Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Last Name

Contact Us
If you have any questions or feedback please contact us.


Search Results to Charles A Dinarello

This is a "connection" page, showing the details of why an item matched the keywords from your search.


One or more keywords matched the following items that are connected to Dinarello, Charles

Item TypeName
Academic Article The induction of interleukin-1 in humans and its metabolic effects.
Academic Article Fever, interleukin-1 and host defense against malignancy.
Academic Article Control of protein degradation in muscle by prostaglandins, Ca2+, and leukocytic pyrogen (interleukin 1).
Academic Article Pathogenesis of sclerosing peritonitis in CAPD.
Academic Article Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells.
Academic Article The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen.
Academic Article Human leukocytic pyrogen test for detection of pyrogenic material in growth hormone produced by recombinant Escherichia coli.
Academic Article Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma.
Academic Article Demonstration of circulating leukocytic pyrogen/interleukin-1 during fever.
Academic Article Direct effects of a monoclonal B cell differentiation factor and of purified interleukin 1 on B cell differentiation.
Academic Article Immunodeficiency with defective T-cell response to interleukin 1.
Academic Article Production of fever and its effects on the host.
Academic Article Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans.
Academic Article Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation.
Academic Article Molecular basis of fever in humans.
Academic Article Cross-linking of the beta-glucan receptor on human monocytes results in interleukin-1 receptor antagonist but not interleukin-1 production.
Academic Article Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells.
Academic Article Cytokines in acute myocardial infarction: selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist.
Academic Article Synthesis of interleukin-1 beta in primary biliary cirrhosis: relationship to treatment with methotrexate or colchicine and disease progression.
Academic Article Interleukin-1 receptor antagonist suppresses contact hypersensitivity.
Academic Article Cytokines in human renal interstitial fibrosis. I. Interleukin-1 is a paracrine growth factor for cultured fibrosis-derived kidney fibroblasts.
Academic Article Cytokines in human renal interstitial fibrosis. II. Intrinsic interleukin (IL)-1 synthesis and IL-1-dependent production of IL-6 and IL-8 by cultured kidney fibroblasts.
Academic Article Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice.
Academic Article Coagulation of whole blood stimulates interleukin-1 beta gene expression.
Academic Article Blocking interleukin-1 receptors.
Academic Article Induction of circulating soluble tumour necrosis factor receptor and interleukin 1 receptor antagonist following interleukin 1 alpha infusion in humans.
Academic Article The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.
Academic Article Does the route of feeding modify the inflammatory response?
Academic Article Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones.
Academic Article Circulating interleukin-1 receptor antagonist concentrations are increased in adult patients with thermal injury.
Academic Article Balance of synovial fluid IL-1 beta and IL-1 receptor antagonist and recovery from Lyme arthritis.
Academic Article Altered interleukin-1 and tumor necrosis factor production and secretion during pyrogenic tolerance to LPS in rabbits.
Academic Article Modalities for reducing interleukin 1 activity in disease.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.
Academic Article Ciliary neurotrophic factor is an endogenous pyrogen.
Academic Article Interleukin-1 and tumor necrosis factor and their naturally occurring antagonists during hemodialysis.
Academic Article Intestinal production of interleukin-1 alpha during endotoxemia in the mouse.
Academic Article The role of interleukin-1 in host responses to infectious diseases.
Academic Article Anticytokine strategies in the treatment of the systemic inflammatory response syndrome.
Academic Article Induction of circulating IL-1 receptor antagonist by IFN treatment.
Academic Article Differential regulation of cytokine production in lipopolysaccharide tolerance in mice.
Academic Article Interleukin-1 receptor antagonist inhibits subcutaneous B16 melanoma growth in vivo.
Academic Article Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells.
Academic Article Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1.
Academic Article Interleukin-1 pretreatment protects against endotoxin-induced hypotension in rabbits: association with decreased tumor necrosis factor levels.
Academic Article The interleukin-1 receptor antagonist can either reduce or enhance the lethality of Klebsiella pneumoniae sepsis in newborn rats.
Academic Article Expression of interleukin-1 receptor antagonist (IL-1ra) by human circulating polymorphonuclear cells.
Academic Article Role of interleukin 1 in antigen-specific T cell proliferation.
Academic Article Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.
Academic Article Effect of endotoxin in IL-1 beta-deficient mice.
Academic Article Cytokines as mediators in the pathogenesis of septic shock.
Academic Article Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro.
Academic Article Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis.
Academic Article Mechanism of action of cyclosporin A. Effect on T-cell-binding of interleukin 1 and antagonizing effect of insulin.
Academic Article Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans.
Academic Article Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.
Academic Article Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever.
Academic Article Reduction of inflammation by decreasing production of interleukin-1 or by specific receptor antagonism.
Academic Article Interleukin-1 and interleukin-1 receptor antagonist.
