Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.
Back to Search Results

Connection

Search Results to Charles A Dinarello

This is a "connection" page, showing the details of why an item matched the keywords from your search.

                     
                     

One or more keywords matched the following items that are connected to Dinarello, Charles

Item TypeName
Academic Article The induction of interleukin-1 in humans and its metabolic effects.
Academic Article Clinical evaluation of the immunoadjuvant murabutide, a derivative of MDP, administered with a tetanus toxoid vaccine.
Academic Article An update on human interleukin-1: from molecular biology to clinical relevance.
Academic Article Colchicine therapy for familial mediterranean fever. A double-blind trial.
Academic Article Colchicine therapy of familial Mediterranean fever.
Academic Article A primate model for the study of human fever.
Academic Article Fever, interleukin-1 and host defense against malignancy.
Academic Article Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
Academic Article Pathogenesis of sclerosing peritonitis in CAPD.
Academic Article Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells.
Academic Article The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen.
Academic Article The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1).
Academic Article A comparison of neutralizing and antigen-binding assays for human antibodies against toxic-shock-syndrome toxin 1.
Academic Article Human leukocytic pyrogen test for detection of pyrogenic material in growth hormone produced by recombinant Escherichia coli.
Academic Article Mechanisms of fever induced by recombinant human interferon.
Academic Article The effects of interleukin 1 on human B cell activation and proliferation.
Academic Article Molecular mechanisms in endotoxin fever.
Academic Article Fibroblast stimulation in schistosomiasis. V. Egg granuloma macrophages spontaneously secrete a fibroblast-stimulating factor.
Academic Article Sleep-promoting effects of endogenous pyrogen (interleukin-1).
Academic Article Induction of hepatic protein synthesis by a peptide in blood plasma of patients with sepsis and trauma.
Academic Article Demonstration of circulating leukocytic pyrogen/interleukin-1 during fever.
Academic Article Induction of human interleukin-1 by a product of Staphylococcus aureus associated with toxic shock syndrome.
Academic Article Direct effects of a monoclonal B cell differentiation factor and of purified interleukin 1 on B cell differentiation.
Academic Article Immunodeficiency with defective T-cell response to interleukin 1.
Academic Article Production of fever and its effects on the host.
Academic Article Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans.
Academic Article Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation.
Academic Article Pathogenesis of fever during hemodialysis.
Academic Article Molecular basis of fever in humans.
Academic Article Haptoglobin and albumin synthesis in isolated rat hepatocytes. Response to potential mediators of the acute-phase reaction.
Academic Article Cross-linking of the beta-glucan receptor on human monocytes results in interleukin-1 receptor antagonist but not interleukin-1 production.
Academic Article Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism.
Academic Article Human vascular smooth muscle cells produce an intracellular form of interleukin-1 receptor antagonist.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells.
Academic Article Cytokines in acute myocardial infarction: selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist.
Academic Article Cytokine-processing enzymes. Stopping the cuts.
Academic Article Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes--evidence for polygenicity in man. Danish Study Group of Diabetes in Childhood.
Academic Article Synthesis of interleukin-1 beta in primary biliary cirrhosis: relationship to treatment with methotrexate or colchicine and disease progression.
Academic Article Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells.
Academic Article Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans.
Academic Article Cytokines in human renal interstitial fibrosis. I. Interleukin-1 is a paracrine growth factor for cultured fibrosis-derived kidney fibroblasts.
Academic Article Cytokines in human renal interstitial fibrosis. II. Intrinsic interleukin (IL)-1 synthesis and IL-1-dependent production of IL-6 and IL-8 by cultured kidney fibroblasts.
Academic Article Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice.
Academic Article Coagulation of whole blood stimulates interleukin-1 beta gene expression.
Academic Article Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10.
Academic Article Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation.
Academic Article Blocking interleukin-1 receptors.
Academic Article Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro.
Academic Article Induction of circulating soluble tumour necrosis factor receptor and interleukin 1 receptor antagonist following interleukin 1 alpha infusion in humans.
Academic Article The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.
Academic Article Does the route of feeding modify the inflammatory response?
Academic Article Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones.
Academic Article Circulating interleukin-1 receptor antagonist concentrations are increased in adult patients with thermal injury.
Academic Article Balance of synovial fluid IL-1 beta and IL-1 receptor antagonist and recovery from Lyme arthritis.
Academic Article Are events after endotoxemia related to circulating phospholipase A2?
Academic Article Induction of circulating antagonists to IL-1 and TNF by IL-2 administration and their effects on IL-2 induced cytokine production in vitro.
Academic Article Interleukin-1.
Academic Article Circulating interleukin-1 and tumor necrosis factor antagonists in liver disease.
Academic Article Pyrogenic properties of bleomycin (NSC-125066).
Academic Article Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases.
Academic Article Gender differences in IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist secretion from mononuclear cells and urinary excretion.
Academic Article Modalities for reducing interleukin 1 activity in disease.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.
Academic Article Ciliary neurotrophic factor is an endogenous pyrogen.
Academic Article Induction of circulating and erythrocyte-bound IL-8 by IL-2 immunotherapy and suppression of its in vitro production by IL-1 receptor antagonist and soluble tumor necrosis factor receptor (p75) chimera.
Academic Article Fever produced in the squirrel monkey by human leukocytic pyrogen.
Academic Article Demonstration and characterization of two distinct human leukocytic pyrogens.
Academic Article Interleukin-1 and tumor necrosis factor and their naturally occurring antagonists during hemodialysis.
Academic Article The role of interleukin-1 in host responses to infectious diseases.
Academic Article The role of interleukin-1 in disease.
Academic Article Anticytokine strategies in the treatment of the systemic inflammatory response syndrome.
Academic Article Induction of circulating IL-1 receptor antagonist by IFN treatment.
Academic Article Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1.
Academic Article Detection of tumor necrosis factor soluble receptor p55 in blood samples from healthy and endotoxemic humans.
Academic Article Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein.
Academic Article The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice.
Academic Article Interleukin-1 receptor antagonist inhibits subcutaneous B16 melanoma growth in vivo.
Academic Article Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells.
Academic Article A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis.
Academic Article Plasma cytokines, cytokine antagonists, and disease progression in African women infected with HIV-1.
Academic Article Expression of interleukin-1 receptor antagonist (IL-1ra) by human circulating polymorphonuclear cells.
Academic Article Role of interleukin 1 in antigen-specific T cell proliferation.
Academic Article Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.
Academic Article Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors.
Academic Article Controlling the production of interleukin-1 and tumor necrosis factor in disease.
Academic Article Induction of circulating interleukin 10 by interleukin 1 and interleukin 2, but not interleukin 6 immunotherapy.
Academic Article Cytokines as mediators in the pathogenesis of septic shock.
Academic Article Thermoregulation and the pathogenesis of fever.
Academic Article Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis.
Academic Article Langerhans cell production of interleukin-1.
Academic Article Mechanism of action of cyclosporin A. Effect on T-cell-binding of interleukin 1 and antagonizing effect of insulin.
