Item Type | Name |
Academic Article
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Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1).
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Academic Article
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Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells.
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Academic Article
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The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen.
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Academic Article
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Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat.
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Academic Article
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Molecular mechanisms in endotoxin fever.
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Academic Article
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Fibroblast stimulation in schistosomiasis. V. Egg granuloma macrophages spontaneously secrete a fibroblast-stimulating factor.
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Academic Article
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Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma.
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Academic Article
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Production of fever and its effects on the host.
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Academic Article
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Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans.
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Academic Article
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Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation.
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Academic Article
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Molecular basis of fever in humans.
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Academic Article
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Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism.
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Academic Article
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Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells.
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Academic Article
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Cytokines in acute myocardial infarction: selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist.
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Academic Article
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Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes--evidence for polygenicity in man. Danish Study Group of Diabetes in Childhood.
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Academic Article
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Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells.
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Academic Article
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Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice.
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Academic Article
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Blocking interleukin-1 receptors.
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Academic Article
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Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro.
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Academic Article
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The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.
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Academic Article
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Ciliary neurotrophic factor is an endogenous pyrogen.
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Academic Article
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Induction of circulating and erythrocyte-bound IL-8 by IL-2 immunotherapy and suppression of its in vitro production by IL-1 receptor antagonist and soluble tumor necrosis factor receptor (p75) chimera.
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Academic Article
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Induction of circulating IL-1 receptor antagonist by IFN treatment.
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Academic Article
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Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1.
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Academic Article
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Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels.
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Academic Article
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Role of interleukin 1 in antigen-specific T cell proliferation.
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Academic Article
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Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors.
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Academic Article
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Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy.
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Academic Article
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Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis.
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Academic Article
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Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.
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Academic Article
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Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever.
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Academic Article
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[Demonstration of a bacterial structure in two human mediators: a sleep facilitating factor and a monokine].
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Academic Article
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Granulocyte-macrophage colony-stimulating factor synthesis during experimental endotoxemia in humans.
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Academic Article
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Mechanisms of loss of lean body mass in patients on chronic dialysis.
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Academic Article
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IL-6 and APPs: anti-inflammatory and immunosuppressive mediators.
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Academic Article
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Studies on the active site of human leukocytic pyrogen.
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Academic Article
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Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro.
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Academic Article
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Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells.
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Academic Article
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Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.
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Academic Article
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[Antagonists in neonatal sepsis].
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Academic Article
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Recent advances in cytokines, cytokine receptors and signal transduction.
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Academic Article
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To Sheldon M. Wolff, as we commemorate the 10th anniversary of the clonings of IL-1 alpha and IL-1 beta.
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Academic Article
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The biological properties of interleukin-1.
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Academic Article
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Leptin deficiency enhances sensitivity to endotoxin-induced lethality.
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Academic Article
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Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
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Academic Article
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Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes.
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Academic Article
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Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes.
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Academic Article
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Interleukin 18 stimulates HIV type 1 in monocytic cells.
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Academic Article
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Circulating leptin during experimental endotoxemia in humans.
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Academic Article
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Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.
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Academic Article
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Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.
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Academic Article
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IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.
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Academic Article
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Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event.
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Academic Article
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The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense.
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Academic Article
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Biologic basis for interleukin-1 in disease.
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Academic Article
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Protein metabolism in rheumatoid arthritis and aging. Effects of muscle strength training and tumor necrosis factor alpha.
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Academic Article
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Role of interferon regulatory factor-1 in the regulation of IL-18 production and activity.
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Academic Article
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Tumor necrosis factor (TNF)-alpha-induced interleukin-8 in human blood cultures discriminates neutralization by the p55 and p75 TNF soluble receptors.
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Academic Article
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Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells.
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Academic Article
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Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist.
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Academic Article
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Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18.
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Academic Article
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Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma.
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Academic Article
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Identification of amino acid residues critical for biological activity in human interleukin-18.
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Academic Article
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Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1.
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Academic Article
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Novel targets for interleukin 18 binding protein.