Academic Article Three distinct promoters direct transcription of different 5' untranslated regions of the human interleukin 1 type I receptor: a possible mechanism for control of translation.
Academic Article Hyperosmotic stress as a stimulant for proinflammatory cytokine production.
Academic Article Glycosylation of the interleukin-1 receptor type I is required for optimal binding of interleukin-1.
Academic Article Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells.
Academic Article Response to local inflammation of IL-1 beta-converting enzyme- deficient mice.
Academic Article The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity.
Academic Article The natural interleukin-1 receptor antagonist in term and preterm parturition.
Academic Article Blocking interleukin-1 and tumor necrosis factor in disease.
Academic Article Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice.
Academic Article Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro.
Academic Article [Phosphatidylcholine induces an increase in the production of interleukin-6 and improves survival of rats with neonatal sepsis caused by Klebsiella pneumoniae].
Academic Article Correlation of serum levels of interleukin-1 family members with disease activity and response to treatment in hairy cell leukemia.
Academic Article Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.
Academic Article Modulation of acute myeloblastic leukemia (AML) cell proliferation and blast colony formation by antisense oligomer for IL-1 beta converting enzyme (ICE) and IL-1 receptor antagonist (IL-1ra).
Academic Article [Antagonists in neonatal sepsis].
Academic Article The biological properties of interleukin-1.
Academic Article A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses.
Academic Article Differential effects of interleukin-1 and tumor necrosis factor on ketogenesis.
Academic Article Leptin deficiency enhances sensitivity to endotoxin-induced lethality.
Academic Article IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family.
Academic Article Suppression of IL-2-induced SAA gene expression in mice by the administration of an IL-1 receptor antagonist.
Academic Article Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes.
Academic Article Dissociation of transcription from translation of human IL-1 beta: induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Monokine antagonism is reduced in patients with IDDM.
Academic Article Soluble murine IL-1 receptor type I induces release of constitutive IL-1 alpha.
Academic Article Interleukin 18 stimulates HIV type 1 in monocytic cells.
Academic Article Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures.
Academic Article The biology of interleukin-1.
Academic Article Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).
Academic Article Elevated circulating levels of soluble interleukin-1 receptor type II during interleukin-2 immunotherapy.
Academic Article Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus.
Academic Article Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.
Academic Article Blocking interleukin-1 in disease.
Academic Article Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.
Academic Article Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment.
Academic Article Interleukin-6 and tumor necrosis factor in cerebrospinal fluid: changes during pyrogen fever.
Academic Article Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits.
Academic Article IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.
Academic Article Is there an interleukin-1 genetic predisposition to developing severe sepsis?
Academic Article Modalities for reducing interleukin 1 activity in disease.
Academic Article IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor.
Academic Article Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice.
Academic Article Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia.
Academic Article The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense.
Academic Article Angiotensin-converting-enzyme inhibitors suppress synthesis of tumour necrosis factor and interleukin 1 by human peripheral blood mononuclear cells.
Academic Article Osmotic regulation of cytokine synthesis in vitro.
Academic Article Biologic basis for interleukin-1 in disease.
Academic Article Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain.
Academic Article The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1.
Academic Article Tumor necrosis factor (TNF)-alpha-induced interleukin-8 in human blood cultures discriminates neutralization by the p55 and p75 TNF soluble receptors.
Academic Article Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist.
Academic Article Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases.
Academic Article An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding.
Academic Article The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment.
Academic Article Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18.
Academic Article Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma.
Academic Article Effect of interleukin-18 on mouse core body temperature.
Academic Article Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production.
Academic Article Novel targets for interleukin 18 binding protein.
Academic Article Hyperresponsive febrile reactions to interleukin (IL) 1alpha and IL-1beta, and altered brain cytokine mRNA and serum cytokine levels, in IL-1beta-deficient mice.
Academic Article IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.
Academic Article The pattern of interleukin-1beta (IL-1beta) and its modulating agents IL-1 receptor antagonist and IL-1 soluble receptor type II in acute meningococcal infections.
Academic Article Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants.
Academic Article Anti-cytokine therapies in response to systemic infection.
Academic Article Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.
Academic Article Role of interleukin-18 in host defense against disseminated Candida albicans infection.
Academic Article Rat interleukin-18 binding protein: cloning, expression, and characterization.
Academic Article Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1 beta activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein.
Academic Article Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction.
Academic Article Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
Academic Article Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells.
Academic Article Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study.
Academic Article Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.
Academic Article Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance.
Academic Article Taurolidine, an analogue of the amino acid taurine, suppresses interleukin 1 and tumor necrosis factor synthesis in human peripheral blood mononuclear cells.
Academic Article A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits.
Academic Article Setting the cytokine trap for autoimmunity.
Academic Article Enhancement of growth of virulent strains of Escherichia coli by interleukin-1.
Academic Article Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein.