Academic Article Circulating interleukin-1 beta and tumor necrosis factor-alpha concentrations after burn injury in humans.
Academic Article Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.
Academic Article Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever.
Academic Article [Demonstration of a bacterial structure in two human mediators: a sleep facilitating factor and a monokine].
Academic Article Reduction of inflammation by decreasing production of interleukin-1 or by specific receptor antagonism.
Academic Article Granulocyte-macrophage colony-stimulating factor synthesis during experimental endotoxemia in humans.
Academic Article Interleukin-1 and interleukin-1 receptor antagonist.
Academic Article Three distinct promoters direct transcription of different 5' untranslated regions of the human interleukin 1 type I receptor: a possible mechanism for control of translation.
Academic Article Hyperosmotic stress as a stimulant for proinflammatory cytokine production.
Academic Article Mechanisms of loss of lean body mass in patients on chronic dialysis.
Academic Article Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells.
Academic Article The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity.
Academic Article The natural interleukin-1 receptor antagonist in term and preterm parturition.
Academic Article IL-6 and APPs: anti-inflammatory and immunosuppressive mediators.
Academic Article Blocking interleukin-1 and tumor necrosis factor in disease.
Academic Article Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans.
Academic Article Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays.
Academic Article Studies on the active site of human leukocytic pyrogen.
Academic Article Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells.
Academic Article Ability of human leukocytic pyrogen to stimulate brain prostaglandin synthesis in vitro.
Academic Article Correlation of serum levels of interleukin-1 family members with disease activity and response to treatment in hairy cell leukemia.
Academic Article Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells.
Academic Article Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.
Academic Article Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.
Academic Article Introduction: surviving septic shock.
Academic Article Modulation of acute myeloblastic leukemia (AML) cell proliferation and blast colony formation by antisense oligomer for IL-1 beta converting enzyme (ICE) and IL-1 receptor antagonist (IL-1ra).
Academic Article The association of peripheral monocyte derived interleukin 1beta (IL-1beta), IL-1 receptor antagonist, and tumor necrosis factor-alpha with osteoarthritis in the elderly.
Academic Article [Antagonists in neonatal sepsis].
Academic Article Recent advances in cytokines, cytokine receptors and signal transduction.
Academic Article Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings.
Academic Article To Sheldon M. Wolff, as we commemorate the 10th anniversary of the clonings of IL-1 alpha and IL-1 beta.
Academic Article The biological properties of interleukin-1.
Academic Article A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses.
Academic Article Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans.
Academic Article IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family.
Academic Article Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme.
Academic Article Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes.
Academic Article Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes.
Academic Article Dissociation of transcription from translation of human IL-1 beta: induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Monokine antagonism is reduced in patients with IDDM.
Academic Article Role of interleukin-1 in infectious diseases.
Academic Article Interleukin 18 stimulates HIV type 1 in monocytic cells.
Academic Article Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures.
Academic Article Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function.
Academic Article Interleukin-18.
Academic Article The biology of interleukin-1.
Academic Article Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).
Academic Article Circulating leptin during experimental endotoxemia in humans.
Academic Article Elevated circulating levels of soluble interleukin-1 receptor type II during interleukin-2 immunotherapy.
Academic Article Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus.
Academic Article Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.
Academic Article Blocking interleukin-1 in disease.
Academic Article Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55.
Academic Article Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.
Academic Article Immunologic effects of national cholesterol education panel step-2 diets with and without fish-derived N-3 fatty acid enrichment.
Academic Article Linkage disequilibrium testing of four interleukin-1 gene-cluster polymorphisms in Danish multiplex families with insulin-dependent diabetes mellitus.
Academic Article IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.
Academic Article Modulation of cell proliferation and cytokine production in AML by recombinant interleukin-1 receptor antagonist.
Academic Article Is there an interleukin-1 genetic predisposition to developing severe sepsis?
Academic Article Anti-cytokine strategies.
Academic Article Modalities for reducing interleukin 1 activity in disease.
Academic Article Elaboration of interleukin 1-receptor antagonist is not attenuated by glucocorticoids after endotoxemia.
Academic Article Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event.
Academic Article Acellular components of Chlamydia pneumoniae stimulate cytokine production in human blood mononuclear cells.
Academic Article The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense.
Academic Article Angiotensin-converting-enzyme inhibitors suppress synthesis of tumour necrosis factor and interleukin 1 by human peripheral blood mononuclear cells.
Academic Article Osmotic regulation of cytokine synthesis in vitro.
Academic Article Biologic basis for interleukin-1 in disease.
Academic Article Protein metabolism in rheumatoid arthritis and aging. Effects of muscle strength training and tumor necrosis factor alpha.
Academic Article Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain.
Academic Article Proinflammatory cytokines in heart disease.
Academic Article The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1.
Academic Article Tumor necrosis factor (TNF)-alpha-induced interleukin-8 in human blood cultures discriminates neutralization by the p55 and p75 TNF soluble receptors.
Academic Article Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells.
Academic Article Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist.
Academic Article Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases.
Academic Article An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding.
Academic Article The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment.
Academic Article Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18.
Academic Article Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma.
Academic Article Identification of amino acid residues critical for biological activity in human interleukin-18.
Academic Article Novel targets for interleukin 18 binding protein.
Academic Article IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
Academic Article The pattern of interleukin-1beta (IL-1beta) and its modulating agents IL-1 receptor antagonist and IL-1 soluble receptor type II in acute meningococcal infections.
Academic Article Interleukin-18 binding protein in acute graft versus host disease and engraftment following allogeneic peripheral blood stem cell transplants.
Academic Article Anti-cytokine therapies in response to systemic infection.
Academic Article Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.
Academic Article Rat interleukin-18 binding protein: cloning, expression, and characterization.
Academic Article Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1 beta activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein.
Academic Article Interferon-alpha induces interleukin-18 binding protein in chronic hepatitis C patients.
Academic Article A surface amebic cysteine proteinase inactivates interleukin-18.
Academic Article Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells.
Academic Article Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study.
Academic Article Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.
Academic Article Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro.
Academic Article Taurolidine, an analogue of the amino acid taurine, suppresses interleukin 1 and tumor necrosis factor synthesis in human peripheral blood mononuclear cells.
Academic Article Interleukin-18 and host defense against infection.
Academic Article Effect of oral n-3 fatty acid supplementation on the immune response of young and older women.
Academic Article Setting the cytokine trap for autoimmunity.
Academic Article Adjunctive therapy with intravenous human immunoglobulin G improves survival of patients with acute renal failure.
Academic Article Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells.
Academic Article Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells.
Academic Article Transcription, translation and secretion of interleukin 1 and tumor necrosis factor: effects of tebufelone, a dual cyclooxygenase/5-lipoxygenase inhibitor.
Academic Article Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study.
Academic Article Anti-cytokine therapeutics and infections.
Academic Article Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex.
Academic Article Fever: links with an ancient receptor.
Academic Article Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease.
Academic Article Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells.
