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Search Results to Steven Allan Rosenberg

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Rosenberg, Steven

One or more keywords matched the following items that are connected to Rosenberg, Steven

Item Type	Name
Concept	Jurkat Cells
Concept	Lymphocytes
Concept	T-Lymphocytes, Cytotoxic
Concept	CD8-Positive T-Lymphocytes
Concept	T-Lymphocytes, Helper-Inducer
Concept	Clone Cells
Concept	K562 Cells
Concept	Th1 Cells
Concept	Dendritic Cells
Concept	T-Lymphocytes, Regulatory
Concept	Neoplastic Cells, Circulating
Concept	CD4-Positive T-Lymphocytes
Concept	Antigen-Presenting Cells
Concept	B-Lymphocytes
Concept	Tumor Cells, Cultured
Concept	Lymphocytes, Tumor-Infiltrating
Concept	Killer Cells, Natural
Concept	Cells, Cultured
Concept	T-Lymphocytes
Academic Article	Collapse of the tumor stroma is triggered by IL-12 induction of Fas.
Academic Article	Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma.
Academic Article	Phenotype and function of T cells infiltrating visceral metastases from gastrointestinal cancers and melanoma: implications for adoptive cell transfer therapy.
Academic Article	Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes.
Academic Article	Gene expression profiling using nanostring digital RNA counting to identify potential target antigens for melanoma immunotherapy.
Concept	HEK293 Cells
Academic Article	EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss.
Academic Article	Adoptive T-Cell Therapy for Cancer.
Academic Article	Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.
Academic Article	A High-avidity WT1-reactive T-Cell Receptor Mediates Recognition of Peptide and Processed Antigen but not Naturally Occurring WT1-positive Tumor Cells.
Academic Article	Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy.
Academic Article	Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin.
Academic Article	Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3.
Academic Article	Author Correction: Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma.
Academic Article	Utilization of primary tumor samples for cancer neoantigen discovery.
Academic Article	Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients.
Academic Article	Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma.
Academic Article	Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes.
Academic Article	Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer.
Academic Article	Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System.
Academic Article	CCR 20th Anniversary Commentary: Autologous T Cells-The Ultimate Personalized Drug for the Immunotherapy of Human Cancer.
Academic Article	Author Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.
Academic Article	Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.
Academic Article	Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression.
Academic Article	BRAF Inhibition: Bridge or Boost to T-cell Therapy?
Academic Article	Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor.
Academic Article	Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma.
Academic Article	An Efficient Single-Cell RNA-Seq Approach to Identify Neoantigen-Specific T Cell Receptors.
Academic Article	2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.
Academic Article	Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease.
Academic Article	Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors.
Academic Article	Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells are associated with clinical outcomes in NHL.
Academic Article	T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer.
Academic Article	Neoantigen Identification and Response to Adoptive Cell Transfer in Anti-PD-1 Naïve and Experienced Patients with Metastatic Melanoma.
Academic Article	Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting.
Academic Article	Persistence of CTL clones targeting melanocyte differentiation antigens was insufficient to mediate significant melanoma regression in humans.
Academic Article	A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus-associated Epithelial Cancers.
Academic Article	PD-1 identifies the patient-specific CD8? tumor-reactive repertoire infiltrating human tumors.
Academic Article	Complete regression of metastatic cervical cancer after treatment with human papillomavirus-targeted tumor-infiltrating T cells.
Academic Article	Development of a T cell receptor targeting an HLA-A*0201 restricted epitope from the cancer-testis antigen SSX2 for adoptive immunotherapy of cancer.
Academic Article	Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.
Academic Article	Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study.
Academic Article	Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes.
Academic Article	Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.
Academic Article	T-cell immunotherapy: looking forward.
Academic Article	Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model.
Academic Article	Lymphocytes as a living drug for cancer.
Academic Article	Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy.
Academic Article	Prospects for gene-engineered T cell immunotherapy for solid cancers.
Academic Article	Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes.
Academic Article	Impact of Prior Treatment on the Efficacy of Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma.
Academic Article	Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.
Academic Article	Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens.
Academic Article	Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients.
Academic Article	Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells.
Academic Article	Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.
Academic Article	Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers.
Academic Article	A novel murine T-cell receptor targeting NY-ESO-1.