Academic Article Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells.
Academic Article Transcription, translation and secretion of interleukin 1 and tumor necrosis factor: effects of tebufelone, a dual cyclooxygenase/5-lipoxygenase inhibitor.
Academic Article A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development.
Academic Article Interleukin 4 (IL) 4 up-regulates gene and surface IL 1 receptor type I in murine T helper type 2 cells.
Academic Article Fever: links with an ancient receptor.
Academic Article P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression.
Academic Article Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.
Academic Article Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro.
Academic Article The specific IL-1 inhibitor from the human M20 cell line is distinct from the IL-1 receptor antagonist.
Academic Article Interleukin-18 and the treatment of rheumatoid arthritis.
Academic Article Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.
Academic Article Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
Academic Article Differential effects of IL-1 alpha and IL-1 beta on tumorigenicity patterns and invasiveness.
Academic Article Mutation scan of a type 1 diabetes candidate gene: the human interleukin-18 binding protein gene.
Academic Article Chlamydia pneumoniae stimulates IFN-gamma synthesis through MyD88-dependent, TLR2- and TLR4-independent induction of IL-18 release.
Academic Article Interleukin-1 is a mucus secretagogue.
Academic Article Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein.
Academic Article Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
Academic Article Interleukin-1 gene expression in rabbit vascular tissue in vivo.
Academic Article Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events.
Academic Article Blocking IL-1 in systemic inflammation.
Academic Article IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Academic Article Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules.
Academic Article Proteinase 3 is an IL-32 binding protein.
Academic Article Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells.
Academic Article Immunoregulatory functions of paf-acether. IV. Enhancement of IL-1 production by muramyl dipeptide-stimulated monocytes.
Academic Article The paradox of pro-inflammatory cytokines in cancer.
Academic Article Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2.
Academic Article IL-32, a novel cytokine with a possible role in disease.
Academic Article Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney.
Academic Article Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism.
Academic Article Effect of a four-week course of interleukin-10 on cytokine production in a placebo-controlled study of HIV-1-infected subjects.
Academic Article Interleukin-1, anorexia, and dietary fatty acids.
Academic Article Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911.
Academic Article Differential effects of anti-IL-1R accessory protein antibodies on IL-1alpha or IL-1beta-induced production of PGE(2) and IL-6 from 3T3-L1 cells.
Academic Article Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1).
Academic Article Intrinsic pituitary interleukin-1 beta is induced by bacterial lipopolysaccharide.
Academic Article Sustained delivery of IL-1 Ra from biodegradable microspheres reduces the number of murine B16 melanoma lung metastases.
Academic Article Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis.
Academic Article Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level.
Academic Article Neonatal interleukin-1 beta, interleukin-6, and tumor necrosis factor: cord blood levels and cellular production.
Academic Article Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice.
Academic Article The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
Academic Article Lipid A, the immunostimulatory principle of lipopolysaccharides?
Academic Article Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury.
Academic Article Targeting the pathogenic role of interleukin 1{beta} in the progression of smoldering/indolent myeloma to active disease.
Academic Article Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood.
Academic Article IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation.
Academic Article IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
Academic Article Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.
Academic Article Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.
Academic Article Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro.
Academic Article New concepts on the pathogenesis of fever.
Academic Article Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.
Academic Article IL-1 production by T6 (CD1a) positive cord blood mononuclear cells (Langerhan's cell precursors?).
Academic Article IL-1: discoveries, controversies and future directions.
Academic Article Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta.
Academic Article Interleukin-18 treatment options for inflammatory diseases.
Academic Article IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2.
Academic Article The endogenous pyrogens in host-defense interactions.
Academic Article Interleukin-1 and the effects of cyclooxygenase inhibitors on its biological activities.
Academic Article Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury.
Academic Article Interleukin-1 and its receptor.
Academic Article Role of IL-1beta in type 2 diabetes.
Academic Article Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3.
Academic Article IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.
Academic Article Adult-onset Still's disease with myocarditis successfully treated with the interleukin-1 receptor antagonist anakinra.
Academic Article Blocking interleukin-1ß in acute and chronic autoinflammatory diseases.
Academic Article Serum and urinary levels of IL-18 and its inhibitor IL-18BP in systemic lupus erythematosus.
Academic Article The in vivo and in vitro effects of interleukin-1 and tumor necrosis factor on murine cytomegalovirus infection.
Academic Article Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1a.
Academic Article Synergy of helper factors in the differentiation of in vivo-preactivated antigen-specific human B cells.
Academic Article The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro.
Academic Article Protection from RNA and DNA viruses by IL-32.
Academic Article Regulation of eicosanoid production in rabbit colon by interleukin-1.
Academic Article Anakinra for the inflammatory complications of chronic granulomatous disease.
Academic Article Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia.
Academic Article IL-1 induction-capacity of defined lipopolysaccharide partial structures.