Academic Article Interleukin-1 and interleukin-1 antagonism.
Academic Article The IL-1 family and inflammatory diseases.
Academic Article Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.
Academic Article Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro.
Academic Article The specific IL-1 inhibitor from the human M20 cell line is distinct from the IL-1 receptor antagonist.
Academic Article Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria.
Academic Article Biology of tumor necrosis factor-alpha- implications for psoriasis.
Academic Article Interleukin-18 and the treatment of rheumatoid arthritis.
Academic Article Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.
Academic Article Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
Academic Article Mutation scan of a type 1 diabetes candidate gene: the human interleukin-18 binding protein gene.
Academic Article Interleukin-1 is a mucus secretagogue.
Academic Article Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed.
Academic Article Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response.
Academic Article TNF-alpha mediates obstruction-induced renal tubular cell apoptosis and proapoptotic signaling.
Academic Article Cytokines as potential therapeutic targets for inflammatory skin diseases.
Academic Article Interleukin-18 does not modulate the acute-phase response.
Academic Article IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response.
Academic Article p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function.
Academic Article Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events.
Academic Article Blocking IL-1 in systemic inflammation.
Academic Article Rapid responses to anakinra in patients with refractory adult-onset Still's disease.
Academic Article IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Academic Article An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor.
Academic Article Inhibitors of histone deacetylases as anti-inflammatory drugs.
Academic Article A pilot study of cytokine levels and white blood cell counts in the diagnosis of necrotizing fasciitis.
Academic Article Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules.
Academic Article Peripheral blood neutrophil activation patterns are associated with pulmonary inflammatory responses to lipopolysaccharide in humans.
Academic Article Proteinase 3 is an IL-32 binding protein.
Academic Article Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.
Academic Article The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo.
Academic Article Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells.
Academic Article Immunoregulatory functions of paf-acether. IV. Enhancement of IL-1 production by muramyl dipeptide-stimulated monocytes.
Academic Article The paradox of pro-inflammatory cytokines in cancer.
Academic Article Dissociation of immunoregulatory function of blood monocytes from maturational state and expression of interleukin-1 in humans chronically infected with Schistosoma mansoni.
Academic Article Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2.
Academic Article IL-32, a novel cytokine with a possible role in disease.
Academic Article The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity.
Academic Article Effect of a four-week course of interleukin-10 on cytokine production in a placebo-controlled study of HIV-1-infected subjects.
Academic Article Interleukin-1, anorexia, and dietary fatty acids.
Academic Article Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911.
Academic Article Differential effects of anti-IL-1R accessory protein antibodies on IL-1alpha or IL-1beta-induced production of PGE(2) and IL-6 from 3T3-L1 cells.
Academic Article Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1).
Academic Article The pathophysiology of the pro-inflammatory cytokines.
Academic Article Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis.
Academic Article Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level.
Academic Article Neonatal interleukin-1 beta, interleukin-6, and tumor necrosis factor: cord blood levels and cellular production.
Academic Article The pyrogenicity of the synthetic adjuvant muramyl dipeptide and two structural analogues.
Academic Article The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
Academic Article Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF.
Academic Article Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells.
Academic Article Dissociation between interleukin-1 beta mRNA and protein synthesis in human peripheral blood mononuclear cells.
Academic Article Resistant Beh?et disease responsive to anakinra.
Academic Article Proteinase 3-processed form of the recombinant IL-32 separate domain.
Academic Article Interleukin-18 binding protein transgenic mice are protected against ischemic acute kidney injury.
Academic Article Identification of the most active interleukin-32 isoform.
Academic Article Targeting the pathogenic role of interleukin 1{beta} in the progression of smoldering/indolent myeloma to active disease.
Academic Article Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood.
Academic Article Modulation of muramyl dipeptide stimulation of cytokine production by blood components.
Academic Article Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.
Academic Article Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.
Academic Article Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro.
Academic Article Interleukin-1: multiple biological properties and mechanisms of action.
Academic Article IL-18 activity in systemic lupus erythematosus.
Academic Article Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils.
Academic Article New concepts on the pathogenesis of fever.
Academic Article Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta.
Academic Article Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.
Academic Article IL-1 production by T6 (CD1a) positive cord blood mononuclear cells (Langerhan's cell precursors?).
Academic Article Cytokine gene expression and synthesis by human megakaryocytic cells.
Academic Article IL-1: discoveries, controversies and future directions.
Academic Article Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta.
Academic Article Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis.
Academic Article Anti-inflammatory Agents: Present and Future.
Academic Article IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2.
Academic Article The endogenous pyrogens in host-defense interactions.
Academic Article Interleukin-1 and the effects of cyclooxygenase inhibitors on its biological activities.
Academic Article Role of IL-1beta in type 2 diabetes.
Academic Article Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3.
Academic Article Cytokines: agents provocateurs in hemodialysis?
Academic Article Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation.
Academic Article Adult-onset Still's disease with myocarditis successfully treated with the interleukin-1 receptor antagonist anakinra.
Academic Article Blocking interleukin-1? in acute and chronic autoinflammatory diseases.
Academic Article Serum and urinary levels of IL-18 and its inhibitor IL-18BP in systemic lupus erythematosus.
Academic Article Synergy of helper factors in the differentiation of in vivo-preactivated antigen-specific human B cells.
Academic Article Proinflammatory cytokines.
Academic Article Protection from RNA and DNA viruses by IL-32.
Academic Article Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir.
Academic Article A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures.
Academic Article Induction by IL 1 and interferon-?: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254.
Academic Article Anakinra for the inflammatory complications of chronic granulomatous disease.
Academic Article A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone.
Academic Article IL-1 induction-capacity of defined lipopolysaccharide partial structures.
Academic Article Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancer.
Academic Article Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury.
Academic Article Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta.
Academic Article Interleukin-1 and the response to injury.
Academic Article Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.
Academic Article [Cytokines in the pathogenesis of fever].
Academic Article Tumour necrosis factor production in Falciparum malaria and its association with schizont rupture.
Academic Article Interleukin 37 expression protects mice from colitis.
Academic Article Inhibition of IL-32 activation by a-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
Academic Article IL-1a and IL-1? recruit different myeloid cells and promote different stages of sterile inflammation.
Academic Article Interplay between redox status and inflammasome activation.
Academic Article Production of interleukin-1-receptor antagonist during experimental endotoxaemia.
Academic Article IL-37: a new anti-inflammatory cytokine of the IL-1 family.
Academic Article IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.
Academic Article Interleukin-1?-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Behcet's disease: an open-label pilot study.
Academic Article Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1a.
Academic Article The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
Academic Article Interleukin 32 (IL-32) contains a typical a-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.
Academic Article IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Academic Article Interleukin-1 and inhibition of interleukin-1 in hemodialysis patients.
Academic Article IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.
Academic Article Interleukin-1 stimulates prostaglandin biosynthesis by human amnion.
Academic Article Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.
Academic Article Membrane interleukin-18 revisits membrane IL-1a in T-helper type 1 responses.
Academic Article Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes.