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Academic Article
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Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice.
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Academic Article
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IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
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Academic Article
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Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants.
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Academic Article
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Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.
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Academic Article
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Rat interleukin-18 binding protein: cloning, expression, and characterization.
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Academic Article
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Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1 beta activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein.
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Academic Article
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Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
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Academic Article
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A surface amebic cysteine proteinase inactivates interleukin-18.
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Academic Article
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A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits.
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Academic Article
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Peripheral nerve regeneration is impeded by interleukin-1 receptor antagonist released from a polymeric guidance channel.
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Academic Article
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Enhancement of growth of virulent strains of Escherichia coli by interleukin-1.
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Academic Article
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Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells.
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Academic Article
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Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein.
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Academic Article
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Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex.
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Academic Article
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Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease.
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Academic Article
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The IL-1 family and inflammatory diseases.
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Academic Article
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Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro.
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Academic Article
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Biology of tumor necrosis factor-alpha- implications for psoriasis.
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Academic Article
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Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
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Academic Article
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Mutation scan of a type 1 diabetes candidate gene: the human interleukin-18 binding protein gene.
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Academic Article
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Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release.
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Academic Article
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Interleukin-1 is a mucus secretagogue.
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Academic Article
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Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein.
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Academic Article
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Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed.
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Academic Article
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Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
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Academic Article
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Interleukin-18 does not modulate the acute-phase response.
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Academic Article
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Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF-alpha, IFN-gamma and glucocorticoids.
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Academic Article
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IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response.
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Academic Article
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Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells.
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Academic Article
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TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction.
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Academic Article
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Interleukin-1, anorexia, and dietary fatty acids.
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Academic Article
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Sustained delivery of IL-1 Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases.
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Academic Article
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Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis.
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Academic Article
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Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice.
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Academic Article
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The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
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Academic Article
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Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells.
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Academic Article
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Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury.
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Academic Article
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Dissociation between interleukin-1 beta mRNA and protein synthesis in human peripheral blood mononuclear cells.
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Academic Article
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Proteinase 3-processed form of the recombinant IL-32 separate domain.
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Academic Article
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Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury.
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Academic Article
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Identification of the most active interleukin-32 isoform.
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Academic Article
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IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
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Academic Article
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Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.
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Academic Article
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Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats.
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Academic Article
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Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro.
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Academic Article
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Interleukin-1: multiple biological properties and mechanisms of action.
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Academic Article
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IL-18 activity in systemic lupus erythematosus.
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Academic Article
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Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils.
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Academic Article
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Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.
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Academic Article
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Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta.
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Academic Article
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Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis.
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Academic Article
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Synthetic peptide corresponding to a conserved domain of the retroviral protein p15E blocks IL-1-mediated signal transduction.
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Academic Article
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Serum and urinary levels of IL-18 and its inhibitor IL-18BP in systemic lupus erythematosus.
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Academic Article
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Regulation of eicosanoid production in rabbit colon by interleukin-1.
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Academic Article
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Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta.
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Academic Article
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Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.
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Academic Article
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Production of interleukin-1-receptor antagonist during experimental endotoxaemia.
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Academic Article
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?2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo.
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Academic Article
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Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis.
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Academic Article
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IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
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Academic Article
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IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.
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Academic Article
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Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen.
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Academic Article
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Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.
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Academic Article
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The stimulation of collagenase production in rabbit articular chondrocytes by interleukin-1 is increased by collagens.
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Academic Article
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Role of IL-18 in second-hand smoke-induced emphysema.
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Academic Article
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IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor.
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Academic Article
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Lymphokines and bile secretion in the rat.
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Academic Article
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Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils.
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Academic Article
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Effect of protein depletion and short-term parenteral refeeding on the host response to interleukin 1 administration.
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Academic Article
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Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin).
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Academic Article
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Chemical characterization of an interleukin-1-inducing substance derived from human mixed leukocyte reactions: IL-1-inducing substance is not gamma interferon.
