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Search Results to Andrew M Thorburn

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One or more keywords matched the following items that are connected to Thorburn, Andrew

Item TypeName
Academic Article An apoptosis signaling pathway induced by the death domain of FADD selectively kills normal but not cancerous prostate epithelial cells.
Academic Article Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.
Academic Article Recruitment of TRADD, FADD, and caspase 8 to double-stranded RNA-triggered death inducing signaling complexes (dsRNA-DISCs).
Academic Article The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation.
Academic Article Acute-myeloid-leukemia-targeted toxins kill tumor cells by cell-type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death.
Academic Article Measurement of caspase activity in individual cells reveals differences in the kinetics of caspase activation between cells.
Academic Article Apoptosis by leukemia cell-targeted diphtheria toxin occurs via receptor-independent activation of Fas-associated death domain protein.
Academic Article Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells.
Academic Article The adaptor protein TRADD activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm.
Academic Article Activation of caspase pathways during iron chelator-mediated apoptosis.
Academic Article Caspase- and serine protease-dependent apoptosis by the death domain of FADD in normal epithelial cells.
Academic Article Death receptor-induced cell killing.
Academic Article EGFR-targeted diphtheria toxin stimulates TRAIL killing of glioblastoma cells by depleting anti-apoptotic proteins.
Concept Caspases
Grant Nuclear Signaling by TRADD
Grant FADD Signaling in Cancer Cells
Academic Article A caspase-independent way to kill cancer cells.
Grant Changing the mechanism of cancer therapeutics

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  • Caspases

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