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Search Results to Charles A Dinarello

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Dinarello, Charles

One or more keywords matched the following items that are connected to Dinarello, Charles

Item Type	Name
Academic Article	The role of the liver in the production of fever and in pyrogenic tolerance.
Academic Article	The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen.
Academic Article	Fibroblast stimulation in schistosomiasis. V. Egg granuloma macrophages spontaneously secrete a fibroblast-stimulating factor.
Academic Article	Sleep-promoting effects of endogenous pyrogen (interleukin-1).
Academic Article	Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism.
Academic Article	Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10.
Academic Article	Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells.
Academic Article	Effect of endotoxin in IL-1 beta-deficient mice.
Academic Article	Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy.
Academic Article	[Demonstration of a bacterial structure in two human mediators: a sleep facilitating factor and a monokine].
Academic Article	Granulocyte-macrophage colony-stimulating factor synthesis during experimental endotoxemia in humans.
Academic Article	Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays.
Academic Article	Leptin deficiency enhances sensitivity to endotoxin-induced lethality.
Academic Article	Soluble murine IL-1 receptor type I induces release of constitutive IL-1 alpha.
Academic Article	Interleukin-18.
Academic Article	Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).
Academic Article	Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55.
Academic Article	IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.
Academic Article	Modulation of cell proliferation and cytokine production in AML by recombinant interleukin-1 receptor antagonist.
Academic Article	Osmotic regulation of cytokine synthesis in vitro.
Academic Article	Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1.
Academic Article	Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.
Academic Article	Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
Academic Article	GM-CSF DNA induces specific patterns of cytokines and chemokines in the skin: implications for DNA vaccines.
Academic Article	Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells.
Academic Article	Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein.
Academic Article	Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.
Academic Article	Interleukin-1 is a mucus secretagogue.
Academic Article	Melanoma inhibits macrophage activation by suppressing toll-like receptor 4 signaling.
Academic Article	IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Academic Article	Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article	The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity.
Academic Article	TNF-alpha neutralization ameliorates obstruction-induced renal fibrosis and dysfunction.
Academic Article	Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1).
Academic Article	The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
Academic Article	Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury.
Academic Article	Identification of the most active interleukin-32 isoform.
Academic Article	IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
Academic Article	Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.
Academic Article	Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta.
Academic Article	IL-1 production by T6 (CD1a) positive cord blood mononuclear cells (Langerhan's cell precursors?).
Academic Article	Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta.
Academic Article	The endogenous pyrogens in host-defense interactions.
Academic Article	The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ? cells in vivo and in vitro.
Academic Article	Defective localization of the NADPH phagocyte oxidase to Salmonella-containing phagosomes in tumor necrosis factor p55 receptor-deficient macrophages.
Academic Article	IL-1a and IL-1? recruit different myeloid cells and promote different stages of sterile inflammation.
Academic Article	IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.
Academic Article	The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
Academic Article	The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses.
Academic Article	A peptide from alveolar macrophages that releases neutrophil enzymes into the lungs in patients with the adult respiratory distress syndrome.
Academic Article	Role of IL-18 in second-hand smoke-induced emphysema.
Academic Article	Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type.
Academic Article	Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1.
Academic Article	Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.
Academic Article	In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1.
Academic Article	Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.
Academic Article	Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated.
Academic Article	Clinical, hematologic, and immunologic effects of interleukin-10 in humans.
Academic Article	Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis.
Academic Article	Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
Academic Article	Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome.
Academic Article	IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
Academic Article	Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Academic Article	IL-1 is required for tumor invasiveness and angiogenesis.
Academic Article	Differences in signaling pathways by IL-1beta and IL-18.
Academic Article	Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.
Academic Article	Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha.
Academic Article	Interleukin-32 induces the differentiation of monocytes into macrophage-like cells.
Academic Article	Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Academic Article	IL-18 in autoimmunity: review.
Academic Article	Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
Academic Article	Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1a, IL-1? or IL-1 receptor type I.
Academic Article	Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.
Academic Article	The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis.
Academic Article	Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta.
Academic Article	IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages.
Academic Article	A clinical perspective of IL-1? as the gatekeeper of inflammation.
Academic Article	The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering.
Academic Article	Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
Academic Article	Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity.
Academic Article	Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing?
Academic Article	Role of interleukin-1 in the depression of liver drug metabolism by endotoxin.
Academic Article	Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide.
Academic Article	Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol.
Academic Article	Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps.
Academic Article	Innate immune response of human alveolar macrophages during influenza A infection.
Academic Article	Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain.
Academic Article	Interleukin-1 and dialysis.
Academic Article	Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.
Academic Article	Induction of interleukin-1 during CAPD.
Academic Article	Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.
Academic Article	Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells.
Academic Article	Intracellular human IL-1: a precursor for the secreted monokine.
Concept	Macrophages, Peritoneal
Concept	Macrophages, Alveolar
Concept	Macrophage Activation
Concept	Macrophages
Concept	Macrophage Inflammatory Proteins
Concept	Macrophage-1 Antigen
Concept	Macrophage-Activating Factors
Concept	Macrophage Activation Syndrome
Concept	Granulocyte-Macrophage Colony-Stimulating Factor
Academic Article	Towards a role of interleukin-32 in atherosclerosis.
Academic Article	Interleukin-37.
Academic Article	Interleukin-18, more than a Th1 cytokine.
Academic Article	IL-37 protects against obesity-induced inflammation and insulin resistance.
Academic Article	A 36-year-old woman with recurrent high-grade fevers, hypotension, and hypertriglyceridemia.
Academic Article	Comparison of chemical analyses of hollow-fiber dialyzer extracts.
Academic Article	An anti-inflammatory property of Candida albicans ?-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Academic Article	Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
Academic Article	Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.
Academic Article	Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.
Academic Article	IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.
Academic Article	Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.
Academic Article	IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Academic Article	Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in?vivo.
Academic Article	Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Academic Article	Host and Environmental Factors Influencing Individual Human Cytokine Responses.
Academic Article	Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species.
Academic Article	IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.
Academic Article	OLT1177, a ?-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Academic Article	Blocking IL-1? reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
Academic Article	Role for nuclear interleukin-37 in the suppression of innate immunity.
Academic Article	OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
Academic Article	A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.
Academic Article	Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.
Academic Article	Opposing Effects of Interleukin-36? and Interleukin-38 on Trained Immunity.

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