Academic Article Interleukin-18, a proinflammatory cytokine.
Academic Article Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta.
Academic Article Interleukin-1 and the response to injury.
Academic Article Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.
Academic Article [Cytokines in the pathogenesis of fever].
Academic Article Interleukin 37 expression protects mice from colitis.
Academic Article Inhibition of IL-32 activation by a-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
Academic Article IL-1a and IL-1ß recruit different myeloid cells and promote different stages of sterile inflammation.
Academic Article Interplay between redox status and inflammasome activation.
Academic Article ß2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo.
Academic Article IL-37: a new anti-inflammatory cytokine of the IL-1 family.
Academic Article IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.
Academic Article Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis.
Academic Article Interleukin-1ß-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behcet's disease: an open-label pilot study.
Academic Article Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1a.
Academic Article Interleukin 32 (IL-32) contains a typical a-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.
Academic Article IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Academic Article Interleukin-1 and inhibition of interleukin-1 in hemodialysis patients.
Academic Article The combination of soluble IL-18Ralpha and IL-18Rbeta chains inhibits IL-18-induced IFN-gamma.
Academic Article IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.
Academic Article Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of ibuprofen.
Academic Article Interleukin-1-induced anorexia in the rat. Influence of prostaglandins.
Academic Article Interleukin-32: a predominantly intracellular proinflammatory mediator that controls cell activation and cell death.
Academic Article Protection from inflammatory organ damage in a murine model of hemophagocytic lymphohistiocytosis using treatment with IL-18 binding protein.
Academic Article The stimulation of collagenase production in rabbit articular chondrocytes by interleukin-1 is increased by collagens.
Academic Article The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses.
Academic Article Role of IL-18 in second-hand smoke-induced emphysema.
Academic Article Enhancement of in-vitro human interleukin-1 production by sodium acetate.
Academic Article IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor.
Academic Article The role of interleukin 1 (IL 1) in tumor-NK cell interactions: correction of defective NK cell activity in cancer patients by treating target cells with IL 1.
Academic Article Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones.
Academic Article Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
Academic Article Multiple biological properties of recombinant human interleukin 1 (beta).
Academic Article Ultrafiltration to reject human interleukin-1-inducing substances derived from bacterial cultures.
Academic Article Interleukin-1 in the pathogenesis of fever.
Academic Article Interleukin-1 activation and acute phase response during hemodialysis.
Academic Article Chemical characterization of an interleukin-1-inducing substance derived from human mixed leukocyte reactions: IL-1-inducing substance is not gamma interferon.
Academic Article Central effects of vasopressin and 1-desamino-8-D-arginine vasopressin (DDAVP) on interleukin-1 fever in the rat.
Academic Article Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.
Academic Article Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.
Academic Article Occurrence of interleukin-1 in cerebrospinal fluid of the conscious cat.
Academic Article Studies on the ability of hemodialysis membranes to induce, bind, and clear human interleukin-1.
Academic Article Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type.
Academic Article Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells.
Academic Article Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1.
Academic Article Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate.
Academic Article Interleukin-1 and biocompatibility in haemodialysis.
Academic Article Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.
Academic Article Interleukin-1 stimulation in the ESRD patient: potential long-term consequences.
Academic Article Changes in energy expenditure and fat metabolism in rats infused with interleukin-1.
Academic Article Interleukin-1.
Academic Article IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma.
Academic Article Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.
Academic Article Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.
Academic Article Induction of interleukin 1 by synthetic and naturally occurring muramyl peptides.
Academic Article Interleukin-1: the pros and cons of its clinical relevance.
Academic Article C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha.
Academic Article Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients.
Academic Article Endogenous pyrogens.
Academic Article The relationship between biocompatibility and interleukin-1.
Academic Article Interleukins.
Academic Article Interleukin-1--its multiple biological effects and its association with hemodialysis.
Academic Article The role of interferon-beta 1 and the 26-kDa protein (interferon-beta 2) as mediators of the antiviral effect of interleukin 1 and tumor necrosis factor.
Academic Article Interleukin 1 dose-dependently affects the biosynthesis of (pro)insulin in isolated rat islets of Langerhans.
Academic Article Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production.
Academic Article Human and murine interleukin 1 possess sequence and structural similarities.
Academic Article Purification and characterization of a unique human interleukin 1 from the tumor cell line U937.
Academic Article Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid.
Academic Article Human thymic epithelial cells produce interleukin 1.
Academic Article Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia.
Academic Article Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes.
Academic Article Effects of human interleukin 1 and human tumor necrosis factor on human T lymphocyte colony formation.
Academic Article Development and use of a radioimmunoassay for human interleukin-1 beta.
Academic Article Interleukin 1 production by human lung tissue. I. Identification and characterization.
Academic Article Prostaglandin formation in feline cerebral microvessels: effect of endotoxin and interleukin-1.
Academic Article Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans.