Academic Article Interleukin-32: a predominantly intracellular proinflammatory mediator that controls cell activation and cell death.
Academic Article Neutrophil-mediated inhibition of proinflammatory cytokine responses.
Academic Article The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses.
Academic Article A peptide from alveolar macrophages that releases neutrophil enzymes into the lungs in patients with the adult respiratory distress syndrome.
Academic Article Role of IL-18 in second-hand smoke-induced emphysema.
Academic Article Enhancement of in-vitro human interleukin-1 production by sodium acetate.
Academic Article Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.
Academic Article IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor.
Academic Article The role of interleukin 1 (IL 1) in tumor-NK cell interactions: correction of defective NK cell activity in cancer patients by treating target cells with IL 1.
Academic Article Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans.
Academic Article Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones.
Academic Article Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils.
Academic Article Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).
Academic Article Multiple biological properties of recombinant human interleukin 1 (beta).
Academic Article Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin).
Academic Article Ultrafiltration to reject human interleukin-1-inducing substances derived from bacterial cultures.
Academic Article Interleukin-1 in the pathogenesis of fever.
Academic Article Biological consequences of monocyte activation during hemodialysis.
Academic Article Chemical characterization of an interleukin-1-inducing substance derived from human mixed leukocyte reactions: IL-1-inducing substance is not gamma interferon.
Academic Article Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.
Academic Article Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF.
Academic Article Studies on the ability of hemodialysis membranes to induce, bind, and clear human interleukin-1.
Academic Article Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type.
Academic Article Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells.
Academic Article Recombinant interleukin 1 and tumor necrosis factor acting in synergy to release thromboxane, 6-KETO-PGF1 alpha and PGE2 by human neutrophils.
Academic Article The Jeremiah Metzger Lecture. The pathogenesis of fever in human subjects.
Academic Article Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1.
Academic Article Prostaglandins posttranscriptionally inhibit monocyte expression of interleukin 1 activity by increasing intracellular cyclic adenosine monophosphate.
Academic Article Detection of endotoxin-like interleukin-1-inducing activity during in vitro dialysis.
Academic Article Interleukin-1 and biocompatibility in haemodialysis.
Academic Article Interleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas.
Academic Article Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans.
Academic Article Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.
Academic Article Interleukin-1 stimulation in the ESRD patient: potential long-term consequences.
Academic Article Interleukin-1.
Academic Article IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma.
Academic Article Restoration of anti-interleukin-1 depressed natural killer activity by human recombinant interferon alpha or gamma, human recombinant interleukin-2 and indomethacin.
Academic Article Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.
Academic Article Induction of interleukin 1 by synthetic and naturally occurring muramyl peptides.
Academic Article Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro.
Academic Article Interleukin-1: the pros and cons of its clinical relevance.
Academic Article C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha.
Academic Article Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients.
Academic Article Endogenous pyrogens.
Academic Article Plasma interleukin-1 activity during hemodialysis: the influence of dialysis membranes.
Academic Article Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.
Academic Article The multiple biological properties of interleukin-1 influencing immunocompetent cells.
Academic Article The relationship between biocompatibility and interleukin-1.
Academic Article Interleukins.
Academic Article Interleukin-1--its multiple biological effects and its association with hemodialysis.
Academic Article The role of interferon-beta 1 and the 26-kDa protein (interferon-beta 2) as mediators of the antiviral effect of interleukin 1 and tumor necrosis factor.
Academic Article Induction of tumor necrosis factor during extracorporeal blood purification.
Academic Article Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.
Academic Article Effect of protein synthesis inhibitors on leukocytic pyrogen-induced in vitro hypothalamic prostaglandin production.
Academic Article Dissimilarities between purified human interleukin-1 and recombinant human interleukin-2 in the induction of fever, brain prostaglandin, and acute-phase protein synthesis.
Academic Article Human and murine interleukin 1 possess sequence and structural similarities.
Academic Article Purification and characterization of a unique human interleukin 1 from the tumor cell line U937.
Academic Article Fish lymphocytes respond to human IL-1.
Academic Article Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid.
Academic Article Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells.
Academic Article In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1.
Academic Article Human thymic epithelial cells produce interleukin 1.
Academic Article Plasma interleukin-1 activity in humans undergoing hemodialysis with regenerated cellulosic membranes.
Academic Article Effects of human interleukin 1 and human tumor necrosis factor on human T lymphocyte colony formation.
Academic Article Development and use of a radioimmunoassay for human interleukin-1 beta.
Academic Article Interleukin 1 production by human lung tissue. I. Identification and characterization.
Academic Article Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans.
Academic Article Self-regulation of procoagulant events on the endothelial cell surface.
Academic Article A switch to high-flux helixone membranes reverses suppressed interferon-gamma production in patients on low-flux dialysis.
Academic Article Interleukin-1 and the pathogenesis of the acute-phase response.
Academic Article Effect of ibuprofen on fever and metabolic changes induced by continuous infusion of leukocytic pyrogen (interleukin 1) or endotoxin.
Academic Article Interleukin-1.
Academic Article Demonstration of a human pyrogen-inducing factor during mixed leukocyte reactions.
Academic Article Interleukin 1 as mediator of the acute-phase response.
Academic Article Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.
Academic Article The biology of SAA: identification of the inducer, in vitro synthesis, and heterogeneity demonstrated with monoclonal antibodies.
Academic Article Reduced mitogen stimulation of DNA synthesis in human lymphocytes by a human recombinant interleukin-1 receptor antagonist.
Academic Article Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor.
Academic Article Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated.
Academic Article Production of leukocytic pyrogen from phagocytes of neonates.
Academic Article Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen.
Academic Article Interleukin-1 and interleukin-1 receptor antagonist production during haemodialysis: which cytokine is a surrogate marker for dialysis-related complications?
Academic Article IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease.
Academic Article Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure.
Academic Article Is there a role for interleukin-1 blockade in intravenous immunoglobulin therapy?
Academic Article Interleukin-1 receptor antagonist: an index of dialysis-induced interleukin-1 production.
Academic Article Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism.
Academic Article Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone.
Academic Article The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription.
Academic Article The interleukin-1 family: 10 years of discovery.
Academic Article Production of cytokines and cytokine inhibitory proteins in patients on dialysis.
Academic Article Administration of low-dose endotoxin to healthy humans increases C5a binding to circulating neutrophils.
Academic Article Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds.
Academic Article Plasma levels of IL-1 beta, TNF alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients.
Academic Article Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation.
Academic Article Dietary supplementation with n-3 fatty acids suppresses interleukin-2 production and mononuclear cell proliferation.
Academic Article Suppression of juvenile chronic myelogenous leukemia colony growth by interleukin-1 receptor antagonist.
Academic Article Comparison of first use and reuse of cuprophan membranes on interleukin-1 receptor antagonist and interleukin-1 beta production by blood mononuclear cells.
Academic Article A method for the detection of erythrocyte-bound interleukin-8 in humans during interleukin-1 immunotherapy.
Academic Article Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats.
Academic Article Gene expression of interleukin-1 beta during hemodialysis.
