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Espinosa, Joaquin

One or more keywords matched the following items that are connected to Espinosa, Joaquin

Item Type	Name
Concept	Interferon-gamma
Concept	Receptors, Interferon
Concept	Interferon-alpha
Concept	Interferons
Concept	Interferon Type I
Academic Article	Transcriptional Responses to IFN-? Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Grant	Understanding Down Syndrome as an Interferonopathy
Academic Article	Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
Grant	JAK Inhibition in Down Syndrome
Academic Article	Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome.
Academic Article	Down Syndrome and COVID-19: A Perfect Storm?
Academic Article	Tumoural soft tissue calcification in Down syndrome: association with heterozygous germline SAMD9 mutation and hyperactive type I interferon signaling.
Academic Article	JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.
Academic Article	Specialized interferon action in COVID-19.
Academic Article	Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition.
Academic Article	Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling.
Academic Article	Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model.
Academic Article	Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome.

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