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Academic Article Fever, interleukin-1 and host defense against malignancy.
Academic Article Human monocyte-derived soluble product(s) has an accessory function in the generation of histamine- and concanavalin A-induced suppressor T cells.
Academic Article The role of interleukin 1 in human B cell activation: inhibition of B cell proliferation and the generation of immunoglobulin-secreting cells by an antibody against human leukocytic pyrogen.
Academic Article The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1).
Academic Article The effects of interleukin 1 on human B cell activation and proliferation.
Academic Article Direct effects of a monoclonal B cell differentiation factor and of purified interleukin 1 on B cell differentiation.
Academic Article Immunodeficiency with defective T-cell response to interleukin 1.
Academic Article Demonstration of a circulating suppressor factor of thymocyte proliferation during endotoxin fever in humans.
Academic Article Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation.
Academic Article Cross-linking of the beta-glucan receptor on human monocytes results in interleukin-1 receptor antagonist but not interleukin-1 production.
Academic Article Interleukin-10 enhances human immunodeficiency virus type 1 expression in a chronically infected promonocytic cell line (U1) by a tumor necrosis factor alpha-independent mechanism.
Academic Article Human vascular smooth muscle cells produce an intracellular form of interleukin-1 receptor antagonist.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells.
Academic Article Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells.
Academic Article Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans.
Academic Article Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10.
Academic Article Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro.
Academic Article The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1.
Academic Article Interleukin-1 favours the in vitro development of type 2 T helper (Th2) human T-cell clones.
Academic Article Induction of circulating antagonists to IL-1 and TNF by IL-2 administration and their effects on IL-2 induced cytokine production in vitro.
Academic Article Gender differences in IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist secretion from mononuclear cells and urinary excretion.
Academic Article Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.
Academic Article Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1.
Academic Article Interleukin-13 (IL-13) induces IL-1 receptor antagonist gene expression and protein synthesis in peripheral blood mononuclear cells: inhibition by an IL-4 mutant protein.
Academic Article Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis.
Academic Article Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells.
Academic Article A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis.
Academic Article Bacterial lipopolysaccharide induction of IL-6 in rat telencephalic cells is mediated in part by IL-1.
Academic Article Expression of interleukin-1 receptor antagonist (IL-1ra) by human circulating polymorphonuclear cells.
Academic Article Role of interleukin 1 in antigen-specific T cell proliferation.
Academic Article Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2.
Academic Article Effect of endotoxin in IL-1 beta-deficient mice.
Academic Article Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors.
Academic Article Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis.
Academic Article Langerhans cell production of interleukin-1.
Academic Article Mechanism of action of cyclosporin A. Effect on T-cell-binding of interleukin 1 and antagonizing effect of insulin.
Academic Article Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.
Academic Article [Demonstration of a bacterial structure in two human mediators: a sleep facilitating factor and a monokine].
Academic Article Hyperosmotic stress as a stimulant for proinflammatory cytokine production.
Academic Article Glycosylation of the interleukin-1 receptor type I is required for optimal binding of interleukin-1.
Academic Article Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells.
Academic Article The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity.
Academic Article Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays.
Academic Article Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells.
Academic Article Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice.
Academic Article Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells.
Academic Article Modulation of acute myeloblastic leukemia (AML) cell proliferation and blast colony formation by antisense oligomer for IL-1 beta converting enzyme (ICE) and IL-1 receptor antagonist (IL-1ra).
Academic Article Leptin deficiency enhances sensitivity to endotoxin-induced lethality.
Academic Article IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family.
Academic Article Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells.
Academic Article Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipopolysaccharide-induced cytokine synthesis by human monocytes.
Academic Article Interleukin 18 stimulates HIV type 1 in monocytic cells.
Academic Article Interleukin-18 enhances lipopolysaccharide-induced interferon-gamma production in human whole blood cultures.
Academic Article Interleukin-18.
Academic Article Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.
Academic Article Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18.
Academic Article Interleukin-1 (IL-1) receptor antagonist prevents Staphylococcus epidermidis-induced hypotension and reduces circulating levels of tumor necrosis factor and IL-1 beta in rabbits.
Academic Article Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18.
Academic Article IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-gamma.