Academic Article Acute inflammation in gram-negative infection: endotoxin, interleukin 1, tumor necrosis factor, and neutrophils.
Academic Article Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease.
Academic Article Detection of interleukin 1 alpha and 1 beta in rabbit tissues during endotoxemia using sensitive radioimmunoassays.
Academic Article Interleukin-1 and the pathogenesis of the acute-phase response.
Academic Article Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin.
Academic Article The biology of SAA: identification of the inducer, in vitro synthesis, and heterogeneity demonstrated with monoclonal antibodies.
Academic Article Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor.
Academic Article Production of leukocytic pyrogen from phagocytes of neonates.
Academic Article Interleukin-1 and interleukin-1 receptor antagonist production during haemodialysis: which cytokine is a surrogate marker for dialysis-related complications?
Academic Article Interleukin-1 augments gamma-aminobutyric acidA receptor function in brain.
Academic Article IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease.
Academic Article Is there a role for interleukin-1 blockade in intravenous immunoglobulin therapy?
Academic Article Interleukin-1 receptor antagonist: an index of dialysis-induced interleukin-1 production.
Academic Article Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia.
Academic Article Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism.
Academic Article Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone.
Academic Article The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription.
Academic Article The interleukin-1 family: 10 years of discovery.
Academic Article Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds.
Academic Article Plasma levels of IL-1 beta, TNF alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients.
Academic Article Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation.
Academic Article Comparison of first use and reuse of cuprophan membranes on interleukin-1 receptor antagonist and interleukin-1 beta production by blood mononuclear cells.
Academic Article Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats.
Academic Article Gene expression of interleukin-1 beta during hemodialysis.
Academic Article Identification of the promoter region of human interleukin 1 type I receptor gene: multiple initiation sites, high G+C content, and constitutive expression.
Academic Article Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and of tumour necrosis factor-alpha ex vivo.
Academic Article High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis.
Academic Article Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress.
Academic Article Transfer of cytokine-inducing bacterial products across hemodialyzer membranes in the presence of plasma or whole blood.
Academic Article Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis.
Academic Article Induction of interleukin-1 and interleukin-1 receptor antagonist.
Academic Article Physiological and cytokine responses in IL-1 beta-deficient mice after zymosan-induced inflammation.
Academic Article Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice.
Academic Article Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
Academic Article The many worlds of reducing interleukin-1.
Academic Article Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome.
Academic Article Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood.
Academic Article Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.
Academic Article Interleukin-1.
Academic Article Overview of interleukin-18: more than an interferon-gamma inducing factor.
Academic Article Elevated levels of soluble interleukin-1 receptor type II and interleukin-1 receptor antagonist in patients with chronic arthritis: correlations with markers of inflammation and joint destruction.
Academic Article New polyether sulfone dialyzers attenuate passage of cytokine-inducing substances from pseudomonas aeruginosa contaminated dialysate.
Academic Article Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.
Academic Article Phase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera.
Academic Article Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Academic Article Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells.
Academic Article Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.
Academic Article Cytokines as endogenous pyrogens.
Academic Article Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression.
Academic Article Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta.
Academic Article Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock-like state and tissue injury in rabbits without endotoxemia. Comparison to Escherichia coli.
Academic Article Modulatory in vitro effects of interleukin-1 receptor antagonist (IL-1Ra) or antisense oligonucleotide to interleukin-1 beta converting enzyme (ICE) on acute myeloid leukaemia (AML) cell growth.
Academic Article Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy.
Academic Article Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Academic Article IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
Academic Article Targeting interleukin 18 with interleukin 18 binding protein.
Academic Article Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression.
Academic Article Differential roles of interleukin-18 (IL-18) and IL12 for induction of gamma interferon by staphylococcal cell wall components and superantigens.
Academic Article Tumor necrosis factor-alpha, interleukin-1, and interferon alpha stimulate triglyceride synthesis in HepG2 cells.
Academic Article Interleukin-18 inhibits human immunodeficiency virus type 1 production in peripheral blood mononuclear cells.
Academic Article Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels.
Academic Article Ultrafiltration to remove endotoxins and other cytokine-inducing materials from tissue culture media and parenteral fluids.
Academic Article IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
Academic Article The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures.
Academic Article Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium.
Academic Article IL-1 is required for tumor invasiveness and angiogenesis.
Academic Article Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure.
Academic Article Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity?
Academic Article Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
Academic Article Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
Academic Article Differences in signaling pathways by IL-1beta and IL-18.
Academic Article Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease.
Academic Article Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha.
Academic Article Interleukin-32: a cytokine and inducer of TNFalpha.
Academic Article Comparison of the effect of interleukin 6 and interleukin 1 on collagenase and proteoglycan production by chondrocytes.
Academic Article A signal for the caspase-1 inflammasome free of TLR.
Academic Article Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.
Academic Article Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle.