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Academic Article
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Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.
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Academic Article
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Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF.
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Academic Article
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Occurrence of interleukin-1 in cerebrospinal fluid of the conscious cat.
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Academic Article
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Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1.
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Academic Article
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Recombinant interleukin 1 and tumor necrosis factor acting in synergy to release thromboxane, 6-KETO-PGF1 alpha and PGE2 by human neutrophils.
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Academic Article
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Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.
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Academic Article
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Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans.
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Academic Article
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Interleukin-1.
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Academic Article
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Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.
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Academic Article
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Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.
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Academic Article
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Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients.
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Academic Article
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Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.
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Academic Article
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The multiple biological properties of interleukin-1 influencing immunocompetent cells.
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Academic Article
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Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production.
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Academic Article
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Purification and characterization of a unique human interleukin 1 from the tumor cell line U937.
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Academic Article
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Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells.
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Academic Article
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In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1.
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Academic Article
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Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia.
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Academic Article
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Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep.
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Academic Article
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Development and use of a radioimmunoassay for human interleukin-1 beta.
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Academic Article
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Acute inflammation in gram-negative infection: endotoxin, interleukin 1, tumor necrosis factor, and neutrophils.
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Academic Article
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Interleukin-1 and the pathogenesis of the acute-phase response.
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Academic Article
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Interleukin-1.
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Academic Article
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Interleukin 1 as mediator of the acute-phase response.
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Academic Article
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Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.
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Academic Article
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The biology of SAA: identification of the inducer, in vitro synthesis, and heterogeneity demonstrated with monoclonal antibodies.
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Academic Article
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Reduced mitogen stimulation of DNA synthesis in human lymphocytes by a human recombinant interleukin-1 receptor antagonist.
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Academic Article
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Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor.
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Academic Article
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Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated.
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Academic Article
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Production of leukocytic pyrogen from phagocytes of neonates.
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Academic Article
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Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure.
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Academic Article
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Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism.
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Academic Article
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The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription.
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Academic Article
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Production of cytokines and cytokine inhibitory proteins in patients on dialysis.
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Academic Article
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Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats.
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Academic Article
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Identification of the promoter region of human interleukin 1 type I receptor gene: multiple initiation sites, high G+C content, and constitutive expression.
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Academic Article
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Soluble tumor necrosis factor receptors inhibit phorbol myristate acetate and cytokine-induced HIV-1 expression chronically infected U1 cells.
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Academic Article
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Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1.
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Academic Article
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Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis.
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Academic Article
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Induction of interleukin-1 and interleukin-1 receptor antagonist.
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Academic Article
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Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin.
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Academic Article
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Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
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Academic Article
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Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome.
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Academic Article
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Monocyte cytokine production in an elderly population: effect of age and inflammation.
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Academic Article
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Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.
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Academic Article
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Phase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera.
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Academic Article
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Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
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Academic Article
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Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells.
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Academic Article
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Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.
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Academic Article
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Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.
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Academic Article
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Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
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Academic Article
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IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
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Academic Article
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Targeting interleukin 18 with interleukin 18 binding protein.
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Academic Article
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An IFN-gamma-independent proinflammatory role of IL-18 in murine streptococcal cell wall arthritis.
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Academic Article
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Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia.
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Academic Article
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IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
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Academic Article
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Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
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Academic Article
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Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium.
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Academic Article
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IL-1 is required for tumor invasiveness and angiogenesis.
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Academic Article
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Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure.
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Academic Article
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Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity?
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Academic Article
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Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
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Academic Article
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Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
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Academic Article
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Unraveling the NALP-3/IL-1beta inflammasome: a big lesson from a small mutation.
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Academic Article
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Differences in signaling pathways by IL-1beta and IL-18.
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Academic Article
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Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease.
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Academic Article
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Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha.
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Academic Article
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Interleukin-32: a cytokine and inducer of TNFalpha.
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Academic Article
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Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease.
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Academic Article
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Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.
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Academic Article
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IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
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Academic Article
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Interleukin-1beta.