Academic Article Modulation of cell proliferation and cytokine production in AML by recombinant interleukin-1 receptor antagonist.
Academic Article IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor.
Academic Article Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event.
Academic Article Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice.
Academic Article Acellular components of Chlamydia pneumoniae stimulate cytokine production in human blood mononuclear cells.
Academic Article The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense.
Academic Article Angiotensin-converting-enzyme inhibitors suppress synthesis of tumour necrosis factor and interleukin 1 by human peripheral blood mononuclear cells.
Academic Article Osmotic regulation of cytokine synthesis in vitro.
Academic Article Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain.
Academic Article Tumor necrosis factor (TNF)-alpha-induced interleukin-8 in human blood cultures discriminates neutralization by the p55 and p75 TNF soluble receptors.
Academic Article Both E6 and E7 oncoproteins of human papillomavirus 16 inhibit IL-18-induced IFN-gamma production in human peripheral blood mononuclear and NK cells.
Academic Article An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding.
Academic Article The p38 mitogen-activated protein kinase pathway plays a critical role in thrombin-induced endothelial chemokine production and leukocyte recruitment.
Academic Article Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18.
Academic Article Non-LPS components of Chlamydia pneumoniae stimulate cytokine production through Toll-like receptor 2-dependent pathways.
Academic Article Rat interleukin-18 binding protein: cloning, expression, and characterization.
Academic Article Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells.
Academic Article Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study.
Academic Article Taurolidine, an analogue of the amino acid taurine, suppresses interleukin 1 and tumor necrosis factor synthesis in human peripheral blood mononuclear cells.
Academic Article Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells.
Academic Article Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells.
Academic Article A continuous delivery system of IL-1 receptor antagonist reduces angiogenesis and inhibits tumor development.
Academic Article Interleukin 4 (IL) 4 up-regulates gene and surface IL 1 receptor type I in murine T helper type 2 cells.
Academic Article Identification of a critical Ig-like domain in IL-18 receptor alpha and characterization of a functional IL-18 receptor complex.
Academic Article Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells.
Academic Article Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.
Academic Article Effect of advanced glycation end products on endotoxin-induced TNF-alpha, IL-1beta and IL-8 in human peripheral blood mononuclear cells.
Academic Article Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
Academic Article Differential effects of IL-1 alpha and IL-1 beta on tumorigenicity patterns and invasiveness.
Academic Article Frontline: interferon regulatory factor-1 as a protective gene in intestinal inflammation: role of TCR gamma delta T cells and interleukin-18-binding protein.
Academic Article Cytokines as potential therapeutic targets for inflammatory skin diseases.
Academic Article IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Academic Article Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules.
Academic Article Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.
Academic Article T cell-mediated hepatic inflammation modulates adiponectin levels in mice: role of tumor necrosis factor alpha.
Academic Article Mycobacterium tuberculosis induces interleukin-32 production through a caspase- 1/IL-18/interferon-gamma-dependent mechanism.
Academic Article Ambroxol inhibits interleukin 1 and tumor necrosis factor production in human mononuclear cells.
Academic Article Pro-interleukin-1 beta production by a subpopulation of human T cells, but not NK cells, in response to interleukin-2.
Academic Article Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells.
Academic Article The role of protein kinase C in interleukin 1 and tumor necrosis factor alpha induction of fibroblasts to produce and release granulocyte-macrophage colony-stimulating activity.
Academic Article Differential effects of anti-IL-1R accessory protein antibodies on IL-1alpha or IL-1beta-induced production of PGE(2) and IL-6 from 3T3-L1 cells.
Academic Article Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1).
Academic Article Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis.
Academic Article Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF.
Academic Article Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells.
Academic Article Dissociation between interleukin-1 beta mRNA and protein synthesis in human peripheral blood mononuclear cells.
Academic Article Proteinase 3-processed form of the recombinant IL-32 separate domain.
Academic Article Identification of the most active interleukin-32 isoform.
Academic Article Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood.
Academic Article IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation.
Academic Article Modulation of muramyl dipeptide stimulation of cytokine production by blood components.
Academic Article Cutting edge: Negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3.
Academic Article IL-18 neutralization ameliorates obstruction-induced epithelial-mesenchymal transition and renal fibrosis.
Academic Article Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling.