Academic Article Identification of the promoter region of human interleukin 1 type I receptor gene: multiple initiation sites, high G+C content, and constitutive expression.
Academic Article Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.
Academic Article Characterization of polymorphisms of an interleukin 1 receptor type 1 gene (IL1RI) promotor region (P2) and their relation to insulin-dependent diabetes mellitus (IDDM). The Danish Study Group of Diabetes in Childhood.
Academic Article Soluble tumor necrosis factor receptors inhibit phorbol myristate acetate and cytokine-induced HIV-1 expression chronically infected U1 cells.
Academic Article IL-6 and IL-8 production from cultured human endothelial cells stimulated by infection with Rickettsia conorii via a cell-associated IL-1 alpha-dependent pathway.
Academic Article Oral aspirin and ibuprofen increase cytokine-induced synthesis of IL-1 beta and of tumour necrosis factor-alpha ex vivo.
Academic Article High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis.
Academic Article Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress.
Academic Article Clinical, hematologic, and immunologic effects of interleukin-10 in humans.
Academic Article Lipopolysaccharide induces human interleukin-1 receptor antagonist and interleukin-1 production in the same cell.
Academic Article Transfer of cytokine-inducing bacterial products across hemodialyzer membranes in the presence of plasma or whole blood.
Academic Article Interleukin-1 alpha and interleukin-1 beta in preterm and term human parturition.
Academic Article Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-alpha-independent IL-8 secretion and E-selectin expression.
Academic Article Induction of interleukin-1 and interleukin-1 receptor antagonist.
Academic Article Fever.
Academic Article Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
Academic Article The many worlds of reducing interleukin-1.
Academic Article Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome.
Academic Article Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock.
Academic Article Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood.
Academic Article Monocyte cytokine production in an elderly population: effect of age and inflammation.
Academic Article In vitro production of interleukin-1 receptor antagonist in chronic renal failure, CAPD and HD.
Academic Article Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women.
Academic Article Interleukin-1.
Academic Article Overview of interleukin-18: more than an interferon-gamma inducing factor.
Academic Article Elevated levels of soluble interleukin-1 receptor type II and interleukin-1 receptor antagonist in patients with chronic arthritis: correlations with markers of inflammation and joint destruction.
Academic Article Adenosine reduces cardiac TNF-alpha production and human myocardial injury following ischemia-reperfusion.
Academic Article New polyether sulfone dialyzers attenuate passage of cytokine-inducing substances from pseudomonas aeruginosa contaminated dialysate.
Academic Article Human myocardial tissue TNFalpha expression following acute global ischemia in vivo.
Academic Article Spontaneous and inducible cytokine responses in healthy humans receiving a single dose of IFN-alpha2b: increased production of interleukin-1 receptor antagonist and suppression of IL-1-induced IL-8.
Academic Article Phase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera.
Academic Article Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Academic Article Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells.
Academic Article Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.
Academic Article Cytokines as endogenous pyrogens.
Academic Article Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression.
Academic Article Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process.
Academic Article Histone hyperacetylation is associated with amelioration of experimental colitis in mice.
Academic Article Modulatory in vitro effects of interleukin-1 receptor antagonist (IL-1Ra) or antisense oligonucleotide to interleukin-1 beta converting enzyme (ICE) on acute myeloid leukaemia (AML) cell growth.
Academic Article Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen.
Academic Article Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy.
Academic Article Oxidation of low-density lipoproteins by acellular components of Chlamydia pneumoniae.
Academic Article Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Academic Article IL-1 induces IL-1. IV. IFN-gamma suppresses IL-1 but not lipopolysaccharide-induced transcription of IL-1.
Academic Article Targeting interleukin 18 with interleukin 18 binding protein.
Academic Article Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors.
Academic Article Soluble human p55 and p75 tumor necrosis factor receptors reverse spontaneous arthritis in transgenic mice expressing transmembrane tumor necrosis factor alpha.
Academic Article Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression.
Academic Article Differential roles of interleukin-18 (IL-18) and IL12 for induction of gamma interferon by staphylococcal cell wall components and superantigens.
Academic Article Tumor necrosis factor-alpha, interleukin-1, and interferon alpha stimulate triglyceride synthesis in HepG2 cells.
Academic Article Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels.
Academic Article IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
Academic Article The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures.
Academic Article Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Academic Article Interleukin-18 binding protein reduces b16 melanoma hepatic metastasis by neutralizing adhesiveness and growth factors of sinusoidal endothelium.
Academic Article IL-1 is required for tumor invasiveness and angiogenesis.
Academic Article Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure.
Academic Article Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity?
Academic Article Generation and characterization of mice transgenic for human IL-18-binding protein isoform a.
Academic Article Atherogenic effects of Chlamydia pneumoniae: refuting the innocent bystander hypothesis.
Academic Article Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
Academic Article Unraveling the NALP-3/IL-1beta inflammasome: a big lesson from a small mutation.
Academic Article Differences in signaling pathways by IL-1beta and IL-18.
Academic Article Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation.
Academic Article Imbalance between interleukin-1 agonists and antagonists: relationship to severity of inflammatory bowel disease.
Academic Article Antiviral and immunoregulatory activities of IFN-gamma depend on constitutively expressed IL-1alpha.
Academic Article Cytokines and biocompatibility.
Academic Article Interleukin-32: a cytokine and inducer of TNFalpha.
Academic Article Elevated systemic levels of free interleukin-18 (IL-18) in patients with Crohn's disease.
Academic Article A signal for the caspase-1 inflammasome free of TLR.
Academic Article Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle.
Academic Article Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha.
Academic Article IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Academic Article Interleukin-1beta.
Academic Article The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome.
Academic Article Effects of omega 3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. Comparison with oral aspirin and ibuprofen.
Academic Article Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6.
Academic Article The effect of whole body hyperthermia on the immune cell activity of cancer patients.
Academic Article Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits.
Academic Article Interleukin-1 is released at sites of human cutaneous allergic reactions.
Academic Article Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
Academic Article Interleukin-32 induces the differentiation of monocytes into macrophage-like cells.
Academic Article Measurement of soluble and membrane-bound interleukin 1 using a fibroblast bioassay.
Academic Article Transcription, not synthesis, of interleukin-1 and tumor necrosis factor by complement.
Academic Article Endogenous IL-32 controls cytokine and HIV-1 production.
Academic Article Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice.
Academic Article Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Academic Article Inflammation in human disease: anticytokine therapy.
Academic Article IL-32-dependent effects of IL-1beta on endothelial cell functions.
Academic Article Inhibitory effects of elevated temperature on human cytokine production and natural killer activity.
Academic Article NIH conference. Immunomodulators in clinical medicine.
Academic Article High circulating levels of free interleukin-18 in patients with active SLE in the presence of elevated levels of interleukin-18 binding protein.
Academic Article Interleukin-18 and the pathogenesis of inflammatory diseases.
Academic Article IL-18 in autoimmunity: review.
Academic Article Inflammatory markers and the risk of Alzheimer disease: the Framingham Study.
