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Search Results to Dennis R Roop

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One or more keywords matched the following items that are connected to Roop, Dennis

Item TypeName
Academic Article Genetic disorders of keratin: are scarring alopecias a sub-set?
Academic Article Defects in the barrier.
Academic Article Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis.
Academic Article Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Academic Article Development of transgenic mouse models of skin carcinogenesis: potential applications.
Academic Article Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene.
Academic Article The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression.
Academic Article Characterization of loricrin regulation in vitro and in transgenic mice.
Academic Article Delayed wound healing in keratin 6a knockout mice.
Academic Article Deregulated expression of c-Myc depletes epidermal stem cells.
Academic Article Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors.
Academic Article The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation.
Academic Article Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Academic Article Transgenic mouse models provide new insights into the role of p63 in epidermal development.
Academic Article p63 is the molecular switch for initiation of an epithelial stratification program.
Academic Article Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes.
Academic Article Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.
Academic Article p63 induces key target genes required for epidermal morphogenesis.
Academic Article Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Academic Article Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.
Academic Article Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Academic Article A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.
Academic Article Signal transduction for proliferation and differentiation in keratinocytes.
Academic Article Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage.
Academic Article A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes.
Academic Article Aurora kinase-A deficiency during skin development impairs cell division and stratification.
Academic Article Generation of functional multipotent keratinocytes from mouse induced pluripotent stem cells.
Academic Article Genetic manipulation of keratinocyte stem cells with lentiviral vectors.
Academic Article The expression and modulation of IL-1 alpha in murine keratinocytes.
Academic Article Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures.
Academic Article Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations.
Academic Article TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network.
Academic Article Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
Academic Article IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis.
Academic Article Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.
Academic Article Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.
Academic Article Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Academic Article P63 deficiency: a failure of lineage commitment or stem cell maintenance?
Academic Article Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.
Academic Article Regulated cutaneous gene delivery: the skin as a bioreactor.
Academic Article An unexpected role for keratin 10 end domains in susceptibility to skin cancer.
Academic Article The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes.
Academic Article Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes.
Academic Article p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.
Academic Article IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias.
Academic Article Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones.
Academic Article Nrf2 links epidermal barrier function with antioxidant defense.
Academic Article Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.
Concept Keratinocytes
Academic Article Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
Academic Article Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.
Academic Article Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.
Academic Article Differentiation of human induced pluripotent stem cells into a keratinocyte lineage.
Academic Article MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Academic Article A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Academic Article Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Grant REGULATION AND FUNCTION OF KERATINS IN THE EPIDERMIS
Grant The consequences of loricrin deficiency on epidermal barrier function
Grant Regulation and Function of Keratins in the Epidermis
Grant Molecular Mechanisms of Skin and Appendage Development
Grant Testing the Therapeutic Potential of iPS Cells for Inherited Skin Diseases
Grant REGULATION AND FUNCTION OF A MAJOR CELL ENVELOPE PROTEIN
Grant Exploring Alternative iPS Cell Therapies for Recessive Dystrophic Epidermolysis Bullosa
Academic Article NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy.
Academic Article Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling.

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