Academic Article Interleukin 1 and myelin basic protein synergistically augment adoptive transfer activity of lymphocytes mediating experimental autoimmune encephalomyelitis in Lewis rats.
Academic Article Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis.
Academic Article Purified interleukin-1 (IL-1) from human monocytes stimulates acute-phase protein synthesis by rodent hepatocytes in vitro.
Academic Article Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.
Academic Article IL-1 production by T6 (CD1a) positive cord blood mononuclear cells (Langerhan's cell precursors?).
Academic Article Cytokine gene expression and synthesis by human megakaryocytic cells.
Academic Article Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta.
Academic Article Modulation of human chondrocyte metabolism by recombinant human interferon gamma: in-vitro effects on basal and IL-1-stimulated proteinase production, cartilage degradation and DNA synthesis.
Academic Article IL-32gamma and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2.
Academic Article Inhibition of interleukin-1 production by 1,25-dihydroxyvitamin D3.
Academic Article IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.
Academic Article Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1a.
Academic Article Synergy of helper factors in the differentiation of in vivo-preactivated antigen-specific human B cells.
Academic Article The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ? cells in vivo and in vitro.
Academic Article Protection from RNA and DNA viruses by IL-32.
Academic Article A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures.
Academic Article Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury.
Academic Article Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta.
Academic Article Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein.
Academic Article Tumour necrosis factor production in Falciparum malaria and its association with schizont rupture.
Academic Article Inhibition of IL-32 activation by a-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
Academic Article IL-1a and IL-1? recruit different myeloid cells and promote different stages of sterile inflammation.
Academic Article IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease.
Academic Article Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1a.
Academic Article The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
Academic Article Interleukin 32 (IL-32) contains a typical a-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.
Academic Article IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Academic Article IL-12 and IL-18 induce MAP kinase-dependent adhesion of T cells to extracellular matrix components.
Academic Article Interleukin-1 stimulates prostaglandin biosynthesis by human amnion.
Academic Article Membrane interleukin-18 revisits membrane IL-1a in T-helper type 1 responses.
Academic Article The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses.
Academic Article Role of IL-18 in second-hand smoke-induced emphysema.
Academic Article Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.
Academic Article IL-2 receptor(p55)/Tac-inducing factor. Purification and characterization of adult T cell leukemia-derived factor.
Academic Article Lymphokines and bile secretion in the rat.
Academic Article The role of interleukin 1 (IL 1) in tumor-NK cell interactions: correction of defective NK cell activity in cancer patients by treating target cells with IL 1.
Academic Article Release of lymphokines after Epstein Barr virus infection in vitro. I. Sources of and kinetics of production of interferons and interleukins in normal humans.
Academic Article Interleukin-1: amino acid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin).
Academic Article Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells.
Academic Article Vascular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF.
Academic Article Induction by toxic-shock-syndrome toxin-1 of a circulating tumor necrosis factor-like substance in rabbits and of immunoreactive tumor necrosis factor and interleukin-1 from human mononuclear cells.
Academic Article Recombinant interleukin 1 and tumor necrosis factor acting in synergy to release thromboxane, 6-KETO-PGF1 alpha and PGE2 by human neutrophils.
Academic Article Lymphoblastoid B cell lines produce an interleukin-1-like activity that can be serologically distinct from macrophage interleukin-1.
Academic Article Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.
Academic Article Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans.
Academic Article Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies.
Academic Article IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma.
Academic Article Restoration of anti-interleukin-1 depressed natural killer activity by human recombinant interferon alpha or gamma, human recombinant interleukin-2 and indomethacin.
Academic Article Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1.
Academic Article Concentrations of immunoreactive human tumor necrosis factor alpha produced by human mononuclear cells in vitro.
Academic Article C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha.
Academic Article Induction of circulating tumor necrosis factor (TNF alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients.
Academic Article Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.
Academic Article The multiple biological properties of interleukin-1 influencing immunocompetent cells.
Academic Article Interleukins.
Academic Article Dissimilarities between purified human interleukin-1 and recombinant human interleukin-2 in the induction of fever, brain prostaglandin, and acute-phase protein synthesis.
Academic Article Fish lymphocytes respond to human IL-1.
