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Search Results to Charles A Dinarello

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One or more keywords matched the following items that are connected to Dinarello, Charles

Item TypeName
Academic Article Cytokine-processing enzymes. Stopping the cuts.
Academic Article Response to local inflammation of IL-1 beta-converting enzyme- deficient mice.
Academic Article Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice.
Academic Article Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.
Academic Article Modulation of acute myeloblastic leukemia (AML) cell proliferation and blast colony formation by antisense oligomer for IL-1 beta converting enzyme (ICE) and IL-1 receptor antagonist (IL-1ra).
Academic Article Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme.
Academic Article Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).
Academic Article IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor.
Academic Article Biologic basis for interleukin-1 in disease.
Academic Article Role of interferon regulatory factor-1 in the regulation of IL-18 production and activity.
Academic Article Novel targets for interleukin 18 binding protein.
Academic Article IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.
Academic Article Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.
Academic Article Caspase-1-deficient mice are protected against cisplatin-induced apoptosis and acute tubular necrosis.
Academic Article An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor.
Academic Article Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney.
Academic Article The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines.
Academic Article Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.
Academic Article Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta.
Academic Article IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.
Academic Article Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury.
Academic Article Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta.
Academic Article Interleukin 32 (IL-32) contains a typical a-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.
Academic Article Endotoxemic acute renal failure is attenuated in caspase-1-deficient mice.
Academic Article Interleukin-1.
Academic Article Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process.
Academic Article Modulatory in vitro effects of interleukin-1 receptor antagonist (IL-1Ra) or antisense oligonucleotide to interleukin-1 beta converting enzyme (ICE) on acute myeloid leukaemia (AML) cell growth.
Academic Article Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors.
Academic Article Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure.
Academic Article Proximal tubules from caspase-1-deficient mice are protected against hypoxia-induced membrane injury.
Academic Article Unraveling the NALP-3/IL-1beta inflammasome: a big lesson from a small mutation.
Academic Article A signal for the caspase-1 inflammasome free of TLR.
Academic Article IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Academic Article Interleukin-32 induces the differentiation of monocytes into macrophage-like cells.
Academic Article Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Academic Article Interleukin-18 and the pathogenesis of inflammatory diseases.
Academic Article Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.
Academic Article Mutations in cryopyrin: bypassing roadblocks in the caspase 1 inflammasome for interleukin-1beta secretion and disease activity.
Academic Article Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
Academic Article Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.
Academic Article Immunological and inflammatory functions of the interleukin-1 family.
Academic Article Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta.
Academic Article A clinical perspective of IL-1? as the gatekeeper of inflammation.
Academic Article Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.
Concept Caspase 8
Concept Caspase 1
Concept Caspase 2
Concept Caspase 9
Concept Caspase 3
Concept Caspase 7
Academic Article The C3a receptor, caspase-1, and release of IL-1?.
Academic Article Interleukin-37.
Academic Article Interleukin-1? in innate inflammation, autophagy and immunity.
Academic Article Interleukin-18, more than a Th1 cytokine.
Academic Article Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Academic Article Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
Academic Article Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.
Academic Article Alternatively spliced isoforms of IL-32 differentially influence cell death pathways in cancer cell lines.
Academic Article Inflammation in rheumatology in 2015: New tools to tackle inflammatory arthritis.
Academic Article Suppression of innate inflammation and immunity by interleukin-37.
Academic Article Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition.
Grant Pathogenesis of Fever in Man
Academic Article OLT1177, a ?-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Concept Caspase Inhibitors

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