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Academic Article
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Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha.
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Academic Article
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Transcription, not synthesis, of interleukin-1 and tumor necrosis factor by complement.
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Academic Article
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Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor.
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Academic Article
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Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
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Academic Article
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Functional and morphological effects of interleukin-1 beta on the perfused rat pancreas.
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Academic Article
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High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein.
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Academic Article
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Interleukin-18 and the pathogenesis of inflammatory diseases.
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Academic Article
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IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.
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Academic Article
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Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
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Academic Article
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Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself.
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Academic Article
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Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity.
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Academic Article
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Leukocyte endogenous mediator fails to alter protein dynamics in a model of liver dysfunction.
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Academic Article
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Interleukin-1 and its biologically related cytokines.
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Academic Article
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Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.
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Academic Article
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Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA.
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Academic Article
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Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins.
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Academic Article
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Interleukin-18 binding protein in the sera of patients with Wegener's granulomatosis.
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Academic Article
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Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors.
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Academic Article
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Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain.
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Academic Article
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Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.
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Academic Article
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Immunological and inflammatory functions of the interleukin-1 family.
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Academic Article
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Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.
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Academic Article
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Interleukin-1beta and the autoinflammatory diseases.
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Academic Article
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Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
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Academic Article
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Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells.
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Academic Article
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The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis.
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Academic Article
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Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings.
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Academic Article
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Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation.
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Academic Article
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The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.
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Academic Article
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The interleukin 1 receptor.
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Academic Article
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Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens.
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Academic Article
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Studies on IL-1 receptors on D10S T-helper cells: demonstration of two molecularly and antigenically distinct IL-1 binding proteins.
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Academic Article
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Differential effects of interleukin-1 alpha and interleukin-1 beta on human peripheral blood eosinophils.
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Academic Article
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The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering.
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Academic Article
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The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1?.
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Academic Article
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Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1.
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Academic Article
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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases.
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Academic Article
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NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1? processing via the NLRP1 inflammasome.
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Academic Article
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Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism.
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Academic Article
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Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes.
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Academic Article
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Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
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Academic Article
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Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling.
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Academic Article
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Studies on the biological properties of purified and recombinant human interleukin-1.
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Academic Article
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Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing?
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Academic Article
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Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium.
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Academic Article
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Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol.
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Academic Article
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Increased interleukin 1 beta in human skeletal muscle after exercise.
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Academic Article
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Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.
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Academic Article
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Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis.
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Academic Article
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A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia.
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Academic Article
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Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.
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Academic Article
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Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.
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Academic Article
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Effect of recombinant a1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes.
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Academic Article
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Interleukin-1 and glucocorticoid hormones integrate an immunoregulatory feedback circuit.
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Academic Article
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Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.
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Academic Article
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A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection.
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Academic Article
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Interleukin-1 induces natriuresis in conscious rats: role of renal prostaglandins.
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Academic Article
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Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits.
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Academic Article
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Recombinant human interleukin-1 beta causes histamine release from human basophils.
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Academic Article
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Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels.
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Academic Article
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Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.
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Academic Article
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Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.
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Academic Article
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Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.
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Academic Article
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Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.
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Academic Article
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Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells.
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Academic Article
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Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line.
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Academic Article
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Direct stimulation of the adrenal cortex by interleukin-1.
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Academic Article
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Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1.
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Academic Article
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Multiple biological activities of human recombinant interleukin 1.
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Academic Article
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Intracellular human IL-1: a precursor for the secreted monokine.