Academic Article Interleukin-1 lymphocyte chemotactic activity in rheumatoid arthritis synovial fluid.
Academic Article Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells.
Academic Article Human thymic epithelial cells produce interleukin 1.
Academic Article Effects of human interleukin 1 and human tumor necrosis factor on human T lymphocyte colony formation.
Academic Article Development and use of a radioimmunoassay for human interleukin-1 beta.
Academic Article Interleukin 1 production by human lung tissue. I. Identification and characterization.
Academic Article Self-regulation of procoagulant events on the endothelial cell surface.
Academic Article A switch to high-flux helixone membranes reverses suppressed interferon-gamma production in patients on low-flux dialysis.
Academic Article Interleukin-1.
Academic Article Demonstration of a human pyrogen-inducing factor during mixed leukocyte reactions.
Academic Article Cleavage of human interleukin 1: isolation of a peptide fragment from plasma of febrile humans and activated monocytes.
Academic Article Reduced mitogen stimulation of DNA synthesis in human lymphocytes by a human recombinant interleukin-1 receptor antagonist.
Academic Article Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor.
Academic Article Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated.
Academic Article IL-18 cDNA vaccination protects mice from spontaneous lupus-like autoimmune disease.
Academic Article Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism.
Academic Article The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription.
Academic Article Comparison of first use and reuse of cuprophan membranes on interleukin-1 receptor antagonist and interleukin-1 beta production by blood mononuclear cells.
Academic Article Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats.
Academic Article Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.
Academic Article Soluble tumor necrosis factor receptors inhibit phorbol myristate acetate and cytokine-induced HIV-1 expression chronically infected U1 cells.
Academic Article IL-6 and IL-8 production from cultured human endothelial cells stimulated by infection with Rickettsia conorii via a cell-associated IL-1 alpha-dependent pathway.
Academic Article Synthesis of tumor necrosis factor alpha and interleukin-1 receptor antagonist, but not interleukin-1, by human mononuclear cells is enhanced by exposure of whole blood to shear stress.
Academic Article Lipopolysaccharide induces human interleukin-1 receptor antagonist and interleukin-1 production in the same cell.
Academic Article Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression.
Academic Article Protodyne: an immunostimulatory protein component, prepared from gram-positive Bacillus subtilis.
Academic Article Thrombin induces endothelial type II activation in vitro: IL-1 and TNF-alpha-independent IL-8 secretion and E-selectin expression.
Academic Article Regulation of T cell-mediated hepatic inflammation by adiponectin and leptin.
Academic Article Macrophage inflammatory protein-1 alpha production in lipopolysaccharide-stimulated human adherent blood mononuclear cells is inhibited by the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine.
Academic Article Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood.
Academic Article Oral (n-3) fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison between young and older women.
Academic Article Interleukin-1beta-induced rat pancreatic islet nitric oxide synthesis requires both the p38 and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases.
Academic Article Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.
Academic Article Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response.
Academic Article Interleukin-1 (IL-1) receptor blockade reduces endotoxin and Borrelia burgdorferi-stimulated IL-8 synthesis in human mononuclear cells.
Academic Article Interleukin-1 down-regulates gene and surface expression of interleukin-1 receptor type I by destabilizing its mRNA whereas interleukin-2 increases its expression.
Academic Article Modulatory in vitro effects of interleukin-1 receptor antagonist (IL-1Ra) or antisense oligonucleotide to interleukin-1 beta converting enzyme (ICE) on acute myeloid leukaemia (AML) cell growth.
Academic Article Adherent cell function in murine T-lymphocyte antigen recognition. IV. Enhancement of murine T-cell antigen recognition by human leukocytic pyrogen.
Academic Article Diminished in vitro production of interleukin-1 and tumor necrosis factor-alpha during acute visceral leishmaniasis and recovery after therapy.
Academic Article Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
Academic Article Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors.
Academic Article Tumor necrosis factor-alpha, interleukin-1, and interferon alpha stimulate triglyceride synthesis in HepG2 cells.
Academic Article IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
Academic Article The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures.
Academic Article IL-1 is required for tumor invasiveness and angiogenesis.
Academic Article Atherogenic effects of Chlamydia pneumoniae: refuting the innocent bystander hypothesis.