Academic Article Low-flux hemodialysis suppresses interferon-gamma production: the possible role of beta2-microglobulin.
Academic Article IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.
Academic Article Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
Academic Article Dissociation of transcription from translation of human IL-1-beta: the induction of steady state mRNA by adherence or recombinant C5a in the absence of translation.
Academic Article Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself.
Academic Article Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity.
Academic Article Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factor.
Academic Article Leukocyte endogenous mediator fails to alter protein dynamics in a model of liver dysfunction.
Academic Article Interleukin-1 and its biologically related cytokines.
Academic Article Historical insights into cytokines.
Academic Article Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.
Academic Article Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
Academic Article Interleukin-1 induces a shock-like state in rabbits: synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition.
Academic Article The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro.
Academic Article Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.
Academic Article Interleukin-1 beta in human colostrum.
Academic Article Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).
Academic Article Interleukin 1 suppresses inflammation in rabbit colitis. Mediation by endogenous prostaglandins.
Academic Article Interleukin-18 binding protein in the sera of patients with Wegener's granulomatosis.
Academic Article Impaired counter-regulation of interleukin-1 by the soluble IL-1 receptor type II in patients with chronic liver disease.
Academic Article IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease.
Academic Article Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines.
Academic Article IL-1 family nomenclature.
Academic Article Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
Academic Article alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice.
Academic Article Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality.
Academic Article Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.
Academic Article Immunological and inflammatory functions of the interleukin-1 family.
Academic Article A histamine-releasing factor from activated human mononuclear cells.
Academic Article Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.
Academic Article Interleukin-1beta and the autoinflammatory diseases.
Academic Article Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
Academic Article Hyperosmolar sodium chloride, p38 mitogen activated protein and cytokine-mediated inflammation.
Academic Article Circulating lymphokine levels in the chronic fatigue syndrome.
Academic Article Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells.
Academic Article Lymphokines.
Academic Article Tumor necrosis factor and endotoxin induce similar metabolic responses in human beings.
Academic Article TREM-1 interaction with the LPS/TLR4 receptor complex.
Academic Article IL-32 is a host protective cytokine against Mycobacterium tuberculosis in differentiated THP-1 human macrophages.
Academic Article Plasmapheresis for fulminant meningococcemia.
Academic Article Why not treat human cancer with interleukin-1 blockade?
Academic Article In vitro production of IL 1 beta, IL 1 alpha, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation.
Academic Article The interleukin 1 receptor.
Academic Article Differential effects of interleukin-1 alpha and interleukin-1 beta on human peripheral blood eosinophils.
Academic Article IL-37 is a fundamental inhibitor of innate immunity.
Academic Article Paradoxical effects of constitutive human IL-32{gamma} in transgenic mice during experimental colitis.
Academic Article A clinical perspective of IL-1? as the gatekeeper of inflammation.
Academic Article Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis.
Academic Article More than inflammation: interleukin-1beta polymorphisms and the lipid metabolism.
Academic Article Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade.
Academic Article Interleukin-1 in the pathogenesis and treatment of inflammatory diseases.
Academic Article Inflammasome activation and IL-1? and IL-18 processing during infection.
Academic Article Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).
Academic Article Interleukin-32: a new proinflammatory cytokine involved in hepatitis C virus-related liver inflammation and fibrosis.
Academic Article The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering.
Academic Article Interleukin-1 in the pathogenesis of and protection from inflammatory bowel disease.
Academic Article Induction of interleukin-1 and tumor necrosis factor during in vitro hemodialysis with different membranes.
Academic Article Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1.
Academic Article Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells.
Academic Article Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children.
Academic Article Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases.
Academic Article NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1? processing via the NLRP1 inflammasome.
Academic Article Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study].
Academic Article Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism.
Academic Article The lysine deacetylase inhibitor Givinostat inhibits ?-cell IL-1? induced IL-1? transcription and processing.
Academic Article Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1.
Academic Article Release of lymphokines after infection with Epstein Barr virus in vitro. II. A monocyte-dependent inhibitor of interleukin 1 downregulates the production of interleukin 2 and interferon-gamma in rheumatoid arthritis.
Academic Article Regulation of class III major histocompatibility complex gene products by interleukin-1.
Academic Article The production of antibody against human leukocytic pyrogen.
Academic Article Interaction of IL 1 and TPA in modulation of eosinophil function.
Academic Article Human monocyte or recombinant interleukin 1's are specific for the secretion of a metalloproteinase from chondrocytes.
Academic Article C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma.
Academic Article The effect of interleukin 1 on IgG synthesis in systemic lupus erythematosus.
Academic Article Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
Academic Article Interleukin-1 beta in human plasma: optimization of blood collection, plasma extraction, and radioimmunoassay methods.
Academic Article Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling.
Academic Article Interleukin-1 and its relevance in patients treated with hemodialysis.
Academic Article Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity.
Academic Article Studies on the biological properties of purified and recombinant human interleukin-1.
Academic Article Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing?
Academic Article Metabolic changes following eccentric exercise in trained and untrained men.
Academic Article Inducible interleukin-1 gene expression in human vascular smooth muscle cells.
Academic Article Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium.
Academic Article Studies on the molecular nature of human interleukin 1.
Academic Article Role of interleukin-1 in augmenting serum neutralization of bacterial lipopolysaccharide.
Academic Article Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans.
Academic Article Modulation of endothelial cell functions by different molecular species of interleukin 1.
Academic Article Increased plasma interleukin-1 activity in women after ovulation.
Academic Article CAPD is a second-class treatment.
Academic Article Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol.
Academic Article Increased interleukin 1 beta in human skeletal muscle after exercise.
Academic Article Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps.
Academic Article Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation.
Academic Article Innate immune response of human alveolar macrophages during influenza A infection.
Academic Article Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure.
Academic Article Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis.
Academic Article A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia.
Academic Article Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.
Academic Article Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells.
Academic Article Detection of circulating tumor necrosis factor after endotoxin administration.
Academic Article Effect of recombinant a1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes.
Academic Article Interleukin-1 is a chemotactic factor for human T-lymphocytes.
Academic Article Interleukin-1.
Academic Article Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain.
Academic Article Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.
Academic Article Interleukin-1 and dialysis.
Academic Article The biology of interleukin 1 and comparison to tumor necrosis factor.
Academic Article Interleukin-1 induces natriuresis in conscious rats: role of renal prostaglandins.
Academic Article Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits.
Academic Article Recombinant human interleukin-1 beta causes histamine release from human basophils.
Academic Article A radioimmunoassay for human interleukin-1 alpha: measurement of IL-1 alpha produced in vitro by human blood mononuclear cells stimulated with endotoxin.
Academic Article Interleukin-1 enhances pain reflexes. Mediation through increased prostaglandin E2 levels.
Academic Article Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.
Academic Article Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.
Academic Article Induction of interleukin-1 during CAPD.
Academic Article Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.
Academic Article Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.
Academic Article Human interleukin-1 production during hemodialysis.
