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Search Results to Dennis R Roop

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Roop, Dennis

One or more keywords matched the following items that are connected to Roop, Dennis

Item Type	Name
Academic Article	Genetic disorders of keratin: are scarring alopecias a sub-set?
Academic Article	Defects in the barrier.
Academic Article	Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis.
Academic Article	Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Academic Article	Development of transgenic mouse models of skin carcinogenesis: potential applications.
Academic Article	Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene.
Academic Article	The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression.
Academic Article	Characterization of loricrin regulation in vitro and in transgenic mice.
Academic Article	Delayed wound healing in keratin 6a knockout mice.
Academic Article	Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors.
Academic Article	Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Academic Article	Transgenic mouse models provide new insights into the role of p63 in epidermal development.
Academic Article	p63 is the molecular switch for initiation of an epithelial stratification program.
Academic Article	Yin-yang 1 negatively regulates the differentiation-specific transcription of mouse loricrin gene in undifferentiated keratinocytes.
Academic Article	Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation.
Academic Article	p63 induces key target genes required for epidermal morphogenesis.
Academic Article	Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Academic Article	Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.
Academic Article	Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Academic Article	A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.
Academic Article	Signal transduction for proliferation and differentiation in keratinocytes.
Academic Article	Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage.
Academic Article	A human epidermal differentiation-specific keratin gene is regulated by calcium but not negative modulators of differentiation in transgenic mouse keratinocytes.
Academic Article	Aurora kinase-A deficiency during skin development impairs cell division and stratification.
Academic Article	Generation of functional multipotent keratinocytes from mouse induced pluripotent stem cells.
Academic Article	Genetic manipulation of keratinocyte stem cells with lentiviral vectors.
Academic Article	The expression and modulation of IL-1 alpha in murine keratinocytes.
Academic Article	Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures.
Academic Article	Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations.
Academic Article	TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article	Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network.
Academic Article	Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.
Academic Article	IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis.
Academic Article	Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.
Academic Article	Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.
Academic Article	Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Academic Article	P63 deficiency: a failure of lineage commitment or stem cell maintenance?
Academic Article	Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.
Academic Article	Regulated cutaneous gene delivery: the skin as a bioreactor.
Academic Article	An unexpected role for keratin 10 end domains in susceptibility to skin cancer.
Academic Article	The v-ras oncogene inhibits the expression of differentiation markers and facilitates expression of cytokeratins 8 and 18 in mouse keratinocytes.
Academic Article	Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes.
Academic Article	p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.
Academic Article	IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias.
Academic Article	Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones.
Academic Article	Nrf2 links epidermal barrier function with antioxidant defense.
Academic Article	Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.
Concept	Keratinocytes
Academic Article	Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
Academic Article	Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.
Academic Article	Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.
Academic Article	Differentiation of human induced pluripotent stem cells into a keratinocyte lineage.
Academic Article	MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.
Academic Article	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Academic Article	Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Grant	REGULATION AND FUNCTION OF KERATINS IN THE EPIDERMIS
Grant	The consequences of loricrin deficiency on epidermal barrier function
Grant	Regulation and Function of Keratins in the Epidermis
Grant	Molecular Mechanisms of Skin and Appendage Development
Grant	Testing the Therapeutic Potential of iPS Cells for Inherited Skin Diseases
Grant	REGULATION AND FUNCTION OF A MAJOR CELL ENVELOPE PROTEIN
Grant	Exploring Alternative iPS Cell Therapies for Recessive Dystrophic Epidermolysis Bullosa
Academic Article	NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy.
Academic Article	Melanocyte Precursors in the Hair Follicle Bulge of Repigmented Vitiligo Skin Are Controlled by RHO-GTPase, KCTD10, and CTNNB1 Signaling.
Academic Article	Loricrin Protects against Chemical Carcinogenesis.
Academic Article	Loricrin at the Boundary between Inside and Outside.

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Keratinocytes