Academic Article Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha.
Academic Article IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Academic Article Effect of interleukin-1 on lipid metabolism in the rat. Similarities to and differences from tumor necrosis factor.
Academic Article Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha.
Academic Article CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells.
Academic Article Interleukin-1beta.
Academic Article Effects of omega 3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. Comparison with oral aspirin and ibuprofen.
Academic Article Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6.
Academic Article Immune phenomena involved in the in vivo regression of fibrosarcoma cells expressing cell-associated IL-1alpha.
Academic Article Interleukin-1 is released at sites of human cutaneous allergic reactions.
Academic Article Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
Academic Article Interleukin-32 induces the differentiation of monocytes into macrophage-like cells.
Academic Article Cytokines link Toll-like receptor 4 signaling to cardiac dysfunction after global myocardial ischemia.
Academic Article Transcription, not synthesis, of interleukin-1 and tumor necrosis factor by complement.
Academic Article Endogenous IL-32 controls cytokine and HIV-1 production.
Academic Article Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor.
Academic Article Interleukin 1 receptors and biological responses.
Academic Article Inhibitory effects of elevated temperature on human cytokine production and natural killer activity.
Academic Article Intravitreal anakinra inhibits choroidal neovascular membrane growth in a rat model.
Academic Article NIH conference. Immunomodulators in clinical medicine.
Academic Article High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein.
Academic Article Interleukin-18 and the pathogenesis of inflammatory diseases.
Academic Article IL-18 in autoimmunity: review.
Academic Article Inflammatory markers and the risk of Alzheimer disease: the Framingham Study.
Academic Article IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.
Academic Article Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
Academic Article Dissociation of transcription from translation of human IL-1-beta: the induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity.
Academic Article Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factor.
Academic Article Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.
Academic Article Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
Academic Article Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.
Academic Article Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.
Academic Article Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA.
Academic Article Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).
Academic Article Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins.
Academic Article Interleukin-18 binding protein in the sera of patients with Wegener's granulomatosis.
Academic Article Impaired counter-regulation of interleukin-1 by the soluble IL-1 receptor type II in patients with chronic liver disease.
Academic Article IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease.
Academic Article Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors.
Academic Article Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1a, IL-1ß or IL-1 receptor type I.
Academic Article Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
Academic Article IL-1ß regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.
Academic Article Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain.
Academic Article Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.
Academic Article Immunological and inflammatory functions of the interleukin-1 family.
Academic Article Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.
Academic Article Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
Academic Article Circulating lymphokine levels in the chronic fatigue syndrome.
Academic Article Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells.
Academic Article Lack of interleukin-1a or interleukin-1ß inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice.
Academic Article Lymphokines.
Academic Article Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation.
Academic Article Interleukin-1-induced sleep and febrile responses differentially altered by a muramyl dipeptide derivative.
Academic Article Plasmapheresis for fulminant meningococcemia.
Academic Article Why not treat human cancer with interleukin-1 blockade?
Academic Article In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation.
Academic Article The interleukin 1 receptor.
Academic Article Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens.
Academic Article Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis.
Academic Article More than inflammation: interleukin-1beta polymorphisms and the lipid metabolism.
Academic Article Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade.
Academic Article Interleukin-1 in the pathogenesis and treatment of inflammatory diseases.
Academic Article Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).
Academic Article The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering.
Academic Article Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease.
Academic Article The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1ß.
Academic Article Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells.
Academic Article Role for interleukin-1 in the pathogenesis of hypersensitivity diseases.
Academic Article The lysine deacetylase inhibitor Givinostat inhibits ß-cell IL-1ß induced IL-1ß transcription and processing.
Academic Article Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1.
Academic Article Interaction of IL 1 and TPA in modulation of eosinophil function.
Academic Article Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes.
Academic Article The effect of interleukin 1 on IgG synthesis in systemic lupus erythematosus.
Academic Article Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
Academic Article Interleukin-1 beta in human plasma: optimization of blood collection, plasma extraction, and radioimmunoassay methods.
Academic Article Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling.
Academic Article Studies on the biological properties of purified and recombinant human interleukin-1.
Academic Article Role of interleukin-1 in the depression of liver drug metabolism by endotoxin.
Academic Article Inducible interleukin-1 gene expression in human vascular smooth muscle cells.
Academic Article Studies on the molecular nature of human interleukin 1.
Academic Article Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury.
Academic Article Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans.
Academic Article Modulation of endothelial cell functions by different molecular species of interleukin 1.
Academic Article CAPD is a second-class treatment.
Academic Article Increased interleukin 1 beta in human skeletal muscle after exercise.
Academic Article Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.
Academic Article Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis.
Academic Article A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia.
Academic Article Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells.
Academic Article Keep up the heat on IL-1.
Academic Article Detection of circulating tumor necrosis factor after endotoxin administration.
Academic Article Effect of recombinant a1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes.