Academic Article Physiological mechanisms contributing to increased interleukin-1 secretion.
Academic Article Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line.
Academic Article A new micromethod for determination of interleukin-1 production from frozen human blood mononuclear cells.
Academic Article Ventricular fluid interleukin-1 activity in patients with head injury.
Academic Article Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1.
Academic Article Multiple biological activities of human recombinant interleukin 1.
Academic Article Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.
Academic Article Differential effects of human interleukin-1 on growth of human fibroblasts and vascular smooth muscle cells.
Academic Article Parasite-monocyte interactions in human leishmaniasis: production of interleukin-1 in vitro.
Academic Article Intracellular human IL-1: a precursor for the secreted monokine.
Concept Humans
Concept Human Growth Hormone
Concept Human Genome Project
Concept Herpesvirus 2, Human
Concept Human papillomavirus 16
Concept Chromosomes, Human, Pair 11
Concept Genome, Human
Concept Influenza, Human
Concept Hepatitis, Viral, Human
Concept Chromosomes, Human, Pair 2
Concept Herpesvirus 4, Human
Academic Article A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma.
Academic Article Alpha-1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis.
Academic Article Towards a role of interleukin-32 in atherosclerosis.
Academic Article Anti-inflammatory and immunomodulatory properties of a1-antitrypsin without inhibition of elastase.
Academic Article The C3a receptor, caspase-1, and release of IL-1?.
Academic Article Effects of interleukin-1 blockade with anakinra on aerobic exercise capacity in patients with heart failure and preserved ejection fraction (from the D-HART pilot study).
Academic Article The interleukin-1 family: back to the future.
Academic Article IL-32 promotes angiogenesis.
Academic Article Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation.
Academic Article Novel insights into the biology of interleukin-32.
Academic Article Treating inflammation by blocking interleukin-1 in humans.
Academic Article Interleukin-37.
Academic Article Overview of the interleukin-1 family of ligands and receptors.
Academic Article Interleukin-1? in innate inflammation, autophagy and immunity.
Academic Article Interleukin-18, more than a Th1 cytokine.
Academic Article Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and ?-cell protection.
Academic Article Interleukin-1 blockade in rheumatoid arthritis and heart failure: a missed opportunity?
Academic Article Comment on "Power of rare diseases: found in translation".
Academic Article Interleukin-10 in patients with ST-segment elevation myocardial infarction.
Academic Article Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Academic Article Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.
Academic Article IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.
Academic Article A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist.
Academic Article Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial.
Academic Article Interleukin-1a neutralisation in patients with cancer.
Academic Article Acute-phase protein a1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion.
Academic Article Deficient autophagy unravels the ROS paradox in chronic granulomatous disease.
Academic Article a1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1? responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.
Academic Article Interleukin-1 affects the function of cultured human thyroid cells.
Academic Article IL-37 protects against obesity-induced inflammation and insulin resistance.
Academic Article a-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics.
Academic Article Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells.
Academic Article Clinical predictors of response to anakinra in patients with heart failure.
Academic Article Effects of Prolastin C (Plasma-Derived Alpha-1 Antitrypsin) on the acute inflammatory response in patients with ST-segment elevation myocardial infarction (from the VCU-alpha 1-RT pilot study).
Academic Article Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: the Framingham Heart Study.
Academic Article Leukocyte activity in patients with ST-segment elevation acute myocardial infarction treated with anakinra.
Academic Article Serum interleukin-1 (IL-1) activity in alcoholic hepatitis.
Academic Article Both inflammatory and endocrine mediators stimulate host responses to sepsis.
Academic Article A 36-year-old woman with recurrent high-grade fevers, hypotension, and hypertriglyceridemia.
Academic Article Measuring circulating cytokines.
Academic Article Influence of dietary fatty acids on cytokine production and its clinical implications.
Academic Article An expanding role for interleukin-1 blockade from gout to cancer.
Academic Article Cytokine measurements in septic shock.
Academic Article Nocardiosis in a child with chronic granulomatous disease.
Academic Article Cellular interactions in the generation and expression of histamine-induced suppressor activity.
Academic Article Comparison of chemical analyses of hollow-fiber dialyzer extracts.
Academic Article Anti-interleukin-1 reactive cells in Hodgkin's disease.
Academic Article Isolation of an interleukin-1-like factor from human joint effusions.
Academic Article George Clowes' classic paper and the search for "muscle proteolysis factor".
Academic Article An overview on interleukin-1 as a therapeutic agent.
Academic Article Effects of progressive resistance training on immune response in aging and chronic inflammation.
Academic Article IL-2 receptor gene activation by ATL-derived factor (ADF).
Academic Article Inhibition of cyclo-oxygenase attenuates the metabolic response to endotoxin in humans.
Academic Article Partial purification of human leukocytic pyrogen.
Academic Article Interleukin 1 reduces opioid binding in guinea pig brain.
Academic Article Production of endogenous pyrogen.
Academic Article Effect of prophylactic colchicine therapy on leukocyte function in patients with familial Mediterranean fever.
Academic Article Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.
Academic Article Biologic activities of interleukin-1 relevant to rheumatic diseases.
Academic Article Interleukin-1 immunoreactive innervation of the human hypothalamus.
Academic Article Biology of interleukin 1.
Academic Article Anti-inflammatory therapies in acute coronary syndromes: is IL-1 blockade a solution?
Academic Article Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans.
Academic Article Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
Academic Article An anti-inflammatory property of Candida albicans ?-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Academic Article Comparative safety of interleukin-1 blockade with anakinra in patients with ST-segment elevation acute myocardial infarction (from the VCU-ART and VCU-ART2 pilot studies).
Academic Article Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37.
Academic Article Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.
Academic Article Treating pulmonary silicosis by blocking interleukin 1.
Academic Article Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance.
Academic Article IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.
Academic Article Inflammasome-independent regulation of IL-1-family cytokines.
Academic Article Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.
Academic Article Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.
Academic Article Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses.
Academic Article Neuroinflammation in Alzheimer's disease.
Academic Article Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels.
Academic Article The histone deacetylase inhibitor panobinostat lowers biomarkers of cardiovascular risk and inflammation in HIV patients.
Academic Article Anakinra treatment in drug-resistant Behcet's disease: a case series.
Academic Article Interleukin-37 Expression Is Increased in Chronic HIV-1-Infected Individuals and Is Associated with Inflammation and the Size of the Total Viral Reservoir.
Academic Article IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.
Academic Article Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra.
Academic Article IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance.
Academic Article a1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression.
Academic Article Cytokine inhibition in chronic fatigue syndrome patients: study protocol for a randomized controlled trial.
Academic Article IL-1a is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.
Academic Article Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies.
Academic Article Safety and Efficacy of Anakinra in Severe Hidradenitis Suppurativa: A Randomized Clinical Trial.
Academic Article Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.
Academic Article Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases.
Academic Article Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines.
Academic Article Inflammation in rheumatology in 2015: New tools to tackle inflammatory arthritis.
Academic Article Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo.