Academic Article Picogram concentrations of endotoxin stimulate synthesis of IL-1 beta and TNF alpha by human peripheral blood mononuclear cells exposed to recombinant human C5a.
Academic Article Interleukin-32: a cytokine and inducer of TNFalpha.
Academic Article Comparison of the effect of interleukin 6 and interleukin 1 on collagenase and proteoglycan production by chondrocytes.
Academic Article Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice.
Academic Article Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle.
Academic Article Alveolar type II cells inhibit fibroblast proliferation: role of IL-1alpha.
Academic Article CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells.
Academic Article Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha.
Academic Article Immune phenomena involved in the in vivo regression of fibrosarcoma cells expressing cell-associated IL-1alpha.
Academic Article The effect of whole body hyperthermia on the immune cell activity of cancer patients.
Academic Article Interleukin-1 induces tumor necrosis factor (TNF) in human peripheral blood mononuclear cells in vitro and a circulating TNF-like activity in rabbits.
Academic Article Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
Academic Article Interleukin-32 induces the differentiation of monocytes into macrophage-like cells.
Academic Article Endogenous IL-32 controls cytokine and HIV-1 production.
Academic Article Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice.
Academic Article Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Academic Article IL-32-dependent effects of IL-1beta on endothelial cell functions.
Academic Article Inhibitory effects of elevated temperature on human cytokine production and natural killer activity.
Academic Article NIH conference. Immunomodulators in clinical medicine.
Academic Article Interleukin-18 and the pathogenesis of inflammatory diseases.
Academic Article IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.
Academic Article Effects of cytokines on human thymic epithelial cells in culture. II. Recombinant IL 1 stimulates thymic epithelial cells to produce IL6 and GM-CSF.
Academic Article Measurement of immunoreactive interleukin-1 beta from human mononuclear cells: optimization of recovery, intrasubject consistency, and comparison with interleukin-1 alpha and tumor necrosis factor.
Academic Article Interleukin-1 and its biologically related cytokines.
Academic Article Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease.
Academic Article The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro.
Academic Article Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.
Academic Article IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease.
Academic Article Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors.
Academic Article Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines.
Academic Article Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
Academic Article IL-1? regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.
Academic Article Interleukin-1 beta stimulates somatostatin biosynthesis in primary cultures of fetal rat brain.
Academic Article Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.
Academic Article Immunological and inflammatory functions of the interleukin-1 family.
Academic Article Host-derived interleukin-1alpha is important in determining the immunogenicity of 3-methylcholantrene tumor cells.
Academic Article A histamine-releasing factor from activated human mononuclear cells.
Academic Article Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1.
Academic Article Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
Academic Article Regulation of hepatic acute phase protein synthesis by products of interleukin 2 (IL 2)-stimulated human peripheral blood mononuclear cells.
Academic Article The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis.
Academic Article Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta.
Academic Article TREM-1 interaction with the LPS/TLR4 receptor complex.
Academic Article Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation.
Academic Article Characterization of a subclone (D10S) of the D10.G4.1 helper T-cell line which proliferates to attomolar concentrations of interleukin-1 in the absence of mitogens.
Academic Article Studies on IL-1 receptors on D10S T-helper cells: demonstration of two molecularly and antigenically distinct IL-1 binding proteins.
Academic Article Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade.
Academic Article Inflammasome activation and IL-1? and IL-18 processing during infection.
Academic Article The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering.
Academic Article The pathogenic Th17 cell response to major schistosome egg antigen is sequentially dependent on IL-23 and IL-1?.
Academic Article Differences in the synthesis and kinetics of release of interleukin 1 alpha, interleukin 1 beta and tumor necrosis factor from human mononuclear cells.
Academic Article Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children.
Academic Article Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism.
Academic Article The lysine deacetylase inhibitor Givinostat inhibits ?-cell IL-1? induced IL-1? transcription and processing.
Academic Article Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1.
Academic Article Release of lymphokines after infection with Epstein Barr virus in vitro. II. A monocyte-dependent inhibitor of interleukin 1 downregulates the production of interleukin 2 and interferon-gamma in rheumatoid arthritis.
Academic Article Interaction of IL 1 and TPA in modulation of eosinophil function.
Academic Article C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma.