Academic Article Interleukin-1 is a chemotactic factor for human T-lymphocytes.
Academic Article Interleukin-1 and glucocorticoid hormones integrate an immunoregulatory feedback circuit.
Academic Article Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain.
Academic Article Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.
Academic Article Interleukin-1 and dialysis.
Academic Article A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection.
Academic Article The biology of interleukin 1 and comparison to tumor necrosis factor.
Academic Article Effects of leukocytic pyrogen (interleukin-1) on local cerebral glucose utilization in rats with and without premedication with indomethacin or dexamethasone.
Academic Article Recombinant human interleukin-1 beta causes histamine release from human basophils.
Academic Article Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels.
Academic Article Induction of interleukin-1 during CAPD.
Academic Article Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.
Academic Article Brain temperature changes coupled to sleep states persist during interleukin 1-enhanced sleep.
Academic Article Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.
Academic Article Human interleukin-1 production during hemodialysis.
Academic Article Physiological mechanisms contributing to increased interleukin-1 secretion.
Academic Article Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line.
Academic Article Direct stimulation of the adrenal cortex by interleukin-1.
Academic Article Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1.
Academic Article Role of interleukin-1 and tumour necrosis factor-alpha in acute inflammation.
Academic Article Multiple biological activities of human recombinant interleukin 1.
Academic Article Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.
Academic Article Differential effects of human interleukin-1 on growth of human fibroblasts and vascular smooth muscle cells.
Academic Article Parasite-monocyte interactions in human leishmaniasis: production of interleukin-1 in vitro.
Concept Interleukin-1alpha
Concept Interleukin-1 Receptor Accessory Protein
Concept Interleukin-18 Receptor alpha Subunit
Concept Interleukin-1
Concept Interleukin 1 Receptor Antagonist Protein
Concept Interleukin-10
Concept Receptors, Interleukin-1
Concept Receptors, Interleukin-2
Concept Interleukin-17
Concept Receptors, Interleukin-6
Concept Interleukin-1beta
Concept Interleukin-8
Concept Interleukin-23
Concept Receptors, Interleukin-1 Type I
Concept Interleukin-4
Concept Interleukin-6
Concept Receptors, Interleukin
Concept Interleukin-18
Concept Interleukin-12
Concept Receptors, Interleukin-18
Concept Interleukin-11
Concept Receptors, Interleukin-1 Type II
Concept Interleukin-2
Concept Interleukin-3
Academic Article A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma.
Academic Article Towards a role of interleukin-32 in atherosclerosis.
Academic Article The C3a receptor, caspase-1, and release of IL-1ß.
Academic Article Effects of interleukin-1 blockade with anakinra on aerobic exercise capacity in patients with heart failure and preserved ejection fraction (from the D-HART pilot study).
Academic Article The Interleukin-1a Precursor is Biologically Active and is Likely a Key Alarmin in the IL-1 Family of Cytokines.
Academic Article The interleukin-1 family: back to the future.
Academic Article IL-32 promotes angiogenesis.
Academic Article Novel insights into the biology of interleukin-32.
Academic Article Treating inflammation by blocking interleukin-1 in humans.
Academic Article Interleukin-1ß in innate inflammation, autophagy and immunity.
Academic Article Interleukin-18, more than a Th1 cytokine.
Academic Article Interleukin-1 blockade in rheumatoid arthritis and heart failure: a missed opportunity?
Academic Article Interleukin-10 in patients with ST-segment elevation myocardial infarction.
Academic Article Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Academic Article Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.
Academic Article IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.
Academic Article Non-redundant properties of IL-1a and IL-1ß during acute colon inflammation in mice.
Academic Article Interleukin-1a neutralisation in patients with cancer.
Academic Article Interleukin-18 and IL-18 binding protein.
Academic Article a1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1ß responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.
Academic Article Interleukin-1 affects the function of cultured human thyroid cells.
Academic Article Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells.
Academic Article IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis.
Academic Article Clinical predictors of response to anakinra in patients with heart failure.
Academic Article Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study.
Academic Article Interleukin-1 antagonists.
Academic Article Clone controversy at Immunex.
Academic Article Serum interleukin-1 (IL-1) activity in alcoholic hepatitis.
Academic Article Interleukin-1 in disease.
Academic Article Innate cytokines dictate the fate of acute intestinal inflammation.
Academic Article An expanding role for interleukin-1 blockade from gout to cancer.
Academic Article Comparison of chemical analyses of hollow-fiber dialyzer extracts.
Academic Article Anti-interleukin-1 reactive cells in Hodgkin's disease.
Academic Article How interleukin-1ß induces gouty arthritis.
Academic Article Isolation of an interleukin-1-like factor from human joint effusions.
Academic Article Interleukin 1 reduces opioid binding in guinea pig brain.
Academic Article Interleukin-1 immunoreactive innervation of the human hypothalamus.