Academic Article MHC class II super-enhancer increases surface expression of HLA-DR and HLA-DQ and affects cytokine production in autoimmune vitiligo.
Academic Article IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Academic Article Suppression of innate inflammation and immunity by interleukin-37.
Academic Article Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1? and by the induction of endogenous IL-1Ra.
Academic Article Reduction in C-reactive protein indicates successful targeting of the IL-1/IL-6 axis resulting in improved survival in early stage multiple myeloma.
Academic Article Toll-like receptors and chronic inflammation in rheumatic diseases: new developments.
Academic Article Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study.
Academic Article Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance.
Academic Article Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition.
Academic Article Treating Life-Threatening Myocarditis by Blocking Interleukin-1.
Academic Article Understanding human immune function using the resources from the Human Functional Genomics Project.
Academic Article Response of Steroid-Refractory Acute GVHD to a1-Antitrypsin.
Academic Article Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in?vivo.
Academic Article Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Academic Article Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.
Academic Article Interleukin-1 as a mediator of fatigue in disease: a narrative review.
Academic Article IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis.
Academic Article Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.
Academic Article Alarmins: Feel the Stress.
Academic Article a-Linoleic acid enhances the capacity of a-1 antitrypsin to inhibit lipopolysaccharide induced IL-1? in human blood neutrophils.
Academic Article IL-1 Inhibition and Vascular Function in CKD.
Academic Article Host and Environmental Factors Influencing Individual Human Cytokine Responses.
Academic Article Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species.
Academic Article Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance.
Academic Article Cytokine Inhibition in Patients With Chronic Fatigue Syndrome: A Randomized Trial.
Academic Article NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing apoptosis in metastatic melanoma.
Academic Article Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects.
Academic Article Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.
Academic Article IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells.
Grant Pathogenesis of Fever in Man
Grant Pathogenesis of Fever in Man
Grant Heterogeneous Neutrophil Responses in Acute Lung Injury
Grant PATHOGENESIS OF FEVER IN HUMANS
Academic Article Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.
Academic Article Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.
Academic Article IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.
Academic Article Interleukin-32 in chronic inflammatory conditions is associated with a higher risk of cardiovascular diseases.
Academic Article IL-32? promotes the healing of murine cutaneous lesions caused by Leishmania braziliensis infection in contrast to Leishmania amazonensis.
Academic Article The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice.
Academic Article Vorinostat plus tacrolimus/methotrexate to prevent GVHD after myeloablative conditioning, unrelated donor HCT.
Academic Article A guiding map for inflammation.
Academic Article MABp1 Targeting IL-1a for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study.
Academic Article Ethanol-mediated suppression of IL-37 licenses alcoholic liver disease.
Academic Article Suppression of inflammation and acquired immunity by IL-37.
Academic Article Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity.
Academic Article Biology of IL-38 and its role in disease.
Academic Article Overview of the IL-1 family in innate inflammation and acquired immunity.
Academic Article OLT1177, a ?-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Academic Article a1-Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease.
Academic Article Role of glutathione metabolism in host defense against Borrelia burgdorferi infection.
Academic Article Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Academic Article Human Interleukin-32? Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.
Academic Article Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes.
Academic Article Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue.
Academic Article IL-37 Expression Reduces Lean Body Mass in Mice by Reducing Food Intake.
Academic Article Treatment of Dilated Cardiomyopathy With Interleukin-1 Inhibition.
Academic Article The selective ROCK2 inhibitor KD025 reduces IL-17 secretion in human peripheral blood mononuclear cells independent of IL-1 and IL-6.
Academic Article TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization.
Academic Article An Interleukin-1 Signature in Breast Cancer Treated with Interleukin-1 Receptor Blockade: Implications for Treating Cytokine Release Syndrome of Checkpoint Inhibitors.
Academic Article IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment.
Academic Article The Inter-Relationship of Platelets with Interleukin-1?-Mediated Inflammation in Humans.
Academic Article Blocking IL-1? reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
Academic Article Interleukin-1a as an intracellular alarmin in cancer biology.
Academic Article Interleukin-1 receptor antagonist levels predict favorable outcome after bermekimab, a first-in-class true human interleukin-1a antibody, in a phase III randomized study of advanced colorectal cancer.
Academic Article Efficacy of canakinumab as first-line biologic agent in adult-onset Still's disease.
Academic Article Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression.
Academic Article Interleukin-37 monomer is the active form for reducing innate immunity.
Concept Human Umbilical Vein Endothelial Cells
Academic Article Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.
Academic Article Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome.
Academic Article Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.
Academic Article The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis.
Academic Article IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
Academic Article Targeting innate immune mediators in type 1 and type 2 diabetes.
Academic Article Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.
Academic Article PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis.
Academic Article Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout.
Academic Article Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease.
Academic Article MABp1 targeting interleukin-1a in hidradenitis suppurativa ineligible for adalimumab treatment: results of the open-label extension period.
Academic Article Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans.
Academic Article Early IL-1 receptor blockade in severe inflammatory respiratory failure complicating COVID-19.
Academic Article IL-18 and infections: Is there a role for targeted therapies?
Academic Article Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma.
Academic Article Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects.
Academic Article IL-37 Expression Is Downregulated in Lesional Psoriasis Skin.
Academic Article The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer's disease.
Academic Article Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.
Academic Article IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8.
Academic Article Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.
Academic Article Interleukin 1a: a comprehensive review on the role of IL-1a in the pathogenesis and treatment of autoimmune and inflammatory diseases.
Academic Article Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells.
Academic Article Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
Academic Article IL-38 prevents induction of trained immunity by inhibition of mTOR signaling.
Academic Article Modulation of Liver Inflammation and Fibrosis by Interleukin-37.
Academic Article The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.
Academic Article A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.
Academic Article Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses.
Academic Article Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation.
Academic Article Interleukins in cancer: from biology to therapy.
Academic Article Editorial: Cytokines and Intestinal Mucosal Immunity.
Academic Article Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.
Academic Article Tumor NLRP3-Derived IL-1? Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression.
Academic Article Urate-induced epigenetic modifications in myeloid cells.
Academic Article Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery-on-a-chip.
Academic Article Interleukin-1 Receptor Antagonism Abrogates Acute Pressure Overload-Induced Murine Heart Failure.
Academic Article IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33.
Academic Article The NLRP3 inflammasome inhibitor, OLT1177? , ameliorates experimental allergic asthma in mice.
Academic Article Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs.
Academic Article Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions.
Academic Article Circulating interleukin-38 concentrations in healthy adults.
Academic Article Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3.
Academic Article Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions.
Academic Article Exploratory analysis of interleukin-38 in hospitalized COVID-19 patients.
Academic Article IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model.
Academic Article Opposing Effects of Interleukin-36? and Interleukin-38 on Trained Immunity.
Academic Article Pharmacologic inhibition of NLRP3 reduces the levels of a-synuclein and protects dopaminergic neurons in a model of Parkinson's disease.
Academic Article Perspective: Daniela Novick, cytokines and their receptors.
Academic Article Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions.

Search Criteria
  • Humans

Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)