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Search Results to Todd M. Pitts

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One or more keywords matched the following items that are connected to Pitts, Todd

Item TypeName
Academic Article Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.
Academic Article The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models.
Academic Article Assessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models.
Academic Article Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.
Concept Protein Kinase Inhibitors
Academic Article Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
Academic Article Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.
Academic Article Targeting nuclear kinases in cancer: development of cell cycle kinase inhibitors.
Academic Article Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer.
Academic Article Antitumor activity of the MEK inhibitor TAK-733 against melanoma cell lines and patient-derived tumor explants.
Academic Article p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer.
Academic Article An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer.
Academic Article Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer.
Academic Article Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.
Academic Article Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.
Academic Article Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.
Academic Article Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models.
Academic Article A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer.
Academic Article BRAF fusions identified in melanomas have variable treatment responses and phenotypes.
Academic Article Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors.

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  • Protein Kinase Inhibitors

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