Academic Article Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte-macrophage colony-stimulating factor.
Academic Article Effects of human interleukin-1 on natural killer cell activity: is fever a host defense mechanism for tumor killing?
Academic Article Inducible interleukin-1 gene expression in human vascular smooth muscle cells.
Academic Article Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium.
Academic Article Low concentrations of interleukin-1 stimulate and high concentrations inhibit insulin release from isolated rat islets of Langerhans.
Academic Article Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol.
Academic Article Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps.
Academic Article Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation.
Academic Article A single low dose of human recombinant interleukin 1 accelerates the recovery of neutrophils in mice with cyclophosphamide-induced neutropenia.
Academic Article Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.
Academic Article Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells.
Academic Article The role of IL-1? in the early tumor cell-induced angiogenic response.
Academic Article Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.
Academic Article Effect of recombinant a1-antitrypsin Fc-fused (AAT-Fc)protein on the inhibition of inflammatory cytokine production and streptozotocin-induced diabetes.
Academic Article Interleukin-1 is a chemotactic factor for human T-lymphocytes.
Academic Article Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain.
Academic Article Interleukin 1 induces endothelial cell synthesis of plasminogen activator inhibitor.
Academic Article A radioimmunoassay for human interleukin-1 alpha: measurement of IL-1 alpha produced in vitro by human blood mononuclear cells stimulated with endotoxin.
Academic Article Recombinant human tumor necrosis factors alpha and beta stimulate fibroblasts to produce hemopoietic growth factors in vitro.
Academic Article Tumor necrosis factor alpha/cachectin is a growth factor for thymocytes. Synergistic interactions with other cytokines.
Academic Article Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.
Academic Article Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.
Academic Article Interleukin 1 stimulates granulocyte macrophage colony-stimulating activity release by vascular endothelial cells.
Academic Article Physiological mechanisms contributing to increased interleukin-1 secretion.
Academic Article A new micromethod for determination of interleukin-1 production from frozen human blood mononuclear cells.
Academic Article Comparison of the bone-resorbing activity in the supernatants from phytohemagglutinin-stimulated human peripheral blood mononuclear cells with that of cytokines through the use of an antiserum to interleukin 1.
Academic Article Multiple biological activities of human recombinant interleukin 1.
Academic Article Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells.
Academic Article Differential effects of human interleukin-1 on growth of human fibroblasts and vascular smooth muscle cells.
Concept Hematopoietic Stem Cells
Concept Precursor Cells, B-Lymphoid
Concept Lymphocytes
Concept Langerhans Cells
Concept Vero Cells
Concept Epithelial Cells
Concept T-Lymphocytes, Cytotoxic
Concept Neoplastic Stem Cells
Concept HeLa Cells
Concept COS Cells
Concept CD8-Positive T-Lymphocytes
Concept Kupffer Cells
Concept T-Lymphocytes, Helper-Inducer
Concept 3T3-L1 Cells
Concept Clone Cells
Concept K562 Cells
Concept Th1 Cells
Concept NIH 3T3 Cells
Concept Dendritic Cells
Concept Endothelial Cells
Concept Blood Cells
Concept CHO Cells
Concept T-Lymphocytes, Regulatory
Concept Foam Cells
Concept CD4-Positive T-Lymphocytes
Concept Antigen-Presenting Cells
Concept Th2 Cells
Concept B-Lymphocytes
Concept 3T3 Cells
Concept Tumor Cells, Cultured
Concept Antibody-Producing Cells
Concept Bone Marrow Cells
Concept Hep G2 Cells
Concept Mast Cells
Concept Myeloid Cells
Concept Killer Cells, Natural
Concept Insulin-Secreting Cells
Concept Cells, Cultured
Concept Stem Cells
Concept T-Lymphocytes
Academic Article A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma.
Academic Article Towards a role of interleukin-32 in atherosclerosis.
Academic Article Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes.
Academic Article IL-32 promotes angiogenesis.
Academic Article Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation.
Academic Article Interleukin-1? in innate inflammation, autophagy and immunity.
Academic Article Interleukin-18, more than a Th1 cytokine.
Academic Article Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and ?-cell protection.
Academic Article Non-redundant properties of IL-1a and IL-1? during acute colon inflammation in mice.
