and keratin expression in c-Ha-ras-transfected tumorigenic clones of the human HaCaT cell line.
Academic Article	Asymmetric cell division in skin development: a new look at an old observation.
Academic Article	Mouse models in preclinical studies for pachyonychia congenita.
Academic Article	Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas.
Academic Article	Aberrant differentiation in mouse skin carcinogenesis.
Academic Article	Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.
Academic Article	Genetically engineered mouse models for skin research: taking the next step.
Academic Article	The molecular biology of intermediate filaments.
Academic Article	Vitamin A deficiency and keratin biosynthesis in cultured hamster trachea.
Academic Article	An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue.
Academic Article	Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.
Academic Article	Abnormal expression and processing of keratins in pupoid fetus (pf/pf) and repeated epilation (Er/Er) mutant mice.
Academic Article	Keratin expression in mouse epidermal tumors.
Academic Article	Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones.
Academic Article	Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.
Academic Article	Aberrant expression during two-stage mouse skin carcinogenesis of a type I 47-kDa keratin, K13, normally associated with terminal differentiation of internal stratified epithelia.
Academic Article	Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research.
Concept	Keratins
Concept	Keratin-5
Concept	Keratin-14
Concept	Keratin-10
Concept	Keratin-2
Concept	Keratins, Type II
Concept	Keratins, Hair-Specific
Concept	Keratin-15
Concept	Keratin-6
Concept	Keratin-1
Academic Article	Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting.
Academic Article	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Academic Article	Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75.
Academic Article	Correction: A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Academic Article	Proteomic Analysis of Loricrin Knockout Mouse Epidermis.
Grant	REGULATION AND FUNCTION OF KERATINS IN THE EPIDERMIS
Grant	Regulation and Function of Keratins in the Epidermis
Grant	TARGETING HUMAN PAPILLOMA VIRUS GENE EXPRESSION IN MICE
Grant	Testing the Therapeutic Potential of iPS Cells for Inherited Skin Diseases
Grant	REGULATION AND FUNCTION OF A MAJOR CELL ENVELOPE PROTEIN

Search Criteria

Keratins