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Search Results to Robert Kuchta

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One or more keywords matched the following items that are connected to Kuchta, Robert

Item TypeName
Academic Article Inactivation of DNA polymerase alpha-primase by acrolein: loss of activity depends on the DNA substrate.
Academic Article Acyclic guanosine analogs inhibit DNA polymerases alpha, delta, and epsilon with very different potencies and have unique mechanisms of action.
Academic Article Calf thymus DNA polymerase alpha-primase: "communication" and primer-template movement between the two active sites.
Academic Article Isotopic assays of viral polymerases and related proteins.
Academic Article Interactions of calf thymus DNA polymerase alpha with primer/templates.
Academic Article Arabinofuranosyl nucleotides are not chain-terminators during initiation of new strands of DNA by DNA polymerase alpha-primase.
Academic Article Abasic template lesions are strong chain terminators for DNA primase but not for DNA polymerase alpha during the synthesis of new DNA strands.
Academic Article Polymerization of 2'-fluoro- and 2'-O-methyl-dNTPs by human DNA polymerase alpha, polymerase gamma, and primase.
Academic Article Eucaryotic DNA primase does not prefer to synthesize primers at pyrimidine rich DNA sequences when nucleoside triphosphates are present at concentrations found in whole cells.
Academic Article Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I).
Academic Article Polymerization of the triphosphates of AraC, 2',2'-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase alpha and DNA primase.
Academic Article Mechanism of DNA polymerase alpha inhibition by aphidicolin.
Academic Article Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-).
Academic Article Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity.
Academic Article Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha.
Academic Article Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha.
Academic Article Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus.
Academic Article DNA primase. Processivity and the primase to polymerase alpha activity switch.
Academic Article Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment.
Academic Article Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides.
Academic Article High density labeling of polymerase chain reaction products with the fluorescent base analogue tCo.
Academic Article Photoinitiator nucleotide for quantifying nucleic Acid hybridization.
Academic Article Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: primase and the family X polymerases share significant sequence homology.
Academic Article Eukaryotic DNA primase.
Academic Article The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting.
Academic Article Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple noncognate nucleotides by DNA polymerase alpha.
Academic Article DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity.
Academic Article Inhibition of DNA primase and polymerase alpha by arabinofuranosylnucleoside triphosphates and related compounds.
Academic Article A mass spectrometry-based approach for identifying novel DNA polymerase substrates from a pool of dNTP analogues.
Academic Article Inhibition of DNA primase by 9-beta-D-arabinofuranosyladenosine triphosphate.
Academic Article Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase alpha.
Academic Article Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase.
Academic Article Kinetic and structural investigations of the replicative fidelity of the Klenow fragment.
Academic Article B family DNA polymerases asymmetrically recognize pyrimidines and purines.
Academic Article Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity.
Academic Article Kinetic mechanism of DNA polymerase I (Klenow).
Concept DNA Polymerase II
Concept RNA-Directed DNA Polymerase
Concept DNA-Directed DNA Polymerase
Concept DNA Polymerase III
Concept DNA Polymerase I
Concept DNA Polymerase beta
Academic Article Polymerase and exonuclease activities in herpes simplex virus type 1 DNA polymerase are not highly coordinated.
Academic Article Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.
Grant A High-Throughput Assay for Influenza Replicase/RNA Polymerase Inhibitors
Grant Mechanism and Inhibition of Herpes Replication
Grant Interaction of DNA Polymerase alpha with Novel Base-Pairs
Grant Mechanism of DNA Polymerase Alpha-Primase
Academic Article Protein Displacement by Herpes Helicase-Primase and the Key Role of UL42 during Helicase-Coupled DNA Synthesis by the Herpes Polymerase.
Concept DNA Polymerase gamma

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