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Search Results to Dennis R Roop

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Roop, Dennis

One or more keywords matched the following items that are connected to Roop, Dennis

Item Type	Name
Academic Article	Expression of keratin genes in mouse epidermis and normal and malignantly transformed epidermal cells in culture.
Academic Article	Structural features of epidermal keratin filaments reassembled in vitro.
Academic Article	Genetic disorders of keratin: are scarring alopecias a sub-set?
Academic Article	Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.
Academic Article	Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.
Academic Article	Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion.
Academic Article	Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development.
Academic Article	Epidermis: an attractive target tissue for gene therapy.
Academic Article	Loricrin immunoreactivity in human skin: localization to specific granules (L-granules) in acrosyringia.
Academic Article	Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis.
Academic Article	Keratin gene expression in mouse epidermis and cultured epidermal cells.
Academic Article	Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Academic Article	A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis.
Academic Article	A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice.
Academic Article	Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.
Academic Article	Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene.
Academic Article	Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Academic Article	Full-thickness skin grafts from flaky skin mice to nude mice: maintenance of the psoriasiform phenotype.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Academic Article	Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains.
Academic Article	Delayed wound healing in keratin 6a knockout mice.
Academic Article	K14-GLp65 transactivator induces transgene expression in embryonic epidermis.
Academic Article	Quasi-normal cornified cell envelopes in loricrin knockout mice imply the existence of a loricrin backup system.
Academic Article	In utero activation of K5.CrePR1 induces gene deletion.
Academic Article	Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.
Academic Article	Transgenic mouse models provide new insights into the role of p63 in epidermal development.
Academic Article	The role of keratins in epidermal development and homeostasis--going beyond the obvious.
Academic Article	Genetic pathways required for epidermal morphogenesis.
Academic Article	p63 and epithelial appendage development.
Academic Article	Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.
Academic Article	p63 is a p53 homologue required for limb and epidermal morphogenesis.
Academic Article	The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4.
Academic Article	p63 induces key target genes required for epidermal morphogenesis.
Academic Article	Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function.
Academic Article	Mechanisms regulating epithelial stratification.
Academic Article	Cooperation of Ha-ras and Bcl-2 during multistep skin carcinogenesis.
Academic Article	Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice.
Academic Article	Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins.
Academic Article	Signal transduction for proliferation and differentiation in keratinocytes.
Academic Article	Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis.
Academic Article	Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis.
Academic Article	Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.
Academic Article	Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage.
Academic Article	Structure of a gene for the human epidermal 67-kDa keratin.
Academic Article	Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein.
Academic Article	The expression and modulation of IL-1 alpha in murine keratinocytes.
Academic Article	Regulated synthesis of low-molecular-weight antigens in keratinocyte cell cultures.
Academic Article	Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution.
Academic Article	TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas.
Academic Article	12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mice expressing epidermal-targeted v-fos induces rasHA-activated papillomas and carcinomas without p53 mutation: association of v-fos expression with promotion and tumor autonomy.
Academic Article	Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network.
Academic Article	IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis.
Academic Article	Development of transgenic mice that inducibly express an active form of c-Src in the epidermis.
Academic Article	Inducible mouse models for inherited skin diseases: implications for skin gene therapy.
Academic Article	Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition.
Academic Article	Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function.
Academic Article	P63 deficiency: a failure of lineage commitment or stem cell maintenance?
Academic Article	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.
Academic Article	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.
Academic Article	Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.
Academic Article	Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders.
Academic Article	Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis.
Academic Article	Regulated cutaneous gene delivery: the skin as a bioreactor.
Academic Article	Conflicting roles for p63 in skin development and carcinogenesis.
Academic Article	The role of p63 in development and differentiation of the epidermis.
Academic Article	Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease.
Academic Article	Double-inducible gene activation system for caspase 3 and 9 in epidermis.
Academic Article	Asymmetric cell division in skin development: a new look at an old observation.
Academic Article	TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis.
Academic Article	Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes.
Academic Article	p63 directly induces expression of Alox12, a regulator of epidermal barrier formation.
Academic Article	Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro.
Academic Article	An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue.
Academic Article	A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis.
Academic Article	Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.
Concept	Epidermis
Academic Article	Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
Academic Article	Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.
Academic Article	Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype.
Academic Article	Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors.
Academic Article	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.
Academic Article	Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for?the Loss of Loricrin.
Academic Article	Proteomic Analysis of Loricrin Knockout Mouse Epidermis.
Academic Article	Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Academic Article	Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease.
Grant	REGULATION AND FUNCTION OF KERATINS IN THE EPIDERMIS
Grant	The consequences of loricrin deficiency on epidermal barrier function
Grant	Regulation and Function of Keratins in the Epidermis
Grant	TARGETING HUMAN PAPILLOMA VIRUS GENE EXPRESSION IN MICE
Grant	Molecular Mechanisms of Skin and Appendage Development
Grant	Testing the Therapeutic Potential of iPS Cells for Inherited Skin Diseases
Grant	REGULATION AND FUNCTION OF A MAJOR CELL ENVELOPE PROTEIN
Academic Article	Loricrin Confers Photoprotective Function against?UVB in Corneocytes.
Academic Article	Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging.
Academic Article	Loricrin: Past, Present, and Future.
Academic Article	NRF2 Augments Epidermal Antioxidant Defenses and Promotes Atopy.
Academic Article	The Epidermis: Redox Governor of Health and Diseases.
Academic Article	Loricrin at the Boundary between Inside and Outside.

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