Academic Article Anti-inflammatory therapies in acute coronary syndromes: is IL-1 blockade a solution?
Academic Article Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
Academic Article An anti-inflammatory property of Candida albicans ß-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Academic Article Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot studies).
Academic Article Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
Academic Article Treating pulmonary silicosis by blocking interleukin 1.
Academic Article ATP-Induced IL-1ß Specific Secretion: True Under Stringent Conditions.
Academic Article Inflammasome-independent regulation of IL-1-family cytokines.
Academic Article Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.
Academic Article Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.
Academic Article Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance.
Academic Article Anakinra treatment in drug-resistant Behcet's disease: a case series.
Academic Article Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade.
Academic Article Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir.
Academic Article IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.
Academic Article IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance.
Academic Article The role of interleukin-32 against tuberculosis.
Academic Article Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial.
Academic Article IL-1a is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.
Academic Article Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies.
Academic Article Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial.
Academic Article Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.
Academic Article Corrigendum: IL-1a is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.
Academic Article Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines.
Academic Article Beneficial effects of IL-37 after spinal cord injury in mice.
Academic Article IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Academic Article Reduction in C-reactive protein indicates successful targeting of the IL-1/IL-6 axis resulting in improved survival in early stage multiple myeloma.
Academic Article Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study.
Academic Article Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.
Academic Article Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection.
Academic Article IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis.
Academic Article a-Linoleic acid enhances the capacity of a-1 antitrypsin to inhibit lipopolysaccharide induced IL-1ß in human blood neutrophils.
Academic Article IL-1 Inhibition and Vascular Function in CKD.
Academic Article Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species.
Academic Article Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure.
Academic Article Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice.
Academic Article Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.
Academic Article Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.
Academic Article Implication of the intestinal microbiome as a potential surrogate marker of immune responsiveness to experimental therapies in autoimmune diabetes.
Grant Pathogenesis of Fever in Man
Grant Pathogenesis of Fever in Man
Academic Article Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.
Academic Article Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.
Academic Article IL-18 binding protein reverses the life-threatening hyperinflammation of a baby with the NLRC4 mutation.
Academic Article IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.
Academic Article IL-32? promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis.
Academic Article The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice.
Grant Molecular Mechanisms of Cytokine Induced Insulin Resistance
Academic Article Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.
Academic Article MABp1 Targeting IL-1a for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study.
Academic Article Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease.
Academic Article Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity.
Academic Article Biology of IL-38 and its role in disease.
Academic Article OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Academic Article Human Interleukin-32? Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.
Academic Article Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes.
Academic Article IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.
Academic Article Treatment of Dilated Cardiomyopathy With Interleukin-1 Inhibition.
Academic Article TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization.
Academic Article IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment.
Academic Article The Inter-Relationship of Platelets with Interleukin-1ß-Mediated Inflammation in Humans.
Academic Article Blocking IL-1ß reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
Academic Article Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1a antibody, in a phase III randomized study of advanced colorectal cancer.
Academic Article Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression.
Academic Article Role for nuclear interleukin-37 in the suppression of innate immunity.
Academic Article Interleukin-37 monomer is the active form for reducing innate immunity.
Concept Interleukin-33
Academic Article Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.
Academic Article Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome.
Academic Article The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis.
Academic Article IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
Academic Article The IL-1 family of cytokines and receptors in rheumatic diseases.
Academic Article Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.
Academic Article Interleukin-37 Inhibits Colon Carcinogensis During Chronic Colitis.
Academic Article PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis.
Academic Article Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.
Academic Article MABp1 targeting interleukin-1a in hidradenitis suppurativa ineligible for adalimumab treatment: results of the open-label extension period.
Academic Article Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19.
Academic Article Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects.
Academic Article IL-37 Expression Is Downregulated in Lesional Psoriasis Skin.
Academic Article Treatment of Inflammatory Diseases with IL-1 Blockade.
Academic Article IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8.
Academic Article Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.
Academic Article Interleukin 1a: a comprehensive review on the role of IL-1a in the pathogenesis and treatment of autoimmune and inflammatory diseases.
Academic Article Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells.
Academic Article IL-38 prevents induction of trained immunity by inhibition of mTOR signaling.
Academic Article Modulation of Liver Inflammation and Fibrosis by Interleukin-37.
Academic Article The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.
Academic Article Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses.
Academic Article Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation.
Academic Article Tumor NLRP3-Derived IL-1ß Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression.
Academic Article Interleukin-1 Receptor Antagonism Abrogates Acute Pressure Overload-Induced Murine Heart Failure.
Academic Article IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33.
Academic Article Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
Academic Article Interleukin-38 in Health and Disease.
Academic Article Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs.
Academic Article IL-38 Gene Deletion Worsens Murine Colitis.
Academic Article Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions.

Search Criteria
  • Interleukin 6

Copyright © 2022 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)