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Search Results to Charles A Dinarello

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One or more keywords matched the following items that are connected to Dinarello, Charles

Item TypeName
Academic Article Molecular mechanisms in endotoxin fever.
Academic Article Pathogenesis of fever during hemodialysis.
Academic Article Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells.
Academic Article Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro.
Academic Article Does the route of feeding modify the inflammatory response?
Academic Article Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits.
Academic Article Are events after endotoxemia related to circulating phospholipase A2?
Academic Article Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.
Academic Article Ciliary neurotrophic factor is an endogenous pyrogen.
Academic Article Intestinal production of interleukin-1 alpha during endotoxemia in the mouse.
Academic Article Differential regulation of cytokine production in lipopolysaccharide tolerance in mice.
Academic Article Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein.
Academic Article The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice.
Academic Article A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis.
Academic Article Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1.
Academic Article Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels.
Academic Article Expression of interleukin-1 receptor antagonist (IL-1ra) by human circulating polymorphonuclear cells.
Academic Article Effect of endotoxin in IL-1 beta-deficient mice.
Academic Article Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro.
Academic Article Hyperosmotic stress as a stimulant for proinflammatory cytokine production.
Academic Article Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells.
Academic Article Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans.
Academic Article IL-1 beta mediates leptin induction during inflammation.
Academic Article Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice.
Academic Article Leptin deficiency enhances sensitivity to endotoxin-induced lethality.
Academic Article Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes.
Academic Article Dissociation of transcription from translation of human IL-1 beta: induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Soluble murine IL-1 receptor type I induces release of constitutive IL-1 alpha.
Academic Article Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures.
Academic Article Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55.
Academic Article Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemia.
Academic Article Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice.
Academic Article Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia.
Academic Article The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense.
Academic Article Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist.
Academic Article Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1.
Academic Article Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice.
Academic Article IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
Academic Article Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction.
Academic Article Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance.
Academic Article Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells.
Academic Article Fever: links with an ancient receptor.
Academic Article Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells.
Academic Article Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.
Academic Article Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria.
Academic Article Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.
Academic Article Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
Academic Article Interleukin-1 is a mucus secretagogue.
Academic Article Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed.
Academic Article Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
Academic Article Inhibitors of histone deacetylases as anti-inflammatory drugs.
Academic Article Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans.
Academic Article Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.
Academic Article Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells.
Academic Article Dissociation of immunoregulatory function of blood monocytes from maturational state and expression of interleukin-1 in humans chronically infected with Schistosoma mansoni.
Academic Article Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide.
Academic Article Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis.
Academic Article Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level.
Academic Article The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
Academic Article Lipid A, the immunostimulatory principle of lipopolysaccharides?
Academic Article Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells.
Academic Article Eukaryotic translation initiation factor 5A small interference RNA-liposome complexes reduce inflammation and increase survival in murine models of severe sepsis and acute lung injury.
Academic Article Modulation of muramyl dipeptide stimulation of cytokine production by blood components.
Academic Article Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.
Academic Article Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury.
Academic Article A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures.
Academic Article IL-1 induction-capacity of defined lipopolysaccharide partial structures.
Academic Article The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
Academic Article IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Academic Article Membrane interleukin-18 revisits membrane IL-1a in T-helper type 1 responses.
Academic Article Neutrophil-mediated inhibition of proinflammatory cytokine responses.
Academic Article Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro.
Academic Article Self-regulation of procoagulant events on the endothelial cell surface.
Academic Article Detection of interleukin 1 alpha and 1 beta in rabbit tissues during endotoxemia using sensitive radioimmunoassays.
Academic Article Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism.
Academic Article Interleukin-1 receptor type I mRNA in mouse brain as affected by peripheral administration of bacterial lipopolysaccharide.
Academic Article Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.
Academic Article Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and of tumour necrosis factor-alpha ex vivo.
Academic Article Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress.
Academic Article Lipopolysaccharide induces human interleukin-1 receptor antagonist and interleukin-1 production in the same cell.
Academic Article Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
Academic Article Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood.
Academic Article Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.
Academic Article Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.
Academic Article Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Academic Article Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.
Academic Article Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli.
Academic Article Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy.
Academic Article Oxidation of low-density lipoproteins by acellular components of Chlamydia pneumoniae.
Academic Article IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
Academic Article Differential roles of interleukin-18 (IL-18) and IL12 for induction of gamma interferon by staphylococcal cell wall components and superantigens.
Academic Article Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Academic Article Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
Academic Article Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
Academic Article Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits.
Academic Article Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice.
Academic Article Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Academic Article IL-32-dependent effects of IL-1beta on endothelial cell functions.
Academic Article Dissociation of transcription from translation of human IL-1-beta: the induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself.
Academic Article Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.
Academic Article Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.
Academic Article Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1a, IL-1? or IL-1 receptor type I.
Academic Article Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
Academic Article The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis.
Academic Article TREM-1 interaction with the LPS/TLR4 receptor complex.
Academic Article Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade.
Academic Article Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells.
Academic Article C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma.
Academic Article Role of interleukin-1 in the depression of liver drug metabolism by endotoxin.
Academic Article Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide.
Academic Article A new micromethod for determination of interleukin-1 production from frozen human blood mononuclear cells.
Concept Lipopolysaccharides
Academic Article A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma.
Academic Article Anti-inflammatory and immunomodulatory properties of a1-antitrypsin without inhibition of elastase.
Academic Article Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Academic Article Leukocyte activity in patients with ST-segment elevation acute myocardial infarction treated with anakinra.
Academic Article Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
Academic Article Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
Academic Article IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.
Academic Article Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses.
Academic Article Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir.
Academic Article Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.
Academic Article IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells.
Academic Article OLT1177, a ?-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Academic Article Role for nuclear interleukin-37 in the suppression of innate immunity.
Academic Article Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.
Academic Article Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells.
Academic Article A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.
Academic Article IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model.

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