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Search Results to Charles A Dinarello

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One or more keywords matched the following items that are connected to Dinarello, Charles

Item TypeName
Academic Article Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells.
Academic Article Cytokines in acute myocardial infarction: selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist.
Academic Article Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice.
Academic Article Blocking interleukin-1 receptors.
Academic Article Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro.
Academic Article Ciliary neurotrophic factor is an endogenous pyrogen.
Academic Article Induction of circulating IL-1 receptor antagonist by IFN treatment.
Academic Article Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1.
Academic Article Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels.
Academic Article Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors.
Academic Article Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy.
Academic Article Granulocyte-macrophage colony-stimulating factor synthesis during experimental endotoxemia in humans.
Academic Article Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells.
Academic Article Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.
Academic Article To Sheldon M. Wolff, as we commemorate the 10th anniversary of the clonings of IL-1 alpha and IL-1 beta.
Academic Article The biological properties of interleukin-1.
Academic Article Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article Interleukin 18 stimulates HIV type 1 in monocytic cells.
Academic Article Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event.
Academic Article Effect of interleukin-18 on mouse core body temperature.
Academic Article Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice.
Academic Article IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
Academic Article Rat interleukin-18 binding protein: cloning, expression, and characterization.
Academic Article Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
Academic Article A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity.
Academic Article A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits.
Academic Article Peripheral nerve regeneration is impeded by interleukin-1 receptor antagonist released from a polymeric guidance channel.
Academic Article Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells.
Academic Article Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro.
Academic Article Biology of tumor necrosis factor-alpha- implications for psoriasis.
Academic Article Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
Academic Article Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
Academic Article Interleukin-18 does not modulate the acute-phase response.
Academic Article Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells.
Academic Article TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction.
Academic Article Interleukin-1, anorexia, and dietary fatty acids.
Academic Article Sustained delivery of IL-1 Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases.
Academic Article Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells.
Academic Article Proteinase 3-processed form of the recombinant IL-32 separate domain.
Academic Article Identification of the most active interleukin-32 isoform.
Academic Article Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats.
Academic Article Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis.
Academic Article Regulation of eicosanoid production in rabbit colon by interleukin-1.
Academic Article Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis.
Academic Article Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen.
Academic Article Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.
Academic Article The stimulation of collagenase production in rabbit articular chondrocytes by interleukin-1 is increased by collagens.
Academic Article Lymphokines and bile secretion in the rat.
Academic Article Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils.
Academic Article Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin).
Academic Article Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.
Academic Article Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF.
Academic Article Occurrence of interleukin-1 in cerebrospinal fluid of the conscious cat.
Academic Article Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1.
Academic Article Recombinant interleukin 1 and tumor necrosis factor acting in synergy to release thromboxane, 6-KETO-PGF1 alpha and PGE2 by human neutrophils.
Academic Article Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.
Academic Article Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans.
Academic Article Interleukin-1.
Academic Article Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.
Academic Article Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.
Academic Article Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients.
Academic Article Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.
Academic Article The multiple biological properties of interleukin-1 influencing immunocompetent cells.
Academic Article Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells.
Academic Article In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1.
Academic Article Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia.
Academic Article Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep.
Academic Article Development and use of a radioimmunoassay for human interleukin-1 beta.
Academic Article Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor.
Academic Article Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated.
Academic Article Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism.
Academic Article Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats.
Academic Article Soluble tumor necrosis factor receptors inhibit phorbol myristate acetate and cytokine-induced HIV-1 expression chronically infected U1 cells.
Academic Article Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1.
Academic Article Induction of interleukin-1 and interleukin-1 receptor antagonist.
Academic Article Monocyte cytokine production in an elderly population: effect of age and inflammation.
Academic Article Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.
Academic Article Phase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera.
Academic Article Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Academic Article Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells.
Academic Article Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.
Academic Article Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Academic Article IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
Academic Article Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium.
Academic Article IL-1 is required for tumor invasiveness and angiogenesis.
Academic Article Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
Academic Article Differences in signaling pathways by IL-1beta and IL-18.
Academic Article Interleukin-32: a cytokine and inducer of TNFalpha.
Academic Article Interleukin-1beta.
Academic Article Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha.
Academic Article Functional and morphological effects of interleukin-1 beta on the perfused rat pancreas.
Academic Article Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
Academic Article Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself.
Academic Article Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.
Academic Article Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA.
Academic Article Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins.
Academic Article Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors.
Academic Article Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain.
Academic Article Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
Academic Article Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings.
Academic Article Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens.
Academic Article Studies on IL-1 receptors on D10S T-helper cells: demonstration of two molecularly and antigenically distinct IL-1 binding proteins.
Academic Article Differential effects of interleukin-1 alpha and interleukin-1 beta on human peripheral blood eosinophils.
Academic Article Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism.
Academic Article Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes.
Academic Article Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
Academic Article Studies on the biological properties of purified and recombinant human interleukin-1.
Academic Article Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing?
Academic Article Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium.
Academic Article Increased interleukin 1 beta in human skeletal muscle after exercise.
Academic Article Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.
Academic Article Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis.
Academic Article A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia.
Academic Article Interleukin-1 and glucocorticoid hormones integrate an immunoregulatory feedback circuit.
Academic Article Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.
Academic Article A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection.
Academic Article Interleukin-1 induces natriuresis in conscious rats: role of renal prostaglandins.
Academic Article Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits.
Academic Article Recombinant human interleukin-1 beta causes histamine release from human basophils.
Academic Article Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels.
Academic Article Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.
Academic Article Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.
Academic Article Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.
Academic Article Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.
Academic Article Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells.
Academic Article Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line.
Academic Article Direct stimulation of the adrenal cortex by interleukin-1.
Academic Article Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1.
Academic Article Multiple biological activities of human recombinant interleukin 1.
Concept Recombinant Proteins
Academic Article Anti-inflammatory and immunomodulatory properties of a1-antitrypsin without inhibition of elastase.
Academic Article Clone controversy at Immunex.
Academic Article Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.
Academic Article Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
Academic Article Treating pulmonary silicosis by blocking interleukin 1.
Academic Article IL-1a is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.
Academic Article Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.
Academic Article Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.
Academic Article Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice.
Academic Article Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.
Academic Article IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells.
Academic Article Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue.
Academic Article Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.
Academic Article Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation.

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