Academic Article	Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma.
Academic Article	RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.
Academic Article	Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation.
Academic Article	Adoptive Cell Therapy--Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors.
Academic Article	High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Academic Article	Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.
Academic Article	Thrombotic microangiopathy in metastatic melanoma patients treated with adoptive cell therapy and total body irradiation.
Academic Article	Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain.
Academic Article	mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer.
Academic Article	Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6.
Academic Article	Tumor-infiltrating human CD4+ regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity.
Academic Article	T-cell Responses to TP53 "Hotspot" Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers.
Academic Article	LIGHT Elevation Enhances Immune Eradication of Colon Cancer Metastases.
Academic Article	Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
Academic Article	Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.
Academic Article	IL-2: the first effective immunotherapy for human cancer.
Academic Article	Exploiting the curative potential of adoptive T-cell therapy for cancer.
Academic Article	Use of the piggyBac transposon to create stable packaging cell lines for the production of clinical-grade self-inactivating ?-retroviral vectors.
Academic Article	Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers.
Academic Article	Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma.
Academic Article	A Rapid Cell Expansion Process for Production of Engineered Autologous CAR-T Cell Therapies.
Academic Article	Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics.
Academic Article	Landscape of immunogenic tumor antigens in successful immunotherapy of virally induced epithelial cancer.
Academic Article	Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial.
Academic Article	Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer.
Academic Article	Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma.
Academic Article	Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells.
Academic Article	Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation.
Academic Article	Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer.
Academic Article	T-cell therapy against cancer mutations.
Academic Article	Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer.
Academic Article	A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types.
Academic Article	Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Academic Article	Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results.
Academic Article	Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration.
Academic Article	Publisher Correction: Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial.
Academic Article	Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Academic Article	Adoptive cell transfer as personalized immunotherapy for human cancer.
Academic Article	Finding suitable targets is the major obstacle to cancer gene therapy.
Academic Article	Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions.
Academic Article	Tumor-infiltrating lymphocyte immunotherapy comes of age: a journey of development in the Surgery Branch, NCI.
Academic Article	Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.
Academic Article	Species-specific urokinase receptor ligands reduce glioma growth and increase survival primarily by an antiangiogenesis mechanism.
Academic Article	'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations.
Academic Article	A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma.
Academic Article	Immunogenicity of somatic mutations in human gastrointestinal cancers.
Academic Article	A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.
Academic Article	Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer.
Academic Article	Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity.
Academic Article	Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.
Academic Article	Tumor-reactive CD8+ T cells in metastatic gastrointestinal cancer refractory to chemotherapy.
Academic Article	Specific recognition of an FGFR2 fusion by tumor infiltrating lymphocytes from a patient with metastatic cholangiocarcinoma.
Academic Article	Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes.
Academic Article	Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Academic Article	Isolation and Characterization of an HLA-DPB1*04: 01-restricted MAGE-A3 T-Cell Receptor for Cancer Immunotherapy.
Academic Article	Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens.
Academic Article	Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Academic Article	Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.
Academic Article	A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response.
Academic Article	Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers.
Academic Article	Cell surface marker-based capture of neoantigen-reactive CD8+ T-cell receptors from metastatic tumor digests.
Academic Article	Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.
Academic Article	Outcomes of Adoptive Cell Transfer With Tumor-infiltrating Lymphocytes for Metastatic Melanoma Patients With and Without Brain Metastases.
Academic Article	Circulating Tumor DNA as an Early Indicator of Response to T-cell Transfer Immunotherapy in Metastatic Melanoma.
Academic Article	Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy.
Grant	The Immunotherapy of Animal and Human Cancer
Academic Article	Liver Metastasectomy to Obtain Tumor-Infiltrating Lymphocytes: Technical Considerations and Report on Single-Center Experience.

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