Academic Article Acute-phase protein a1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion.
Academic Article a1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1? responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.
Academic Article Interleukin-1 affects the function of cultured human thyroid cells.
Academic Article a-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics.
Academic Article Suppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cells.
Academic Article Leukocyte activity in patients with ST-segment elevation acute myocardial infarction treated with anakinra.
Academic Article Cellular interactions in the generation and expression of histamine-induced suppressor activity.
Academic Article Anti-interleukin-1 reactive cells in Hodgkin's disease.
Academic Article IL-2 receptor gene activation by ATL-derived factor (ADF).
Academic Article Effect of prophylactic colchicine therapy on leukocyte function in patients with familial Mediterranean fever.
Academic Article Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans.
Academic Article Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.
Academic Article An anti-inflammatory property of Candida albicans ?-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism.
Academic Article Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.
Academic Article Caspase-3-independent apoptotic pathways contribute to interleukin-32?-mediated control of Mycobacterium tuberculosis infection in THP-1 cells.
Academic Article Modulation of virus-induced innate immunity and type 1 diabetes by IL-1 blockade.
Academic Article IL-1 Receptor Antagonist Chimeric Protein: Context-Specific and Inflammation-Restricted Activation.
Academic Article Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
Academic Article IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Academic Article Suppression of innate inflammation and immunity by interleukin-37.
Academic Article Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1? and by the induction of endogenous IL-1Ra.
Academic Article Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.
Academic Article Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice.
Academic Article Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects.
Academic Article IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells.
Grant PATHOGENESIS OF FEVER IN HUMANS
Academic Article Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.
Academic Article Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.
Academic Article IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia.
Grant Molecular Mechanisms of Cytokine Induced Insulin Resistance
Academic Article Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity.
Academic Article OLT1177, a ?-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Academic Article Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses.
Academic Article Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes.
Academic Article Indeed, IL-18 is more than an inducer of IFN-?.
Academic Article The selective ROCK2 inhibitor KD025 reduces IL-17 secretion in human peripheral blood mononuclear cells independent of IL-1 and IL-6.
Academic Article TLR9 and IL-1R1 Promote Mobilization of Pulmonary Dendritic Cells during Beryllium Sensitization.
Academic Article IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment.
Academic Article The Inter-Relationship of Platelets with Interleukin-1?-Mediated Inflammation in Humans.
Academic Article Blocking IL-1? reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
Academic Article Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression.
Concept Th17 Cells
Concept Human Umbilical Vein Endothelial Cells
Concept Myeloid-Derived Suppressor Cells
Concept THP-1 Cells
Concept A549 Cells
Concept HEK293 Cells
Concept RAW 264.7 Cells
Concept Triggering Receptor Expressed on Myeloid Cells-1
Academic Article Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.
Academic Article Interleukin-37 is highly expressed in regulatory T cells of melanoma patients and enhanced by melanoma cell secretome.
Academic Article IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
Academic Article OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
Academic Article Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.
Academic Article Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects.
Academic Article IL-37 Expression Is Downregulated in Lesional Psoriasis Skin.
Academic Article Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease.
Academic Article Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells.
Academic Article Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
Academic Article Modulation of Liver Inflammation and Fibrosis by Interleukin-37.
Academic Article A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.
Academic Article Reduced CXCL1 production by endogenous IL-37 expressing dendritic cells does not affect T cell activation.
Academic Article Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.
Academic Article Tumor NLRP3-Derived IL-1? Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression.
Academic Article Urate-induced epigenetic modifications in myeloid cells.
Academic Article Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery-on-a-chip.
Academic Article IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33.
Academic Article IL-1 family cytokines as drivers and inhibitors of trained immunity.
Academic Article Activation of Host-NLRP3 Inflammasome in Myeloid Cells Dictates Response to Anti-PD-1 Therapy in Metastatic Breast Cancers.
Academic Article Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3.
Academic Article Dexamethasone and OLT1177 Cooperate in the Reduction of Melanoma Growth by Inhibiting STAT3 Functions.
Academic Article Recombinant IL-37 Exerts an Anti-inflammatory Effect on Human Aortic Valve Interstitial Cells through Extracellular and Intracellular Actions.
Academic Article Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Academic Article IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1? secretion.

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