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Concept
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Suppressor of Cytokine Signaling Proteins
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Concept
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Oncogene Proteins, Viral
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Concept
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Cytoskeletal Proteins
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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Proto-Oncogene Proteins c-fyn
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Concept
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Membrane Proteins
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Concept
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Soybean Proteins
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Concept
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DNA-Binding Proteins
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Concept
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Muscle Proteins
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Concept
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Fatty Acid-Binding Proteins
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Concept
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HSP70 Heat-Shock Proteins
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Concept
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Macrophage Inflammatory Proteins
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Concept
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Papillomavirus E7 Proteins
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Concept
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Green Fluorescent Proteins
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Concept
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Bacterial Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Calcium-Binding Proteins
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Concept
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Saccharomyces cerevisiae Proteins
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Concept
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Proto-Oncogene Proteins B-raf
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Concept
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Helminth Proteins
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Concept
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Carrier Proteins
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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Immobilized Proteins
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Concept
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Recombinant Proteins
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Concept
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Neoplasm Proteins
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Concept
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Drosophila Proteins
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Concept
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CCAAT-Enhancer-Binding Proteins
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Concept
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I-kappa B Proteins
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Concept
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Fusion Proteins, bcr-abl
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Concept
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Acute-Phase Proteins
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Concept
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Extracellular Matrix Proteins
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Apoptosis Regulatory Proteins
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Concept
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Proto-Oncogene Proteins
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Concept
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Blood Proteins
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Concept
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Protozoan Proteins
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Concept
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Nerve Tissue Proteins
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Concept
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RNA-Binding Proteins
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Concept
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Viral Proteins
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Repressor Proteins
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Concept
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Angiogenic Proteins
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Concept
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Complement System Proteins
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Concept
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Bone Morphogenetic Proteins
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Concept
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Retroviridae Proteins
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proteins
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Concept
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Microtubule-Associated Proteins
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Concept
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CARD Signaling Adaptor Proteins
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Academic Article
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Anti-inflammatory and immunomodulatory properties of a1-antitrypsin without inhibition of elastase.
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Academic Article
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The C3a receptor, caspase-1, and release of IL-1?.
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Academic Article
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Treating inflammation by blocking interleukin-1 in humans.
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Academic Article
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Interleukin-1? in innate inflammation, autophagy and immunity.
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Academic Article
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Interleukin-18, more than a Th1 cytokine.
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Academic Article
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Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.
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Academic Article
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IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.
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Academic Article
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Acute-phase protein a1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion.
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Academic Article
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IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis.
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Academic Article
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Clone controversy at Immunex.
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Academic Article
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Comparison of chemical analyses of hollow-fiber dialyzer extracts.
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Academic Article
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Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.
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Academic Article
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Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
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Academic Article
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An anti-inflammatory property of Candida albicans ?-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
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Academic Article
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Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
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Academic Article
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Treating pulmonary silicosis by blocking interleukin 1.
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Academic Article
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Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance.
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Academic Article
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IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.
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Academic Article
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Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels.
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Academic Article
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IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.
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Academic Article
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Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra.
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Academic Article
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a1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression.
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Academic Article
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IL-1a is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.
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Academic Article
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Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
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Academic Article
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Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies.
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Academic Article
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IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
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Academic Article
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Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1? and by the induction of endogenous IL-1Ra.
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Academic Article
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Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition.
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Academic Article
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Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.
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Academic Article
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Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.
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Academic Article
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IL-1 Inhibition and Vascular Function in CKD.
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Academic Article
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Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice.
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Academic Article
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Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.
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Academic Article
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NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma.
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Academic Article
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IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells.
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Academic Article
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Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.
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Academic Article
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IL-18 binding protein reverses the life-threatening hyperinflammation of a baby with the NLRC4 mutation.
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Academic Article
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Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue.
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Concept
|
NLR Proteins
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Concept
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Autophagy-Related Proteins
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Concept
|
Angiopoietin-like Proteins
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Concept
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Pancreatitis-Associated Proteins
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Concept
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Matrilin Proteins
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Academic Article
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Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.
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Academic Article
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Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.
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Academic Article
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Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
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Academic Article
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Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation.
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Academic Article
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Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.
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Academic Article
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Urate-induced epigenetic modifications in myeloid cells.
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Academic Article
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Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery-on-a-chip.
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Academic Article
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Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions.
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Academic Article
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Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3.
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Academic Article
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Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions.
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Academic Article
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IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1? secretion.
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